5M5WF

Rna polymerase i open complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
100
structure length
100
Chain Sequence
PEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 25
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5m5wF00
4C3IF 3GTMF 4MEXE 5M5YF 4Q4ZE 5IYDF 2R7ZF 3HOUF 4A3EF 2JA8F 2CW0E 4YFKE 4OINE 5M3MF 5BYHE 4A3GF 2A69E 3S1QF 2BE5E 2A6EE 4GZYE 3M3YF 5E18E 3H3VG 3GTQF 4A93F 3GTOF 2E2HF 3PO2F 3FKIF 1YNJK 3S14F 3RZDF 4OIPE 5D4CE 3S15F 1TWFF 4C3HF 4OIOE 5FJ8F 1I3QF 3K7AF 3S1RF 5C4XF 2WAQK 4XLPE 2PMZK 4A3IF 4JK1E 5TMCE 3S1NF 2JA6F 1HQME 3GTPF 4LJZE 4YG2E 4LK0E 5E17E 3S1MF 2R93F 3DXJE 5D4DE 4BXXF 3PO3F 1TWGF 3HOYF 1K83F 5FLMF 5M3FF 4Q5SE 5IPLE 4XSZE 4ZH4E 1R9TF 4OIRE 2B63F 4A3MF 3RZOF 4Y52F 3HOXF 4A3CF 2PPBE 3S2HF 2WB1I 1SFOF 4KN4E 4BBSF 1WCMF 4MQ9E 4G7HE 2YU9F 3GTLF 5M5XF 5C3EF 2Y0SI 3S17F 3S16F 4Y7NF 2O5JE 3GTJF 4A3KF 4YFXE 3WODE 2E2IF 5C4JF 3GTGF 1YNNK 2A6HE 4MEYE 1I6HF 4OIQE 1TWCF 1I6VE 4YFNE 2NVQF 2R92F 2JA5F 5TMFE 2NVXF 4G7OE 3I4MF 3I4NF 4X6AF 1Y1WF 1ZYRE 5D4EE 1Y1VF 4A3JF 3EQLE 4A3BF 5IP9F 3HOVF 4KMUE 5C44F 4LLGE 5IYBF 3HOWF 4C3JF 3H0GF 2NVYF 1TWAF 5IP7F 4BY1F 2VUMF 2NVTF 2O5IE 3GTKF 5M5WF 3HOZF 4A3DF 4C2MF 1QKLA 4A3FF 4XSXE 3HKZK 4LK1E 4AYBK 1IW7E 1SMYE 4G7ZE 2JA7F 4A3LF 4KN7E 3M4OF 1I50F 4XLNE 3S2DF 2E2JF 4BY7F 2A68E 5IYCF 4BBRF 3CQZF 1TWHF
chains in the Genus database with same CATH superfamily
4A3EE 4C3IF 3GTMF 2JA8E 4MEXE 5M3ME 4A3GE 5M5YF 4Q4ZE 3S1QE 5IYDF 3HOYE 2R7ZF 3S17F 3HOUF 4A3EF 2JA8F 1EIKA 2CW0E 3GTQE 4YFKE 4OINE 5M3MF 5BYHE 3GTOE 4A93E 2A69E 2E2HE 3S1QF 4A3GF 2BE5E 2A6EE 3PO2E 3FKIE 3S14E 4GZYE 3RZDE 3M3YF 5E18E 3S15E 1TWFE 4C3HE 3H3VG 3GTQF 2WB1H 5FJ8E 3GTOF 1I3QE 3S1RE 2E2HF 4A93F 2YU9E 5C4XE 3PO2F 3FKIF 1YNJK 3S14F 4A3IE 3S1NE 3RZDF 2Y0SH 4OIPE 5D4CE 2JA6E 3GTPE 3S15F 1TWFF 4C3HF 4OIOE 3HKZH 3S1ME 5FJ8F 2R93E 1I3QF 3K7AF 3S1RF 4BXXE 2WAQK 4XLPE 3PO3E 5C4XF 2PMZK 4A3IF 4JK1E 5TMCE 3S1NF 2JA6F 1HQME 3GTPF 1K83E 5FLME 4LJZE 5M3FE 4YG2E 4LK0E 5E17E 3S1MF 2R93F 3DXJE 4BBRF 1R9TE 5D4DE 2B63E 4BXXF 3PO3F 4A3LF 2R92E 4A3ME 3HOYF 1K83F 5FLMF 5M3FF 4Q5SE 3RZOE 4Y52E 5IPLE 4XSZE 3HOXE 4A3CE 4ZH4E 3S2HE 1R9TF 1SFOE 4OIRE 2B63F 4BBSE 1WCME 4A3MF 3GTLE 3S17E 5M5XE 5C3EE 3RZOF 3S16E 4Y7NE 4Y52F 3GTJE 4A3KE 3HOXF 4A3CF 2E2IE 5C4JE 2PPBE 3GTGE 3S2HF 4QIWH 2WB1I 1SFOF 1I6HE 4KN4E 4AYBH 4BBSF 1WCMF 1TWCE 4MQ9E 2NVQE 4G7HE 2YU9F 1DZFA 5M5XF 5C3EF 2Y0SI 2JA5E 3GTLF 3S16F 4Y7NF 2O5JE 2NVXE 3GTJF 4A3KF 4YFXE 3WODE 2E2IF 5C4JF 3GTGF 3I4ME 1YNNK 2A6HE 3I4NE 4MEYE 1I6HF 4X6AE 1Y1WE 4OIQE 1TWCF 1I6VE 4YFNE 2KRXA 2NVQF 2R92F 2JA5F 5TMFE 2NVXF 1Y1VE 4G7OE 4A3JE 3I4MF 4A3BE 3I4NF 5IP9E 4X6AF 1Y1WF 3HOVE 1ZYRE 5C44E 5IYBE 3HOWE 4C3JE 3H0GE 5D4EE 2NVYE 1Y1VF 4A3JF 3H3VF 1TWAE 3EQLE 4A3BF 5IP7E 4BY1E 2VUME 2NVTE 3HOUE 5IP9F 3HOVF 4KMUE 5C44F 4LLGE 5M5WE 3GTKE 5IYBF 3HOWF 4A3DE 4C2ME 3HOZE 4C3JF 3H0GF 4A3FE 2NVYF 3M3YE 4A3LE 2JA7E 1TWAF 5IP7F 4BY1F 2VUMF 2NVTF 2O5IE 3M4OE 1I50E 3S2DE 3GTKF 5M5WF 2E2JE 3HOZF 4A3DF 4QIWK 4C2MF 1QKLA 4BY7E 4A3FF 4XSXE 3HKZK 1TWGE 3CQZE 1IW7E 1SMYE 4LK1E 1TWHE 5IYCE 4AYBK 4KN7E 4BBRE 4G7ZE 2JA7F 4C3IE 3GTME 2WAQH 2PMZH 1I50F 3K7AE 4XLNE 3M4OF 3S2DF 2E2JF 5M5YE 4BY7F 5IYDE 2R7ZE 2A68E 5IYCF 1TWGF 3CQZF 1TWHF
chains in the Genus database with same CATH topology
4C3IF 3GTMF 4MEXE 5M5YF 4Q4ZE 5IYDF 2R7ZF 3HOUF 4A3EF 2JA8F 2CW0E 4YFKE 4OINE 5M3MF 5BYHE 4A3GF 2A69E 3S1QF 2BE5E 2A6EE 4GZYE 3M3YF 5E18E 3H3VG 3GTQF 4A93F 3GTOF 2E2HF 3PO2F 3FKIF 1YNJK 3S14F 3RZDF 4OIPE 5D4CE 3S15F 1TWFF 4C3HF 4OIOE 5FJ8F 1I3QF 3K7AF 3S1RF 5C4XF 2WAQK 4XLPE 2PMZK 4A3IF 4JK1E 5TMCE 3S1NF 2JA6F 1HQME 3GTPF 4LJZE 4YG2E 4LK0E 5E17E 3S1MF 2R93F 3DXJE 5D4DE 4BXXF 3PO3F 1TWGF 3HOYF 1K83F 5FLMF 5M3FF 4Q5SE 5IPLE 4XSZE 4ZH4E 1R9TF 4OIRE 2B63F 4A3MF 3RZOF 4Y52F 3HOXF 4A3CF 2PPBE 3S2HF 2WB1I 1SFOF 4KN4E 4BBSF 1WCMF 4MQ9E 4G7HE 2YU9F 3GTLF 5M5XF 5C3EF 2Y0SI 3S17F 3S16F 4Y7NF 2O5JE 3GTJF 4A3KF 4YFXE 3WODE 2E2IF 5C4JF 3GTGF 1YNNK 2A6HE 4MEYE 1I6HF 4OIQE 1TWCF 1I6VE 4YFNE 2KRXA 2NVQF 2R92F 2JA5F 5TMFE 2NVXF 4G7OE 3I4MF 3I4NF 4X6AF 1Y1WF 1ZYRE 5D4EE 1Y1VF 4A3JF 3EQLE 4A3BF 5IP9F 3HOVF 4KMUE 5C44F 4LLGE 5IYBF 3HOWF 4C3JF 3H0GF 2NVYF 1TWAF 5IP7F 4BY1F 2VUMF 2NVTF 2O5IE 3GTKF 5M5WF 3HOZF 4A3DF 4QIWK 4C2MF 1QKLA 4A3FF 4XSXE 3HKZK 4LK1E 4AYBK 1IW7E 1SMYE 4G7ZE 2JA7F 4A3LF 4KN7E 3M4OF 1I50F 4XLNE 3S2DF 2E2JF 4BY7F 2A68E 5IYCF 4BBRF 3CQZF 1TWHF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3I F;  3GTM F;  4MEX E;  5M5Y F;  4Q4Z E;  5IYD F;  2R7Z F;  3HOU F;  4A3E F;  2JA8 F;  2CW0 E;  4YFK E;  4OIN E;  5M3M F;  5BYH E;  4A3G F;  2A69 E;  3S1Q F;  2BE5 E;  2A6E E;  4GZY E;  3M3Y F;  5E18 E;  3H3V G;  3GTQ F;  4A93 F;  3GTO F;  2E2H F;  3PO2 F;  3FKI F;  1YNJ K;  3S14 F;  3RZD F;  4OIP E;  5D4C E;  3S15 F;  1TWF F;  4C3H F;  4OIO E;  5FJ8 F;  1I3Q F;  3K7A F;  3S1R F;  5C4X F;  2WAQ K;  4XLP E;  2PMZ K;  4A3I F;  4JK1 E;  5TMC E;  3S1N F;  2JA6 F;  1HQM E;  3GTP F;  4LJZ E;  4YG2 E;  4LK0 E;  5E17 E;  3S1M F;  2R93 F;  3DXJ E;  5D4D E;  4BXX F;  3PO3 F;  1TWG F;  3HOY F;  1K83 F;  5FLM F;  5M3F F;  4Q5S E;  5IPL E;  4XSZ E;  4ZH4 E;  1R9T F;  4OIR E;  2B63 F;  4A3M F;  3RZO F;  4Y52 F;  3HOX F;  4A3C F;  2PPB E;  3S2H F;  2WB1 I;  1SFO F;  4KN4 E;  4BBS F;  1WCM F;  4MQ9 E;  4G7H E;  2YU9 F;  3GTL F;  5M5X F;  5C3E F;  2Y0S I;  3S17 F;  3S16 F;  4Y7N F;  2O5J E;  3GTJ F;  4A3K F;  4YFX E;  3WOD E;  2E2I F;  5C4J F;  3GTG F;  1YNN K;  2A6H E;  4MEY E;  1I6H F;  4OIQ E;  1TWC F;  1I6V E;  4YFN E;  2NVQ F;  2R92 F;  2JA5 F;  5TMF E;  2NVX F;  4G7O E;  3I4M F;  3I4N F;  4X6A F;  1Y1W F;  1ZYR E;  5D4E E;  1Y1V F;  4A3J F;  3EQL E;  4A3B F;  5IP9 F;  3HOV F;  4KMU E;  5C44 F;  4LLG E;  5IYB F;  3HOW F;  4C3J F;  3H0G F;  2NVY F;  1TWA F;  5IP7 F;  4BY1 F;  2VUM F;  2NVT F;  2O5I E;  3GTK F;  5M5W F;  3HOZ F;  4A3D F;  4C2M F;  1QKL A;  4A3F F;  4XSX E;  3HKZ K;  4LK1 E;  4AYB K;  1IW7 E;  1SMY E;  4G7Z E;  2JA7 F;  4A3L F;  4KN7 E;  3M4O F;  1I50 F;  4XLN E;  3S2D F;  2E2J F;  4BY7 F;  2A68 E;  5IYC F;  4BBR F;  3CQZ F;  1TWH F; 
#chains in the Genus database with same CATH topology
 4A3E E;  4C3I F;  3GTM F;  2JA8 E;  4MEX E;  5M3M E;  4A3G E;  5M5Y F;  4Q4Z E;  3S1Q E;  5IYD F;  3HOY E;  2R7Z F;  3S17 F;  3HOU F;  4A3E F;  2JA8 F;  1EIK A;  2CW0 E;  3GTQ E;  4YFK E;  4OIN E;  5M3M F;  5BYH E;  3GTO E;  4A93 E;  2A69 E;  2E2H E;  3S1Q F;  4A3G F;  2BE5 E;  2A6E E;  3PO2 E;  3FKI E;  3S14 E;  4GZY E;  3RZD E;  3M3Y F;  5E18 E;  3S15 E;  1TWF E;  4C3H E;  3H3V G;  3GTQ F;  2WB1 H;  5FJ8 E;  3GTO F;  1I3Q E;  3S1R E;  2E2H F;  4A93 F;  2YU9 E;  5C4X E;  3PO2 F;  3FKI F;  1YNJ K;  3S14 F;  4A3I E;  3S1N E;  3RZD F;  2Y0S H;  4OIP E;  5D4C E;  2JA6 E;  3GTP E;  3S15 F;  1TWF F;  4C3H F;  4OIO E;  3HKZ H;  3S1M E;  5FJ8 F;  2R93 E;  1I3Q F;  3K7A F;  3S1R F;  4BXX E;  2WAQ K;  4XLP E;  3PO3 E;  5C4X F;  2PMZ K;  4A3I F;  4JK1 E;  5TMC E;  3S1N F;  2JA6 F;  1HQM E;  3GTP F;  1K83 E;  5FLM E;  4LJZ E;  5M3F E;  4YG2 E;  4LK0 E;  5E17 E;  3S1M F;  2R93 F;  3DXJ E;  4BBR F;  1R9T E;  5D4D E;  2B63 E;  4BXX F;  3PO3 F;  4A3L F;  2R92 E;  4A3M E;  3HOY F;  1K83 F;  5FLM F;  5M3F F;  4Q5S E;  3RZO E;  4Y52 E;  5IPL E;  4XSZ E;  3HOX E;  4A3C E;  4ZH4 E;  3S2H E;  1R9T F;  1SFO E;  4OIR E;  2B63 F;  4BBS E;  1WCM E;  4A3M F;  3GTL E;  3S17 E;  5M5X E;  5C3E E;  3RZO F;  3S16 E;  4Y7N E;  4Y52 F;  3GTJ E;  4A3K E;  3HOX F;  4A3C F;  2E2I E;  5C4J E;  2PPB E;  3GTG E;  3S2H F;  4QIW H;  2WB1 I;  1SFO F;  1I6H E;  4KN4 E;  4AYB H;  4BBS F;  1WCM F;  1TWC E;  4MQ9 E;  2NVQ E;  4G7H E;  2YU9 F;  1DZF A;  5M5X F;  5C3E F;  2Y0S I;  2JA5 E;  3GTL F;  3S16 F;  4Y7N F;  2O5J E;  2NVX E;  3GTJ F;  4A3K F;  4YFX E;  3WOD E;  2E2I F;  5C4J F;  3GTG F;  3I4M E;  1YNN K;  2A6H E;  3I4N E;  4MEY E;  1I6H F;  4X6A E;  1Y1W E;  4OIQ E;  1TWC F;  1I6V E;  4YFN E;  2KRX A;  2NVQ F;  2R92 F;  2JA5 F;  5TMF E;  2NVX F;  1Y1V E;  4G7O E;  4A3J E;  3I4M F;  4A3B E;  3I4N F;  5IP9 E;  4X6A F;  1Y1W F;  3HOV E;  1ZYR E;  5C44 E;  5IYB E;  3HOW E;  4C3J E;  3H0G E;  5D4E E;  2NVY E;  1Y1V F;  4A3J F;  3H3V F;  1TWA E;  3EQL E;  4A3B F;  5IP7 E;  4BY1 E;  2VUM E;  2NVT E;  3HOU E;  5IP9 F;  3HOV F;  4KMU E;  5C44 F;  4LLG E;  5M5W E;  3GTK E;  5IYB F;  3HOW F;  4A3D E;  4C2M E;  3HOZ E;  4C3J F;  3H0G F;  4A3F E;  2NVY F;  3M3Y E;  4A3L E;  2JA7 E;  1TWA F;  5IP7 F;  4BY1 F;  2VUM F;  2NVT F;  2O5I E;  3M4O E;  1I50 E;  3S2D E;  3GTK F;  5M5W F;  2E2J E;  3HOZ F;  4A3D F;  4QIW K;  4C2M F;  1QKL A;  4BY7 E;  4A3F F;  4XSX E;  3HKZ K;  1TWG E;  3CQZ E;  1IW7 E;  1SMY E;  4LK1 E;  1TWH E;  5IYC E;  4AYB K;  4KN7 E;  4BBR E;  4G7Z E;  2JA7 F;  4C3I E;  3GTM E;  2WAQ H;  2PMZ H;  1I50 F;  3K7A E;  4XLN E;  3M4O F;  3S2D F;  2E2J F;  5M5Y E;  4BY7 F;  5IYD E;  2R7Z E;  2A68 E;  5IYC F;  1TWG F;  3CQZ F;  1TWH F; 
#chains in the Genus database with same CATH homology
 4C3I F;  3GTM F;  4MEX E;  5M5Y F;  4Q4Z E;  5IYD F;  2R7Z F;  3HOU F;  4A3E F;  2JA8 F;  2CW0 E;  4YFK E;  4OIN E;  5M3M F;  5BYH E;  4A3G F;  2A69 E;  3S1Q F;  2BE5 E;  2A6E E;  4GZY E;  3M3Y F;  5E18 E;  3H3V G;  3GTQ F;  4A93 F;  3GTO F;  2E2H F;  3PO2 F;  3FKI F;  1YNJ K;  3S14 F;  3RZD F;  4OIP E;  5D4C E;  3S15 F;  1TWF F;  4C3H F;  4OIO E;  5FJ8 F;  1I3Q F;  3K7A F;  3S1R F;  5C4X F;  2WAQ K;  4XLP E;  2PMZ K;  4A3I F;  4JK1 E;  5TMC E;  3S1N F;  2JA6 F;  1HQM E;  3GTP F;  4LJZ E;  4YG2 E;  4LK0 E;  5E17 E;  3S1M F;  2R93 F;  3DXJ E;  5D4D E;  4BXX F;  3PO3 F;  1TWG F;  3HOY F;  1K83 F;  5FLM F;  5M3F F;  4Q5S E;  5IPL E;  4XSZ E;  4ZH4 E;  1R9T F;  4OIR E;  2B63 F;  4A3M F;  3RZO F;  4Y52 F;  3HOX F;  4A3C F;  2PPB E;  3S2H F;  2WB1 I;  1SFO F;  4KN4 E;  4BBS F;  1WCM F;  4MQ9 E;  4G7H E;  2YU9 F;  3GTL F;  5M5X F;  5C3E F;  2Y0S I;  3S17 F;  3S16 F;  4Y7N F;  2O5J E;  3GTJ F;  4A3K F;  4YFX E;  3WOD E;  2E2I F;  5C4J F;  3GTG F;  1YNN K;  2A6H E;  4MEY E;  1I6H F;  4OIQ E;  1TWC F;  1I6V E;  4YFN E;  2KRX A;  2NVQ F;  2R92 F;  2JA5 F;  5TMF E;  2NVX F;  4G7O E;  3I4M F;  3I4N F;  4X6A F;  1Y1W F;  1ZYR E;  5D4E E;  1Y1V F;  4A3J F;  3EQL E;  4A3B F;  5IP9 F;  3HOV F;  4KMU E;  5C44 F;  4LLG E;  5IYB F;  3HOW F;  4C3J F;  3H0G F;  2NVY F;  1TWA F;  5IP7 F;  4BY1 F;  2VUM F;  2NVT F;  2O5I E;  3GTK F;  5M5W F;  3HOZ F;  4A3D F;  4QIW K;  4C2M F;  1QKL A;  4A3F F;  4XSX E;  3HKZ K;  4LK1 E;  4AYB K;  1IW7 E;  1SMY E;  4G7Z E;  2JA7 F;  4A3L F;  4KN7 E;  3M4O F;  1I50 F;  4XLN E;  3S2D F;  2E2J F;  4BY7 F;  2A68 E;  5IYC F;  4BBR F;  3CQZ F;  1TWH F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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