5JB6A

A simplified bpti variant containing 23 alanines out of 58 residues
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
58
structure length
58
Chain Sequence
RPAFCLEAPYAGPGAAAIIRYFYNAAAGAAQAFVYGGVAAKRNNFASAADALAACAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Pancreatic trypsin inhibitor
total genus 9
structure length 58
sequence length 58
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2016-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 5jb6A00
4ISOB 2FI5I 4U32X 1BPTA 2R9PE 3AUDA 5JB6A 3AUEA 8PTIA 1YLDB 1BZ5A 1BF0A 3M7QB 1T8MB 1B0CA 3BTFI 1YKTB 4ISNB 6PTIA 1IRHA 1ZR0B 2ODYE 3UOUB 1YLCB 1DTXA 1D0DB 3FP6I 1PITA 1ADZA 1G6XA 1T8OB 1BZXI 2UUXA 4TPII 3LDIA 1P2MB 3TGKI 2M99A 1Y62A 1LD6A 4PTIA 1AALA 2FTMB 4Y11I 2M01A 1T8LB 2ZJXA 4Y10I 3T62D 4NTWB 3P92E 1P2JI 4BNRI 2KNTA 1KTHA 1BTHP 1CBWD 3BTGI 1TAPA 1CA0D 5PTIA 1EJMB 2DDIA 3L3TE 2PTCI 3OTJI 5JB4A 2KCRA 2ZVXA 3WNYA 1F5RI 4NTXB 3FP8I 1P2QB 3U1JE 3BTHI 1DTKA 1JV9A 2TPII 1BRBI 3D65I 1ZJDB 2CA7A 1TAWB 7PTIA 5C67C 2W8XA 1FANA 3BTKI 4BD9B 1T7CB 3AUBA 1OA55 1UUAA 1EAWB 1T8NB 3AUIA 4DG4C 1P2NB 1CO7I 2LFLA 3BTDI 1TCPA 3CI7A 1JV8A 3BTTI 1BRCI 1P2KI 1MTND 1F7ZI 1FY8I 4Y0ZI 4NTYB 3AUGA 3BYBA 3TGJI 1KUNA 1DENA 3L33E 1P2OB 3OFWA 2DDJA 1FAKI 1BPIA 1BTIA 1P2II 3BTMI 2HEXA 1AAPA 2FI3I 1QLQA 3BTQI 4Y0YI 1KIGI 3LDJA 3AUCA 4WWYC 1TPAI 4U30W 1UUBA 4WXVC 1SHPA 9PTIA 2TGPI 2JOTA 2FI4I 1TFXC 3FP7J 1BHCA 1KNTA 1TOCR 2IJOI 1YC0I 4ISLB 1BUNB 2J6DA 2FTLI 2LFKA 1NAGA 1JC6A 3BTEI 5JB5A 1LD5A 3GYMI 3TGII 2KAII 3P95E 3LDMA 4BQDA 2UUYB 1BIKA 3TPII 1DEMA 1K6UA 2RA3C 3BTWI 4DTGK 5JB7A 3AUHA 1OA65 3UIRC 1D0DA
chains in the Genus database with same CATH superfamily
4ISOB 2FI5I 4U32X 1BPTA 2R9PE 3AUDA 5JB6A 3AUEA 8PTIA 1YLDB 1BZ5A 1BF0A 3M7QB 1T8MB 1B0CA 3BTFI 1YKTB 4ISNB 6PTIA 1IRHA 1ZR0B 2ODYE 3UOUB 1YLCB 1DTXA 1D0DB 3FP6I 1PITA 1ADZA 1G6XA 1T8OB 1BZXI 2UUXA 4TPII 3LDIA 1P2MB 3TGKI 2M99A 1Y62A 1LD6A 4PTIA 1AALA 2FTMB 4Y11I 2M01A 1T8LB 2ZJXA 4Y10I 3T62D 4NTWB 3P92E 1P2JI 4BNRI 2KNTA 1KTHA 1BTHP 1CBWD 3BTGI 1TAPA 1CA0D 5PTIA 1EJMB 2DDIA 3L3TE 2PTCI 3OTJI 5JB4A 2KCRA 2ZVXA 3WNYA 1F5RI 4NTXB 3FP8I 1P2QB 3U1JE 3BTHI 1DTKA 1JV9A 2TPII 1BRBI 3D65I 1ZJDB 2CA7A 1TAWB 7PTIA 5C67C 2W8XA 1FANA 3BTKI 4BD9B 1T7CB 3AUBA 1OA55 1UUAA 1EAWB 1T8NB 3AUIA 4DG4C 1P2NB 1CO7I 2LFLA 3BTDI 1TCPA 3CI7A 1JV8A 3BTTI 1BRCI 1P2KI 1MTND 1F7ZI 1FY8I 4Y0ZI 4NTYB 3AUGA 3BYBA 3TGJI 1KUNA 1DENA 3L33E 1P2OB 3OFWA 2DDJA 1FAKI 1BPIA 1BTIA 1P2II 3BTMI 2HEXA 1AAPA 2FI3I 1QLQA 3BTQI 4Y0YI 1KIGI 3LDJA 3AUCA 4WWYC 1TPAI 4U30W 1UUBA 4WXVC 1SHPA 9PTIA 2TGPI 2JOTA 2FI4I 1TFXC 3FP7J 1BHCA 1KNTA 1TOCR 2IJOI 1YC0I 4ISLB 1BUNB 2J6DA 2FTLI 2LFKA 1NAGA 1JC6A 3BTEI 5JB5A 1LD5A 3GYMI 3TGII 2KAII 3P95E 3LDMA 4BQDA 2UUYB 1BIKA 3TPII 1DEMA 1K6UA 2RA3C 3BTWI 4DTGK 5JB7A 3AUHA 1OA65 3UIRC 1D0DA
chains in the Genus database with same CATH topology
4ISOB 2FI5I 4U32X 1BPTA 2R9PE 3AUDA 5JB6A 3AUEA 8PTIA 1YLDB 1BZ5A 1BF0A 3M7QB 1T8MB 1B0CA 3BTFI 1YKTB 4ISNB 6PTIA 1IRHA 1ZR0B 2ODYE 3UOUB 1YLCB 1DTXA 1D0DB 3FP6I 1PITA 1ADZA 1G6XA 1T8OB 1BZXI 2UUXA 4TPII 3LDIA 1P2MB 3TGKI 2M99A 1Y62A 1LD6A 4PTIA 1AALA 2FTMB 4Y11I 2M01A 1T8LB 2ZJXA 4Y10I 3T62D 4NTWB 3P92E 1P2JI 4BNRI 2KNTA 1KTHA 1BTHP 1CBWD 3BTGI 1TAPA 1CA0D 5PTIA 1EJMB 2DDIA 3L3TE 2PTCI 3OTJI 5JB4A 2KCRA 2ZVXA 3WNYA 1F5RI 4NTXB 3FP8I 1P2QB 3U1JE 3BTHI 1DTKA 1JV9A 2TPII 1BRBI 3D65I 1ZJDB 2CA7A 1TAWB 7PTIA 5C67C 2W8XA 1FANA 3BTKI 4BD9B 1T7CB 3AUBA 1OA55 1UUAA 1EAWB 1T8NB 3AUIA 4DG4C 1P2NB 1CO7I 2LFLA 3BTDI 1TCPA 3CI7A 1JV8A 3BTTI 1BRCI 1P2KI 1MTND 1F7ZI 1FY8I 4Y0ZI 4NTYB 3AUGA 3BYBA 3TGJI 1KUNA 1DENA 3L33E 1P2OB 3OFWA 2DDJA 1FAKI 1BPIA 1BTIA 1P2II 3BTMI 2HEXA 1AAPA 2FI3I 1QLQA 3BTQI 4Y0YI 1KIGI 3LDJA 3AUCA 4WWYC 1TPAI 4U30W 1UUBA 4WXVC 1SHPA 9PTIA 2TGPI 2JOTA 2FI4I 1TFXC 3FP7J 1BHCA 1KNTA 1TOCR 2IJOI 1YC0I 4ISLB 1BUNB 2J6DA 2FTLI 2LFKA 1NAGA 1JC6A 3BTEI 5JB5A 1LD5A 3GYMI 3TGII 2KAII 3P95E 3LDMA 4BQDA 2UUYB 1BIKA 3TPII 1DEMA 1K6UA 2RA3C 3BTWI 4DTGK 5JB7A 3AUHA 1OA65 3UIRC 1D0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ISO B;  2FI5 I;  4U32 X;  1BPT A;  2R9P E;  3AUD A;  5JB6 A;  3AUE A;  8PTI A;  1YLD B;  1BZ5 A;  1BF0 A;  3M7Q B;  1T8M B;  1B0C A;  3BTF I;  1YKT B;  4ISN B;  6PTI A;  1IRH A;  1ZR0 B;  2ODY E;  3UOU B;  1YLC B;  1DTX A;  1D0D B;  3FP6 I;  1PIT A;  1ADZ A;  1G6X A;  1T8O B;  1BZX I;  2UUX A;  4TPI I;  3LDI A;  1P2M B;  3TGK I;  2M99 A;  1Y62 A;  1LD6 A;  4PTI A;  1AAL A;  2FTM B;  4Y11 I;  2M01 A;  1T8L B;  2ZJX A;  4Y10 I;  3T62 D;  4NTW B;  3P92 E;  1P2J I;  4BNR I;  2KNT A;  1KTH A;  1BTH P;  1CBW D;  3BTG I;  1TAP A;  1CA0 D;  5PTI A;  1EJM B;  2DDI A;  3L3T E;  2PTC I;  3OTJ I;  5JB4 A;  2KCR A;  2ZVX A;  3WNY A;  1F5R I;  4NTX B;  3FP8 I;  1P2Q B;  3U1J E;  3BTH I;  1DTK A;  1JV9 A;  2TPI I;  1BRB I;  3D65 I;  1ZJD B;  2CA7 A;  1TAW B;  7PTI A;  5C67 C;  2W8X A;  1FAN A;  3BTK I;  4BD9 B;  1T7C B;  3AUB A;  1OA5 5;  1UUA A;  1EAW B;  1T8N B;  3AUI A;  4DG4 C;  1P2N B;  1CO7 I;  2LFL A;  3BTD I;  1TCP A;  3CI7 A;  1JV8 A;  3BTT I;  1BRC I;  1P2K I;  1MTN D;  1F7Z I;  1FY8 I;  4Y0Z I;  4NTY B;  3AUG A;  3BYB A;  3TGJ I;  1KUN A;  1DEN A;  3L33 E;  1P2O B;  3OFW A;  2DDJ A;  1FAK I;  1BPI A;  1BTI A;  1P2I I;  3BTM I;  2HEX A;  1AAP A;  2FI3 I;  1QLQ A;  3BTQ I;  4Y0Y I;  1KIG I;  3LDJ A;  3AUC A;  4WWY C;  1TPA I;  4U30 W;  1UUB A;  4WXV C;  1SHP A;  9PTI A;  2TGP I;  2JOT A;  2FI4 I;  1TFX C;  3FP7 J;  1BHC A;  1KNT A;  1TOC R;  2IJO I;  1YC0 I;  4ISL B;  1BUN B;  2J6D A;  2FTL I;  2LFK A;  1NAG A;  1JC6 A;  3BTE I;  5JB5 A;  1LD5 A;  3GYM I;  3TGI I;  2KAI I;  3P95 E;  3LDM A;  4BQD A;  2UUY B;  1BIK A;  3TPI I;  1DEM A;  1K6U A;  2RA3 C;  3BTW I;  4DTG K;  5JB7 A;  3AUH A;  1OA6 5;  3UIR C;  1D0D A; 
#chains in the Genus database with same CATH topology
 4ISO B;  2FI5 I;  4U32 X;  1BPT A;  2R9P E;  3AUD A;  5JB6 A;  3AUE A;  8PTI A;  1YLD B;  1BZ5 A;  1BF0 A;  3M7Q B;  1T8M B;  1B0C A;  3BTF I;  1YKT B;  4ISN B;  6PTI A;  1IRH A;  1ZR0 B;  2ODY E;  3UOU B;  1YLC B;  1DTX A;  1D0D B;  3FP6 I;  1PIT A;  1ADZ A;  1G6X A;  1T8O B;  1BZX I;  2UUX A;  4TPI I;  3LDI A;  1P2M B;  3TGK I;  2M99 A;  1Y62 A;  1LD6 A;  4PTI A;  1AAL A;  2FTM B;  4Y11 I;  2M01 A;  1T8L B;  2ZJX A;  4Y10 I;  3T62 D;  4NTW B;  3P92 E;  1P2J I;  4BNR I;  2KNT A;  1KTH A;  1BTH P;  1CBW D;  3BTG I;  1TAP A;  1CA0 D;  5PTI A;  1EJM B;  2DDI A;  3L3T E;  2PTC I;  3OTJ I;  5JB4 A;  2KCR A;  2ZVX A;  3WNY A;  1F5R I;  4NTX B;  3FP8 I;  1P2Q B;  3U1J E;  3BTH I;  1DTK A;  1JV9 A;  2TPI I;  1BRB I;  3D65 I;  1ZJD B;  2CA7 A;  1TAW B;  7PTI A;  5C67 C;  2W8X A;  1FAN A;  3BTK I;  4BD9 B;  1T7C B;  3AUB A;  1OA5 5;  1UUA A;  1EAW B;  1T8N B;  3AUI A;  4DG4 C;  1P2N B;  1CO7 I;  2LFL A;  3BTD I;  1TCP A;  3CI7 A;  1JV8 A;  3BTT I;  1BRC I;  1P2K I;  1MTN D;  1F7Z I;  1FY8 I;  4Y0Z I;  4NTY B;  3AUG A;  3BYB A;  3TGJ I;  1KUN A;  1DEN A;  3L33 E;  1P2O B;  3OFW A;  2DDJ A;  1FAK I;  1BPI A;  1BTI A;  1P2I I;  3BTM I;  2HEX A;  1AAP A;  2FI3 I;  1QLQ A;  3BTQ I;  4Y0Y I;  1KIG I;  3LDJ A;  3AUC A;  4WWY C;  1TPA I;  4U30 W;  1UUB A;  4WXV C;  1SHP A;  9PTI A;  2TGP I;  2JOT A;  2FI4 I;  1TFX C;  3FP7 J;  1BHC A;  1KNT A;  1TOC R;  2IJO I;  1YC0 I;  4ISL B;  1BUN B;  2J6D A;  2FTL I;  2LFK A;  1NAG A;  1JC6 A;  3BTE I;  5JB5 A;  1LD5 A;  3GYM I;  3TGI I;  2KAI I;  3P95 E;  3LDM A;  4BQD A;  2UUY B;  1BIK A;  3TPI I;  1DEM A;  1K6U A;  2RA3 C;  3BTW I;  4DTG K;  5JB7 A;  3AUH A;  1OA6 5;  3UIR C;  1D0D A; 
#chains in the Genus database with same CATH homology
 4ISO B;  2FI5 I;  4U32 X;  1BPT A;  2R9P E;  3AUD A;  5JB6 A;  3AUE A;  8PTI A;  1YLD B;  1BZ5 A;  1BF0 A;  3M7Q B;  1T8M B;  1B0C A;  3BTF I;  1YKT B;  4ISN B;  6PTI A;  1IRH A;  1ZR0 B;  2ODY E;  3UOU B;  1YLC B;  1DTX A;  1D0D B;  3FP6 I;  1PIT A;  1ADZ A;  1G6X A;  1T8O B;  1BZX I;  2UUX A;  4TPI I;  3LDI A;  1P2M B;  3TGK I;  2M99 A;  1Y62 A;  1LD6 A;  4PTI A;  1AAL A;  2FTM B;  4Y11 I;  2M01 A;  1T8L B;  2ZJX A;  4Y10 I;  3T62 D;  4NTW B;  3P92 E;  1P2J I;  4BNR I;  2KNT A;  1KTH A;  1BTH P;  1CBW D;  3BTG I;  1TAP A;  1CA0 D;  5PTI A;  1EJM B;  2DDI A;  3L3T E;  2PTC I;  3OTJ I;  5JB4 A;  2KCR A;  2ZVX A;  3WNY A;  1F5R I;  4NTX B;  3FP8 I;  1P2Q B;  3U1J E;  3BTH I;  1DTK A;  1JV9 A;  2TPI I;  1BRB I;  3D65 I;  1ZJD B;  2CA7 A;  1TAW B;  7PTI A;  5C67 C;  2W8X A;  1FAN A;  3BTK I;  4BD9 B;  1T7C B;  3AUB A;  1OA5 5;  1UUA A;  1EAW B;  1T8N B;  3AUI A;  4DG4 C;  1P2N B;  1CO7 I;  2LFL A;  3BTD I;  1TCP A;  3CI7 A;  1JV8 A;  3BTT I;  1BRC I;  1P2K I;  1MTN D;  1F7Z I;  1FY8 I;  4Y0Z I;  4NTY B;  3AUG A;  3BYB A;  3TGJ I;  1KUN A;  1DEN A;  3L33 E;  1P2O B;  3OFW A;  2DDJ A;  1FAK I;  1BPI A;  1BTI A;  1P2I I;  3BTM I;  2HEX A;  1AAP A;  2FI3 I;  1QLQ A;  3BTQ I;  4Y0Y I;  1KIG I;  3LDJ A;  3AUC A;  4WWY C;  1TPA I;  4U30 W;  1UUB A;  4WXV C;  1SHP A;  9PTI A;  2TGP I;  2JOT A;  2FI4 I;  1TFX C;  3FP7 J;  1BHC A;  1KNT A;  1TOC R;  2IJO I;  1YC0 I;  4ISL B;  1BUN B;  2J6D A;  2FTL I;  2LFK A;  1NAG A;  1JC6 A;  3BTE I;  5JB5 A;  1LD5 A;  3GYM I;  3TGI I;  2KAI I;  3P95 E;  3LDM A;  4BQD A;  2UUY B;  1BIK A;  3TPI I;  1DEM A;  1K6U A;  2RA3 C;  3BTW I;  4DTG K;  5JB7 A;  3AUH A;  1OA6 5;  3UIR C;  1D0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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