5IYDF

Human core-pic in the initial transcribing state (no iis)
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
86
structure length
86
Chain Sequence
GERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna/rna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 19
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5iydF00
5M5WF 5C4JF 3GTPF 1SMYE 3I4NF 4MEYE 4YFNE 3S1QF 1YNNK 4OIPE 3PO2F 4BY1F 2E2IF 3FKIF 4X6AF 2A68E 4LJZE 2B63F 4XSXE 4G7OE 2NVTF 2VUMF 3GTJF 5M5XF 4YG2E 3RZOF 4GZYE 4LLGE 4XLNE 2BE5E 3EQLE 4A3LF 3RZDF 4G7ZE 4OIOE 1QKLA 3M4OF 2A69E 5D4EE 1SFOF 1Y1VF 2E2JF 2O5IE 2O5JE 2E2HF 3GTMF 1I50F 1WCMF 5D4CE 5IYBF 4XLPE 2NVXF 3HOVF 3I4MF 4OIQE 3S16F 4BBRF 4C3IF 3S1RF 4A3GF 3S1NF 1I3QF 4LK1E 1TWFF 2Y0SI 5C3EF 3HOWF 5IP9F 5M3FF 2JA7F 4YFXE 4AYBK 2NVQF 4KN7E 3GTGF 2PPBE 4Q5SE 2R92F 4XSZE 4A3KF 3S2DF 5IPLE 3HOUF 1TWGF 4A93F 1ZYRE 4MQ9E 3GTKF 3HOZF 5FLMF 3GTQF 1K83F 3S14F 4Y52F 2A6EE 5TMFE 5IP7F 3S2HF 4BY7F 4OINE 4KN4E 5BYHE 2R7ZF 4BBSF 2WAQK 4C3JF 3H0GF 1I6HF 3S15F 1TWAF 2JA6F 5C44F 4Y7NF 3HOYF 3PO3F 1Y1WF 3CQZF 4C2MF 5M5YF 5IYDF 4Q4ZE 4YFKE 3WODE 2NVYF 1TWCF 3GTLF 5M3MF 3DXJE 4KMUE 3M3YF 2WB1I 1HQME 2JA8F 1YNJK 1TWHF 2JA5F 4A3CF 5TMCE 2R93F 5D4DE 1R9TF 4C3HF 1I6VE 4JK1E 4G7HE 5E18E 4BXXF 4A3FF 3HKZK 4A3EF 4A3MF 3GTOF 4A3DF 2PMZK 2YU9F 4A3JF 3S17F 5C4XF 3S1MF 3H3VG 1IW7E 4MEXE 4OIRE 5E17E 2A6HE 3HOXF 5IYCF 5FJ8F 4LK0E 4A3IF 3K7AF 2CW0E 4A3BF 4ZH4E
chains in the Genus database with same CATH superfamily
5M5WF 3GTJE 2R92E 5M5XE 5C4JF 3GTPF 1SMYE 3S2DE 3I4NF 4MEYE 4YFNE 5FLME 3S1QF 1YNNK 4OIPE 3PO2F 4BY1F 1K83E 2E2IF 2E2JE 3S14E 1DZFA 4Y52E 3FKIF 4X6AF 2A68E 1I50E 3GTME 5IP7E 4LJZE 2B63F 4BY7E 4QIWK 4XSXE 4G7OE 2NVTF 2VUMF 2Y0SH 3GTJF 5M5XF 4YG2E 3RZOF 4GZYE 4LLGE 4XLNE 2BE5E 4C3JE 3H0GE 3EQLE 4A3LF 1I6HE 3RZDF 3S1RE 3S15E 4G7ZE 1I3QE 5C3EE 4OIOE 1QKLA 5C44E 2A69E 5D4EE 1SFOF 1Y1VF 2E2JF 2JA6E 2JA7E 2E2HF 2O5IE 4Y7NE 3HOYE 5IPLE 1Y1WE 1I50F 2NVQE 3GTMF 3GTGE 5M5YE 1WCMF 5IYDE 2KRXA 5D4CE 4A3KE 3HOUE 1TWGE 4A93E 5IYBF 4XLPE 3GTKE 2NVXF 3HOZE 3HOVF 3I4MF 3GTQE 1TWCE 4OIQE 5M3ME 3S16F 4BBRF 4C3IF 3S1RF 3M3YE 3S1NF 4A3GF 1EIKA 1I3QF 4LK1E 1TWFF 2Y0SI 5C3EF 3HOWF 3M4OF 5IP9F 5M3FF 2JA7F 4YFXE 3S2HE 4AYBK 2NVQF 4KN7E 2JA5E 4A3CE 3GTGF 2PPBE 2R93E 4Q5SE 2R92F 4XSZE 4A3KF 1R9TE 4C3HE 2R7ZE 3HOUF 3S2DF 1TWGF 4A93F 1ZYRE 4BBSE 4MQ9E 3GTKF 3HOZF 3H3VF 4A3FE 5FLMF 4BXXE 3GTQF 3GTOE 1TWAE 4A3DE 2YU9E 4A3JE 1K83F 3S17E 5C4XE 3S14F 4Y52F 2A6EE 3S1ME 3PO3E 5TMFE 3CQZE 4AYBH 5IP7F 4C2ME 3S2HF 4BY7F 4OINE 4KN4E 5BYHE 2WB1H 2NVYE 2R7ZF 5IYCE 5FJ8E 4BBSF 4A3IE 2WAQK 3K7AE 4C3JF 3H0GF 3GTLE 1I6HF 4A3BE 3S15F 5M5WE 1TWAF 5C4JE 2JA6F 5C44F 2JA8E 3I4NE 4Y7NF 3HOYF 3PO3F 1Y1WF 3CQZF 1TWHE 4C2MF 4BY1E 3PO2E 5M5YF 5IYDF 4Q4ZE 2E2IE 2O5JE 4YFKE 3WODE 2NVYF 4X6AE 2WAQH 4A3EE 4A3ME 1TWCF 3GTLF 5M3MF 3DXJE 4KMUE 2NVTE 2VUME 3M3YF 2PMZH 2WB1I 1HQME 3RZOE 2JA8F 1YNJK 4A3LE 3RZDE 1TWHF 2JA5F 4A3CF 5TMCE 3M4OE 2R93F 1SFOE 1Y1VE 5D4DE 3HOXE 1R9TF 2E2HE 4C3HF 1I6VE 4JK1E 4G7HE 5E18E 4BXXF 4A3FF 3HKZK 4A3EF 1WCME 4A3MF 3GTOF 4A3DF 3GTPE 2PMZK 2YU9F 4A3JF 3S17F 5C4XF 5IYBE 3S1MF 2NVXE 3H3VG 3HOVE 3I4ME 3S1QE 3S16E 4BBRE 4C3IE 4A3GE 3S1NE 3HOWE 1IW7E 1TWFE 4MEXE 3FKIE 5IP9E 5M3FE 2A6HE 3HOXF 4OIRE 5IYCF 5FJ8F 5E17E 2B63E 4LK0E 4A3IF 3K7AF 3HKZH 2CW0E 4QIWH 4A3BF 4ZH4E
chains in the Genus database with same CATH topology
5M5WF 5C4JF 3GTPF 1SMYE 3I4NF 4MEYE 4YFNE 3S1QF 1YNNK 4OIPE 3PO2F 4BY1F 2E2IF 3FKIF 4X6AF 2A68E 4LJZE 2B63F 4QIWK 4XSXE 4G7OE 2NVTF 2VUMF 3GTJF 5M5XF 4YG2E 3RZOF 4GZYE 4LLGE 4XLNE 2BE5E 3EQLE 4A3LF 3RZDF 4G7ZE 4OIOE 1QKLA 3M4OF 2A69E 5D4EE 1SFOF 1Y1VF 2E2JF 2O5IE 2O5JE 2E2HF 3GTMF 1I50F 1WCMF 2KRXA 5D4CE 5IYBF 4XLPE 2NVXF 3HOVF 3I4MF 4OIQE 3S16F 4BBRF 4C3IF 3S1RF 4A3GF 3S1NF 1I3QF 4LK1E 1TWFF 2Y0SI 5C3EF 3HOWF 5IP9F 5M3FF 2JA7F 4YFXE 4AYBK 2NVQF 4KN7E 3GTGF 2PPBE 4Q5SE 2R92F 4XSZE 4A3KF 3S2DF 5IPLE 3HOUF 1TWGF 4A93F 1ZYRE 4MQ9E 3GTKF 3HOZF 5FLMF 3GTQF 1K83F 3S14F 4Y52F 2A6EE 5TMFE 5IP7F 3S2HF 4BY7F 4OINE 4KN4E 5BYHE 2R7ZF 4BBSF 2WAQK 4C3JF 3H0GF 1I6HF 3S15F 1TWAF 2JA6F 5C44F 4Y7NF 3HOYF 3PO3F 1Y1WF 3CQZF 4C2MF 5M5YF 5IYDF 4Q4ZE 4YFKE 3WODE 2NVYF 1TWCF 3GTLF 5M3MF 3DXJE 4KMUE 3M3YF 2WB1I 1HQME 2JA8F 1YNJK 1TWHF 2JA5F 4A3CF 5TMCE 2R93F 5D4DE 1R9TF 4C3HF 1I6VE 4JK1E 4G7HE 5E18E 4BXXF 4A3FF 3HKZK 4A3EF 4A3MF 3GTOF 4A3DF 2PMZK 2YU9F 4A3JF 3S17F 5C4XF 3S1MF 3H3VG 1IW7E 4MEXE 4OIRE 5E17E 2A6HE 3HOXF 5IYCF 5FJ8F 4LK0E 4A3IF 3K7AF 2CW0E 4A3BF 4ZH4E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M5W F;  5C4J F;  3GTP F;  1SMY E;  3I4N F;  4MEY E;  4YFN E;  3S1Q F;  1YNN K;  4OIP E;  3PO2 F;  4BY1 F;  2E2I F;  3FKI F;  4X6A F;  2A68 E;  4LJZ E;  2B63 F;  4XSX E;  4G7O E;  2NVT F;  2VUM F;  3GTJ F;  5M5X F;  4YG2 E;  3RZO F;  4GZY E;  4LLG E;  4XLN E;  2BE5 E;  3EQL E;  4A3L F;  3RZD F;  4G7Z E;  4OIO E;  1QKL A;  3M4O F;  2A69 E;  5D4E E;  1SFO F;  1Y1V F;  2E2J F;  2O5I E;  2O5J E;  2E2H F;  3GTM F;  1I50 F;  1WCM F;  5D4C E;  5IYB F;  4XLP E;  2NVX F;  3HOV F;  3I4M F;  4OIQ E;  3S16 F;  4BBR F;  4C3I F;  3S1R F;  4A3G F;  3S1N F;  1I3Q F;  4LK1 E;  1TWF F;  2Y0S I;  5C3E F;  3HOW F;  5IP9 F;  5M3F F;  2JA7 F;  4YFX E;  4AYB K;  2NVQ F;  4KN7 E;  3GTG F;  2PPB E;  4Q5S E;  2R92 F;  4XSZ E;  4A3K F;  3S2D F;  5IPL E;  3HOU F;  1TWG F;  4A93 F;  1ZYR E;  4MQ9 E;  3GTK F;  3HOZ F;  5FLM F;  3GTQ F;  1K83 F;  3S14 F;  4Y52 F;  2A6E E;  5TMF E;  5IP7 F;  3S2H F;  4BY7 F;  4OIN E;  4KN4 E;  5BYH E;  2R7Z F;  4BBS F;  2WAQ K;  4C3J F;  3H0G F;  1I6H F;  3S15 F;  1TWA F;  2JA6 F;  5C44 F;  4Y7N F;  3HOY F;  3PO3 F;  1Y1W F;  3CQZ F;  4C2M F;  5M5Y F;  5IYD F;  4Q4Z E;  4YFK E;  3WOD E;  2NVY F;  1TWC F;  3GTL F;  5M3M F;  3DXJ E;  4KMU E;  3M3Y F;  2WB1 I;  1HQM E;  2JA8 F;  1YNJ K;  1TWH F;  2JA5 F;  4A3C F;  5TMC E;  2R93 F;  5D4D E;  1R9T F;  4C3H F;  1I6V E;  4JK1 E;  4G7H E;  5E18 E;  4BXX F;  4A3F F;  3HKZ K;  4A3E F;  4A3M F;  3GTO F;  4A3D F;  2PMZ K;  2YU9 F;  4A3J F;  3S17 F;  5C4X F;  3S1M F;  3H3V G;  1IW7 E;  4MEX E;  4OIR E;  5E17 E;  2A6H E;  3HOX F;  5IYC F;  5FJ8 F;  4LK0 E;  4A3I F;  3K7A F;  2CW0 E;  4A3B F;  4ZH4 E; 
#chains in the Genus database with same CATH topology
 5M5W F;  3GTJ E;  2R92 E;  5M5X E;  5C4J F;  3GTP F;  1SMY E;  3S2D E;  3I4N F;  4MEY E;  4YFN E;  5FLM E;  3S1Q F;  1YNN K;  4OIP E;  3PO2 F;  4BY1 F;  1K83 E;  2E2I F;  2E2J E;  3S14 E;  1DZF A;  4Y52 E;  3FKI F;  4X6A F;  2A68 E;  1I50 E;  3GTM E;  5IP7 E;  4LJZ E;  2B63 F;  4BY7 E;  4QIW K;  4XSX E;  4G7O E;  2NVT F;  2VUM F;  2Y0S H;  3GTJ F;  5M5X F;  4YG2 E;  3RZO F;  4GZY E;  4LLG E;  4XLN E;  2BE5 E;  4C3J E;  3H0G E;  3EQL E;  4A3L F;  1I6H E;  3RZD F;  3S1R E;  3S15 E;  4G7Z E;  1I3Q E;  5C3E E;  4OIO E;  1QKL A;  5C44 E;  2A69 E;  5D4E E;  1SFO F;  1Y1V F;  2E2J F;  2JA6 E;  2JA7 E;  2E2H F;  2O5I E;  4Y7N E;  3HOY E;  5IPL E;  1Y1W E;  1I50 F;  2NVQ E;  3GTM F;  3GTG E;  5M5Y E;  1WCM F;  5IYD E;  2KRX A;  5D4C E;  4A3K E;  3HOU E;  1TWG E;  4A93 E;  5IYB F;  4XLP E;  3GTK E;  2NVX F;  3HOZ E;  3HOV F;  3I4M F;  3GTQ E;  1TWC E;  4OIQ E;  5M3M E;  3S16 F;  4BBR F;  4C3I F;  3S1R F;  3M3Y E;  3S1N F;  4A3G F;  1EIK A;  1I3Q F;  4LK1 E;  1TWF F;  2Y0S I;  5C3E F;  3HOW F;  3M4O F;  5IP9 F;  5M3F F;  2JA7 F;  4YFX E;  3S2H E;  4AYB K;  2NVQ F;  4KN7 E;  2JA5 E;  4A3C E;  3GTG F;  2PPB E;  2R93 E;  4Q5S E;  2R92 F;  4XSZ E;  4A3K F;  1R9T E;  4C3H E;  2R7Z E;  3HOU F;  3S2D F;  1TWG F;  4A93 F;  1ZYR E;  4BBS E;  4MQ9 E;  3GTK F;  3HOZ F;  3H3V F;  4A3F E;  5FLM F;  4BXX E;  3GTQ F;  3GTO E;  1TWA E;  4A3D E;  2YU9 E;  4A3J E;  1K83 F;  3S17 E;  5C4X E;  3S14 F;  4Y52 F;  2A6E E;  3S1M E;  3PO3 E;  5TMF E;  3CQZ E;  4AYB H;  5IP7 F;  4C2M E;  3S2H F;  4BY7 F;  4OIN E;  4KN4 E;  5BYH E;  2WB1 H;  2NVY E;  2R7Z F;  5IYC E;  5FJ8 E;  4BBS F;  4A3I E;  2WAQ K;  3K7A E;  4C3J F;  3H0G F;  3GTL E;  1I6H F;  4A3B E;  3S15 F;  5M5W E;  1TWA F;  5C4J E;  2JA6 F;  5C44 F;  2JA8 E;  3I4N E;  4Y7N F;  3HOY F;  3PO3 F;  1Y1W F;  3CQZ F;  1TWH E;  4C2M F;  4BY1 E;  3PO2 E;  5M5Y F;  5IYD F;  4Q4Z E;  2E2I E;  2O5J E;  4YFK E;  3WOD E;  2NVY F;  4X6A E;  2WAQ H;  4A3E E;  4A3M E;  1TWC F;  3GTL F;  5M3M F;  3DXJ E;  4KMU E;  2NVT E;  2VUM E;  3M3Y F;  2PMZ H;  2WB1 I;  1HQM E;  3RZO E;  2JA8 F;  1YNJ K;  4A3L E;  3RZD E;  1TWH F;  2JA5 F;  4A3C F;  5TMC E;  3M4O E;  2R93 F;  1SFO E;  1Y1V E;  5D4D E;  3HOX E;  1R9T F;  2E2H E;  4C3H F;  1I6V E;  4JK1 E;  4G7H E;  5E18 E;  4BXX F;  4A3F F;  3HKZ K;  4A3E F;  1WCM E;  4A3M F;  3GTO F;  4A3D F;  3GTP E;  2PMZ K;  2YU9 F;  4A3J F;  3S17 F;  5C4X F;  5IYB E;  3S1M F;  2NVX E;  3H3V G;  3HOV E;  3I4M E;  3S1Q E;  3S16 E;  4BBR E;  4C3I E;  4A3G E;  3S1N E;  3HOW E;  1IW7 E;  1TWF E;  4MEX E;  3FKI E;  5IP9 E;  5M3F E;  2A6H E;  3HOX F;  4OIR E;  5IYC F;  5FJ8 F;  5E17 E;  2B63 E;  4LK0 E;  4A3I F;  3K7A F;  3HKZ H;  2CW0 E;  4QIW H;  4A3B F;  4ZH4 E; 
#chains in the Genus database with same CATH homology
 5M5W F;  5C4J F;  3GTP F;  1SMY E;  3I4N F;  4MEY E;  4YFN E;  3S1Q F;  1YNN K;  4OIP E;  3PO2 F;  4BY1 F;  2E2I F;  3FKI F;  4X6A F;  2A68 E;  4LJZ E;  2B63 F;  4QIW K;  4XSX E;  4G7O E;  2NVT F;  2VUM F;  3GTJ F;  5M5X F;  4YG2 E;  3RZO F;  4GZY E;  4LLG E;  4XLN E;  2BE5 E;  3EQL E;  4A3L F;  3RZD F;  4G7Z E;  4OIO E;  1QKL A;  3M4O F;  2A69 E;  5D4E E;  1SFO F;  1Y1V F;  2E2J F;  2O5I E;  2O5J E;  2E2H F;  3GTM F;  1I50 F;  1WCM F;  2KRX A;  5D4C E;  5IYB F;  4XLP E;  2NVX F;  3HOV F;  3I4M F;  4OIQ E;  3S16 F;  4BBR F;  4C3I F;  3S1R F;  4A3G F;  3S1N F;  1I3Q F;  4LK1 E;  1TWF F;  2Y0S I;  5C3E F;  3HOW F;  5IP9 F;  5M3F F;  2JA7 F;  4YFX E;  4AYB K;  2NVQ F;  4KN7 E;  3GTG F;  2PPB E;  4Q5S E;  2R92 F;  4XSZ E;  4A3K F;  3S2D F;  5IPL E;  3HOU F;  1TWG F;  4A93 F;  1ZYR E;  4MQ9 E;  3GTK F;  3HOZ F;  5FLM F;  3GTQ F;  1K83 F;  3S14 F;  4Y52 F;  2A6E E;  5TMF E;  5IP7 F;  3S2H F;  4BY7 F;  4OIN E;  4KN4 E;  5BYH E;  2R7Z F;  4BBS F;  2WAQ K;  4C3J F;  3H0G F;  1I6H F;  3S15 F;  1TWA F;  2JA6 F;  5C44 F;  4Y7N F;  3HOY F;  3PO3 F;  1Y1W F;  3CQZ F;  4C2M F;  5M5Y F;  5IYD F;  4Q4Z E;  4YFK E;  3WOD E;  2NVY F;  1TWC F;  3GTL F;  5M3M F;  3DXJ E;  4KMU E;  3M3Y F;  2WB1 I;  1HQM E;  2JA8 F;  1YNJ K;  1TWH F;  2JA5 F;  4A3C F;  5TMC E;  2R93 F;  5D4D E;  1R9T F;  4C3H F;  1I6V E;  4JK1 E;  4G7H E;  5E18 E;  4BXX F;  4A3F F;  3HKZ K;  4A3E F;  4A3M F;  3GTO F;  4A3D F;  2PMZ K;  2YU9 F;  4A3J F;  3S17 F;  5C4X F;  3S1M F;  3H3V G;  1IW7 E;  4MEX E;  4OIR E;  5E17 E;  2A6H E;  3HOX F;  5IYC F;  5FJ8 F;  4LK0 E;  4A3I F;  3K7A F;  2CW0 E;  4A3B F;  4ZH4 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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