5IPLE

Sigmas-transcription initiation complex with 4-nt nascent rna
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
79
structure length
79
Chain Sequence
ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
pubmed doi rcsb
molecule tags Transcription, transferase/dna/rna
source organism Escherichia coli
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 24
structure length 79
sequence length 79
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2016-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5iplE00
2NVYF 2YU9F 3I4NF 4ZH4E 2R93F 4LLGE 2BE5E 3I4MF 2WB1I 2R7ZF 3GTKF 3FKIF 4A3MF 1TWGF 2CW0E 4XLNE 3GTGF 5FJ8F 5IYBF 4G7ZE 2JA6F 4BXXF 5D4DE 1Y1WF 4A3KF 1TWFF 3M3YF 4LJZE 3PO3F 2O5JE 5M3MF 3HOYF 5E18E 1Y1VF 3H0GF 3EQLE 4Q4ZE 5TMFE 5M5WF 1I6VE 1I6HF 4XSXE 2PPBE 1ZYRE 1R9TF 3H3VG 4YG2E 4YFKE 2PMZK 4C3IF 2NVXF 3S2DF 4A3LF 3RZOF 3GTMF 3HKZK 5E17E 4OIOE 2E2JF 5TMCE 1YNNK 3M4OF 4BBRF 5D4EE 2NVQF 3GTLF 1TWHF 5IYCF 4G7OE 4OIPE 4OIRE 4C3JF 2JA8F 2B63F 1TWCF 2E2IF 5FLMF 3S16F 1K83F 3S15F 4Y52F 4GZYE 4C2MF 5C4XF 2NVTF 1I50F 2A6HE 5M5XF 4A3GF 5IPLE 3RZDF 4C3HF 4A3JF 2WAQK 4YFXE 4XSZE 4MEYE 2A6EE 1SFOF 3S14F 5IP9F 3WODE 3HOUF 1QKLA 3GTJF 5BYHE 5C4JF 4A93F 4A3EF 3GTPF 4JK1E 2R92F 4KN4E 1IW7E 4Q5SE 2VUMF 4OIQE 4A3DF 4X6AF 1TWAF 5C44F 4MEXE 3DXJE 2A69E 4LK1E 4A3BF 4AYBK 2JA7F 4MQ9E 4A3IF 5M5YF 1YNJK 3PO2F 2O5IE 3S1MF 4BY1F 4KMUE 4BY7F 4XLPE 1SMYE 5C3EF 3S17F 3HOXF 4LK0E 4A3FF 3HOVF 3S1NF 3GTOF 5D4CE 3S1RF 3S2HF 4A3CF 1I3QF 2A68E 4G7HE 4BBSF 1WCMF 3S1QF 4KN7E 3HOZF 5M3FF 3K7AF 3HOWF 2JA5F 2E2HF 3GTQF 4YFNE 5IP7F 3CQZF 2Y0SI 4OINE 4Y7NF 5IYDF 1HQME
chains in the Genus database with same CATH superfamily
2NVYF 4QIWH 2R7ZE 2YU9F 3GTKE 3I4NF 3FKIE 4ZH4E 2R93F 4A3ME 4AYBH 4LLGE 2BE5E 1TWGE 3I4MF 2WB1I 2R7ZF 3GTGE 5FJ8E 3GTKF 5IYBE 3FKIF 2JA6E 2KRXA 1TWCE 2WAQH 4A3MF 4A3KE 1TWGF 2CW0E 4XLNE 1TWFE 3GTGF 5FJ8F 3S15E 5IYBF 4G7ZE 2JA6F 3M3YE 5D4DE 1Y1WF 4BXXF 4A3KF 3PO3E 5M3ME 3HOYE 1DZFA 1TWFF 1I50E 1Y1VE 3H0GE 3M3YF 5M5WE 4LJZE 1I6HE 4A3JE 3PO3F 2O5JE 5M3MF 3HOYF 1R9TE 2Y0SH 5E18E 1Y1VF 4C3IE 2NVXE 3S2DE 3H0GF 3EQLE 5TMFE 4Q4ZE 5M5WF 3GTME 1I6VE 1I6HF 3RZOE 4XSXE 2PPBE 1ZYRE 1R9TF 2E2JE 3H3VG 4YG2E 4YFKE 2PMZK 4C3IF 2NVXF 3S2DF 3M4OE 4BBRE 3RZOF 3GTMF 3GTLE 2NVQE 4A3LF 1TWHE 3HKZK 4A3CF 5E17E 2WB1H 5IYCE 4A3EE 4OIOE 3GTPE 2JA8E 4C3JE 2E2JF 2B63E 5TMCE 1YNNK 3M4OF 4BBRF 2E2IE 5D4EE 5FLME 2NVQF 1TWHF 3GTLF 5IYCF 3S16E 4G7OE 4OIPE 4OIRE 1K83E 4C3JF 2B63F 2JA8F 4Y52E 1EIKA 1TWCF 2E2IF 5FLMF 4C2ME 5C4XE 2NVTE 3S16F 1K83F 3S15F 4QIWK 5M5XE 4Y52F 4A3GE 3RZDE 4C3HE 4GZYE 4C2MF 5C4XF 2NVTF 1I50F 2A6HE 1SFOE 5M5XF 4A3GF 3S14E 5IPLE 5IP9E 4C3HF 4A3JF 3RZDF 2WAQK 4YFXE 4XSZE 3HOUE 4MEYE 3GTJE 2A6EE 1SFOF 3S14F 5IP9F 5C4JE 4A93E 3WODE 3HOUF 1QKLA 3GTJF 2R92E 5BYHE 5C4JF 2VUME 4A3DE 4A93F 4A3EF 4X6AE 1TWAE 5C44E 3GTPF 4JK1E 2R92F 4KN4E 1IW7E 4Q5SE 2VUMF 4OIQE 4A3BE 4A3DF 2JA7E 4X6AF 1TWAF 4A3IE 5C44F 4MEXE 5M5YE 3DXJE 3PO2E 2A69E 3S1ME 4LK1E 4BY1E 4A3BF 4AYBK 2JA7F 4BY7E 4MQ9E 4A3IF 5M5YF 1YNJK 3PO2F 2O5IE 5C3EE 3S1MF 4BY1F 3S17E 3HOXE 4A3FE 3HOVE 3S1NE 3GTOE 4KMUE 4BY7F 3S1RE 4XLPE 3S2HE 1SMYE 1I3QE 4BBSE 4BXXE 4A3CE 1WCME 1Y1WE 5C3EF 3S17F 3HOXF 4LK0E 4A3FF 2PMZH 3HOVF 3GTOF 3S1QE 3S2HF 3S1NF 3HOZE 5D4CE 3S1RF 5M3FE 3H3VF 1I3QF 2A68E 3HKZH 3K7AE 4G7HE 3HOWE 1WCMF 2JA5E 2E2HE 4BBSF 3GTQE 5IP7E 3S1QF 3CQZE 4KN7E 3HOZF 4Y7NE 5M3FF 3K7AF 5IYDE 3HOWF 2JA5F 2E2HF 3GTQF 4YFNE 2NVYE 5IP7F 2YU9E 3CQZF 2Y0SI 4OINE 3I4NE 4Y7NF 2R93E 5IYDF 4A3LE 3I4ME 1HQME
chains in the Genus database with same CATH topology
2NVYF 2YU9F 3I4NF 4ZH4E 2R93F 4LLGE 2BE5E 3I4MF 2WB1I 2R7ZF 3GTKF 3FKIF 2KRXA 4A3MF 1TWGF 2CW0E 4XLNE 3GTGF 5FJ8F 5IYBF 4G7ZE 2JA6F 4BXXF 5D4DE 1Y1WF 4A3KF 1TWFF 3M3YF 4LJZE 3PO3F 2O5JE 5M3MF 3HOYF 5E18E 1Y1VF 3H0GF 3EQLE 4Q4ZE 5TMFE 5M5WF 1I6VE 1I6HF 4XSXE 2PPBE 1ZYRE 1R9TF 3H3VG 4YG2E 4YFKE 2PMZK 4C3IF 2NVXF 3S2DF 4A3LF 3RZOF 3GTMF 3HKZK 5E17E 4OIOE 2E2JF 5TMCE 1YNNK 3M4OF 4BBRF 5D4EE 2NVQF 3GTLF 1TWHF 5IYCF 4G7OE 4OIPE 4OIRE 4C3JF 2JA8F 2B63F 1TWCF 2E2IF 5FLMF 3S16F 1K83F 3S15F 4QIWK 4Y52F 4GZYE 4C2MF 5C4XF 2NVTF 1I50F 2A6HE 5M5XF 4A3GF 5IPLE 3RZDF 4C3HF 4A3JF 2WAQK 4YFXE 4XSZE 4MEYE 2A6EE 1SFOF 3S14F 5IP9F 3WODE 3HOUF 1QKLA 3GTJF 5BYHE 5C4JF 4A93F 4A3EF 3GTPF 4JK1E 2R92F 4KN4E 1IW7E 4Q5SE 2VUMF 4OIQE 4A3DF 4X6AF 1TWAF 5C44F 4MEXE 3DXJE 2A69E 4LK1E 4A3BF 4AYBK 2JA7F 4MQ9E 4A3IF 5M5YF 1YNJK 3PO2F 2O5IE 3S1MF 4BY1F 4KMUE 4BY7F 4XLPE 1SMYE 5C3EF 3S17F 3HOXF 4LK0E 4A3FF 3HOVF 3S1NF 3GTOF 5D4CE 3S1RF 3S2HF 4A3CF 1I3QF 2A68E 4G7HE 4BBSF 1WCMF 3S1QF 4KN7E 3HOZF 5M3FF 3K7AF 3HOWF 2JA5F 2E2HF 3GTQF 4YFNE 5IP7F 3CQZF 2Y0SI 4OINE 4Y7NF 5IYDF 1HQME
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVY F;  2YU9 F;  3I4N F;  4ZH4 E;  2R93 F;  4LLG E;  2BE5 E;  3I4M F;  2WB1 I;  2R7Z F;  3GTK F;  3FKI F;  4A3M F;  1TWG F;  2CW0 E;  4XLN E;  3GTG F;  5FJ8 F;  5IYB F;  4G7Z E;  2JA6 F;  4BXX F;  5D4D E;  1Y1W F;  4A3K F;  1TWF F;  3M3Y F;  4LJZ E;  3PO3 F;  2O5J E;  5M3M F;  3HOY F;  5E18 E;  1Y1V F;  3H0G F;  3EQL E;  4Q4Z E;  5TMF E;  5M5W F;  1I6V E;  1I6H F;  4XSX E;  2PPB E;  1ZYR E;  1R9T F;  3H3V G;  4YG2 E;  4YFK E;  2PMZ K;  4C3I F;  2NVX F;  3S2D F;  4A3L F;  3RZO F;  3GTM F;  3HKZ K;  5E17 E;  4OIO E;  2E2J F;  5TMC E;  1YNN K;  3M4O F;  4BBR F;  5D4E E;  2NVQ F;  3GTL F;  1TWH F;  5IYC F;  4G7O E;  4OIP E;  4OIR E;  4C3J F;  2JA8 F;  2B63 F;  1TWC F;  2E2I F;  5FLM F;  3S16 F;  1K83 F;  3S15 F;  4Y52 F;  4GZY E;  4C2M F;  5C4X F;  2NVT F;  1I50 F;  2A6H E;  5M5X F;  4A3G F;  5IPL E;  3RZD F;  4C3H F;  4A3J F;  2WAQ K;  4YFX E;  4XSZ E;  4MEY E;  2A6E E;  1SFO F;  3S14 F;  5IP9 F;  3WOD E;  3HOU F;  1QKL A;  3GTJ F;  5BYH E;  5C4J F;  4A93 F;  4A3E F;  3GTP F;  4JK1 E;  2R92 F;  4KN4 E;  1IW7 E;  4Q5S E;  2VUM F;  4OIQ E;  4A3D F;  4X6A F;  1TWA F;  5C44 F;  4MEX E;  3DXJ E;  2A69 E;  4LK1 E;  4A3B F;  4AYB K;  2JA7 F;  4MQ9 E;  4A3I F;  5M5Y F;  1YNJ K;  3PO2 F;  2O5I E;  3S1M F;  4BY1 F;  4KMU E;  4BY7 F;  4XLP E;  1SMY E;  5C3E F;  3S17 F;  3HOX F;  4LK0 E;  4A3F F;  3HOV F;  3S1N F;  3GTO F;  5D4C E;  3S1R F;  3S2H F;  4A3C F;  1I3Q F;  2A68 E;  4G7H E;  4BBS F;  1WCM F;  3S1Q F;  4KN7 E;  3HOZ F;  5M3F F;  3K7A F;  3HOW F;  2JA5 F;  2E2H F;  3GTQ F;  4YFN E;  5IP7 F;  3CQZ F;  2Y0S I;  4OIN E;  4Y7N F;  5IYD F;  1HQM E; 
#chains in the Genus database with same CATH topology
 2NVY F;  4QIW H;  2R7Z E;  2YU9 F;  3GTK E;  3I4N F;  3FKI E;  4ZH4 E;  2R93 F;  4A3M E;  4AYB H;  4LLG E;  2BE5 E;  1TWG E;  3I4M F;  2WB1 I;  2R7Z F;  3GTG E;  5FJ8 E;  3GTK F;  5IYB E;  3FKI F;  2JA6 E;  2KRX A;  1TWC E;  2WAQ H;  4A3M F;  4A3K E;  1TWG F;  2CW0 E;  4XLN E;  1TWF E;  3GTG F;  5FJ8 F;  3S15 E;  5IYB F;  4G7Z E;  2JA6 F;  3M3Y E;  5D4D E;  1Y1W F;  4BXX F;  4A3K F;  3PO3 E;  5M3M E;  3HOY E;  1DZF A;  1TWF F;  1I50 E;  1Y1V E;  3H0G E;  3M3Y F;  5M5W E;  4LJZ E;  1I6H E;  4A3J E;  3PO3 F;  2O5J E;  5M3M F;  3HOY F;  1R9T E;  2Y0S H;  5E18 E;  1Y1V F;  4C3I E;  2NVX E;  3S2D E;  3H0G F;  3EQL E;  5TMF E;  4Q4Z E;  5M5W F;  3GTM E;  1I6V E;  1I6H F;  3RZO E;  4XSX E;  2PPB E;  1ZYR E;  1R9T F;  2E2J E;  3H3V G;  4YG2 E;  4YFK E;  2PMZ K;  4C3I F;  2NVX F;  3S2D F;  3M4O E;  4BBR E;  3RZO F;  3GTM F;  3GTL E;  2NVQ E;  4A3L F;  1TWH E;  3HKZ K;  4A3C F;  5E17 E;  2WB1 H;  5IYC E;  4A3E E;  4OIO E;  3GTP E;  2JA8 E;  4C3J E;  2E2J F;  2B63 E;  5TMC E;  1YNN K;  3M4O F;  4BBR F;  2E2I E;  5D4E E;  5FLM E;  2NVQ F;  1TWH F;  3GTL F;  5IYC F;  3S16 E;  4G7O E;  4OIP E;  4OIR E;  1K83 E;  4C3J F;  2B63 F;  2JA8 F;  4Y52 E;  1EIK A;  1TWC F;  2E2I F;  5FLM F;  4C2M E;  5C4X E;  2NVT E;  3S16 F;  1K83 F;  3S15 F;  4QIW K;  5M5X E;  4Y52 F;  4A3G E;  3RZD E;  4C3H E;  4GZY E;  4C2M F;  5C4X F;  2NVT F;  1I50 F;  2A6H E;  1SFO E;  5M5X F;  4A3G F;  3S14 E;  5IPL E;  5IP9 E;  4C3H F;  4A3J F;  3RZD F;  2WAQ K;  4YFX E;  4XSZ E;  3HOU E;  4MEY E;  3GTJ E;  2A6E E;  1SFO F;  3S14 F;  5IP9 F;  5C4J E;  4A93 E;  3WOD E;  3HOU F;  1QKL A;  3GTJ F;  2R92 E;  5BYH E;  5C4J F;  2VUM E;  4A3D E;  4A93 F;  4A3E F;  4X6A E;  1TWA E;  5C44 E;  3GTP F;  4JK1 E;  2R92 F;  4KN4 E;  1IW7 E;  4Q5S E;  2VUM F;  4OIQ E;  4A3B E;  4A3D F;  2JA7 E;  4X6A F;  1TWA F;  4A3I E;  5C44 F;  4MEX E;  5M5Y E;  3DXJ E;  3PO2 E;  2A69 E;  3S1M E;  4LK1 E;  4BY1 E;  4A3B F;  4AYB K;  2JA7 F;  4BY7 E;  4MQ9 E;  4A3I F;  5M5Y F;  1YNJ K;  3PO2 F;  2O5I E;  5C3E E;  3S1M F;  4BY1 F;  3S17 E;  3HOX E;  4A3F E;  3HOV E;  3S1N E;  3GTO E;  4KMU E;  4BY7 F;  3S1R E;  4XLP E;  3S2H E;  1SMY E;  1I3Q E;  4BBS E;  4BXX E;  4A3C E;  1WCM E;  1Y1W E;  5C3E F;  3S17 F;  3HOX F;  4LK0 E;  4A3F F;  2PMZ H;  3HOV F;  3GTO F;  3S1Q E;  3S2H F;  3S1N F;  3HOZ E;  5D4C E;  3S1R F;  5M3F E;  3H3V F;  1I3Q F;  2A68 E;  3HKZ H;  3K7A E;  4G7H E;  3HOW E;  1WCM F;  2JA5 E;  2E2H E;  4BBS F;  3GTQ E;  5IP7 E;  3S1Q F;  3CQZ E;  4KN7 E;  3HOZ F;  4Y7N E;  5M3F F;  3K7A F;  5IYD E;  3HOW F;  2JA5 F;  2E2H F;  3GTQ F;  4YFN E;  2NVY E;  5IP7 F;  2YU9 E;  3CQZ F;  2Y0S I;  4OIN E;  3I4N E;  4Y7N F;  2R93 E;  5IYD F;  4A3L E;  3I4M E;  1HQM E; 
#chains in the Genus database with same CATH homology
 2NVY F;  2YU9 F;  3I4N F;  4ZH4 E;  2R93 F;  4LLG E;  2BE5 E;  3I4M F;  2WB1 I;  2R7Z F;  3GTK F;  3FKI F;  2KRX A;  4A3M F;  1TWG F;  2CW0 E;  4XLN E;  3GTG F;  5FJ8 F;  5IYB F;  4G7Z E;  2JA6 F;  4BXX F;  5D4D E;  1Y1W F;  4A3K F;  1TWF F;  3M3Y F;  4LJZ E;  3PO3 F;  2O5J E;  5M3M F;  3HOY F;  5E18 E;  1Y1V F;  3H0G F;  3EQL E;  4Q4Z E;  5TMF E;  5M5W F;  1I6V E;  1I6H F;  4XSX E;  2PPB E;  1ZYR E;  1R9T F;  3H3V G;  4YG2 E;  4YFK E;  2PMZ K;  4C3I F;  2NVX F;  3S2D F;  4A3L F;  3RZO F;  3GTM F;  3HKZ K;  5E17 E;  4OIO E;  2E2J F;  5TMC E;  1YNN K;  3M4O F;  4BBR F;  5D4E E;  2NVQ F;  3GTL F;  1TWH F;  5IYC F;  4G7O E;  4OIP E;  4OIR E;  4C3J F;  2JA8 F;  2B63 F;  1TWC F;  2E2I F;  5FLM F;  3S16 F;  1K83 F;  3S15 F;  4QIW K;  4Y52 F;  4GZY E;  4C2M F;  5C4X F;  2NVT F;  1I50 F;  2A6H E;  5M5X F;  4A3G F;  5IPL E;  3RZD F;  4C3H F;  4A3J F;  2WAQ K;  4YFX E;  4XSZ E;  4MEY E;  2A6E E;  1SFO F;  3S14 F;  5IP9 F;  3WOD E;  3HOU F;  1QKL A;  3GTJ F;  5BYH E;  5C4J F;  4A93 F;  4A3E F;  3GTP F;  4JK1 E;  2R92 F;  4KN4 E;  1IW7 E;  4Q5S E;  2VUM F;  4OIQ E;  4A3D F;  4X6A F;  1TWA F;  5C44 F;  4MEX E;  3DXJ E;  2A69 E;  4LK1 E;  4A3B F;  4AYB K;  2JA7 F;  4MQ9 E;  4A3I F;  5M5Y F;  1YNJ K;  3PO2 F;  2O5I E;  3S1M F;  4BY1 F;  4KMU E;  4BY7 F;  4XLP E;  1SMY E;  5C3E F;  3S17 F;  3HOX F;  4LK0 E;  4A3F F;  3HOV F;  3S1N F;  3GTO F;  5D4C E;  3S1R F;  3S2H F;  4A3C F;  1I3Q F;  2A68 E;  4G7H E;  4BBS F;  1WCM F;  3S1Q F;  4KN7 E;  3HOZ F;  5M3F F;  3K7A F;  3HOW F;  2JA5 F;  2E2H F;  3GTQ F;  4YFN E;  5IP7 F;  3CQZ F;  2Y0S I;  4OIN E;  4Y7N F;  5IYD F;  1HQM E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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