5M3FE

Yeast rna polymerase i elongation complex at 3.8a
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
212
structure length
212
Chain Sequence
ENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of RNA polymerase I transcribing ribosomal DNA genes.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 43
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2016-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5m3fE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5m3fE02
2R93E 3I4ME 4C3IE 2B63E 3HOUE 2WAQH 3FKIE 1TWAE 5IYCE 5IP9E 4C3HE 5M5WE 3GTJE 4AYBH 4A3DE 3PO2E 3HOYE 3S17E 2YU9E 4C2ME 4A3KE 1SFOE 3GTGE 5M3ME 3HOVE 3HOWE 2NVYE 1K83E 3S1RE 3S15E 3RZOE 5M5XE 3S1ME 3S2HE 5IP7E 4BBRE 4A3ME 5C4JE 4BBSE 1WCME 2NVXE 1I3QE 3HKZH 4X6AE 4QIWH 3S14E 3GTME 4C3JE 3HOZE 4A93E 4BXXE 5C3EE 3GTKE 4Y7NE 1DZFA 3H0GE 4A3EE 1TWFE 3HOXE 5M5YE 2E2IE 4BY1E 5M3FE 3RZDE 2E2HE 3M3YE 2JA5E 3GTQE 4A3BE 4A3LE 2R92E 1TWGE 5FLME 2WB1H 3S16E 1EIKA 2JA6E 1TWCE 4A3FE 4BY7E 3I4NE 2JA7E 2JA8E 3GTPE 3PO3E 4Y52E 3H3VF 1TWHE 3S1QE 2NVQE 3S1NE 5C44E 1R9TE 4A3JE 4A3CE 2VUME 3S2DE 4A3IE 2PMZH 3GTLE 1Y1VE 3GTOE 2E2JE 3M4OE 2Y0SH 1Y1WE 2NVTE 4A3GE 5IYDE 3CQZE 1I50E 2R7ZE 1I6HE 5IYBE 5C4XE 5FJ8E 3K7AE
chains in the Genus database with same CATH superfamily
4A3DF 2R93E 3HOYF 2WB1I 3EQLE 4OIOE 3HKZK 3I4ME 4KN4E 4C3IE 2B63E 3HOUE 1YNNK 2WAQH 3H0GF 4QIWK 3FKIE 4XLNE 1TWAE 4A3KF 3GTGF 3HOVF 5IYCE 3HOWF 2NVYF 4G7OE 5IP9E 3S1RF 3S15F 4OIQE 4C3HE 5M5WE 1HQME 5M5XF 3GTJE 4AYBH 4MEXE 5IP7F 2E2HF 2A68E 4MEYE 4AYBK 5BYHE 4A3DE 3PO2E 3HOYE 3DXJE 1WCMF 4G7ZE 1TWGF 3S17E 5D4CE 3GTQF 4BBSF 2YU9E 4C2ME 5FLMF 1I3QF 4A3KE 1SFOE 3GTGE 2JA6F 5M3ME 3HOVE 4X6AF 3HOWE 2NVYE 1K83E 4A3FF 2JA7F 3S1RE 3S15E 4YG2E 4C3JF 2O5IE 3GTMF 4XSXE 3RZOE 2JA8F 3GTPF 5M5XE 3S1ME 3PO3F 3S2HE 5IP7E 5E18E 5D4DE 4BBRE 4A3ME 5C4JE 4XSZE 4BBSE 1WCME 2NVQF 2NVXE 5C3EF 4GZYE 1I3QE 3HKZH 4X6AE 4QIWH 4Y7NF 3GTKF 3S14E 1R9TF 4A3EF 3GTME 4C3JE 3HOZE 4A93E 4A3JF 1TWFF 3HOXF 4KMUE 4BY1F 5M5YF 2E2IF 2CW0E 4BXXE 4C2MF 5M3FF 4OIRE 3S2DF 3RZDF 5C3EE 4KN7E 3M3YF 2JA5F 2R92F 4Q4ZE 4A3BF 4A3LF 4YFXE 3GTKE 4Y7NE 2A6EE 1DZFA 3H0GE 4LK0E 4A3EE 1Y1VF 3GTLF 4Q5SE 3S16F 1TWFE 1TWCF 3HOXE 1QKLA 5M5YE 2E2IE 4BY1E 4LJZE 4BY7F 2E2JF 5M3FE 3I4NF 4G7HE 4Y52F 3RZDE 2E2HE 4JK1E 1TWHF 3S1QF 3M3YE 2JA5E 3GTQE 4A3BE 4A3LE 2R92E 5E17E 1TWGE 5TMFE 1Y1WF 5FLME 1YNJK 2WB1H 3S16E 2PMZK 3S1NF 1EIKA 5IPLE 2JA6E 5C44F 1TWCE 2O5JE 4A3FE 4BY7E 3I4NE 4YFNE 2JA7E 2JA8E 2Y0SI 3GTPE 3PO3E 4Y52E 3CQZF 1I6HF 2VUMF 2R7ZF 4A3CF 3H3VF 1TWHE 4LK1E 3S1QE 4A3IF 5FJ8F 2R93F 2NVQE 3I4MF 4C3IF 2B63F 3S1NE 5C44E 1TWAF 2A6HE 1IW7E 1R9TE 5IYCF 3GTOF 5IP9F 4A3JE 4A3CE 2KRXA 2VUME 3WODE 3M4OF 3S2DE 2A69E 1SMYE 4A3IE 3PO2F 5D4EE 3S17F 1ZYRE 2YU9F 4MQ9E 3S14F 1SFOF 2PMZH 2WAQK 5M3MF 2PPBE 3GTLE 1Y1VE 3GTOE 1K83F 4ZH4E 3H3VG 1I6VE 2NVTF 3RZOF 2E2JE 3S1MF 4A3GF 3M4OE 3S2HF 2Y0SH 5IYDF 4BBRF 1I50F 5C4JF 4OINE 2NVXF 5IYBF 5C4XF 3K7AF 1Y1WE 4XLPE 3HOUF 4OIPE 3FKIF 4A93F 2NVTE 4LLGE 4A3GE 4BXXF 5IYDE 4A3MF 3CQZE 1I50E 2R7ZE 5TMCE 4C3HF 1I6HE 5M5WF 3GTJF 4YFKE 3HOZF 2BE5E 5IYBE 5C4XE 5FJ8E 3K7AE
chains in the Genus database with same CATH topology
2R93E 3I4ME 4C3IE 2B63E 3HOUE 2WAQH 3FKIE 1TWAE 5IYCE 5IP9E 4C3HE 5M5WE 3GTJE 4AYBH 4A3DE 3PO2E 3HOYE 3S17E 2YU9E 4C2ME 4A3KE 1SFOE 3GTGE 5M3ME 3HOVE 3HOWE 2NVYE 1K83E 3S1RE 3S15E 3RZOE 5M5XE 3S1ME 3S2HE 5IP7E 4BBRE 4A3ME 5C4JE 4BBSE 1WCME 2NVXE 1I3QE 3HKZH 4X6AE 4QIWH 3S14E 3GTME 4C3JE 3HOZE 4A93E 4BXXE 5C3EE 3GTKE 4Y7NE 1DZFA 3H0GE 4A3EE 1TWFE 3HOXE 5M5YE 2E2IE 4BY1E 5M3FE 3RZDE 2E2HE 3M3YE 2JA5E 3GTQE 4A3BE 4A3LE 2R92E 1TWGE 5FLME 2WB1H 3S16E 1EIKA 2JA6E 1TWCE 4A3FE 4BY7E 3I4NE 2JA7E 2JA8E 3GTPE 3PO3E 4Y52E 3H3VF 1TWHE 3S1QE 2NVQE 3S1NE 5C44E 1R9TE 4A3JE 4A3CE 2VUME 3S2DE 4A3IE 2PMZH 3GTLE 1Y1VE 3GTOE 2E2JE 3M4OE 2Y0SH 1Y1WE 2NVTE 4A3GE 5IYDE 3CQZE 1I50E 2R7ZE 1I6HE 5IYBE 5C4XE 5FJ8E 3K7AE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R93 E;  3I4M E;  4C3I E;  2B63 E;  3HOU E;  2WAQ H;  3FKI E;  1TWA E;  5IYC E;  5IP9 E;  4C3H E;  5M5W E;  3GTJ E;  4AYB H;  4A3D E;  3PO2 E;  3HOY E;  3S17 E;  2YU9 E;  4C2M E;  4A3K E;  1SFO E;  3GTG E;  5M3M E;  3HOV E;  3HOW E;  2NVY E;  1K83 E;  3S1R E;  3S15 E;  3RZO E;  5M5X E;  3S1M E;  3S2H E;  5IP7 E;  4BBR E;  4A3M E;  5C4J E;  4BBS E;  1WCM E;  2NVX E;  1I3Q E;  3HKZ H;  4X6A E;  4QIW H;  3S14 E;  3GTM E;  4C3J E;  3HOZ E;  4A93 E;  4BXX E;  5C3E E;  3GTK E;  4Y7N E;  1DZF A;  3H0G E;  4A3E E;  1TWF E;  3HOX E;  5M5Y E;  2E2I E;  4BY1 E;  5M3F E;  3RZD E;  2E2H E;  3M3Y E;  2JA5 E;  3GTQ E;  4A3B E;  4A3L E;  2R92 E;  1TWG E;  5FLM E;  2WB1 H;  3S16 E;  1EIK A;  2JA6 E;  1TWC E;  4A3F E;  4BY7 E;  3I4N E;  2JA7 E;  2JA8 E;  3GTP E;  3PO3 E;  4Y52 E;  3H3V F;  1TWH E;  3S1Q E;  2NVQ E;  3S1N E;  5C44 E;  1R9T E;  4A3J E;  4A3C E;  2VUM E;  3S2D E;  4A3I E;  2PMZ H;  3GTL E;  1Y1V E;  3GTO E;  2E2J E;  3M4O E;  2Y0S H;  1Y1W E;  2NVT E;  4A3G E;  5IYD E;  3CQZ E;  1I50 E;  2R7Z E;  1I6H E;  5IYB E;  5C4X E;  5FJ8 E;  3K7A E; 
#chains in the Genus database with same CATH topology
 4A3D F;  2R93 E;  3HOY F;  2WB1 I;  3EQL E;  4OIO E;  3HKZ K;  3I4M E;  4KN4 E;  4C3I E;  2B63 E;  3HOU E;  1YNN K;  2WAQ H;  3H0G F;  4QIW K;  3FKI E;  4XLN E;  1TWA E;  4A3K F;  3GTG F;  3HOV F;  5IYC E;  3HOW F;  2NVY F;  4G7O E;  5IP9 E;  3S1R F;  3S15 F;  4OIQ E;  4C3H E;  5M5W E;  1HQM E;  5M5X F;  3GTJ E;  4AYB H;  4MEX E;  5IP7 F;  2E2H F;  2A68 E;  4MEY E;  4AYB K;  5BYH E;  4A3D E;  3PO2 E;  3HOY E;  3DXJ E;  1WCM F;  4G7Z E;  1TWG F;  3S17 E;  5D4C E;  3GTQ F;  4BBS F;  2YU9 E;  4C2M E;  5FLM F;  1I3Q F;  4A3K E;  1SFO E;  3GTG E;  2JA6 F;  5M3M E;  3HOV E;  4X6A F;  3HOW E;  2NVY E;  1K83 E;  4A3F F;  2JA7 F;  3S1R E;  3S15 E;  4YG2 E;  4C3J F;  2O5I E;  3GTM F;  4XSX E;  3RZO E;  2JA8 F;  3GTP F;  5M5X E;  3S1M E;  3PO3 F;  3S2H E;  5IP7 E;  5E18 E;  5D4D E;  4BBR E;  4A3M E;  5C4J E;  4XSZ E;  4BBS E;  1WCM E;  2NVQ F;  2NVX E;  5C3E F;  4GZY E;  1I3Q E;  3HKZ H;  4X6A E;  4QIW H;  4Y7N F;  3GTK F;  3S14 E;  1R9T F;  4A3E F;  3GTM E;  4C3J E;  3HOZ E;  4A93 E;  4A3J F;  1TWF F;  3HOX F;  4KMU E;  4BY1 F;  5M5Y F;  2E2I F;  2CW0 E;  4BXX E;  4C2M F;  5M3F F;  4OIR E;  3S2D F;  3RZD F;  5C3E E;  4KN7 E;  3M3Y F;  2JA5 F;  2R92 F;  4Q4Z E;  4A3B F;  4A3L F;  4YFX E;  3GTK E;  4Y7N E;  2A6E E;  1DZF A;  3H0G E;  4LK0 E;  4A3E E;  1Y1V F;  3GTL F;  4Q5S E;  3S16 F;  1TWF E;  1TWC F;  3HOX E;  1QKL A;  5M5Y E;  2E2I E;  4BY1 E;  4LJZ E;  4BY7 F;  2E2J F;  5M3F E;  3I4N F;  4G7H E;  4Y52 F;  3RZD E;  2E2H E;  4JK1 E;  1TWH F;  3S1Q F;  3M3Y E;  2JA5 E;  3GTQ E;  4A3B E;  4A3L E;  2R92 E;  5E17 E;  1TWG E;  5TMF E;  1Y1W F;  5FLM E;  1YNJ K;  2WB1 H;  3S16 E;  2PMZ K;  3S1N F;  1EIK A;  5IPL E;  2JA6 E;  5C44 F;  1TWC E;  2O5J E;  4A3F E;  4BY7 E;  3I4N E;  4YFN E;  2JA7 E;  2JA8 E;  2Y0S I;  3GTP E;  3PO3 E;  4Y52 E;  3CQZ F;  1I6H F;  2VUM F;  2R7Z F;  4A3C F;  3H3V F;  1TWH E;  4LK1 E;  3S1Q E;  4A3I F;  5FJ8 F;  2R93 F;  2NVQ E;  3I4M F;  4C3I F;  2B63 F;  3S1N E;  5C44 E;  1TWA F;  2A6H E;  1IW7 E;  1R9T E;  5IYC F;  3GTO F;  5IP9 F;  4A3J E;  4A3C E;  2KRX A;  2VUM E;  3WOD E;  3M4O F;  3S2D E;  2A69 E;  1SMY E;  4A3I E;  3PO2 F;  5D4E E;  3S17 F;  1ZYR E;  2YU9 F;  4MQ9 E;  3S14 F;  1SFO F;  2PMZ H;  2WAQ K;  5M3M F;  2PPB E;  3GTL E;  1Y1V E;  3GTO E;  1K83 F;  4ZH4 E;  3H3V G;  1I6V E;  2NVT F;  3RZO F;  2E2J E;  3S1M F;  4A3G F;  3M4O E;  3S2H F;  2Y0S H;  5IYD F;  4BBR F;  1I50 F;  5C4J F;  4OIN E;  2NVX F;  5IYB F;  5C4X F;  3K7A F;  1Y1W E;  4XLP E;  3HOU F;  4OIP E;  3FKI F;  4A93 F;  2NVT E;  4LLG E;  4A3G E;  4BXX F;  5IYD E;  4A3M F;  3CQZ E;  1I50 E;  2R7Z E;  5TMC E;  4C3H F;  1I6H E;  5M5W F;  3GTJ F;  4YFK E;  3HOZ F;  2BE5 E;  5IYB E;  5C4X E;  5FJ8 E;  3K7A E; 
#chains in the Genus database with same CATH homology
 2R93 E;  3I4M E;  4C3I E;  2B63 E;  3HOU E;  2WAQ H;  3FKI E;  1TWA E;  5IYC E;  5IP9 E;  4C3H E;  5M5W E;  3GTJ E;  4AYB H;  4A3D E;  3PO2 E;  3HOY E;  3S17 E;  2YU9 E;  4C2M E;  4A3K E;  1SFO E;  3GTG E;  5M3M E;  3HOV E;  3HOW E;  2NVY E;  1K83 E;  3S1R E;  3S15 E;  3RZO E;  5M5X E;  3S1M E;  3S2H E;  5IP7 E;  4BBR E;  4A3M E;  5C4J E;  4BBS E;  1WCM E;  2NVX E;  1I3Q E;  3HKZ H;  4X6A E;  4QIW H;  3S14 E;  3GTM E;  4C3J E;  3HOZ E;  4A93 E;  4BXX E;  5C3E E;  3GTK E;  4Y7N E;  1DZF A;  3H0G E;  4A3E E;  1TWF E;  3HOX E;  5M5Y E;  2E2I E;  4BY1 E;  5M3F E;  3RZD E;  2E2H E;  3M3Y E;  2JA5 E;  3GTQ E;  4A3B E;  4A3L E;  2R92 E;  1TWG E;  5FLM E;  2WB1 H;  3S16 E;  1EIK A;  2JA6 E;  1TWC E;  4A3F E;  4BY7 E;  3I4N E;  2JA7 E;  2JA8 E;  3GTP E;  3PO3 E;  4Y52 E;  3H3V F;  1TWH E;  3S1Q E;  2NVQ E;  3S1N E;  5C44 E;  1R9T E;  4A3J E;  4A3C E;  2VUM E;  3S2D E;  4A3I E;  2PMZ H;  3GTL E;  1Y1V E;  3GTO E;  2E2J E;  3M4O E;  2Y0S H;  1Y1W E;  2NVT E;  4A3G E;  5IYD E;  3CQZ E;  1I50 E;  2R7Z E;  1I6H E;  5IYB E;  5C4X E;  5FJ8 E;  3K7A E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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