5IYBF

Human core-pic in the open state
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
86
structure length
86
Chain Sequence
GERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 20
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5iybF00
1I6VE 4A3IF 2B63F 3K7AF 3RZDF 5TMCE 4A3DF 1YNNK 1Y1VF 4A3MF 3GTLF 3GTGF 1K83F 4A3BF 5FJ8F 4GZYE 1SMYE 5IYDF 5C3EF 2Y0SI 4A93F 3HOYF 4KN4E 5C4JF 1SFOF 2NVQF 4OIRE 3S14F 1HQME 4XLNE 1WCMF 2E2JF 2A6HE 1ZYRE 4A3KF 3M3YF 2A6EE 3S15F 4Y52F 4MQ9E 3GTKF 2R7ZF 2JA8F 4G7OE 5FLMF 4A3EF 4LJZE 4C3IF 4YFKE 5M5YF 4YG2E 5M5XF 1IW7E 4X6AF 2R93F 3HKZK 4C2MF 3S1RF 3S1QF 5D4EE 4YFNE 3GTPF 2A68E 3GTJF 4JK1E 3HOVF 1YNJK 4XSXE 4OIPE 1R9TF 3PO3F 3CQZF 4BXXF 4Q4ZE 4LK0E 2JA7F 2CW0E 5D4CE 2NVXF 2PMZK 4Y7NF 5E18E 4G7HE 1I6HF 5E17E 2PPBE 3GTMF 3I4MF 3H3VG 5IP9F 4Q5SE 2WB1I 3GTOF 2JA6F 1TWCF 1TWGF 4BBSF 4MEYE 4XSZE 3S2DF 4A3GF 4LK1E 3S16F 4OINE 3HOWF 2WAQK 1TWAF 2O5JE 3S1NF 5D4DE 5TMFE 3S17F 3RZOF 2R92F 5IPLE 3HOXF 5BYHE 3DXJE 4G7ZE 1Y1WF 2NVYF 5M3MF 4YFXE 2E2HF 4A3CF 3PO2F 1I3QF 5M5WF 4MEXE 4ZH4E 2JA5F 4OIQE 4AYBK 3FKIF 2O5IE 3GTQF 3WODE 5IYCF 2A69E 1QKLA 2E2IF 1I50F 3HOUF 1TWFF 3H0GF 3I4NF 3S1MF 4KN7E 4LLGE 4BY1F 4BY7F 5C44F 2YU9F 4KMUE 4BBRF 4OIOE 2VUMF 4C3JF 5C4XF 3M4OF 4XLPE 3S2HF 4A3FF 3HOZF 2NVTF 5IYBF 3EQLE 2BE5E 4A3JF 5IP7F 4A3LF 5M3FF 4C3HF 1TWHF
chains in the Genus database with same CATH superfamily
3RZOE 1I6VE 4A3IF 2B63F 3K7AF 3RZDF 5TMCE 4Y7NE 3I4NF 1Y1WE 4A3DF 1YNNK 1Y1VF 2NVYE 4A3MF 3GTLF 1K83F 3GTGF 5FJ8F 3GTME 4A3BF 4GZYE 3H3VF 1SMYE 4A3CE 3S1NF 4AYBH 5IYDF 5C3EF 2Y0SI 4A93F 1EIKA 3HOYF 1I3QE 4KN4E 5C4JF 1SFOF 2NVQF 4OIRE 3S14F 1HQME 4XLNE 1TWCE 1WCMF 2E2JF 2A6HE 3GTQE 1ZYRE 4A3KF 3M3YF 1TWGE 2A6EE 3I4NE 3S15F 4Y52F 4MQ9E 3GTKF 3S2DE 2R7ZF 3S16E 2JA8F 4G7OE 5FLMF 4A3EF 4LJZE 4C3IF 4YFKE 5M5YF 1TWAE 3S1NE 4YG2E 3S17E 2R92E 5M5XF 3HOZE 1IW7E 3HOXE 4X6AF 5IYBE 2R93F 3HKZK 4C2MF 3S1RF 3S1QF 5D4EE 4YFNE 5IP7E 3HKZH 3GTPF 2A68E 4C3HE 3GTJF 5M3ME 2E2HE 4JK1E 3HOVF 1YNJK 4XSXE 3K7AE 3RZDE 4OIPE 3PO2E 1R9TF 3PO3F 3CQZF 4BXXF 5M5WE 4Q4ZE 4LK0E 1Y1VE 2JA5E 2CW0E 2JA7F 3FKIE 3GTLE 4A3BE 1DZFA 5D4CE 5IYDE 2NVXF 2PMZK 2Y0SH 4Y7NF 5IYCE 5E18E 4G7HE 2E2IE 1I6HF 1I50E 2PPBE 1TWFE 2PMZH 3H0GE 3HOUE 3S1ME 5E17E 3GTMF 3I4MF 4BY1E 4BY7E 5C44E 3H3VG 5IP9F 4A3KE 2YU9E 4Q5SE 2WB1I 4BBRE 2VUME 4C3JE 3GTOF 3S15E 4Y52E 3M4OE 2JA6F 5C4XE 3GTKE 3S2HE 2R7ZE 4A3FE 2NVTE 1TWCF 1TWGF 4BBSF 4A3JE 4A3LE 4MEYE 5M3FE 4XSZE 1TWHE 3S2DF 4A3GF 4LK1E 3S16F 5M5XE 4A3IE 4OINE 2B63E 4X6AE 3HOWF 2R93E 3S1RE 2WAQK 4A3DE 1TWAF 2O5JE 4A3ME 5D4DE 3GTPE 5TMFE 3GTGE 1K83E 2KRXA 2WAQH 5FJ8E 3GTJE 2R92F 3HOXF 3S17F 3RZOF 5IPLE 5BYHE 5C3EE 3DXJE 4A93E 4G7ZE 3HOYE 1Y1WF 3PO3E 5C4JE 1SFOE 4BXXE 2NVQE 2NVYF 3S14E 5M3MF 4YFXE 2E2HF 1WCME 2E2JE 4A3CF 3M3YE 2NVXE 3PO2F 1I3QF 1I6HE 5M5WF 4MEXE 4ZH4E 2JA5F 4OIQE 4AYBK 3FKIF 2JA8E 2O5IE 3GTQF 3I4ME 3WODE 5IP9E 5FLME 4A3EE 2WB1H 4C3IE 2A69E 1QKLA 5M5YE 1I50F 5IYCF 1TWFF 3H0GF 2E2IF 2JA6E 3HOUF 3GTOE 4KN7E 3S1MF 4LLGE 4BY1F 4BY7F 5C44F 4C2ME 4QIWK 2YU9F 3S1QE 4BBSE 4KMUE 4BBRF 4OIOE 2VUMF 4C3JF 5C4XF 4QIWH 3M4OF 4XLPE 3S2HF 4A3FF 3HOZF 4A3GE 2NVTF 5IYBF 3HOVE 3HOWE 3EQLE 2BE5E 4A3JF 1R9TE 3CQZE 5IP7F 4A3LF 5M3FF 4C3HF 2JA7E 1TWHF
chains in the Genus database with same CATH topology
1I6VE 4A3IF 2B63F 3K7AF 3RZDF 5TMCE 4A3DF 1YNNK 1Y1VF 4A3MF 3GTLF 3GTGF 1K83F 4A3BF 5FJ8F 4GZYE 1SMYE 5IYDF 5C3EF 2Y0SI 4A93F 3HOYF 4KN4E 5C4JF 1SFOF 2NVQF 4OIRE 3S14F 1HQME 4XLNE 1WCMF 2E2JF 2A6HE 1ZYRE 4A3KF 3M3YF 2A6EE 3S15F 4Y52F 4MQ9E 3GTKF 2R7ZF 2JA8F 4G7OE 5FLMF 4A3EF 4LJZE 4C3IF 4YFKE 5M5YF 4YG2E 5M5XF 1IW7E 4X6AF 2R93F 3HKZK 4C2MF 3S1RF 3S1QF 5D4EE 4YFNE 3GTPF 2A68E 3GTJF 4JK1E 3HOVF 1YNJK 4XSXE 4OIPE 1R9TF 3PO3F 3CQZF 4BXXF 4Q4ZE 4LK0E 2JA7F 2CW0E 5D4CE 2NVXF 2PMZK 4Y7NF 5E18E 4G7HE 1I6HF 5E17E 2PPBE 3GTMF 3I4MF 3H3VG 5IP9F 4Q5SE 2WB1I 3GTOF 2JA6F 1TWCF 1TWGF 4BBSF 4MEYE 4XSZE 3S2DF 4A3GF 4LK1E 3S16F 4OINE 3HOWF 2WAQK 1TWAF 2O5JE 3S1NF 5D4DE 5TMFE 2KRXA 3S17F 2R92F 3RZOF 5IPLE 3HOXF 5BYHE 3DXJE 4G7ZE 1Y1WF 2NVYF 5M3MF 4YFXE 2E2HF 4A3CF 3PO2F 1I3QF 5M5WF 4MEXE 4ZH4E 2JA5F 4OIQE 4AYBK 3FKIF 2O5IE 3GTQF 3WODE 5IYCF 2A69E 1QKLA 2E2IF 1I50F 3HOUF 1TWFF 3H0GF 3I4NF 3S1MF 4KN7E 4LLGE 4BY1F 4BY7F 5C44F 2YU9F 4QIWK 4KMUE 4BBRF 4OIOE 2VUMF 4C3JF 5C4XF 3M4OF 4XLPE 3S2HF 4A3FF 3HOZF 2NVTF 5IYBF 3EQLE 2BE5E 4A3JF 5IP7F 4A3LF 5M3FF 4C3HF 1TWHF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6V E;  4A3I F;  2B63 F;  3K7A F;  3RZD F;  5TMC E;  4A3D F;  1YNN K;  1Y1V F;  4A3M F;  3GTL F;  3GTG F;  1K83 F;  4A3B F;  5FJ8 F;  4GZY E;  1SMY E;  5IYD F;  5C3E F;  2Y0S I;  4A93 F;  3HOY F;  4KN4 E;  5C4J F;  1SFO F;  2NVQ F;  4OIR E;  3S14 F;  1HQM E;  4XLN E;  1WCM F;  2E2J F;  2A6H E;  1ZYR E;  4A3K F;  3M3Y F;  2A6E E;  3S15 F;  4Y52 F;  4MQ9 E;  3GTK F;  2R7Z F;  2JA8 F;  4G7O E;  5FLM F;  4A3E F;  4LJZ E;  4C3I F;  4YFK E;  5M5Y F;  4YG2 E;  5M5X F;  1IW7 E;  4X6A F;  2R93 F;  3HKZ K;  4C2M F;  3S1R F;  3S1Q F;  5D4E E;  4YFN E;  3GTP F;  2A68 E;  3GTJ F;  4JK1 E;  3HOV F;  1YNJ K;  4XSX E;  4OIP E;  1R9T F;  3PO3 F;  3CQZ F;  4BXX F;  4Q4Z E;  4LK0 E;  2JA7 F;  2CW0 E;  5D4C E;  2NVX F;  2PMZ K;  4Y7N F;  5E18 E;  4G7H E;  1I6H F;  5E17 E;  2PPB E;  3GTM F;  3I4M F;  3H3V G;  5IP9 F;  4Q5S E;  2WB1 I;  3GTO F;  2JA6 F;  1TWC F;  1TWG F;  4BBS F;  4MEY E;  4XSZ E;  3S2D F;  4A3G F;  4LK1 E;  3S16 F;  4OIN E;  3HOW F;  2WAQ K;  1TWA F;  2O5J E;  3S1N F;  5D4D E;  5TMF E;  3S17 F;  3RZO F;  2R92 F;  5IPL E;  3HOX F;  5BYH E;  3DXJ E;  4G7Z E;  1Y1W F;  2NVY F;  5M3M F;  4YFX E;  2E2H F;  4A3C F;  3PO2 F;  1I3Q F;  5M5W F;  4MEX E;  4ZH4 E;  2JA5 F;  4OIQ E;  4AYB K;  3FKI F;  2O5I E;  3GTQ F;  3WOD E;  5IYC F;  2A69 E;  1QKL A;  2E2I F;  1I50 F;  3HOU F;  1TWF F;  3H0G F;  3I4N F;  3S1M F;  4KN7 E;  4LLG E;  4BY1 F;  4BY7 F;  5C44 F;  2YU9 F;  4KMU E;  4BBR F;  4OIO E;  2VUM F;  4C3J F;  5C4X F;  3M4O F;  4XLP E;  3S2H F;  4A3F F;  3HOZ F;  2NVT F;  5IYB F;  3EQL E;  2BE5 E;  4A3J F;  5IP7 F;  4A3L F;  5M3F F;  4C3H F;  1TWH F; 
#chains in the Genus database with same CATH topology
 3RZO E;  1I6V E;  4A3I F;  2B63 F;  3K7A F;  3RZD F;  5TMC E;  4Y7N E;  3I4N F;  1Y1W E;  4A3D F;  1YNN K;  1Y1V F;  2NVY E;  4A3M F;  3GTL F;  1K83 F;  3GTG F;  5FJ8 F;  3GTM E;  4A3B F;  4GZY E;  3H3V F;  1SMY E;  4A3C E;  3S1N F;  4AYB H;  5IYD F;  5C3E F;  2Y0S I;  4A93 F;  1EIK A;  3HOY F;  1I3Q E;  4KN4 E;  5C4J F;  1SFO F;  2NVQ F;  4OIR E;  3S14 F;  1HQM E;  4XLN E;  1TWC E;  1WCM F;  2E2J F;  2A6H E;  3GTQ E;  1ZYR E;  4A3K F;  3M3Y F;  1TWG E;  2A6E E;  3I4N E;  3S15 F;  4Y52 F;  4MQ9 E;  3GTK F;  3S2D E;  2R7Z F;  3S16 E;  2JA8 F;  4G7O E;  5FLM F;  4A3E F;  4LJZ E;  4C3I F;  4YFK E;  5M5Y F;  1TWA E;  3S1N E;  4YG2 E;  3S17 E;  2R92 E;  5M5X F;  3HOZ E;  1IW7 E;  3HOX E;  4X6A F;  5IYB E;  2R93 F;  3HKZ K;  4C2M F;  3S1R F;  3S1Q F;  5D4E E;  4YFN E;  5IP7 E;  3HKZ H;  3GTP F;  2A68 E;  4C3H E;  3GTJ F;  5M3M E;  2E2H E;  4JK1 E;  3HOV F;  1YNJ K;  4XSX E;  3K7A E;  3RZD E;  4OIP E;  3PO2 E;  1R9T F;  3PO3 F;  3CQZ F;  4BXX F;  5M5W E;  4Q4Z E;  4LK0 E;  1Y1V E;  2JA5 E;  2CW0 E;  2JA7 F;  3FKI E;  3GTL E;  4A3B E;  1DZF A;  5D4C E;  5IYD E;  2NVX F;  2PMZ K;  2Y0S H;  4Y7N F;  5IYC E;  5E18 E;  4G7H E;  2E2I E;  1I6H F;  1I50 E;  2PPB E;  1TWF E;  2PMZ H;  3H0G E;  3HOU E;  3S1M E;  5E17 E;  3GTM F;  3I4M F;  4BY1 E;  4BY7 E;  5C44 E;  3H3V G;  5IP9 F;  4A3K E;  2YU9 E;  4Q5S E;  2WB1 I;  4BBR E;  2VUM E;  4C3J E;  3GTO F;  3S15 E;  4Y52 E;  3M4O E;  2JA6 F;  5C4X E;  3GTK E;  3S2H E;  2R7Z E;  4A3F E;  2NVT E;  1TWC F;  1TWG F;  4BBS F;  4A3J E;  4A3L E;  4MEY E;  5M3F E;  4XSZ E;  1TWH E;  3S2D F;  4A3G F;  4LK1 E;  3S16 F;  5M5X E;  4A3I E;  4OIN E;  2B63 E;  4X6A E;  3HOW F;  2R93 E;  3S1R E;  2WAQ K;  4A3D E;  1TWA F;  2O5J E;  4A3M E;  5D4D E;  3GTP E;  5TMF E;  3GTG E;  1K83 E;  2KRX A;  2WAQ H;  5FJ8 E;  3GTJ E;  2R92 F;  3HOX F;  3S17 F;  3RZO F;  5IPL E;  5BYH E;  5C3E E;  3DXJ E;  4A93 E;  4G7Z E;  3HOY E;  1Y1W F;  3PO3 E;  5C4J E;  1SFO E;  4BXX E;  2NVQ E;  2NVY F;  3S14 E;  5M3M F;  4YFX E;  2E2H F;  1WCM E;  2E2J E;  4A3C F;  3M3Y E;  2NVX E;  3PO2 F;  1I3Q F;  1I6H E;  5M5W F;  4MEX E;  4ZH4 E;  2JA5 F;  4OIQ E;  4AYB K;  3FKI F;  2JA8 E;  2O5I E;  3GTQ F;  3I4M E;  3WOD E;  5IP9 E;  5FLM E;  4A3E E;  2WB1 H;  4C3I E;  2A69 E;  1QKL A;  5M5Y E;  1I50 F;  5IYC F;  1TWF F;  3H0G F;  2E2I F;  2JA6 E;  3HOU F;  3GTO E;  4KN7 E;  3S1M F;  4LLG E;  4BY1 F;  4BY7 F;  5C44 F;  4C2M E;  4QIW K;  2YU9 F;  3S1Q E;  4BBS E;  4KMU E;  4BBR F;  4OIO E;  2VUM F;  4C3J F;  5C4X F;  4QIW H;  3M4O F;  4XLP E;  3S2H F;  4A3F F;  3HOZ F;  4A3G E;  2NVT F;  5IYB F;  3HOV E;  3HOW E;  3EQL E;  2BE5 E;  4A3J F;  1R9T E;  3CQZ E;  5IP7 F;  4A3L F;  5M3F F;  4C3H F;  2JA7 E;  1TWH F; 
#chains in the Genus database with same CATH homology
 1I6V E;  4A3I F;  2B63 F;  3K7A F;  3RZD F;  5TMC E;  4A3D F;  1YNN K;  1Y1V F;  4A3M F;  3GTL F;  3GTG F;  1K83 F;  4A3B F;  5FJ8 F;  4GZY E;  1SMY E;  5IYD F;  5C3E F;  2Y0S I;  4A93 F;  3HOY F;  4KN4 E;  5C4J F;  1SFO F;  2NVQ F;  4OIR E;  3S14 F;  1HQM E;  4XLN E;  1WCM F;  2E2J F;  2A6H E;  1ZYR E;  4A3K F;  3M3Y F;  2A6E E;  3S15 F;  4Y52 F;  4MQ9 E;  3GTK F;  2R7Z F;  2JA8 F;  4G7O E;  5FLM F;  4A3E F;  4LJZ E;  4C3I F;  4YFK E;  5M5Y F;  4YG2 E;  5M5X F;  1IW7 E;  4X6A F;  2R93 F;  3HKZ K;  4C2M F;  3S1R F;  3S1Q F;  5D4E E;  4YFN E;  3GTP F;  2A68 E;  3GTJ F;  4JK1 E;  3HOV F;  1YNJ K;  4XSX E;  4OIP E;  1R9T F;  3PO3 F;  3CQZ F;  4BXX F;  4Q4Z E;  4LK0 E;  2JA7 F;  2CW0 E;  5D4C E;  2NVX F;  2PMZ K;  4Y7N F;  5E18 E;  4G7H E;  1I6H F;  5E17 E;  2PPB E;  3GTM F;  3I4M F;  3H3V G;  5IP9 F;  4Q5S E;  2WB1 I;  3GTO F;  2JA6 F;  1TWC F;  1TWG F;  4BBS F;  4MEY E;  4XSZ E;  3S2D F;  4A3G F;  4LK1 E;  3S16 F;  4OIN E;  3HOW F;  2WAQ K;  1TWA F;  2O5J E;  3S1N F;  5D4D E;  5TMF E;  2KRX A;  3S17 F;  2R92 F;  3RZO F;  5IPL E;  3HOX F;  5BYH E;  3DXJ E;  4G7Z E;  1Y1W F;  2NVY F;  5M3M F;  4YFX E;  2E2H F;  4A3C F;  3PO2 F;  1I3Q F;  5M5W F;  4MEX E;  4ZH4 E;  2JA5 F;  4OIQ E;  4AYB K;  3FKI F;  2O5I E;  3GTQ F;  3WOD E;  5IYC F;  2A69 E;  1QKL A;  2E2I F;  1I50 F;  3HOU F;  1TWF F;  3H0G F;  3I4N F;  3S1M F;  4KN7 E;  4LLG E;  4BY1 F;  4BY7 F;  5C44 F;  2YU9 F;  4QIW K;  4KMU E;  4BBR F;  4OIO E;  2VUM F;  4C3J F;  5C4X F;  3M4O F;  4XLP E;  3S2H F;  4A3F F;  3HOZ F;  2NVT F;  5IYB F;  3EQL E;  2BE5 E;  4A3J F;  5IP7 F;  4A3L F;  5M3F F;  4C3H F;  1TWH F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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