5M3ME

Free monomeric rna polymerase i at 4.0a resolution
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
212
structure length
212
Chain Sequence
ENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of RNA polymerase I transcribing ribosomal DNA genes.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 48
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2016-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5m3mE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5m3mE02
3GTOE 2R92E 1Y1WE 2NVTE 1WCME 4A3EE 4BY1E 2E2IE 1EIKA 1Y1VE 3HOZE 3HOXE 3S1QE 2YU9E 1SFOE 3M4OE 2JA7E 4A3KE 3GTJE 3S14E 4C3HE 1TWGE 5M5XE 4Y52E 3GTQE 4C3IE 5C4JE 2NVXE 3K7AE 2WAQH 3M3YE 1TWAE 4A3BE 4QIWH 3S1RE 3HOWE 4BXXE 4BBSE 3GTME 3GTKE 2JA5E 4C2ME 1I50E 4A3ME 4A3LE 5M3FE 5IYDE 2VUME 3S2DE 5IP9E 5IP7E 3GTPE 1DZFA 1K83E 3HOUE 3CQZE 2NVQE 1TWHE 2PMZH 2E2HE 4X6AE 3RZOE 2NVYE 2R7ZE 3FKIE 5FJ8E 3HOVE 4BBRE 4A3FE 2JA8E 3S16E 1TWCE 3GTGE 5IYBE 3S15E 4A3CE 3PO2E 2Y0SH 2B63E 3S1NE 3H0GE 4Y7NE 3GTLE 5M5WE 3S2HE 4A3DE 4C3JE 4A3GE 5IYCE 2WB1H 1I6HE 4A93E 3I4ME 4BY7E 5C44E 3I4NE 5M3ME 3S17E 3S1ME 3HKZH 1TWFE 4A3JE 3RZDE 5FLME 2R93E 5M5YE 4AYBH 3PO3E 4A3IE 5C3EE 3H3VF 5C4XE 2E2JE 2JA6E 3HOYE 1I3QE 1R9TE
chains in the Genus database with same CATH superfamily
2NVXF 2CW0E 3GTOE 2R92E 1Y1WE 2NVTE 1WCME 4A3EE 4BY1E 3K7AF 2E2IE 4Q4ZE 1EIKA 1Y1VE 3HOZE 3HOXE 3M3YF 2O5JE 3HKZK 4A3BF 3S1QE 2YU9E 1SFOE 3M4OE 3S1RF 4YFXE 2E2HF 3HOWF 4BXXF 2JA7E 4OIOE 4AYBK 4A3KE 3GTJE 3S14E 4C3HE 1TWGE 5M5XE 2A68E 4Y52E 4LK1E 2O5IE 3GTMF 3GTQE 2JA5F 4C2MF 4C3IE 5C4JE 4YG2E 4ZH4E 2PPBE 2NVXE 3S16F 2BE5E 4MQ9E 4A3MF 3K7AE 4A3LF 2WAQH 5IYDF 2VUMF 3M3YE 5IP9F 1TWAE 4JK1E 3S2DF 4A3BE 4QIWH 4XLPE 3H3VG 5TMCE 3S1RE 3HOWE 3HOVF 4BXXE 5IP7F 4A3GF 2KRXA 3GTPF 1I6HF 1K83F 3HOUF 5C4JF 4KMUE 3CQZF 2NVQF 1TWHF 4BBSE 4X6AF 3GTME 3GTKE 2JA5E 4C2ME 1I50E 5M3MF 1SMYE 2NVYF 2R7ZF 3RZOF 5D4CE 4A3ME 5BYHE 3FKIF 4A3LE 5M3FE 1YNNK 5IYDE 2WAQK 2VUME 3S2DE 5IP9E 4BBRF 5FJ8F 4A3FF 1TWCF 5D4EE 5M5YF 3RZDF 2JA8F 4QIWK 3GTGF 2A69E 5IYBF 1HQME 3S15F 4A3CF 3PO2F 5IP7E 2B63F 4OIRE 3S1NF 3GTPE 3H0GF 1DZFA 1K83E 3HOUE 4Y7NF 4OINE 2JA6F 3GTLF 3CQZE 5M5WF 2NVQE 1TWHE 3S2HF 4A3DF 2PMZH 4C3JF 2E2HE 4X6AE 1YNJK 3GTOF 3RZOE 2NVYE 2R7ZE 4KN7E 5IYCF 5E18E 4GZYE 4LLGE 4A93F 4BY7F 3I4MF 3FKIE 1Y1VF 5C44F 3I4NF 1I6VE 5FJ8E 3HOVE 4BBRE 4A3FE 2JA8E 3S16E 4XSXE 1TWCE 4XLNE 3S17F 5E17E 4G7HE 3GTGE 3S1MF 2Y0SI 5IYBE 4MEYE 3S15E 4A3CE 3PO2E 2Y0SH 3EQLE 4XSZE 2B63E 3S1NE 1TWFF 3H0GE 4A3JF 4Y7NE 3GTLE 2A6EE 5FLMF 2R93F 5M5WE 3S2HE 4A3DE 1QKLA 3PO3F 4C3JE 4Q5SE 2PMZK 2WB1I 4G7OE 5IPLE 4A3IF 4A3GE 5IYCE 4LJZE 2WB1H 5C3EF 1I6HE 5C4XF 2E2JF 1IW7E 4A93E 3I4ME 4BY7E 4G7ZE 3HOYF 1TWAF 5D4DE 1I3QF 5C44E 3I4NE 1R9TF 4OIQE 2R92F 1Y1WF 5M3ME 3S17E 1WCMF 4BY1F 4A3EF 2NVTF 3S1ME 2E2IF 3HKZH 3WODE 5TMFE 3HOXF 4LK0E 3HOZF 3S1QF 1ZYRE 4MEXE 2YU9F 1TWFE 4A3JE 4YFNE 3RZDE 1SFOF 5FLME 2R93E 3M4OF 5M5YE 4AYBH 4OIPE 4BBSF 3GTKF 2JA7F 1I50F 3PO3E 4KN4E 4A3KF 3GTJF 4YFKE 3S14F 2A6HE 4A3IE 4C3HF 5C3EE 3H3VF 5C4XE 1TWGF 3DXJE 5M5XF 2E2JE 5M3FF 2JA6E 4Y52F 3HOYE 3GTQF 1I3QE 4C3IF 1R9TE
chains in the Genus database with same CATH topology
3GTOE 2R92E 1Y1WE 2NVTE 1WCME 4A3EE 4BY1E 2E2IE 1EIKA 1Y1VE 3HOZE 3HOXE 3S1QE 2YU9E 1SFOE 3M4OE 2JA7E 4A3KE 3GTJE 3S14E 4C3HE 1TWGE 5M5XE 4Y52E 3GTQE 4C3IE 5C4JE 2NVXE 3K7AE 2WAQH 3M3YE 1TWAE 4A3BE 4QIWH 3S1RE 3HOWE 4BXXE 4BBSE 3GTME 3GTKE 2JA5E 4C2ME 1I50E 4A3ME 4A3LE 5M3FE 5IYDE 2VUME 3S2DE 5IP9E 5IP7E 3GTPE 1DZFA 1K83E 3HOUE 3CQZE 2NVQE 1TWHE 2PMZH 2E2HE 4X6AE 3RZOE 2NVYE 2R7ZE 3FKIE 5FJ8E 3HOVE 4BBRE 4A3FE 2JA8E 3S16E 1TWCE 3GTGE 5IYBE 3S15E 4A3CE 3PO2E 2Y0SH 2B63E 3S1NE 3H0GE 4Y7NE 3GTLE 5M5WE 3S2HE 4A3DE 4C3JE 4A3GE 5IYCE 2WB1H 1I6HE 4A93E 3I4ME 4BY7E 5C44E 3I4NE 5M3ME 3S17E 3S1ME 3HKZH 1TWFE 4A3JE 3RZDE 5FLME 2R93E 5M5YE 4AYBH 3PO3E 4A3IE 5C3EE 3H3VF 5C4XE 2E2JE 2JA6E 3HOYE 1I3QE 1R9TE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTO E;  2R92 E;  1Y1W E;  2NVT E;  1WCM E;  4A3E E;  4BY1 E;  2E2I E;  1EIK A;  1Y1V E;  3HOZ E;  3HOX E;  3S1Q E;  2YU9 E;  1SFO E;  3M4O E;  2JA7 E;  4A3K E;  3GTJ E;  3S14 E;  4C3H E;  1TWG E;  5M5X E;  4Y52 E;  3GTQ E;  4C3I E;  5C4J E;  2NVX E;  3K7A E;  2WAQ H;  3M3Y E;  1TWA E;  4A3B E;  4QIW H;  3S1R E;  3HOW E;  4BXX E;  4BBS E;  3GTM E;  3GTK E;  2JA5 E;  4C2M E;  1I50 E;  4A3M E;  4A3L E;  5M3F E;  5IYD E;  2VUM E;  3S2D E;  5IP9 E;  5IP7 E;  3GTP E;  1DZF A;  1K83 E;  3HOU E;  3CQZ E;  2NVQ E;  1TWH E;  2PMZ H;  2E2H E;  4X6A E;  3RZO E;  2NVY E;  2R7Z E;  3FKI E;  5FJ8 E;  3HOV E;  4BBR E;  4A3F E;  2JA8 E;  3S16 E;  1TWC E;  3GTG E;  5IYB E;  3S15 E;  4A3C E;  3PO2 E;  2Y0S H;  2B63 E;  3S1N E;  3H0G E;  4Y7N E;  3GTL E;  5M5W E;  3S2H E;  4A3D E;  4C3J E;  4A3G E;  5IYC E;  2WB1 H;  1I6H E;  4A93 E;  3I4M E;  4BY7 E;  5C44 E;  3I4N E;  5M3M E;  3S17 E;  3S1M E;  3HKZ H;  1TWF E;  4A3J E;  3RZD E;  5FLM E;  2R93 E;  5M5Y E;  4AYB H;  3PO3 E;  4A3I E;  5C3E E;  3H3V F;  5C4X E;  2E2J E;  2JA6 E;  3HOY E;  1I3Q E;  1R9T E; 
#chains in the Genus database with same CATH topology
 2NVX F;  2CW0 E;  3GTO E;  2R92 E;  1Y1W E;  2NVT E;  1WCM E;  4A3E E;  4BY1 E;  3K7A F;  2E2I E;  4Q4Z E;  1EIK A;  1Y1V E;  3HOZ E;  3HOX E;  3M3Y F;  2O5J E;  3HKZ K;  4A3B F;  3S1Q E;  2YU9 E;  1SFO E;  3M4O E;  3S1R F;  4YFX E;  2E2H F;  3HOW F;  4BXX F;  2JA7 E;  4OIO E;  4AYB K;  4A3K E;  3GTJ E;  3S14 E;  4C3H E;  1TWG E;  5M5X E;  2A68 E;  4Y52 E;  4LK1 E;  2O5I E;  3GTM F;  3GTQ E;  2JA5 F;  4C2M F;  4C3I E;  5C4J E;  4YG2 E;  4ZH4 E;  2PPB E;  2NVX E;  3S16 F;  2BE5 E;  4MQ9 E;  4A3M F;  3K7A E;  4A3L F;  2WAQ H;  5IYD F;  2VUM F;  3M3Y E;  5IP9 F;  1TWA E;  4JK1 E;  3S2D F;  4A3B E;  4QIW H;  4XLP E;  3H3V G;  5TMC E;  3S1R E;  3HOW E;  3HOV F;  4BXX E;  5IP7 F;  4A3G F;  2KRX A;  3GTP F;  1I6H F;  1K83 F;  3HOU F;  5C4J F;  4KMU E;  3CQZ F;  2NVQ F;  1TWH F;  4BBS E;  4X6A F;  3GTM E;  3GTK E;  2JA5 E;  4C2M E;  1I50 E;  5M3M F;  1SMY E;  2NVY F;  2R7Z F;  3RZO F;  5D4C E;  4A3M E;  5BYH E;  3FKI F;  4A3L E;  5M3F E;  1YNN K;  5IYD E;  2WAQ K;  2VUM E;  3S2D E;  5IP9 E;  4BBR F;  5FJ8 F;  4A3F F;  1TWC F;  5D4E E;  5M5Y F;  3RZD F;  2JA8 F;  4QIW K;  3GTG F;  2A69 E;  5IYB F;  1HQM E;  3S15 F;  4A3C F;  3PO2 F;  5IP7 E;  2B63 F;  4OIR E;  3S1N F;  3GTP E;  3H0G F;  1DZF A;  1K83 E;  3HOU E;  4Y7N F;  4OIN E;  2JA6 F;  3GTL F;  3CQZ E;  5M5W F;  2NVQ E;  1TWH E;  3S2H F;  4A3D F;  2PMZ H;  4C3J F;  2E2H E;  4X6A E;  1YNJ K;  3GTO F;  3RZO E;  2NVY E;  2R7Z E;  4KN7 E;  5IYC F;  5E18 E;  4GZY E;  4LLG E;  4A93 F;  4BY7 F;  3I4M F;  3FKI E;  1Y1V F;  5C44 F;  3I4N F;  1I6V E;  5FJ8 E;  3HOV E;  4BBR E;  4A3F E;  2JA8 E;  3S16 E;  4XSX E;  1TWC E;  4XLN E;  3S17 F;  5E17 E;  4G7H E;  3GTG E;  3S1M F;  2Y0S I;  5IYB E;  4MEY E;  3S15 E;  4A3C E;  3PO2 E;  2Y0S H;  3EQL E;  4XSZ E;  2B63 E;  3S1N E;  1TWF F;  3H0G E;  4A3J F;  4Y7N E;  3GTL E;  2A6E E;  5FLM F;  2R93 F;  5M5W E;  3S2H E;  4A3D E;  1QKL A;  3PO3 F;  4C3J E;  4Q5S E;  2PMZ K;  2WB1 I;  4G7O E;  5IPL E;  4A3I F;  4A3G E;  5IYC E;  4LJZ E;  2WB1 H;  5C3E F;  1I6H E;  5C4X F;  2E2J F;  1IW7 E;  4A93 E;  3I4M E;  4BY7 E;  4G7Z E;  3HOY F;  1TWA F;  5D4D E;  1I3Q F;  5C44 E;  3I4N E;  1R9T F;  4OIQ E;  2R92 F;  1Y1W F;  5M3M E;  3S17 E;  1WCM F;  4BY1 F;  4A3E F;  2NVT F;  3S1M E;  2E2I F;  3HKZ H;  3WOD E;  5TMF E;  3HOX F;  4LK0 E;  3HOZ F;  3S1Q F;  1ZYR E;  4MEX E;  2YU9 F;  1TWF E;  4A3J E;  4YFN E;  3RZD E;  1SFO F;  5FLM E;  2R93 E;  3M4O F;  5M5Y E;  4AYB H;  4OIP E;  4BBS F;  3GTK F;  2JA7 F;  1I50 F;  3PO3 E;  4KN4 E;  4A3K F;  3GTJ F;  4YFK E;  3S14 F;  2A6H E;  4A3I E;  4C3H F;  5C3E E;  3H3V F;  5C4X E;  1TWG F;  3DXJ E;  5M5X F;  2E2J E;  5M3F F;  2JA6 E;  4Y52 F;  3HOY E;  3GTQ F;  1I3Q E;  4C3I F;  1R9T E; 
#chains in the Genus database with same CATH homology
 3GTO E;  2R92 E;  1Y1W E;  2NVT E;  1WCM E;  4A3E E;  4BY1 E;  2E2I E;  1EIK A;  1Y1V E;  3HOZ E;  3HOX E;  3S1Q E;  2YU9 E;  1SFO E;  3M4O E;  2JA7 E;  4A3K E;  3GTJ E;  3S14 E;  4C3H E;  1TWG E;  5M5X E;  4Y52 E;  3GTQ E;  4C3I E;  5C4J E;  2NVX E;  3K7A E;  2WAQ H;  3M3Y E;  1TWA E;  4A3B E;  4QIW H;  3S1R E;  3HOW E;  4BXX E;  4BBS E;  3GTM E;  3GTK E;  2JA5 E;  4C2M E;  1I50 E;  4A3M E;  4A3L E;  5M3F E;  5IYD E;  2VUM E;  3S2D E;  5IP9 E;  5IP7 E;  3GTP E;  1DZF A;  1K83 E;  3HOU E;  3CQZ E;  2NVQ E;  1TWH E;  2PMZ H;  2E2H E;  4X6A E;  3RZO E;  2NVY E;  2R7Z E;  3FKI E;  5FJ8 E;  3HOV E;  4BBR E;  4A3F E;  2JA8 E;  3S16 E;  1TWC E;  3GTG E;  5IYB E;  3S15 E;  4A3C E;  3PO2 E;  2Y0S H;  2B63 E;  3S1N E;  3H0G E;  4Y7N E;  3GTL E;  5M5W E;  3S2H E;  4A3D E;  4C3J E;  4A3G E;  5IYC E;  2WB1 H;  1I6H E;  4A93 E;  3I4M E;  4BY7 E;  5C44 E;  3I4N E;  5M3M E;  3S17 E;  3S1M E;  3HKZ H;  1TWF E;  4A3J E;  3RZD E;  5FLM E;  2R93 E;  5M5Y E;  4AYB H;  3PO3 E;  4A3I E;  5C3E E;  3H3V F;  5C4X E;  2E2J E;  2JA6 E;  3HOY E;  1I3Q E;  1R9T E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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