1O0XA

Crystal structure of methionine aminopeptidase (tm1478) from thermotoga maritima at 1.90 a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
249
structure length
249
Chain Sequence
MIRIKTPSEIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGYKYATCVSVNEEVVHGLPLKEKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGRELHEDPQIPNYGTPGTGVVLRKGMTLAIEPMVSEGDWRVVVKEDGWTAVTVDGSRCAHFEHTILITENGAEILTKE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
pubmed doi rcsb
source organism Thermotoga maritima
total genus 84
structure length 249
sequence length 249
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1o0xA00
4S00A 2GU4A 2EVOA 1O0XA 5CNXA 2Q96A 1WN1A 2BN7A 3IG4A 2OKNA 2P98A 5E5BA 2P9AA 1C24A 1PV9A 1B6AA 1QZYA 4FLIA 4U76A 2BWYA 1C21A 4FLKA 5CLSA 4U70A 1WY2A 2Q95A 2EA2A 1XGSA 2GG2A 3MX6A 2B3HA 3L24A 3RVAA 3BIPA 2GG5A 2GA2A 2GU5A 4JUQA 4MATA 4ZWPA 1YVMA 2GGCA 1KQ0A 4PNCA 2BHDA 2GU7A 1C27A 4U71A 5CDEA 5FCHA 1XNZA 3RORA 1XGOA 4U69A 4IDYA 2EVMA 2NQ6A 5JHUA 4IKTA 1QXYA 4IKSA 5D6FA 1M35A 4FO8A 2GU6A 3BIQA 1YJ3A 5CDLA 3CB6A 4ZWUA 5CDVA 3S6BA 1A16A 4Z7MA 3TB5A 4FO7A 2V3YA 5JI6A 4U75A 4S2TP 2BH3A 4IU6A 1XGMA 5D6EA 5JFRA 3MR1A 2V6CA 1B59A 1JAWA 2GG3A 2Q93A 3D27A 4U73A 1QXZA 3L7GA 4FUKA 2GZ5A 2GG9A 3PKBA 2Q92A 4QR8A 1YW8A 4U6JA 4IF7A 2B3LA 4KM3A 1BN5A 3IU7A 4S01A 4U1BA 2GGBA 4RZZA 4RZYA 2BWTA 4RGZ1 3TAVA 3FMRA 1WLRA 2EVCA 3PKCA 3Q6DA 1CHMA 4EGEA 2ADUA 5FCFA 4U6EA 1Y1NA 2P99A 2BHAA 2GTXA 2BWUA 3MATA 2DFIA 4B28A 2IW2A 4S2RP 1YW9A 3FMQA 2GG0A 3IU8A 2GG8A 4FLJA 1C23A 2HOWA 1KP0A 1R5HA 1KQ9A 4IECA 5CIKA 3PKEA 4HXXA 4A6VA 4IPAA 1WKMA 4IKRA 2Q94A 2V3XA 1MATA 1R58A 2BB7A 3CB5A 1XGNA 1YW7A 3FM3A 2BWSA 4IKUA 3BITA 2OAZA 4U6WA 1WL9A 1WBQA 3PKDA 3PKAA 4FKCA 4PV4A 2BWXA 1R5GA 2BWVA 4U6CA 2BHCA 4R60A 2V3ZA 4A6WA 2BWWA 3IU9A 1W7VA 1N51A 2NQ7A 2BHBA 2EA4A 2GG7A 2ZSGA 1C22A 1WL6A 2MATA 4FLLA 1BOAA 2Q8KA 2B3KA 4ZWOA 5CE6A 4OOKA 1QXWA 4U6ZA 4ZNGA 1W2MA 2G6PA 3CTZA
chains in the Genus database with same CATH superfamily
4S00A 2GU4A 2EVOA 1O0XA 5CNXA 2Q96A 1WN1A 2BN7A 3IG4A 2OKNA 2P98A 5E5BA 2P9AA 1C24A 1PV9A 1B6AA 1QZYA 4FLIA 4U76A 2BWYA 1C21A 4FLKA 5CLSA 4U70A 1WY2A 2Q95A 2EA2A 1XGSA 2GG2A 3MX6A 2B3HA 3L24A 3RVAA 3BIPA 2GG5A 2GA2A 2GU5A 4JUQA 4MATA 4ZWPA 1YVMA 2GGCA 1KQ0A 4PNCA 2BHDA 2GU7A 1C27A 4U71A 5CDEA 5FCHA 1XNZA 3RORA 1XGOA 4U69A 4IDYA 2EVMA 2NQ6A 5JHUA 4IKTA 1QXYA 4IKSA 5D6FA 1M35A 4FO8A 2GU6A 3BIQA 1YJ3A 5CDLA 3CB6A 4ZWUA 5CDVA 3S6BA 1A16A 4Z7MA 3TB5A 4FO7A 2V3YA 5JI6A 4U75A 4S2TP 2BH3A 4IU6A 1XGMA 5D6EA 5JFRA 3MR1A 2V6CA 1B59A 1JAWA 2GG3A 2Q93A 3D27A 4U73A 1QXZA 3L7GA 4FUKA 2GZ5A 2GG9A 3PKBA 2Q92A 4QR8A 1YW8A 4U6JA 4IF7A 2B3LA 4KM3A 1BN5A 3IU7A 4S01A 4U1BA 2GGBA 4RZZA 4RZYA 2BWTA 4RGZ1 3TAVA 3FMRA 1WLRA 2EVCA 3PKCA 3Q6DA 1CHMA 4EGEA 2ADUA 5FCFA 4U6EA 1Y1NA 2P99A 2BHAA 2GTXA 2BWUA 3MATA 2DFIA 4B28A 2IW2A 4S2RP 1YW9A 3FMQA 2GG0A 3IU8A 2GG8A 4FLJA 1C23A 2HOWA 1KP0A 1R5HA 1KQ9A 4IECA 5CIKA 3PKEA 4HXXA 4A6VA 4IPAA 1WKMA 4IKRA 2Q94A 2V3XA 1MATA 1R58A 2BB7A 3CB5A 1XGNA 1YW7A 3FM3A 2BWSA 4IKUA 3BITA 2OAZA 4U6WA 1WL9A 1WBQA 3PKDA 3PKAA 4FKCA 4PV4A 2BWXA 1R5GA 2BWVA 4U6CA 2BHCA 4R60A 2V3ZA 4A6WA 2BWWA 3IU9A 1W7VA 1N51A 2NQ7A 2BHBA 2EA4A 2GG7A 2ZSGA 1C22A 1WL6A 2MATA 4FLLA 1BOAA 2Q8KA 2B3KA 4ZWOA 5CE6A 4OOKA 1QXWA 4U6ZA 4ZNGA 1W2MA 2G6PA 3CTZA
chains in the Genus database with same CATH topology
4S00A 2GU4A 2EVOA 1O0XA 5CNXA 2Q96A 1WN1A 2BN7A 3IG4A 2OKNA 2P98A 5E5BA 2P9AA 1C24A 1PV9A 1B6AA 1QZYA 4FLIA 4U76A 2BWYA 1C21A 4FLKA 5CLSA 4U70A 1WY2A 2Q95A 2EA2A 1XGSA 2GG2A 3MX6A 2B3HA 3L24A 3RVAA 3BIPA 2GG5A 2GA2A 2GU5A 4JUQA 4MATA 4ZWPA 1YVMA 2GGCA 1KQ0A 4PNCA 2BHDA 2GU7A 1C27A 4U71A 5CDEA 5FCHA 1XNZA 3RORA 1XGOA 4U69A 4IDYA 2EVMA 2NQ6A 5JHUA 4IKTA 1QXYA 4IKSA 5D6FA 1M35A 4FO8A 2GU6A 3BIQA 1YJ3A 5CDLA 3CB6A 4ZWUA 5CDVA 3S6BA 1A16A 4Z7MA 3TB5A 4FO7A 2V3YA 5JI6A 4U75A 4S2TP 2BH3A 4IU6A 1XGMA 5D6EA 5JFRA 3MR1A 2V6CA 1B59A 1JAWA 2GG3A 2Q93A 3D27A 4U73A 1QXZA 3L7GA 4FUKA 2GZ5A 2GG9A 3PKBA 2Q92A 4QR8A 1YW8A 4U6JA 4IF7A 2B3LA 4KM3A 1BN5A 3IU7A 4S01A 4U1BA 2GGBA 4RZZA 4RZYA 2BWTA 4RGZ1 3TAVA 3FMRA 1WLRA 2EVCA 3PKCA 3Q6DA 1CHMA 4EGEA 2ADUA 5FCFA 4U6EA 1Y1NA 2P99A 2BHAA 2GTXA 2BWUA 3MATA 2DFIA 4B28A 2IW2A 4S2RP 1YW9A 3FMQA 2GG0A 3IU8A 2GG8A 4FLJA 1C23A 2HOWA 1KP0A 1R5HA 1KQ9A 4IECA 5CIKA 3PKEA 4HXXA 4A6VA 4IPAA 1WKMA 4IKRA 2Q94A 2V3XA 1MATA 1R58A 2BB7A 3CB5A 1XGNA 1YW7A 3FM3A 2BWSA 4IKUA 3BITA 2OAZA 4U6WA 1WL9A 1WBQA 3PKDA 3PKAA 4FKCA 4PV4A 2BWXA 1R5GA 2BWVA 4U6CA 2BHCA 4R60A 2V3ZA 4A6WA 2BWWA 3IU9A 1W7VA 1N51A 2NQ7A 2BHBA 2EA4A 2GG7A 2ZSGA 1C22A 1WL6A 2MATA 4FLLA 1BOAA 2Q8KA 2B3KA 4ZWOA 5CE6A 4OOKA 1QXWA 4U6ZA 4ZNGA 1W2MA 2G6PA 3CTZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4S00 A;  2GU4 A;  2EVO A;  1O0X A;  5CNX A;  2Q96 A;  1WN1 A;  2BN7 A;  3IG4 A;  2OKN A;  2P98 A;  5E5B A;  2P9A A;  1C24 A;  1PV9 A;  1B6A A;  1QZY A;  4FLI A;  4U76 A;  2BWY A;  1C21 A;  4FLK A;  5CLS A;  4U70 A;  1WY2 A;  2Q95 A;  2EA2 A;  1XGS A;  2GG2 A;  3MX6 A;  2B3H A;  3L24 A;  3RVA A;  3BIP A;  2GG5 A;  2GA2 A;  2GU5 A;  4JUQ A;  4MAT A;  4ZWP A;  1YVM A;  2GGC A;  1KQ0 A;  4PNC A;  2BHD A;  2GU7 A;  1C27 A;  4U71 A;  5CDE A;  5FCH A;  1XNZ A;  3ROR A;  1XGO A;  4U69 A;  4IDY A;  2EVM A;  2NQ6 A;  5JHU A;  4IKT A;  1QXY A;  4IKS A;  5D6F A;  1M35 A;  4FO8 A;  2GU6 A;  3BIQ A;  1YJ3 A;  5CDL A;  3CB6 A;  4ZWU A;  5CDV A;  3S6B A;  1A16 A;  4Z7M A;  3TB5 A;  4FO7 A;  2V3Y A;  5JI6 A;  4U75 A;  4S2T P;  2BH3 A;  4IU6 A;  1XGM A;  5D6E A;  5JFR A;  3MR1 A;  2V6C A;  1B59 A;  1JAW A;  2GG3 A;  2Q93 A;  3D27 A;  4U73 A;  1QXZ A;  3L7G A;  4FUK A;  2GZ5 A;  2GG9 A;  3PKB A;  2Q92 A;  4QR8 A;  1YW8 A;  4U6J A;  4IF7 A;  2B3L A;  4KM3 A;  1BN5 A;  3IU7 A;  4S01 A;  4U1B A;  2GGB A;  4RZZ A;  4RZY A;  2BWT A;  4RGZ 1;  3TAV A;  3FMR A;  1WLR A;  2EVC A;  3PKC A;  3Q6D A;  1CHM A;  4EGE A;  2ADU A;  5FCF A;  4U6E A;  1Y1N A;  2P99 A;  2BHA A;  2GTX A;  2BWU A;  3MAT A;  2DFI A;  4B28 A;  2IW2 A;  4S2R P;  1YW9 A;  3FMQ A;  2GG0 A;  3IU8 A;  2GG8 A;  4FLJ A;  1C23 A;  2HOW A;  1KP0 A;  1R5H A;  1KQ9 A;  4IEC A;  5CIK A;  3PKE A;  4HXX A;  4A6V A;  4IPA A;  1WKM A;  4IKR A;  2Q94 A;  2V3X A;  1MAT A;  1R58 A;  2BB7 A;  3CB5 A;  1XGN A;  1YW7 A;  3FM3 A;  2BWS A;  4IKU A;  3BIT A;  2OAZ A;  4U6W A;  1WL9 A;  1WBQ A;  3PKD A;  3PKA A;  4FKC A;  4PV4 A;  2BWX A;  1R5G A;  2BWV A;  4U6C A;  2BHC A;  4R60 A;  2V3Z A;  4A6W A;  2BWW A;  3IU9 A;  1W7V A;  1N51 A;  2NQ7 A;  2BHB A;  2EA4 A;  2GG7 A;  2ZSG A;  1C22 A;  1WL6 A;  2MAT A;  4FLL A;  1BOA A;  2Q8K A;  2B3K A;  4ZWO A;  5CE6 A;  4OOK A;  1QXW A;  4U6Z A;  4ZNG A;  1W2M A;  2G6P A;  3CTZ A; 
#chains in the Genus database with same CATH topology
 4S00 A;  2GU4 A;  2EVO A;  1O0X A;  5CNX A;  2Q96 A;  1WN1 A;  2BN7 A;  3IG4 A;  2OKN A;  2P98 A;  5E5B A;  2P9A A;  1C24 A;  1PV9 A;  1B6A A;  1QZY A;  4FLI A;  4U76 A;  2BWY A;  1C21 A;  4FLK A;  5CLS A;  4U70 A;  1WY2 A;  2Q95 A;  2EA2 A;  1XGS A;  2GG2 A;  3MX6 A;  2B3H A;  3L24 A;  3RVA A;  3BIP A;  2GG5 A;  2GA2 A;  2GU5 A;  4JUQ A;  4MAT A;  4ZWP A;  1YVM A;  2GGC A;  1KQ0 A;  4PNC A;  2BHD A;  2GU7 A;  1C27 A;  4U71 A;  5CDE A;  5FCH A;  1XNZ A;  3ROR A;  1XGO A;  4U69 A;  4IDY A;  2EVM A;  2NQ6 A;  5JHU A;  4IKT A;  1QXY A;  4IKS A;  5D6F A;  1M35 A;  4FO8 A;  2GU6 A;  3BIQ A;  1YJ3 A;  5CDL A;  3CB6 A;  4ZWU A;  5CDV A;  3S6B A;  1A16 A;  4Z7M A;  3TB5 A;  4FO7 A;  2V3Y A;  5JI6 A;  4U75 A;  4S2T P;  2BH3 A;  4IU6 A;  1XGM A;  5D6E A;  5JFR A;  3MR1 A;  2V6C A;  1B59 A;  1JAW A;  2GG3 A;  2Q93 A;  3D27 A;  4U73 A;  1QXZ A;  3L7G A;  4FUK A;  2GZ5 A;  2GG9 A;  3PKB A;  2Q92 A;  4QR8 A;  1YW8 A;  4U6J A;  4IF7 A;  2B3L A;  4KM3 A;  1BN5 A;  3IU7 A;  4S01 A;  4U1B A;  2GGB A;  4RZZ A;  4RZY A;  2BWT A;  4RGZ 1;  3TAV A;  3FMR A;  1WLR A;  2EVC A;  3PKC A;  3Q6D A;  1CHM A;  4EGE A;  2ADU A;  5FCF A;  4U6E A;  1Y1N A;  2P99 A;  2BHA A;  2GTX A;  2BWU A;  3MAT A;  2DFI A;  4B28 A;  2IW2 A;  4S2R P;  1YW9 A;  3FMQ A;  2GG0 A;  3IU8 A;  2GG8 A;  4FLJ A;  1C23 A;  2HOW A;  1KP0 A;  1R5H A;  1KQ9 A;  4IEC A;  5CIK A;  3PKE A;  4HXX A;  4A6V A;  4IPA A;  1WKM A;  4IKR A;  2Q94 A;  2V3X A;  1MAT A;  1R58 A;  2BB7 A;  3CB5 A;  1XGN A;  1YW7 A;  3FM3 A;  2BWS A;  4IKU A;  3BIT A;  2OAZ A;  4U6W A;  1WL9 A;  1WBQ A;  3PKD A;  3PKA A;  4FKC A;  4PV4 A;  2BWX A;  1R5G A;  2BWV A;  4U6C A;  2BHC A;  4R60 A;  2V3Z A;  4A6W A;  2BWW A;  3IU9 A;  1W7V A;  1N51 A;  2NQ7 A;  2BHB A;  2EA4 A;  2GG7 A;  2ZSG A;  1C22 A;  1WL6 A;  2MAT A;  4FLL A;  1BOA A;  2Q8K A;  2B3K A;  4ZWO A;  5CE6 A;  4OOK A;  1QXW A;  4U6Z A;  4ZNG A;  1W2M A;  2G6P A;  3CTZ A; 
#chains in the Genus database with same CATH homology
 4S00 A;  2GU4 A;  2EVO A;  1O0X A;  5CNX A;  2Q96 A;  1WN1 A;  2BN7 A;  3IG4 A;  2OKN A;  2P98 A;  5E5B A;  2P9A A;  1C24 A;  1PV9 A;  1B6A A;  1QZY A;  4FLI A;  4U76 A;  2BWY A;  1C21 A;  4FLK A;  5CLS A;  4U70 A;  1WY2 A;  2Q95 A;  2EA2 A;  1XGS A;  2GG2 A;  3MX6 A;  2B3H A;  3L24 A;  3RVA A;  3BIP A;  2GG5 A;  2GA2 A;  2GU5 A;  4JUQ A;  4MAT A;  4ZWP A;  1YVM A;  2GGC A;  1KQ0 A;  4PNC A;  2BHD A;  2GU7 A;  1C27 A;  4U71 A;  5CDE A;  5FCH A;  1XNZ A;  3ROR A;  1XGO A;  4U69 A;  4IDY A;  2EVM A;  2NQ6 A;  5JHU A;  4IKT A;  1QXY A;  4IKS A;  5D6F A;  1M35 A;  4FO8 A;  2GU6 A;  3BIQ A;  1YJ3 A;  5CDL A;  3CB6 A;  4ZWU A;  5CDV A;  3S6B A;  1A16 A;  4Z7M A;  3TB5 A;  4FO7 A;  2V3Y A;  5JI6 A;  4U75 A;  4S2T P;  2BH3 A;  4IU6 A;  1XGM A;  5D6E A;  5JFR A;  3MR1 A;  2V6C A;  1B59 A;  1JAW A;  2GG3 A;  2Q93 A;  3D27 A;  4U73 A;  1QXZ A;  3L7G A;  4FUK A;  2GZ5 A;  2GG9 A;  3PKB A;  2Q92 A;  4QR8 A;  1YW8 A;  4U6J A;  4IF7 A;  2B3L A;  4KM3 A;  1BN5 A;  3IU7 A;  4S01 A;  4U1B A;  2GGB A;  4RZZ A;  4RZY A;  2BWT A;  4RGZ 1;  3TAV A;  3FMR A;  1WLR A;  2EVC A;  3PKC A;  3Q6D A;  1CHM A;  4EGE A;  2ADU A;  5FCF A;  4U6E A;  1Y1N A;  2P99 A;  2BHA A;  2GTX A;  2BWU A;  3MAT A;  2DFI A;  4B28 A;  2IW2 A;  4S2R P;  1YW9 A;  3FMQ A;  2GG0 A;  3IU8 A;  2GG8 A;  4FLJ A;  1C23 A;  2HOW A;  1KP0 A;  1R5H A;  1KQ9 A;  4IEC A;  5CIK A;  3PKE A;  4HXX A;  4A6V A;  4IPA A;  1WKM A;  4IKR A;  2Q94 A;  2V3X A;  1MAT A;  1R58 A;  2BB7 A;  3CB5 A;  1XGN A;  1YW7 A;  3FM3 A;  2BWS A;  4IKU A;  3BIT A;  2OAZ A;  4U6W A;  1WL9 A;  1WBQ A;  3PKD A;  3PKA A;  4FKC A;  4PV4 A;  2BWX A;  1R5G A;  2BWV A;  4U6C A;  2BHC A;  4R60 A;  2V3Z A;  4A6W A;  2BWW A;  3IU9 A;  1W7V A;  1N51 A;  2NQ7 A;  2BHB A;  2EA4 A;  2GG7 A;  2ZSG A;  1C22 A;  1WL6 A;  2MAT A;  4FLL A;  1BOA A;  2Q8K A;  2B3K A;  4ZWO A;  5CE6 A;  4OOK A;  1QXW A;  4U6Z A;  4ZNG A;  1W2M A;  2G6P A;  3CTZ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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