5IYCF

Human core-pic in the initial transcribing state
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
86
structure length
86
Chain Sequence
GERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 22
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5iycF00
1YNJK 1WCMF 1K83F 3WODE 1I6HF 3RZOF 4LK0E 4OIRE 3GTOF 5FJ8F 4KN4E 4OIPE 5IYDF 1Y1VF 3GTPF 2E2JF 4A3KF 4JK1E 4KN7E 3S15F 4YFXE 4Y7NF 2NVYF 4A3FF 4GZYE 2JA7F 5E17E 3H3VG 3PO3F 4A3IF 3S14F 4AYBK 4C2MF 3GTJF 2JA5F 4A3GF 4A3CF 4A3LF 1YNNK 3GTMF 2CW0E 5IPLE 2JA8F 1TWGF 1SFOF 1I3QF 2A6EE 1TWAF 2R92F 4MQ9E 4XSXE 5D4DE 2E2IF 5TMFE 5C44F 4C3HF 2BE5E 3H0GF 4LK1E 4XLNE 5IP9F 4G7ZE 2B63F 3HKZK 2YU9F 5IYBF 2Y0SI 2JA6F 5M5YF 2E2HF 4Q4ZE 4MEYE 4XSZE 3CQZF 3S1NF 3S16F 3HOXF 3S2DF 4BBRF 4OIQE 4A93F 1IW7E 3I4NF 4LLGE 2A69E 5M3FF 3HOYF 2VUMF 4A3EF 3HOVF 5M3MF 3S1MF 4YG2E 2NVTF 2A68E 4OINE 3S1RF 1TWCF 4Y52F 1SMYE 3M4OF 3FKIF 4ZH4E 4YFNE 5TMCE 4A3JF 1Y1WF 4G7OE 3GTKF 3M3YF 2WAQK 5IP7F 5BYHE 4C3JF 4XLPE 1QKLA 2R93F 5C3EF 1HQME 3EQLE 3HOUF 3GTGF 4BBSF 3S1QF 4X6AF 3PO2F 4LJZE 3GTLF 3S2HF 3I4MF 5M5XF 2NVQF 1I6VE 2A6HE 3S17F 2R7ZF 2WB1I 4MEXE 2NVXF 3DXJE 1I50F 3RZDF 3HOZF 2O5JE 4A3BF 5C4JF 1R9TF 3K7AF 2O5IE 1ZYRE 4G7HE 4A3DF 5C4XF 5E18E 2PMZK 4KMUE 4BY1F 2PPBE 4BY7F 1TWFF 5FLMF 3GTQF 4BXXF 1TWHF 4A3MF 4OIOE 5M5WF 5D4EE 4YFKE 4Q5SE 3HOWF 5IYCF 5D4CE 4C3IF
chains in the Genus database with same CATH superfamily
1YNJK 1WCMF 3S1RE 1K83F 3WODE 1I6HF 4BY1E 4LK0E 4OIRE 3RZOF 3HKZH 5FJ8F 3GTOF 4KN4E 1TWFE 1Y1WE 4OIPE 5IYDF 5FLME 3GTQE 1Y1VF 3M3YE 3GTPF 1TWHE 2E2JF 4A3ME 3H3VF 4A3KF 4JK1E 4KN7E 3S15F 5C3EE 4YFXE 4Y7NF 5IYCE 2NVYF 4QIWH 4A3FF 2JA7F 4BBSE 3H3VG 3PO3F 4GZYE 4A3IF 3S14F 5E17E 1WCME 1I6HE 3RZOE 1EIKA 4AYBK 4C2MF 3GTJF 2JA5F 2NVQE 3GTOE 5FJ8E 4A3CF 4A3GF 4A3LF 1YNNK 3GTMF 2CW0E 5IYDE 5IPLE 2JA8F 1Y1VE 1TWGF 3RZDE 3HOZE 1SFOF 1I3QF 3GTPE 4QIWK 2A6EE 4A3KE 1TWAF 3S15E 2R92F 4MQ9E 2NVYE 4XSXE 5D4DE 2JA7E 2E2IF 4A3IE 5TMFE 5C44F 4C3HF 2BE5E 3H0GF 2JA5E 4A3GE 4LK1E 4XLNE 4A3CE 4BY7E 4A3LE 2WAQH 5IP9F 4G7ZE 2B63F 3GTME 4BXXE 2JA8E 1TWGE 5M5WE 1I3QE 1DZFA 2WB1H 1TWAE 3HOWE 3HKZK 2YU9F 2R92E 4C3IE 5IYBF 2Y0SI 2JA6F 1K83E 5M5YF 2E2HF 5C44E 4Q4ZE 4MEYE 3H0GE 4XSZE 4C3HE 3CQZF 3S1NF 5IP9E 3HOXF 2B63E 4BBRF 3S16F 3S2DF 4OIQE 4A93F 2E2JE 1IW7E 3I4NF 4LLGE 2A69E 4Y7NE 5M3FF 3HOYF 2YU9E 4A3FE 2VUMF 4A3EF 3PO3E 3S14E 2JA6E 3HOVF 5M3MF 5M5YE 3S1MF 4C2ME 3GTJE 2E2HE 4YG2E 2NVTF 3CQZE 2A68E 4OINE 3S1NE 3S16E 3HOXE 4BBRE 3S1RF 1TWCF 1SFOE 4Y52F 4A93E 1SMYE 3M4OF 3FKIF 4ZH4E 4YFNE 5TMCE 4A3JF 3I4NE 1Y1WF 4G7OE 5M3FE 3HOYE 3GTKF 2KRXA 2VUME 3M3YF 4A3EE 2WAQK 5IP7F 2E2IE 5BYHE 4C3JF 5M3ME 3S1ME 4XLPE 1QKLA 2R93F 5C3EF 1HQME 3EQLE 3HOUF 2NVTE 3GTGF 4BBSF 3S1QF 4X6AF 3PO2F 4LJZE 3GTLF 3S2HF 3I4MF 1TWCE 5M5XF 4Y52E 2NVQF 3M4OE 1I6VE 2A6HE 3FKIE 2R7ZF 2PMZH 3S17F 2WB1I 4A3JE 4MEXE 2NVXF 5C4XE 3DXJE 4AYBH 5IYBE 1I50F 3RZDF 3GTKE 3HOZF 2O5JE 5IP7E 4A3BF 4C3JE 5C4JF 1R9TF 3K7AF 2O5IE 1ZYRE 4G7HE 4A3DF 2R93E 5C4XF 3HOUE 3S2DE 5E18E 2PMZK 3GTGE 3S1QE 4X6AE 3PO2E 4KMUE 4BY1F 3GTLE 2PPBE 3I4ME 3S2HE 5M5XE 3S17E 4BY7F 2R7ZE 1TWFF 5FLMF 3GTQF 2NVXE 4BXXF 1TWHF 1I50E 4A3MF 5M5WF 4OIOE 3HOVE 5D4EE 4A3BE 4YFKE 4Q5SE 5C4JE 1R9TE 3K7AE 5IYCF 2Y0SH 3HOWF 4A3DE 5D4CE 4C3IF
chains in the Genus database with same CATH topology
1YNJK 1WCMF 1K83F 3WODE 1I6HF 3RZOF 4LK0E 4OIRE 3GTOF 5FJ8F 4KN4E 4OIPE 5IYDF 1Y1VF 3GTPF 2E2JF 4A3KF 4JK1E 4KN7E 3S15F 4YFXE 4Y7NF 2NVYF 4A3FF 4GZYE 2JA7F 5E17E 3H3VG 3PO3F 4A3IF 3S14F 4AYBK 4C2MF 3GTJF 2JA5F 4A3GF 4A3CF 4A3LF 1YNNK 3GTMF 2CW0E 5IPLE 2JA8F 1TWGF 1SFOF 1I3QF 4QIWK 2A6EE 1TWAF 2R92F 4MQ9E 4XSXE 5D4DE 2E2IF 5TMFE 5C44F 4C3HF 2BE5E 3H0GF 4LK1E 4XLNE 5IP9F 4G7ZE 2B63F 3HKZK 2YU9F 5IYBF 2Y0SI 2JA6F 5M5YF 2E2HF 4Q4ZE 4MEYE 4XSZE 3CQZF 3S1NF 3S16F 3HOXF 3S2DF 4BBRF 4OIQE 4A93F 1IW7E 3I4NF 4LLGE 2A69E 5M3FF 3HOYF 2VUMF 4A3EF 3HOVF 5M3MF 3S1MF 4YG2E 2NVTF 2A68E 4OINE 3S1RF 1TWCF 4Y52F 1SMYE 3M4OF 3FKIF 4ZH4E 4YFNE 5TMCE 4A3JF 1Y1WF 4G7OE 3GTKF 2KRXA 3M3YF 2WAQK 5IP7F 5BYHE 4C3JF 4XLPE 1QKLA 2R93F 5C3EF 1HQME 3EQLE 3HOUF 3GTGF 4BBSF 3S1QF 4X6AF 3PO2F 4LJZE 3GTLF 3S2HF 3I4MF 5M5XF 2NVQF 1I6VE 2A6HE 3S17F 2R7ZF 2WB1I 4MEXE 2NVXF 3DXJE 1I50F 3RZDF 3HOZF 2O5JE 4A3BF 5C4JF 1R9TF 3K7AF 2O5IE 1ZYRE 4G7HE 4A3DF 5C4XF 5E18E 2PMZK 4KMUE 4BY1F 2PPBE 4BY7F 1TWFF 5FLMF 3GTQF 4BXXF 1TWHF 4A3MF 4OIOE 5M5WF 5D4EE 4YFKE 4Q5SE 3HOWF 5IYCF 5D4CE 4C3IF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YNJ K;  1WCM F;  1K83 F;  3WOD E;  1I6H F;  3RZO F;  4LK0 E;  4OIR E;  3GTO F;  5FJ8 F;  4KN4 E;  4OIP E;  5IYD F;  1Y1V F;  3GTP F;  2E2J F;  4A3K F;  4JK1 E;  4KN7 E;  3S15 F;  4YFX E;  4Y7N F;  2NVY F;  4A3F F;  4GZY E;  2JA7 F;  5E17 E;  3H3V G;  3PO3 F;  4A3I F;  3S14 F;  4AYB K;  4C2M F;  3GTJ F;  2JA5 F;  4A3G F;  4A3C F;  4A3L F;  1YNN K;  3GTM F;  2CW0 E;  5IPL E;  2JA8 F;  1TWG F;  1SFO F;  1I3Q F;  2A6E E;  1TWA F;  2R92 F;  4MQ9 E;  4XSX E;  5D4D E;  2E2I F;  5TMF E;  5C44 F;  4C3H F;  2BE5 E;  3H0G F;  4LK1 E;  4XLN E;  5IP9 F;  4G7Z E;  2B63 F;  3HKZ K;  2YU9 F;  5IYB F;  2Y0S I;  2JA6 F;  5M5Y F;  2E2H F;  4Q4Z E;  4MEY E;  4XSZ E;  3CQZ F;  3S1N F;  3S16 F;  3HOX F;  3S2D F;  4BBR F;  4OIQ E;  4A93 F;  1IW7 E;  3I4N F;  4LLG E;  2A69 E;  5M3F F;  3HOY F;  2VUM F;  4A3E F;  3HOV F;  5M3M F;  3S1M F;  4YG2 E;  2NVT F;  2A68 E;  4OIN E;  3S1R F;  1TWC F;  4Y52 F;  1SMY E;  3M4O F;  3FKI F;  4ZH4 E;  4YFN E;  5TMC E;  4A3J F;  1Y1W F;  4G7O E;  3GTK F;  3M3Y F;  2WAQ K;  5IP7 F;  5BYH E;  4C3J F;  4XLP E;  1QKL A;  2R93 F;  5C3E F;  1HQM E;  3EQL E;  3HOU F;  3GTG F;  4BBS F;  3S1Q F;  4X6A F;  3PO2 F;  4LJZ E;  3GTL F;  3S2H F;  3I4M F;  5M5X F;  2NVQ F;  1I6V E;  2A6H E;  3S17 F;  2R7Z F;  2WB1 I;  4MEX E;  2NVX F;  3DXJ E;  1I50 F;  3RZD F;  3HOZ F;  2O5J E;  4A3B F;  5C4J F;  1R9T F;  3K7A F;  2O5I E;  1ZYR E;  4G7H E;  4A3D F;  5C4X F;  5E18 E;  2PMZ K;  4KMU E;  4BY1 F;  2PPB E;  4BY7 F;  1TWF F;  5FLM F;  3GTQ F;  4BXX F;  1TWH F;  4A3M F;  4OIO E;  5M5W F;  5D4E E;  4YFK E;  4Q5S E;  3HOW F;  5IYC F;  5D4C E;  4C3I F; 
#chains in the Genus database with same CATH topology
 1YNJ K;  1WCM F;  3S1R E;  1K83 F;  3WOD E;  1I6H F;  4BY1 E;  4LK0 E;  4OIR E;  3RZO F;  3HKZ H;  5FJ8 F;  3GTO F;  4KN4 E;  1TWF E;  1Y1W E;  4OIP E;  5IYD F;  5FLM E;  3GTQ E;  1Y1V F;  3M3Y E;  3GTP F;  1TWH E;  2E2J F;  4A3M E;  3H3V F;  4A3K F;  4JK1 E;  4KN7 E;  3S15 F;  5C3E E;  4YFX E;  4Y7N F;  5IYC E;  2NVY F;  4QIW H;  4A3F F;  2JA7 F;  4BBS E;  3H3V G;  3PO3 F;  4GZY E;  4A3I F;  3S14 F;  5E17 E;  1WCM E;  1I6H E;  3RZO E;  1EIK A;  4AYB K;  4C2M F;  3GTJ F;  2JA5 F;  2NVQ E;  3GTO E;  5FJ8 E;  4A3C F;  4A3G F;  4A3L F;  1YNN K;  3GTM F;  2CW0 E;  5IYD E;  5IPL E;  2JA8 F;  1Y1V E;  1TWG F;  3RZD E;  3HOZ E;  1SFO F;  1I3Q F;  3GTP E;  4QIW K;  2A6E E;  4A3K E;  1TWA F;  3S15 E;  2R92 F;  4MQ9 E;  2NVY E;  4XSX E;  5D4D E;  2JA7 E;  2E2I F;  4A3I E;  5TMF E;  5C44 F;  4C3H F;  2BE5 E;  3H0G F;  2JA5 E;  4A3G E;  4LK1 E;  4XLN E;  4A3C E;  4BY7 E;  4A3L E;  2WAQ H;  5IP9 F;  4G7Z E;  2B63 F;  3GTM E;  4BXX E;  2JA8 E;  1TWG E;  5M5W E;  1I3Q E;  1DZF A;  2WB1 H;  1TWA E;  3HOW E;  3HKZ K;  2YU9 F;  2R92 E;  4C3I E;  5IYB F;  2Y0S I;  2JA6 F;  1K83 E;  5M5Y F;  2E2H F;  5C44 E;  4Q4Z E;  4MEY E;  3H0G E;  4XSZ E;  4C3H E;  3CQZ F;  3S1N F;  5IP9 E;  3HOX F;  2B63 E;  4BBR F;  3S16 F;  3S2D F;  4OIQ E;  4A93 F;  2E2J E;  1IW7 E;  3I4N F;  4LLG E;  2A69 E;  4Y7N E;  5M3F F;  3HOY F;  2YU9 E;  4A3F E;  2VUM F;  4A3E F;  3PO3 E;  3S14 E;  2JA6 E;  3HOV F;  5M3M F;  5M5Y E;  3S1M F;  4C2M E;  3GTJ E;  2E2H E;  4YG2 E;  2NVT F;  3CQZ E;  2A68 E;  4OIN E;  3S1N E;  3S16 E;  3HOX E;  4BBR E;  3S1R F;  1TWC F;  1SFO E;  4Y52 F;  4A93 E;  1SMY E;  3M4O F;  3FKI F;  4ZH4 E;  4YFN E;  5TMC E;  4A3J F;  3I4N E;  1Y1W F;  4G7O E;  5M3F E;  3HOY E;  3GTK F;  2KRX A;  2VUM E;  3M3Y F;  4A3E E;  2WAQ K;  5IP7 F;  2E2I E;  5BYH E;  4C3J F;  5M3M E;  3S1M E;  4XLP E;  1QKL A;  2R93 F;  5C3E F;  1HQM E;  3EQL E;  3HOU F;  2NVT E;  3GTG F;  4BBS F;  3S1Q F;  4X6A F;  3PO2 F;  4LJZ E;  3GTL F;  3S2H F;  3I4M F;  1TWC E;  5M5X F;  4Y52 E;  2NVQ F;  3M4O E;  1I6V E;  2A6H E;  3FKI E;  2R7Z F;  2PMZ H;  3S17 F;  2WB1 I;  4A3J E;  4MEX E;  2NVX F;  5C4X E;  3DXJ E;  4AYB H;  5IYB E;  1I50 F;  3RZD F;  3GTK E;  3HOZ F;  2O5J E;  5IP7 E;  4A3B F;  4C3J E;  5C4J F;  1R9T F;  3K7A F;  2O5I E;  1ZYR E;  4G7H E;  4A3D F;  2R93 E;  5C4X F;  3HOU E;  3S2D E;  5E18 E;  2PMZ K;  3GTG E;  3S1Q E;  4X6A E;  3PO2 E;  4KMU E;  4BY1 F;  3GTL E;  2PPB E;  3I4M E;  3S2H E;  5M5X E;  3S17 E;  4BY7 F;  2R7Z E;  1TWF F;  5FLM F;  3GTQ F;  2NVX E;  4BXX F;  1TWH F;  1I50 E;  4A3M F;  5M5W F;  4OIO E;  3HOV E;  5D4E E;  4A3B E;  4YFK E;  4Q5S E;  5C4J E;  1R9T E;  3K7A E;  5IYC F;  2Y0S H;  3HOW F;  4A3D E;  5D4C E;  4C3I F; 
#chains in the Genus database with same CATH homology
 1YNJ K;  1WCM F;  1K83 F;  3WOD E;  1I6H F;  3RZO F;  4LK0 E;  4OIR E;  3GTO F;  5FJ8 F;  4KN4 E;  4OIP E;  5IYD F;  1Y1V F;  3GTP F;  2E2J F;  4A3K F;  4JK1 E;  4KN7 E;  3S15 F;  4YFX E;  4Y7N F;  2NVY F;  4A3F F;  4GZY E;  2JA7 F;  5E17 E;  3H3V G;  3PO3 F;  4A3I F;  3S14 F;  4AYB K;  4C2M F;  3GTJ F;  2JA5 F;  4A3G F;  4A3C F;  4A3L F;  1YNN K;  3GTM F;  2CW0 E;  5IPL E;  2JA8 F;  1TWG F;  1SFO F;  1I3Q F;  4QIW K;  2A6E E;  1TWA F;  2R92 F;  4MQ9 E;  4XSX E;  5D4D E;  2E2I F;  5TMF E;  5C44 F;  4C3H F;  2BE5 E;  3H0G F;  4LK1 E;  4XLN E;  5IP9 F;  4G7Z E;  2B63 F;  3HKZ K;  2YU9 F;  5IYB F;  2Y0S I;  2JA6 F;  5M5Y F;  2E2H F;  4Q4Z E;  4MEY E;  4XSZ E;  3CQZ F;  3S1N F;  3S16 F;  3HOX F;  3S2D F;  4BBR F;  4OIQ E;  4A93 F;  1IW7 E;  3I4N F;  4LLG E;  2A69 E;  5M3F F;  3HOY F;  2VUM F;  4A3E F;  3HOV F;  5M3M F;  3S1M F;  4YG2 E;  2NVT F;  2A68 E;  4OIN E;  3S1R F;  1TWC F;  4Y52 F;  1SMY E;  3M4O F;  3FKI F;  4ZH4 E;  4YFN E;  5TMC E;  4A3J F;  1Y1W F;  4G7O E;  3GTK F;  2KRX A;  3M3Y F;  2WAQ K;  5IP7 F;  5BYH E;  4C3J F;  4XLP E;  1QKL A;  2R93 F;  5C3E F;  1HQM E;  3EQL E;  3HOU F;  3GTG F;  4BBS F;  3S1Q F;  4X6A F;  3PO2 F;  4LJZ E;  3GTL F;  3S2H F;  3I4M F;  5M5X F;  2NVQ F;  1I6V E;  2A6H E;  3S17 F;  2R7Z F;  2WB1 I;  4MEX E;  2NVX F;  3DXJ E;  1I50 F;  3RZD F;  3HOZ F;  2O5J E;  4A3B F;  5C4J F;  1R9T F;  3K7A F;  2O5I E;  1ZYR E;  4G7H E;  4A3D F;  5C4X F;  5E18 E;  2PMZ K;  4KMU E;  4BY1 F;  2PPB E;  4BY7 F;  1TWF F;  5FLM F;  3GTQ F;  4BXX F;  1TWH F;  4A3M F;  4OIO E;  5M5W F;  5D4E E;  4YFK E;  4Q5S E;  3HOW F;  5IYC F;  5D4C E;  4C3I F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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