5M5YE

Rna polymerase i elongation complex 2
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 53
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5m5yE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5m5yE02
2E2IE 3S1ME 1I6HE 2YU9E 4QIWH 3HOXE 4BBRE 3HOWE 3GTGE 2E2JE 3S16E 1I3QE 3HOYE 1Y1WE 3PO2E 5M5WE 3GTQE 3HOZE 4A3FE 4C3JE 1WCME 3S1RE 1DZFA 3GTKE 2R7ZE 3S14E 4A3DE 4A3GE 5IP9E 5C44E 3S2HE 4A3KE 2JA5E 1R9TE 3M4OE 4AYBH 5FJ8E 4A3IE 3S1NE 3HKZH 1I50E 2VUME 4BBSE 3M3YE 4X6AE 5IYCE 3GTPE 3HOVE 1TWAE 5M5XE 5FLME 3S2DE 2JA7E 1Y1VE 4A3BE 5M5YE 2JA6E 4C3IE 4Y52E 4A93E 3FKIE 3CQZE 1TWFE 3RZOE 3K7AE 3S1QE 3H0GE 4BXXE 2WAQH 2NVXE 3S17E 3GTME 3HOUE 3PO3E 4A3JE 2E2HE 4Y7NE 4A3CE 4C2ME 5C4JE 5IYBE 4BY1E 3I4NE 2PMZH 2WB1H 1SFOE 3I4ME 3S15E 5M3FE 5C4XE 3GTOE 1TWHE 1TWGE 2JA8E 2Y0SH 4A3ME 2NVTE 1K83E 5C3EE 3H3VF 3GTJE 2R92E 1TWCE 2R93E 4A3LE 5IP7E 3GTLE 4A3EE 1EIKA 2NVYE 5M3ME 4BY7E 2B63E 3RZDE 4C3HE 5IYDE 2NVQE
chains in the Genus database with same CATH superfamily
2E2IE 3S1ME 4LJZE 2JA6F 4C3IF 4Y52F 1I6HE 4A93F 2YU9E 3FKIF 4Q4ZE 4G7ZE 3CQZF 4QIWH 3HOXE 4BBRE 1TWFF 3HOWE 4XLNE 3GTGE 2E2JE 3RZOF 3S16E 4LLGE 3K7AF 1I3QE 3HOYE 5BYHE 3S1QF 5D4EE 1Y1WE 3PO2E 1SMYE 3H0GF 4BXXF 5M5WE 3GTQE 3HOZE 2NVXF 3S17F 5IPLE 3GTMF 4A3FE 3HOUF 4C3JE 3PO3F 4A3JF 1WCME 3S1RE 2E2HF 1QKLA 2A6EE 4Y7NF 1DZFA 4C2MF 4A3CF 3GTKE 5C4JF 5IYBF 2R7ZE 4BY1F 3I4NF 3S14E 4A3DE 4A3GE 2WAQK 1SFOF 3H3VG 3I4MF 5IP9E 5C44E 2KRXA 4XLPE 3S15F 4OIPE 3S2HE 5M3FF 5C4XF 4A3KE 3GTOF 2E2JF 2JA5E 1R9TE 1TWHF 1TWGF 3M4OE 4AYBH 2WB1I 5FJ8E 2JA8F 4A3MF 4OIOE 1K83F 4A3IE 3S1NE 2NVTF 2PMZK 5C3EF 3GTJF 3HKZH 2R92F 1TWCF 1I50E 4XSXE 2VUME 4YFNE 4KN4E 4BBSE 5TMCE 1ZYRE 3WODE 2R93F 4KMUE 5IP7F 3M3YE 5D4CE 3GTLF 2Y0SI 4A3EF 4A3LF 4X6AE 2NVYF 5M3MF 5IYCE 5TMFE 3GTPE 4BY7F 2B63F 3HOVE 3RZDF 4C3HF 1YNNK 4G7HE 4OIQE 5IYDF 2O5JE 2NVQF 3HOZF 2O5IE 2E2IF 1TWAE 5M5XE 2A68E 3S1MF 5FLME 3S2DE 2JA7E 1Y1VE 4ZH4E 2PPBE 4A3BE 2YU9F 1I6HF 5M5YE 4JK1E 3HOXF 2JA6E 4BBRF 4C3IE 3HOWF 3GTGF 4MEYE 4Y52E 4A93E 3S16F 3FKIE 1I3QF 3HOYF 3CQZE 1TWFE 3RZOE 3DXJE 1Y1WF 3PO2F 5E17E 2A69E 5M5WF 3K7AE 3GTQF 3S1QE 5E18E 4C3JF 4A3FF 3H0GE 4BXXE 1WCMF 2WAQH 4AYBK 5IYCF 2NVXE 3S17E 4QIWK 3S1RF 3GTME 3HOUE 3PO3E 2BE5E 4A3JE 3GTKF 2E2HE 3HKZK 5D4DE 2R7ZF 4GZYE 4Y7NE 4A3CE 4C2ME 3S14F 4A3DF 5C4JE 4A3GF 5IP9F 5M5XF 5IYBE 4BY1E 4LK1E 3I4NE 5C44F 4YFXE 2PMZH 2WB1H 1SFOE 3S2HF 3I4ME 3EQLE 4XSZE 3S15E 4A3KF 4MEXE 2JA5F 1R9TF 3M4OF 5M3FE 5FJ8F 1HQME 5C4XE 4OIRE 3GTOE 4A3BF 4A3IF 3S1NF 1TWHE 2A6HE 1TWGE 1I50F 2JA8E 2Y0SH 4MQ9E 2VUMF 4A3ME 2NVTE 1K83E 4YFKE 4BBSF 5C3EE 3H3VF 3GTJE 2R92E 1I6VE 1TWCE 3M3YF 4LK0E 2CW0E 4X6AF 2R93E 4A3LE 5IP7E 3GTLE 4YG2E 4OINE 4A3EE 3GTPF 1EIKA 3HOVF 2NVYE 4Q5SE 5M3ME 4BY7E 1IW7E 2B63E 4G7OE 3RZDE 1TWAF 4C3HE 4KN7E 5FLMF 5IYDE 1YNJK 1Y1VF 2NVQE 2JA7F 3S2DF 5M5YF
chains in the Genus database with same CATH topology
2E2IE 3S1ME 1I6HE 2YU9E 4QIWH 3HOXE 4BBRE 3HOWE 3GTGE 2E2JE 3S16E 1I3QE 3HOYE 1Y1WE 3PO2E 5M5WE 3GTQE 3HOZE 4A3FE 4C3JE 1WCME 3S1RE 1DZFA 3GTKE 2R7ZE 3S14E 4A3DE 4A3GE 5IP9E 5C44E 3S2HE 4A3KE 2JA5E 1R9TE 3M4OE 4AYBH 5FJ8E 4A3IE 3S1NE 3HKZH 1I50E 2VUME 4BBSE 3M3YE 4X6AE 5IYCE 3GTPE 3HOVE 1TWAE 5M5XE 5FLME 3S2DE 2JA7E 1Y1VE 4A3BE 5M5YE 2JA6E 4C3IE 4Y52E 4A93E 3FKIE 3CQZE 1TWFE 3RZOE 3K7AE 3S1QE 3H0GE 4BXXE 2WAQH 2NVXE 3S17E 3GTME 3HOUE 3PO3E 4A3JE 2E2HE 4Y7NE 4A3CE 4C2ME 5C4JE 5IYBE 4BY1E 3I4NE 2PMZH 2WB1H 1SFOE 3I4ME 3S15E 5M3FE 5C4XE 3GTOE 1TWHE 1TWGE 2JA8E 2Y0SH 4A3ME 2NVTE 1K83E 5C3EE 3H3VF 3GTJE 2R92E 1TWCE 2R93E 4A3LE 5IP7E 3GTLE 4A3EE 1EIKA 2NVYE 5M3ME 4BY7E 2B63E 3RZDE 4C3HE 5IYDE 2NVQE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E2I E;  3S1M E;  1I6H E;  2YU9 E;  4QIW H;  3HOX E;  4BBR E;  3HOW E;  3GTG E;  2E2J E;  3S16 E;  1I3Q E;  3HOY E;  1Y1W E;  3PO2 E;  5M5W E;  3GTQ E;  3HOZ E;  4A3F E;  4C3J E;  1WCM E;  3S1R E;  1DZF A;  3GTK E;  2R7Z E;  3S14 E;  4A3D E;  4A3G E;  5IP9 E;  5C44 E;  3S2H E;  4A3K E;  2JA5 E;  1R9T E;  3M4O E;  4AYB H;  5FJ8 E;  4A3I E;  3S1N E;  3HKZ H;  1I50 E;  2VUM E;  4BBS E;  3M3Y E;  4X6A E;  5IYC E;  3GTP E;  3HOV E;  1TWA E;  5M5X E;  5FLM E;  3S2D E;  2JA7 E;  1Y1V E;  4A3B E;  5M5Y E;  2JA6 E;  4C3I E;  4Y52 E;  4A93 E;  3FKI E;  3CQZ E;  1TWF E;  3RZO E;  3K7A E;  3S1Q E;  3H0G E;  4BXX E;  2WAQ H;  2NVX E;  3S17 E;  3GTM E;  3HOU E;  3PO3 E;  4A3J E;  2E2H E;  4Y7N E;  4A3C E;  4C2M E;  5C4J E;  5IYB E;  4BY1 E;  3I4N E;  2PMZ H;  2WB1 H;  1SFO E;  3I4M E;  3S15 E;  5M3F E;  5C4X E;  3GTO E;  1TWH E;  1TWG E;  2JA8 E;  2Y0S H;  4A3M E;  2NVT E;  1K83 E;  5C3E E;  3H3V F;  3GTJ E;  2R92 E;  1TWC E;  2R93 E;  4A3L E;  5IP7 E;  3GTL E;  4A3E E;  1EIK A;  2NVY E;  5M3M E;  4BY7 E;  2B63 E;  3RZD E;  4C3H E;  5IYD E;  2NVQ E; 
#chains in the Genus database with same CATH topology
 2E2I E;  3S1M E;  4LJZ E;  2JA6 F;  4C3I F;  4Y52 F;  1I6H E;  4A93 F;  2YU9 E;  3FKI F;  4Q4Z E;  4G7Z E;  3CQZ F;  4QIW H;  3HOX E;  4BBR E;  1TWF F;  3HOW E;  4XLN E;  3GTG E;  2E2J E;  3RZO F;  3S16 E;  4LLG E;  3K7A F;  1I3Q E;  3HOY E;  5BYH E;  3S1Q F;  5D4E E;  1Y1W E;  3PO2 E;  1SMY E;  3H0G F;  4BXX F;  5M5W E;  3GTQ E;  3HOZ E;  2NVX F;  3S17 F;  5IPL E;  3GTM F;  4A3F E;  3HOU F;  4C3J E;  3PO3 F;  4A3J F;  1WCM E;  3S1R E;  2E2H F;  1QKL A;  2A6E E;  4Y7N F;  1DZF A;  4C2M F;  4A3C F;  3GTK E;  5C4J F;  5IYB F;  2R7Z E;  4BY1 F;  3I4N F;  3S14 E;  4A3D E;  4A3G E;  2WAQ K;  1SFO F;  3H3V G;  3I4M F;  5IP9 E;  5C44 E;  2KRX A;  4XLP E;  3S15 F;  4OIP E;  3S2H E;  5M3F F;  5C4X F;  4A3K E;  3GTO F;  2E2J F;  2JA5 E;  1R9T E;  1TWH F;  1TWG F;  3M4O E;  4AYB H;  2WB1 I;  5FJ8 E;  2JA8 F;  4A3M F;  4OIO E;  1K83 F;  4A3I E;  3S1N E;  2NVT F;  2PMZ K;  5C3E F;  3GTJ F;  3HKZ H;  2R92 F;  1TWC F;  1I50 E;  4XSX E;  2VUM E;  4YFN E;  4KN4 E;  4BBS E;  5TMC E;  1ZYR E;  3WOD E;  2R93 F;  4KMU E;  5IP7 F;  3M3Y E;  5D4C E;  3GTL F;  2Y0S I;  4A3E F;  4A3L F;  4X6A E;  2NVY F;  5M3M F;  5IYC E;  5TMF E;  3GTP E;  4BY7 F;  2B63 F;  3HOV E;  3RZD F;  4C3H F;  1YNN K;  4G7H E;  4OIQ E;  5IYD F;  2O5J E;  2NVQ F;  3HOZ F;  2O5I E;  2E2I F;  1TWA E;  5M5X E;  2A68 E;  3S1M F;  5FLM E;  3S2D E;  2JA7 E;  1Y1V E;  4ZH4 E;  2PPB E;  4A3B E;  2YU9 F;  1I6H F;  5M5Y E;  4JK1 E;  3HOX F;  2JA6 E;  4BBR F;  4C3I E;  3HOW F;  3GTG F;  4MEY E;  4Y52 E;  4A93 E;  3S16 F;  3FKI E;  1I3Q F;  3HOY F;  3CQZ E;  1TWF E;  3RZO E;  3DXJ E;  1Y1W F;  3PO2 F;  5E17 E;  2A69 E;  5M5W F;  3K7A E;  3GTQ F;  3S1Q E;  5E18 E;  4C3J F;  4A3F F;  3H0G E;  4BXX E;  1WCM F;  2WAQ H;  4AYB K;  5IYC F;  2NVX E;  3S17 E;  4QIW K;  3S1R F;  3GTM E;  3HOU E;  3PO3 E;  2BE5 E;  4A3J E;  3GTK F;  2E2H E;  3HKZ K;  5D4D E;  2R7Z F;  4GZY E;  4Y7N E;  4A3C E;  4C2M E;  3S14 F;  4A3D F;  5C4J E;  4A3G F;  5IP9 F;  5M5X F;  5IYB E;  4BY1 E;  4LK1 E;  3I4N E;  5C44 F;  4YFX E;  2PMZ H;  2WB1 H;  1SFO E;  3S2H F;  3I4M E;  3EQL E;  4XSZ E;  3S15 E;  4A3K F;  4MEX E;  2JA5 F;  1R9T F;  3M4O F;  5M3F E;  5FJ8 F;  1HQM E;  5C4X E;  4OIR E;  3GTO E;  4A3B F;  4A3I F;  3S1N F;  1TWH E;  2A6H E;  1TWG E;  1I50 F;  2JA8 E;  2Y0S H;  4MQ9 E;  2VUM F;  4A3M E;  2NVT E;  1K83 E;  4YFK E;  4BBS F;  5C3E E;  3H3V F;  3GTJ E;  2R92 E;  1I6V E;  1TWC E;  3M3Y F;  4LK0 E;  2CW0 E;  4X6A F;  2R93 E;  4A3L E;  5IP7 E;  3GTL E;  4YG2 E;  4OIN E;  4A3E E;  3GTP F;  1EIK A;  3HOV F;  2NVY E;  4Q5S E;  5M3M E;  4BY7 E;  1IW7 E;  2B63 E;  4G7O E;  3RZD E;  1TWA F;  4C3H E;  4KN7 E;  5FLM F;  5IYD E;  1YNJ K;  1Y1V F;  2NVQ E;  2JA7 F;  3S2D F;  5M5Y F; 
#chains in the Genus database with same CATH homology
 2E2I E;  3S1M E;  1I6H E;  2YU9 E;  4QIW H;  3HOX E;  4BBR E;  3HOW E;  3GTG E;  2E2J E;  3S16 E;  1I3Q E;  3HOY E;  1Y1W E;  3PO2 E;  5M5W E;  3GTQ E;  3HOZ E;  4A3F E;  4C3J E;  1WCM E;  3S1R E;  1DZF A;  3GTK E;  2R7Z E;  3S14 E;  4A3D E;  4A3G E;  5IP9 E;  5C44 E;  3S2H E;  4A3K E;  2JA5 E;  1R9T E;  3M4O E;  4AYB H;  5FJ8 E;  4A3I E;  3S1N E;  3HKZ H;  1I50 E;  2VUM E;  4BBS E;  3M3Y E;  4X6A E;  5IYC E;  3GTP E;  3HOV E;  1TWA E;  5M5X E;  5FLM E;  3S2D E;  2JA7 E;  1Y1V E;  4A3B E;  5M5Y E;  2JA6 E;  4C3I E;  4Y52 E;  4A93 E;  3FKI E;  3CQZ E;  1TWF E;  3RZO E;  3K7A E;  3S1Q E;  3H0G E;  4BXX E;  2WAQ H;  2NVX E;  3S17 E;  3GTM E;  3HOU E;  3PO3 E;  4A3J E;  2E2H E;  4Y7N E;  4A3C E;  4C2M E;  5C4J E;  5IYB E;  4BY1 E;  3I4N E;  2PMZ H;  2WB1 H;  1SFO E;  3I4M E;  3S15 E;  5M3F E;  5C4X E;  3GTO E;  1TWH E;  1TWG E;  2JA8 E;  2Y0S H;  4A3M E;  2NVT E;  1K83 E;  5C3E E;  3H3V F;  3GTJ E;  2R92 E;  1TWC E;  2R93 E;  4A3L E;  5IP7 E;  3GTL E;  4A3E E;  1EIK A;  2NVY E;  5M3M E;  4BY7 E;  2B63 E;  3RZD E;  4C3H E;  5IYD E;  2NVQ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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