5M5WE

Rna polymerase i open complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 46
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5m5wE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5m5wE02
4A3GE 4BBRE 5FLME 3K7AE 3GTQE 4A3IE 2E2JE 3HOYE 1WCME 2WAQH 3I4ME 5M3ME 4A3FE 1SFOE 3HOWE 4C3JE 3GTKE 5IYDE 2B63E 1TWGE 5C4XE 2NVQE 3CQZE 3FKIE 3H0GE 3I4NE 2NVYE 3RZDE 2R7ZE 1Y1VE 4Y7NE 2Y0SH 3GTLE 3GTOE 3HKZH 4AYBH 3S2DE 2YU9E 1K83E 3RZOE 3S17E 4X6AE 1TWAE 5FJ8E 3S1QE 5IP7E 3HOZE 2WB1H 4BBSE 2R93E 4A3EE 3PO2E 3HOUE 5M3FE 4C2ME 5IYBE 4A3LE 5M5WE 5M5YE 4BY7E 3S15E 1TWFE 3GTJE 3H3VF 5C3EE 4A3KE 1DZFA 2NVTE 4BY1E 4QIWH 2JA8E 3M3YE 5IP9E 3S1ME 2NVXE 1I6HE 2JA5E 1I3QE 3S14E 3GTPE 3HOVE 4A3CE 4Y52E 5M5XE 4A3ME 2PMZH 1EIKA 2JA7E 2VUME 3S16E 4A93E 3S1NE 2R92E 4A3BE 5C44E 1Y1WE 2E2IE 4C3IE 2JA6E 2E2HE 4BXXE 1R9TE 1I50E 4A3DE 1TWCE 1TWHE 3GTGE 3PO3E 3S1RE 3S2HE 3HOXE 3GTME 5IYCE 4C3HE 3M4OE 5C4JE 4A3JE
chains in the Genus database with same CATH superfamily
3EQLE 4A3GE 4XSXE 4BBRE 3H0GF 3WODE 5FLMF 4MQ9E 3I4NF 3K7AF 5FLME 2A6HE 5TMFE 4A3IF 3RZDF 3K7AE 3GTQE 2E2JF 3HOYF 4A3IE 3GTOF 2E2JE 3HOYE 4YG2E 1WCME 3S2DF 2YU9F 4OIPE 4G7ZE 1K83F 3RZOF 1TWAF 2WAQH 4XLNE 3I4ME 3S1QF 3HOZF 4Q4ZE 4LJZE 4A3GF 5M3ME 2O5IE 4BBSF 4XSZE 4A3EF 1SFOF 4A3FE 3HOUF 4C2MF 4C3JF 1SFOE 1IW7E 2Y0SI 4GZYE 3HOWE 3GTKF 4C3JE 2B63F 3GTKE 1TWGF 5IYDE 2NVQF 4KN4E 2B63E 5M5YF 3CQZF 3FKIF 1TWGE 5C4XE 4LK0E 2NVQE 3CQZE 3FKIE 2O5JE 3HOWF 1ZYRE 3H0GE 2NVYF 2WB1I 2BE5E 4KN7E 3I4NE 2R7ZF 1Y1VF 2NVYE 1QKLA 4Y7NF 4G7OE 3RZDE 3GTLF 4Q5SE 2R7ZE 1Y1VE 4Y7NE 2Y0SH 3GTLE 3GTOE 3HKZH 4AYBH 3S2DE 3S17F 2YU9E 4X6AF 4LK1E 1K83E 3RZOE 3S17E 4X6AE 1TWAE 5IP7F 5FJ8F 2NVXF 5FJ8E 2R93F 3S1QE 5IP7E 3HOZE 2WB1H 3S14F 5D4DE 4BBSE 2R93E 4OINE 5M3FF 3GTPF 4A3EE 3H3VG 1HQME 3HOVF 3PO2F 4A3MF 3PO2E 4A3CF 3HOUE 5M3FE 5IYBF 4C2ME 3HKZK 1I6VE 4AYBK 5IYBE 4A3LF 2A6EE 3S16F 5M5WF 4A3LE 2WAQK 5M5WE 4BY7F 4YFKE 2R92F 5M5YE 4BY7E 3S15F 5C44F 1Y1WF 1TWFF 4OIRE 3S15E 2JA6F 2CW0E 1TWFE 3GTJF 4BXXF 5BYHE 2PPBE 3GTJE 5C3EF 4A3KF 5IPLE 2NVTF 3H3VF 4A3DF 5C3EE 4A3KE 4BY1F 1DZFA 2NVTE 3S1RF 2JA8F 3GTGF 4BY1E 3HOXF 3M3YF 3PO3F 4QIWH 2JA8E 5IP9F 3S1MF 3M3YE 1I6HF 5IP9E 2JA5F 3M4OF 1I3QF 3S1ME 2NVXE 1I6HE 2JA5E 1I3QE 3S14E 4JK1E 4BBRF 4Y52F 5M5XF 5E17E 3GTPE 3HOVE 4A3CE 4Y52E 5M5XE 4A3ME 2PMZH 5E18E 2JA7F 2VUMF 1EIKA 3GTQF 4A93F 2JA7E 4OIOE 2VUME 4YFXE 3S16E 3DXJE 4A93E 3S1NF 4QIWK 1WCMF 4A3BF 4MEYE 3S1NE 4XLPE 2R92E 5D4EE 2E2IF 4A3BE 4C3IF 5C44E 1Y1WE 2E2IE 2E2HF 4C3IE 3I4MF 4LLGE 2JA6E 2E2HE 1YNNK 4BXXE 2PMZK 5M3MF 5TMCE 4ZH4E 1I50F 1R9TF 4KMUE 1R9TE 4A3FF 1I50E 4OIQE 4G7HE 1TWCF 1TWHF 5D4CE 4A3DE 4YFNE 3S2HF 1YNJK 3GTMF 1TWCE 1TWHE 4MEXE 3GTGE 3PO3E 3S1RE 3S2HE 2A68E 2A69E 3HOXE 3GTME 4C3HF 5IYCF 5IYCE 1SMYE 5IYDF 5C4JF 4A3JF 4C3HE 2KRXA 5C4XF 3M4OE 5C4JE 4A3JE
chains in the Genus database with same CATH topology
4A3GE 4BBRE 5FLME 3K7AE 3GTQE 4A3IE 2E2JE 3HOYE 1WCME 2WAQH 3I4ME 5M3ME 4A3FE 1SFOE 3HOWE 4C3JE 3GTKE 5IYDE 2B63E 1TWGE 5C4XE 2NVQE 3CQZE 3FKIE 3H0GE 3I4NE 2NVYE 3RZDE 2R7ZE 1Y1VE 4Y7NE 2Y0SH 3GTLE 3GTOE 3HKZH 4AYBH 3S2DE 2YU9E 1K83E 3RZOE 3S17E 4X6AE 1TWAE 5FJ8E 3S1QE 5IP7E 3HOZE 2WB1H 4BBSE 2R93E 4A3EE 3PO2E 3HOUE 5M3FE 4C2ME 5IYBE 4A3LE 5M5WE 5M5YE 4BY7E 3S15E 1TWFE 3GTJE 3H3VF 5C3EE 4A3KE 1DZFA 2NVTE 4BY1E 4QIWH 2JA8E 3M3YE 5IP9E 3S1ME 2NVXE 1I6HE 2JA5E 1I3QE 3S14E 3GTPE 3HOVE 4A3CE 4Y52E 5M5XE 4A3ME 2PMZH 1EIKA 2JA7E 2VUME 3S16E 4A93E 3S1NE 2R92E 4A3BE 5C44E 1Y1WE 2E2IE 4C3IE 2JA6E 2E2HE 4BXXE 1R9TE 1I50E 4A3DE 1TWCE 1TWHE 3GTGE 3PO3E 3S1RE 3S2HE 3HOXE 3GTME 5IYCE 4C3HE 3M4OE 5C4JE 4A3JE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3G E;  4BBR E;  5FLM E;  3K7A E;  3GTQ E;  4A3I E;  2E2J E;  3HOY E;  1WCM E;  2WAQ H;  3I4M E;  5M3M E;  4A3F E;  1SFO E;  3HOW E;  4C3J E;  3GTK E;  5IYD E;  2B63 E;  1TWG E;  5C4X E;  2NVQ E;  3CQZ E;  3FKI E;  3H0G E;  3I4N E;  2NVY E;  3RZD E;  2R7Z E;  1Y1V E;  4Y7N E;  2Y0S H;  3GTL E;  3GTO E;  3HKZ H;  4AYB H;  3S2D E;  2YU9 E;  1K83 E;  3RZO E;  3S17 E;  4X6A E;  1TWA E;  5FJ8 E;  3S1Q E;  5IP7 E;  3HOZ E;  2WB1 H;  4BBS E;  2R93 E;  4A3E E;  3PO2 E;  3HOU E;  5M3F E;  4C2M E;  5IYB E;  4A3L E;  5M5W E;  5M5Y E;  4BY7 E;  3S15 E;  1TWF E;  3GTJ E;  3H3V F;  5C3E E;  4A3K E;  1DZF A;  2NVT E;  4BY1 E;  4QIW H;  2JA8 E;  3M3Y E;  5IP9 E;  3S1M E;  2NVX E;  1I6H E;  2JA5 E;  1I3Q E;  3S14 E;  3GTP E;  3HOV E;  4A3C E;  4Y52 E;  5M5X E;  4A3M E;  2PMZ H;  1EIK A;  2JA7 E;  2VUM E;  3S16 E;  4A93 E;  3S1N E;  2R92 E;  4A3B E;  5C44 E;  1Y1W E;  2E2I E;  4C3I E;  2JA6 E;  2E2H E;  4BXX E;  1R9T E;  1I50 E;  4A3D E;  1TWC E;  1TWH E;  3GTG E;  3PO3 E;  3S1R E;  3S2H E;  3HOX E;  3GTM E;  5IYC E;  4C3H E;  3M4O E;  5C4J E;  4A3J E; 
#chains in the Genus database with same CATH topology
 3EQL E;  4A3G E;  4XSX E;  4BBR E;  3H0G F;  3WOD E;  5FLM F;  4MQ9 E;  3I4N F;  3K7A F;  5FLM E;  2A6H E;  5TMF E;  4A3I F;  3RZD F;  3K7A E;  3GTQ E;  2E2J F;  3HOY F;  4A3I E;  3GTO F;  2E2J E;  3HOY E;  4YG2 E;  1WCM E;  3S2D F;  2YU9 F;  4OIP E;  4G7Z E;  1K83 F;  3RZO F;  1TWA F;  2WAQ H;  4XLN E;  3I4M E;  3S1Q F;  3HOZ F;  4Q4Z E;  4LJZ E;  4A3G F;  5M3M E;  2O5I E;  4BBS F;  4XSZ E;  4A3E F;  1SFO F;  4A3F E;  3HOU F;  4C2M F;  4C3J F;  1SFO E;  1IW7 E;  2Y0S I;  4GZY E;  3HOW E;  3GTK F;  4C3J E;  2B63 F;  3GTK E;  1TWG F;  5IYD E;  2NVQ F;  4KN4 E;  2B63 E;  5M5Y F;  3CQZ F;  3FKI F;  1TWG E;  5C4X E;  4LK0 E;  2NVQ E;  3CQZ E;  3FKI E;  2O5J E;  3HOW F;  1ZYR E;  3H0G E;  2NVY F;  2WB1 I;  2BE5 E;  4KN7 E;  3I4N E;  2R7Z F;  1Y1V F;  2NVY E;  1QKL A;  4Y7N F;  4G7O E;  3RZD E;  3GTL F;  4Q5S E;  2R7Z E;  1Y1V E;  4Y7N E;  2Y0S H;  3GTL E;  3GTO E;  3HKZ H;  4AYB H;  3S2D E;  3S17 F;  2YU9 E;  4X6A F;  4LK1 E;  1K83 E;  3RZO E;  3S17 E;  4X6A E;  1TWA E;  5IP7 F;  5FJ8 F;  2NVX F;  5FJ8 E;  2R93 F;  3S1Q E;  5IP7 E;  3HOZ E;  2WB1 H;  3S14 F;  5D4D E;  4BBS E;  2R93 E;  4OIN E;  5M3F F;  3GTP F;  4A3E E;  3H3V G;  1HQM E;  3HOV F;  3PO2 F;  4A3M F;  3PO2 E;  4A3C F;  3HOU E;  5M3F E;  5IYB F;  4C2M E;  3HKZ K;  1I6V E;  4AYB K;  5IYB E;  4A3L F;  2A6E E;  3S16 F;  5M5W F;  4A3L E;  2WAQ K;  5M5W E;  4BY7 F;  4YFK E;  2R92 F;  5M5Y E;  4BY7 E;  3S15 F;  5C44 F;  1Y1W F;  1TWF F;  4OIR E;  3S15 E;  2JA6 F;  2CW0 E;  1TWF E;  3GTJ F;  4BXX F;  5BYH E;  2PPB E;  3GTJ E;  5C3E F;  4A3K F;  5IPL E;  2NVT F;  3H3V F;  4A3D F;  5C3E E;  4A3K E;  4BY1 F;  1DZF A;  2NVT E;  3S1R F;  2JA8 F;  3GTG F;  4BY1 E;  3HOX F;  3M3Y F;  3PO3 F;  4QIW H;  2JA8 E;  5IP9 F;  3S1M F;  3M3Y E;  1I6H F;  5IP9 E;  2JA5 F;  3M4O F;  1I3Q F;  3S1M E;  2NVX E;  1I6H E;  2JA5 E;  1I3Q E;  3S14 E;  4JK1 E;  4BBR F;  4Y52 F;  5M5X F;  5E17 E;  3GTP E;  3HOV E;  4A3C E;  4Y52 E;  5M5X E;  4A3M E;  2PMZ H;  5E18 E;  2JA7 F;  2VUM F;  1EIK A;  3GTQ F;  4A93 F;  2JA7 E;  4OIO E;  2VUM E;  4YFX E;  3S16 E;  3DXJ E;  4A93 E;  3S1N F;  4QIW K;  1WCM F;  4A3B F;  4MEY E;  3S1N E;  4XLP E;  2R92 E;  5D4E E;  2E2I F;  4A3B E;  4C3I F;  5C44 E;  1Y1W E;  2E2I E;  2E2H F;  4C3I E;  3I4M F;  4LLG E;  2JA6 E;  2E2H E;  1YNN K;  4BXX E;  2PMZ K;  5M3M F;  5TMC E;  4ZH4 E;  1I50 F;  1R9T F;  4KMU E;  1R9T E;  4A3F F;  1I50 E;  4OIQ E;  4G7H E;  1TWC F;  1TWH F;  5D4C E;  4A3D E;  4YFN E;  3S2H F;  1YNJ K;  3GTM F;  1TWC E;  1TWH E;  4MEX E;  3GTG E;  3PO3 E;  3S1R E;  3S2H E;  2A68 E;  2A69 E;  3HOX E;  3GTM E;  4C3H F;  5IYC F;  5IYC E;  1SMY E;  5IYD F;  5C4J F;  4A3J F;  4C3H E;  2KRX A;  5C4X F;  3M4O E;  5C4J E;  4A3J E; 
#chains in the Genus database with same CATH homology
 4A3G E;  4BBR E;  5FLM E;  3K7A E;  3GTQ E;  4A3I E;  2E2J E;  3HOY E;  1WCM E;  2WAQ H;  3I4M E;  5M3M E;  4A3F E;  1SFO E;  3HOW E;  4C3J E;  3GTK E;  5IYD E;  2B63 E;  1TWG E;  5C4X E;  2NVQ E;  3CQZ E;  3FKI E;  3H0G E;  3I4N E;  2NVY E;  3RZD E;  2R7Z E;  1Y1V E;  4Y7N E;  2Y0S H;  3GTL E;  3GTO E;  3HKZ H;  4AYB H;  3S2D E;  2YU9 E;  1K83 E;  3RZO E;  3S17 E;  4X6A E;  1TWA E;  5FJ8 E;  3S1Q E;  5IP7 E;  3HOZ E;  2WB1 H;  4BBS E;  2R93 E;  4A3E E;  3PO2 E;  3HOU E;  5M3F E;  4C2M E;  5IYB E;  4A3L E;  5M5W E;  5M5Y E;  4BY7 E;  3S15 E;  1TWF E;  3GTJ E;  3H3V F;  5C3E E;  4A3K E;  1DZF A;  2NVT E;  4BY1 E;  4QIW H;  2JA8 E;  3M3Y E;  5IP9 E;  3S1M E;  2NVX E;  1I6H E;  2JA5 E;  1I3Q E;  3S14 E;  3GTP E;  3HOV E;  4A3C E;  4Y52 E;  5M5X E;  4A3M E;  2PMZ H;  1EIK A;  2JA7 E;  2VUM E;  3S16 E;  4A93 E;  3S1N E;  2R92 E;  4A3B E;  5C44 E;  1Y1W E;  2E2I E;  4C3I E;  2JA6 E;  2E2H E;  4BXX E;  1R9T E;  1I50 E;  4A3D E;  1TWC E;  1TWH E;  3GTG E;  3PO3 E;  3S1R E;  3S2H E;  3HOX E;  3GTM E;  5IYC E;  4C3H E;  3M4O E;  5C4J E;  4A3J E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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