5IP9E

Structure of rna polymerase ii-tfiif complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Transcription initiation complex structures elucidate DNA opening.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 65
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2016-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5ip9E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5ip9E02
4A3EE 2JA8E 5M3ME 4A3GE 3S1QE 3HOYE 1EIKA 3GTQE 4A93E 3GTOE 2E2HE 3PO2E 3FKIE 3S14E 3RZDE 3S15E 1TWFE 4C3HE 2WB1H 5FJ8E 1I3QE 3S1RE 2YU9E 5C4XE 4A3IE 3S1NE 2Y0SH 2JA6E 3GTPE 3HKZH 3S1ME 2R93E 4BXXE 3PO3E 1K83E 5FLME 5M3FE 1R9TE 2B63E 4A3ME 3RZOE 4Y52E 3HOXE 4A3CE 3S2HE 1SFOE 4BBSE 1WCME 3GTLE 3S17E 5M5XE 5C3EE 3S16E 4Y7NE 3GTJE 4A3KE 2E2IE 5C4JE 3GTGE 4QIWH 1I6HE 4AYBH 1TWCE 2NVQE 1DZFA 2JA5E 2NVXE 3I4ME 3I4NE 4X6AE 1Y1WE 1Y1VE 4A3JE 4A3BE 5IP9E 3HOVE 5C44E 5IYBE 3HOWE 4C3JE 3H0GE 2NVYE 3H3VF 1TWAE 5IP7E 4BY1E 2VUME 2NVTE 3GTKE 5M5WE 3HOZE 4A3DE 4C2ME 3M3YE 4A3FE 4A3LE 2JA7E 3M4OE 1I50E 3S2DE 2E2JE 4BY7E 5IYCE 1TWGE 3CQZE 4BBRE 1TWHE 2R92E 4C3IE 3GTME 2WAQH 2PMZH 3K7AE 5M5YE 5IYDE 2R7ZE 3HOUE
chains in the Genus database with same CATH superfamily
4A3EE 4C3IF 3GTMF 2JA8E 4MEXE 5M3ME 4A3GE 5M5YF 4Q4ZE 3S1QE 5IYDF 3HOYE 2R7ZF 3S17F 3HOUF 4A3EF 2JA8F 1EIKA 3GTQE 2CW0E 4YFKE 4OINE 5M3MF 4A93E 3GTOE 5BYHE 2A69E 2E2HE 3S1QF 4A3GF 2BE5E 3PO2E 2A6EE 3FKIE 3S14E 4GZYE 3RZDE 3M3YF 3S15E 5E18E 1TWFE 4C3HE 3H3VG 3GTQF 2WB1H 5FJ8E 3GTOF 1I3QE 3S1RE 2E2HF 4A93F 2YU9E 5C4XE 3PO2F 3FKIF 1YNJK 3S14F 4A3IE 3S1NE 3RZDF 2Y0SH 4OIPE 2JA6E 3GTPE 5D4CE 3S15F 1TWFF 4C3HF 4OIOE 3HKZH 3S1ME 2R93E 5FJ8F 1I3QF 3K7AF 3S1RF 4BXXE 2WAQK 3PO3E 4XLPE 5C4XF 2PMZK 4A3IF 4JK1E 5TMCE 3S1NF 2JA6F 1HQME 3GTPF 1K83E 5FLME 5M3FE 4LJZE 4YG2E 4LK0E 5E17E 3S1MF 2R93F 3DXJE 1R9TE 2B63E 4BBRF 5D4DE 4BXXF 3PO3F 4A3LF 4A3ME 1TWGF 3HOYF 1K83F 3RZOE 5FLMF 4Q5SE 5M3FF 4Y52E 5IPLE 3HOXE 4A3CE 4XSZE 4ZH4E 3S2HE 1R9TF 1SFOE 4OIRE 2B63F 4BBSE 1WCME 4A3MF 3GTLE 3S17E 5M5XE 5C3EE 3RZOF 3S16E 4Y7NE 4Y52F 3GTJE 4A3KE 3HOXF 4A3CF 2E2IE 5C4JE 3GTGE 2PPBE 3S2HF 4QIWH 2WB1I 1SFOF 1I6HE 4KN4E 4AYBH 4BBSF 1WCMF 1TWCE 4MQ9E 2NVQE 4G7HE 2YU9F 1DZFA 2JA5E 5M5XF 2Y0SI 5C3EF 3GTLF 3S16F 4Y7NF 2O5JE 2NVXE 3GTJF 4A3KF 3I4ME 4YFXE 3WODE 5C4JF 2E2IF 3GTGF 3I4NE 1YNNK 2A6HE 4MEYE 1I6HF 4X6AE 1Y1WE 4OIQE 1TWCF 1I6VE 4YFNE 2KRXA 2NVQF 2R92F 2JA5F 5TMFE 2NVXF 1Y1VE 4G7OE 4A3JE 3I4MF 4A3BE 3I4NF 5IP9E 4X6AF 1Y1WF 3HOVE 1ZYRE 5C44E 5IYBE 3HOWE 4C3JE 3H0GE 4LK1E 2NVYE 1Y1VF 3H3VF 5D4EE 4A3JF 1TWAE 3EQLE 4A3BF 5IP7E 4BY1E 2VUME 2NVTE 5IP9F 3HOVF 4KMUE 5C44F 3GTKE 5M5WE 4LLGE 3HOZE 4A3DE 5IYBF 4C2ME 3HOWF 3M3YE 4A3FE 3H0GF 2NVYF 4C3JF 4A3LE 2JA7E 1TWAF 5IP7F 4BY1F 2VUMF 2NVTF 2O5IE 3M4OE 1I50E 3S2DE 3GTKF 5M5WF 2E2JE 3HOZF 4A3DF 4QIWK 4C2MF 4BY7E 1QKLA 4A3FF 4XSXE 5IYCE 1TWGE 3CQZE 4BBRE 1IW7E 1SMYE 1TWHE 2R92E 3HKZK 4KN7E 4AYBK 4G7ZE 2JA7F 4C3IE 3GTME 2WAQH 2PMZH 3K7AE 1I50F 4XLNE 3M4OF 3S2DF 2E2JF 5M5YE 4BY7F 5IYDE 2R7ZE 2A68E 5IYCF 3HOUE 3CQZF 1TWHF
chains in the Genus database with same CATH topology
4A3EE 2JA8E 5M3ME 4A3GE 3S1QE 3HOYE 1EIKA 3GTQE 4A93E 3GTOE 2E2HE 3PO2E 3FKIE 3S14E 3RZDE 3S15E 1TWFE 4C3HE 2WB1H 5FJ8E 1I3QE 3S1RE 2YU9E 5C4XE 4A3IE 3S1NE 2Y0SH 2JA6E 3GTPE 3HKZH 3S1ME 2R93E 4BXXE 3PO3E 1K83E 5FLME 5M3FE 1R9TE 2B63E 4A3ME 3RZOE 4Y52E 3HOXE 4A3CE 3S2HE 1SFOE 4BBSE 1WCME 3GTLE 3S17E 5M5XE 5C3EE 3S16E 4Y7NE 3GTJE 4A3KE 2E2IE 5C4JE 3GTGE 4QIWH 1I6HE 4AYBH 1TWCE 2NVQE 1DZFA 2JA5E 2NVXE 3I4ME 3I4NE 4X6AE 1Y1WE 1Y1VE 4A3JE 4A3BE 5IP9E 3HOVE 5C44E 5IYBE 3HOWE 4C3JE 3H0GE 2NVYE 3H3VF 1TWAE 5IP7E 4BY1E 2VUME 2NVTE 3GTKE 5M5WE 3HOZE 4A3DE 4C2ME 3M3YE 4A3FE 4A3LE 2JA7E 3M4OE 1I50E 3S2DE 2E2JE 4BY7E 5IYCE 1TWGE 3CQZE 4BBRE 1TWHE 2R92E 4C3IE 3GTME 2WAQH 2PMZH 3K7AE 5M5YE 5IYDE 2R7ZE 3HOUE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3E E;  2JA8 E;  5M3M E;  4A3G E;  3S1Q E;  3HOY E;  1EIK A;  3GTQ E;  4A93 E;  3GTO E;  2E2H E;  3PO2 E;  3FKI E;  3S14 E;  3RZD E;  3S15 E;  1TWF E;  4C3H E;  2WB1 H;  5FJ8 E;  1I3Q E;  3S1R E;  2YU9 E;  5C4X E;  4A3I E;  3S1N E;  2Y0S H;  2JA6 E;  3GTP E;  3HKZ H;  3S1M E;  2R93 E;  4BXX E;  3PO3 E;  1K83 E;  5FLM E;  5M3F E;  1R9T E;  2B63 E;  4A3M E;  3RZO E;  4Y52 E;  3HOX E;  4A3C E;  3S2H E;  1SFO E;  4BBS E;  1WCM E;  3GTL E;  3S17 E;  5M5X E;  5C3E E;  3S16 E;  4Y7N E;  3GTJ E;  4A3K E;  2E2I E;  5C4J E;  3GTG E;  4QIW H;  1I6H E;  4AYB H;  1TWC E;  2NVQ E;  1DZF A;  2JA5 E;  2NVX E;  3I4M E;  3I4N E;  4X6A E;  1Y1W E;  1Y1V E;  4A3J E;  4A3B E;  5IP9 E;  3HOV E;  5C44 E;  5IYB E;  3HOW E;  4C3J E;  3H0G E;  2NVY E;  3H3V F;  1TWA E;  5IP7 E;  4BY1 E;  2VUM E;  2NVT E;  3GTK E;  5M5W E;  3HOZ E;  4A3D E;  4C2M E;  3M3Y E;  4A3F E;  4A3L E;  2JA7 E;  3M4O E;  1I50 E;  3S2D E;  2E2J E;  4BY7 E;  5IYC E;  1TWG E;  3CQZ E;  4BBR E;  1TWH E;  2R92 E;  4C3I E;  3GTM E;  2WAQ H;  2PMZ H;  3K7A E;  5M5Y E;  5IYD E;  2R7Z E;  3HOU E; 
#chains in the Genus database with same CATH topology
 4A3E E;  4C3I F;  3GTM F;  2JA8 E;  4MEX E;  5M3M E;  4A3G E;  5M5Y F;  4Q4Z E;  3S1Q E;  5IYD F;  3HOY E;  2R7Z F;  3S17 F;  3HOU F;  4A3E F;  2JA8 F;  1EIK A;  3GTQ E;  2CW0 E;  4YFK E;  4OIN E;  5M3M F;  4A93 E;  3GTO E;  5BYH E;  2A69 E;  2E2H E;  3S1Q F;  4A3G F;  2BE5 E;  3PO2 E;  2A6E E;  3FKI E;  3S14 E;  4GZY E;  3RZD E;  3M3Y F;  3S15 E;  5E18 E;  1TWF E;  4C3H E;  3H3V G;  3GTQ F;  2WB1 H;  5FJ8 E;  3GTO F;  1I3Q E;  3S1R E;  2E2H F;  4A93 F;  2YU9 E;  5C4X E;  3PO2 F;  3FKI F;  1YNJ K;  3S14 F;  4A3I E;  3S1N E;  3RZD F;  2Y0S H;  4OIP E;  2JA6 E;  3GTP E;  5D4C E;  3S15 F;  1TWF F;  4C3H F;  4OIO E;  3HKZ H;  3S1M E;  2R93 E;  5FJ8 F;  1I3Q F;  3K7A F;  3S1R F;  4BXX E;  2WAQ K;  3PO3 E;  4XLP E;  5C4X F;  2PMZ K;  4A3I F;  4JK1 E;  5TMC E;  3S1N F;  2JA6 F;  1HQM E;  3GTP F;  1K83 E;  5FLM E;  5M3F E;  4LJZ E;  4YG2 E;  4LK0 E;  5E17 E;  3S1M F;  2R93 F;  3DXJ E;  1R9T E;  2B63 E;  4BBR F;  5D4D E;  4BXX F;  3PO3 F;  4A3L F;  4A3M E;  1TWG F;  3HOY F;  1K83 F;  3RZO E;  5FLM F;  4Q5S E;  5M3F F;  4Y52 E;  5IPL E;  3HOX E;  4A3C E;  4XSZ E;  4ZH4 E;  3S2H E;  1R9T F;  1SFO E;  4OIR E;  2B63 F;  4BBS E;  1WCM E;  4A3M F;  3GTL E;  3S17 E;  5M5X E;  5C3E E;  3RZO F;  3S16 E;  4Y7N E;  4Y52 F;  3GTJ E;  4A3K E;  3HOX F;  4A3C F;  2E2I E;  5C4J E;  3GTG E;  2PPB E;  3S2H F;  4QIW H;  2WB1 I;  1SFO F;  1I6H E;  4KN4 E;  4AYB H;  4BBS F;  1WCM F;  1TWC E;  4MQ9 E;  2NVQ E;  4G7H E;  2YU9 F;  1DZF A;  2JA5 E;  5M5X F;  2Y0S I;  5C3E F;  3GTL F;  3S16 F;  4Y7N F;  2O5J E;  2NVX E;  3GTJ F;  4A3K F;  3I4M E;  4YFX E;  3WOD E;  5C4J F;  2E2I F;  3GTG F;  3I4N E;  1YNN K;  2A6H E;  4MEY E;  1I6H F;  4X6A E;  1Y1W E;  4OIQ E;  1TWC F;  1I6V E;  4YFN E;  2KRX A;  2NVQ F;  2R92 F;  2JA5 F;  5TMF E;  2NVX F;  1Y1V E;  4G7O E;  4A3J E;  3I4M F;  4A3B E;  3I4N F;  5IP9 E;  4X6A F;  1Y1W F;  3HOV E;  1ZYR E;  5C44 E;  5IYB E;  3HOW E;  4C3J E;  3H0G E;  4LK1 E;  2NVY E;  1Y1V F;  3H3V F;  5D4E E;  4A3J F;  1TWA E;  3EQL E;  4A3B F;  5IP7 E;  4BY1 E;  2VUM E;  2NVT E;  5IP9 F;  3HOV F;  4KMU E;  5C44 F;  3GTK E;  5M5W E;  4LLG E;  3HOZ E;  4A3D E;  5IYB F;  4C2M E;  3HOW F;  3M3Y E;  4A3F E;  3H0G F;  2NVY F;  4C3J F;  4A3L E;  2JA7 E;  1TWA F;  5IP7 F;  4BY1 F;  2VUM F;  2NVT F;  2O5I E;  3M4O E;  1I50 E;  3S2D E;  3GTK F;  5M5W F;  2E2J E;  3HOZ F;  4A3D F;  4QIW K;  4C2M F;  4BY7 E;  1QKL A;  4A3F F;  4XSX E;  5IYC E;  1TWG E;  3CQZ E;  4BBR E;  1IW7 E;  1SMY E;  1TWH E;  2R92 E;  3HKZ K;  4KN7 E;  4AYB K;  4G7Z E;  2JA7 F;  4C3I E;  3GTM E;  2WAQ H;  2PMZ H;  3K7A E;  1I50 F;  4XLN E;  3M4O F;  3S2D F;  2E2J F;  5M5Y E;  4BY7 F;  5IYD E;  2R7Z E;  2A68 E;  5IYC F;  3HOU E;  3CQZ F;  1TWH F; 
#chains in the Genus database with same CATH homology
 4A3E E;  2JA8 E;  5M3M E;  4A3G E;  3S1Q E;  3HOY E;  1EIK A;  3GTQ E;  4A93 E;  3GTO E;  2E2H E;  3PO2 E;  3FKI E;  3S14 E;  3RZD E;  3S15 E;  1TWF E;  4C3H E;  2WB1 H;  5FJ8 E;  1I3Q E;  3S1R E;  2YU9 E;  5C4X E;  4A3I E;  3S1N E;  2Y0S H;  2JA6 E;  3GTP E;  3HKZ H;  3S1M E;  2R93 E;  4BXX E;  3PO3 E;  1K83 E;  5FLM E;  5M3F E;  1R9T E;  2B63 E;  4A3M E;  3RZO E;  4Y52 E;  3HOX E;  4A3C E;  3S2H E;  1SFO E;  4BBS E;  1WCM E;  3GTL E;  3S17 E;  5M5X E;  5C3E E;  3S16 E;  4Y7N E;  3GTJ E;  4A3K E;  2E2I E;  5C4J E;  3GTG E;  4QIW H;  1I6H E;  4AYB H;  1TWC E;  2NVQ E;  1DZF A;  2JA5 E;  2NVX E;  3I4M E;  3I4N E;  4X6A E;  1Y1W E;  1Y1V E;  4A3J E;  4A3B E;  5IP9 E;  3HOV E;  5C44 E;  5IYB E;  3HOW E;  4C3J E;  3H0G E;  2NVY E;  3H3V F;  1TWA E;  5IP7 E;  4BY1 E;  2VUM E;  2NVT E;  3GTK E;  5M5W E;  3HOZ E;  4A3D E;  4C2M E;  3M3Y E;  4A3F E;  4A3L E;  2JA7 E;  3M4O E;  1I50 E;  3S2D E;  2E2J E;  4BY7 E;  5IYC E;  1TWG E;  3CQZ E;  4BBR E;  1TWH E;  2R92 E;  4C3I E;  3GTM E;  2WAQ H;  2PMZ H;  3K7A E;  5M5Y E;  5IYD E;  2R7Z E;  3HOU E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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