3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
3PKBA 1MATA 2GU5A 5CIKA 5FCFA 3IG4A 1XNZA 2GG9A 3PKEA 1YW9A 1Y1NA 1XGSA 3BIQA 3FMRA 2EVCA 3RVAA 1C21A 2P9AA 4FLIA 4S2TP 4IPAA 4U73A 1B59A 4RZZA 2GU6A 3S6BA 4FO7A 4JUQA 2Q92A 5JFRA 1A16A 1WL6A 2BN7A 3BITA 2GZ5A 2HOWA 3PKAA 4B28A 4FUKA 1W2MA 1JAWA 2BWSA 2DFIA 1BN5A 4U76A 3MATA 4IECA 1XGMA 1C23A 2G6PA 4U71A 2OKNA 1C22A 2BWUA 1C27A 2GG8A 3BIPA 2IW2A 2EVMA 2V6CA 4U6ZA 4IKSA 3D27A 4OOKA 2GTXA 2BHCA 4A6VA 1WBQA 1XGOA 5CDLA 2P98A 4ZWUA 4MATA 2BWTA 3CB6A 5CNXA 3PKDA 4U75A 2BWYA 4S00A 1XGNA 1R5HA 4IDYA 3IU8A 4FO8A 1PV9A 3MX6A 3FMQA 2Q96A 5D6EA 1KQ0A 4PV4A 2OAZA 5D6FA 1KP0A 2Q95A 2GG3A 2GGBA 4U6WA 2BHAA 4S01A 2Q8KA 2B3LA 4IU6A 4U6EA 1QXZA 2GU7A 4Z7MA 1B6AA 4ZWOA 4EGEA 5FCHA 3FM3A 1WL9A 2BH3A 3IU9A 4ZWPA 2GG5A 2EA2A 1WLRA 4PNCA 5CE6A 2GG0A 1YW8A 2ADUA 4R60A 3PKCA 4RZYA 3RORA 4RGZ1 3Q6DA 4FLKA 2B3KA 3L24A 1BOAA 1C24A 1CHMA 2BHBA 1O0XA 2V3XA 1QXWA 3IU7A 4FLLA 1WY2A 1R5GA 1YW7A 2B3HA 4U69A 5JHUA 2GG7A 2BWVA 1N51A 2BWWA 1KQ9A 4IKTA 4QR8A 5CDEA 2NQ7A 3CB5A 5E5BA 2MATA 2EVOA 2V3YA 2GG2A 4U6CA 2BB7A 3L7GA 1YJ3A 2NQ6A 3CTZA 1WKMA 4IKUA 4KM3A 4ZNGA 2BWXA 3TB5A 2BHDA 4FKCA 4A6WA 4IF7A 1R58A 4U1BA 5CDVA 2P99A 4FLJA 1QXYA 2GU4A 2Q94A 2ZSGA 1YVMA 2GA2A 4U6JA 2V3ZA 4U70A 3MR1A 2GGCA 1QZYA 2Q93A 3TAVA 1WN1A 4HXXA 2EA4A 4IKRA 4S2RP 5CLSA 5JI6A 1W7VA 1M35A
chains in the Genus database with same CATH superfamily
3PKBA 1MATA 2GU5A 5CIKA 5FCFA 3IG4A 1XNZA 2GG9A 3PKEA 1YW9A 1Y1NA 1XGSA 3BIQA 3FMRA 2EVCA 3RVAA 1C21A 2P9AA 4FLIA 4S2TP 4IPAA 4U73A 1B59A 4RZZA 2GU6A 3S6BA 4FO7A 4JUQA 2Q92A 5JFRA 1A16A 1WL6A 2BN7A 3BITA 2GZ5A 2HOWA 3PKAA 4B28A 4FUKA 1W2MA 1JAWA 2BWSA 2DFIA 1BN5A 4U76A 3MATA 4IECA 1XGMA 1C23A 2G6PA 4U71A 2OKNA 1C22A 2BWUA 1C27A 2GG8A 3BIPA 2IW2A 2EVMA 2V6CA 4U6ZA 4IKSA 3D27A 4OOKA 2GTXA 2BHCA 4A6VA 1WBQA 1XGOA 5CDLA 2P98A 4ZWUA 4MATA 2BWTA 3CB6A 5CNXA 3PKDA 4U75A 2BWYA 4S00A 1XGNA 1R5HA 4IDYA 3IU8A 4FO8A 1PV9A 3MX6A 3FMQA 2Q96A 5D6EA 1KQ0A 4PV4A 2OAZA 5D6FA 1KP0A 2Q95A 2GG3A 2GGBA 4U6WA 2BHAA 4S01A 2Q8KA 2B3LA 4IU6A 4U6EA 1QXZA 2GU7A 4Z7MA 1B6AA 4ZWOA 4EGEA 5FCHA 3FM3A 1WL9A 2BH3A 3IU9A 4ZWPA 2GG5A 2EA2A 1WLRA 4PNCA 5CE6A 2GG0A 1YW8A 2ADUA 4R60A 3PKCA 4RZYA 3RORA 4RGZ1 3Q6DA 4FLKA 2B3KA 3L24A 1BOAA 1C24A 1CHMA 2BHBA 1O0XA 2V3XA 1QXWA 3IU7A 4FLLA 1WY2A 1R5GA 1YW7A 2B3HA 4U69A 5JHUA 2GG7A 2BWVA 1N51A 2BWWA 1KQ9A 4IKTA 4QR8A 5CDEA 2NQ7A 3CB5A 5E5BA 2MATA 2EVOA 2V3YA 2GG2A 4U6CA 2BB7A 3L7GA 1YJ3A 2NQ6A 3CTZA 1WKMA 4IKUA 4KM3A 4ZNGA 2BWXA 3TB5A 2BHDA 4FKCA 4A6WA 4IF7A 1R58A 4U1BA 5CDVA 2P99A 4FLJA 1QXYA 2GU4A 2Q94A 2ZSGA 1YVMA 2GA2A 4U6JA 2V3ZA 4U70A 3MR1A 2GGCA 1QZYA 2Q93A 3TAVA 1WN1A 4HXXA 2EA4A 4IKRA 4S2RP 5CLSA 5JI6A 1W7VA 1M35A
chains in the Genus database with same CATH topology
3PKBA 1MATA 2GU5A 5CIKA 5FCFA 3IG4A 1XNZA 2GG9A 3PKEA 1YW9A 1Y1NA 1XGSA 3BIQA 3FMRA 2EVCA 3RVAA 1C21A 2P9AA 4FLIA 4S2TP 4IPAA 4U73A 1B59A 4RZZA 2GU6A 3S6BA 4FO7A 4JUQA 2Q92A 5JFRA 1A16A 1WL6A 2BN7A 3BITA 2GZ5A 2HOWA 3PKAA 4B28A 4FUKA 1W2MA 1JAWA 2BWSA 2DFIA 1BN5A 4U76A 3MATA 4IECA 1XGMA 1C23A 2G6PA 4U71A 2OKNA 1C22A 2BWUA 1C27A 2GG8A 3BIPA 2IW2A 2EVMA 2V6CA 4U6ZA 4IKSA 3D27A 4OOKA 2GTXA 2BHCA 4A6VA 1WBQA 1XGOA 5CDLA 2P98A 4ZWUA 4MATA 2BWTA 3CB6A 5CNXA 3PKDA 4U75A 2BWYA 4S00A 1XGNA 1R5HA 4IDYA 3IU8A 4FO8A 1PV9A 3MX6A 3FMQA 2Q96A 5D6EA 1KQ0A 4PV4A 2OAZA 5D6FA 1KP0A 2Q95A 2GG3A 2GGBA 4U6WA 2BHAA 4S01A 2Q8KA 2B3LA 4IU6A 4U6EA 1QXZA 2GU7A 4Z7MA 1B6AA 4ZWOA 4EGEA 5FCHA 3FM3A 1WL9A 2BH3A 3IU9A 4ZWPA 2GG5A 2EA2A 1WLRA 4PNCA 5CE6A 2GG0A 1YW8A 2ADUA 4R60A 3PKCA 4RZYA 3RORA 4RGZ1 3Q6DA 4FLKA 2B3KA 3L24A 1BOAA 1C24A 1CHMA 2BHBA 1O0XA 2V3XA 1QXWA 3IU7A 4FLLA 1WY2A 1R5GA 1YW7A 2B3HA 4U69A 5JHUA 2GG7A 2BWVA 1N51A 2BWWA 1KQ9A 4IKTA 4QR8A 5CDEA 2NQ7A 3CB5A 5E5BA 2MATA 2EVOA 2V3YA 2GG2A 4U6CA 2BB7A 3L7GA 1YJ3A 2NQ6A 3CTZA 1WKMA 4IKUA 4KM3A 4ZNGA 2BWXA 3TB5A 2BHDA 4FKCA 4A6WA 4IF7A 1R58A 4U1BA 5CDVA 2P99A 4FLJA 1QXYA 2GU4A 2Q94A 2ZSGA 1YVMA 2GA2A 4U6JA 2V3ZA 4U70A 3MR1A 2GGCA 1QZYA 2Q93A 3TAVA 1WN1A 4HXXA 2EA4A 4IKRA 4S2RP 5CLSA 5JI6A 1W7VA 1M35A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3PKB A;  1MAT A;  2GU5 A;  5CIK A;  5FCF A;  3IG4 A;  1XNZ A;  2GG9 A;  3PKE A;  1YW9 A;  1Y1N A;  1XGS A;  3BIQ A;  3FMR A;  2EVC A;  3RVA A;  1C21 A;  2P9A A;  4FLI A;  4S2T P;  4IPA A;  4U73 A;  1B59 A;  4RZZ A;  2GU6 A;  3S6B A;  4FO7 A;  4JUQ A;  2Q92 A;  5JFR A;  1A16 A;  1WL6 A;  2BN7 A;  3BIT A;  2GZ5 A;  2HOW A;  3PKA A;  4B28 A;  4FUK A;  1W2M A;  1JAW A;  2BWS A;  2DFI A;  1BN5 A;  4U76 A;  3MAT A;  4IEC A;  1XGM A;  1C23 A;  2G6P A;  4U71 A;  2OKN A;  1C22 A;  2BWU A;  1C27 A;  2GG8 A;  3BIP A;  2IW2 A;  2EVM A;  2V6C A;  4U6Z A;  4IKS A;  3D27 A;  4OOK A;  2GTX A;  2BHC A;  4A6V A;  1WBQ A;  1XGO A;  5CDL A;  2P98 A;  4ZWU A;  4MAT A;  2BWT A;  3CB6 A;  5CNX A;  3PKD A;  4U75 A;  2BWY A;  4S00 A;  1XGN A;  1R5H A;  4IDY A;  3IU8 A;  4FO8 A;  1PV9 A;  3MX6 A;  3FMQ A;  2Q96 A;  5D6E A;  1KQ0 A;  4PV4 A;  2OAZ A;  5D6F A;  1KP0 A;  2Q95 A;  2GG3 A;  2GGB A;  4U6W A;  2BHA A;  4S01 A;  2Q8K A;  2B3L A;  4IU6 A;  4U6E A;  1QXZ A;  2GU7 A;  4Z7M A;  1B6A A;  4ZWO A;  4EGE A;  5FCH A;  3FM3 A;  1WL9 A;  2BH3 A;  3IU9 A;  4ZWP A;  2GG5 A;  2EA2 A;  1WLR A;  4PNC A;  5CE6 A;  2GG0 A;  1YW8 A;  2ADU A;  4R60 A;  3PKC A;  4RZY A;  3ROR A;  4RGZ 1;  3Q6D A;  4FLK A;  2B3K A;  3L24 A;  1BOA A;  1C24 A;  1CHM A;  2BHB A;  1O0X A;  2V3X A;  1QXW A;  3IU7 A;  4FLL A;  1WY2 A;  1R5G A;  1YW7 A;  2B3H A;  4U69 A;  5JHU A;  2GG7 A;  2BWV A;  1N51 A;  2BWW A;  1KQ9 A;  4IKT A;  4QR8 A;  5CDE A;  2NQ7 A;  3CB5 A;  5E5B A;  2MAT A;  2EVO A;  2V3Y A;  2GG2 A;  4U6C A;  2BB7 A;  3L7G A;  1YJ3 A;  2NQ6 A;  3CTZ A;  1WKM A;  4IKU A;  4KM3 A;  4ZNG A;  2BWX A;  3TB5 A;  2BHD A;  4FKC A;  4A6W A;  4IF7 A;  1R58 A;  4U1B A;  5CDV A;  2P99 A;  4FLJ A;  1QXY A;  2GU4 A;  2Q94 A;  2ZSG A;  1YVM A;  2GA2 A;  4U6J A;  2V3Z A;  4U70 A;  3MR1 A;  2GGC A;  1QZY A;  2Q93 A;  3TAV A;  1WN1 A;  4HXX A;  2EA4 A;  4IKR A;  4S2R P;  5CLS A;  5JI6 A;  1W7V A;  1M35 A; 
#chains in the Genus database with same CATH topology
 3PKB A;  1MAT A;  2GU5 A;  5CIK A;  5FCF A;  3IG4 A;  1XNZ A;  2GG9 A;  3PKE A;  1YW9 A;  1Y1N A;  1XGS A;  3BIQ A;  3FMR A;  2EVC A;  3RVA A;  1C21 A;  2P9A A;  4FLI A;  4S2T P;  4IPA A;  4U73 A;  1B59 A;  4RZZ A;  2GU6 A;  3S6B A;  4FO7 A;  4JUQ A;  2Q92 A;  5JFR A;  1A16 A;  1WL6 A;  2BN7 A;  3BIT A;  2GZ5 A;  2HOW A;  3PKA A;  4B28 A;  4FUK A;  1W2M A;  1JAW A;  2BWS A;  2DFI A;  1BN5 A;  4U76 A;  3MAT A;  4IEC A;  1XGM A;  1C23 A;  2G6P A;  4U71 A;  2OKN A;  1C22 A;  2BWU A;  1C27 A;  2GG8 A;  3BIP A;  2IW2 A;  2EVM A;  2V6C A;  4U6Z A;  4IKS A;  3D27 A;  4OOK A;  2GTX A;  2BHC A;  4A6V A;  1WBQ A;  1XGO A;  5CDL A;  2P98 A;  4ZWU A;  4MAT A;  2BWT A;  3CB6 A;  5CNX A;  3PKD A;  4U75 A;  2BWY A;  4S00 A;  1XGN A;  1R5H A;  4IDY A;  3IU8 A;  4FO8 A;  1PV9 A;  3MX6 A;  3FMQ A;  2Q96 A;  5D6E A;  1KQ0 A;  4PV4 A;  2OAZ A;  5D6F A;  1KP0 A;  2Q95 A;  2GG3 A;  2GGB A;  4U6W A;  2BHA A;  4S01 A;  2Q8K A;  2B3L A;  4IU6 A;  4U6E A;  1QXZ A;  2GU7 A;  4Z7M A;  1B6A A;  4ZWO A;  4EGE A;  5FCH A;  3FM3 A;  1WL9 A;  2BH3 A;  3IU9 A;  4ZWP A;  2GG5 A;  2EA2 A;  1WLR A;  4PNC A;  5CE6 A;  2GG0 A;  1YW8 A;  2ADU A;  4R60 A;  3PKC A;  4RZY A;  3ROR A;  4RGZ 1;  3Q6D A;  4FLK A;  2B3K A;  3L24 A;  1BOA A;  1C24 A;  1CHM A;  2BHB A;  1O0X A;  2V3X A;  1QXW A;  3IU7 A;  4FLL A;  1WY2 A;  1R5G A;  1YW7 A;  2B3H A;  4U69 A;  5JHU A;  2GG7 A;  2BWV A;  1N51 A;  2BWW A;  1KQ9 A;  4IKT A;  4QR8 A;  5CDE A;  2NQ7 A;  3CB5 A;  5E5B A;  2MAT A;  2EVO A;  2V3Y A;  2GG2 A;  4U6C A;  2BB7 A;  3L7G A;  1YJ3 A;  2NQ6 A;  3CTZ A;  1WKM A;  4IKU A;  4KM3 A;  4ZNG A;  2BWX A;  3TB5 A;  2BHD A;  4FKC A;  4A6W A;  4IF7 A;  1R58 A;  4U1B A;  5CDV A;  2P99 A;  4FLJ A;  1QXY A;  2GU4 A;  2Q94 A;  2ZSG A;  1YVM A;  2GA2 A;  4U6J A;  2V3Z A;  4U70 A;  3MR1 A;  2GGC A;  1QZY A;  2Q93 A;  3TAV A;  1WN1 A;  4HXX A;  2EA4 A;  4IKR A;  4S2R P;  5CLS A;  5JI6 A;  1W7V A;  1M35 A; 
#chains in the Genus database with same CATH homology
 3PKB A;  1MAT A;  2GU5 A;  5CIK A;  5FCF A;  3IG4 A;  1XNZ A;  2GG9 A;  3PKE A;  1YW9 A;  1Y1N A;  1XGS A;  3BIQ A;  3FMR A;  2EVC A;  3RVA A;  1C21 A;  2P9A A;  4FLI A;  4S2T P;  4IPA A;  4U73 A;  1B59 A;  4RZZ A;  2GU6 A;  3S6B A;  4FO7 A;  4JUQ A;  2Q92 A;  5JFR A;  1A16 A;  1WL6 A;  2BN7 A;  3BIT A;  2GZ5 A;  2HOW A;  3PKA A;  4B28 A;  4FUK A;  1W2M A;  1JAW A;  2BWS A;  2DFI A;  1BN5 A;  4U76 A;  3MAT A;  4IEC A;  1XGM A;  1C23 A;  2G6P A;  4U71 A;  2OKN A;  1C22 A;  2BWU A;  1C27 A;  2GG8 A;  3BIP A;  2IW2 A;  2EVM A;  2V6C A;  4U6Z A;  4IKS A;  3D27 A;  4OOK A;  2GTX A;  2BHC A;  4A6V A;  1WBQ A;  1XGO A;  5CDL A;  2P98 A;  4ZWU A;  4MAT A;  2BWT A;  3CB6 A;  5CNX A;  3PKD A;  4U75 A;  2BWY A;  4S00 A;  1XGN A;  1R5H A;  4IDY A;  3IU8 A;  4FO8 A;  1PV9 A;  3MX6 A;  3FMQ A;  2Q96 A;  5D6E A;  1KQ0 A;  4PV4 A;  2OAZ A;  5D6F A;  1KP0 A;  2Q95 A;  2GG3 A;  2GGB A;  4U6W A;  2BHA A;  4S01 A;  2Q8K A;  2B3L A;  4IU6 A;  4U6E A;  1QXZ A;  2GU7 A;  4Z7M A;  1B6A A;  4ZWO A;  4EGE A;  5FCH A;  3FM3 A;  1WL9 A;  2BH3 A;  3IU9 A;  4ZWP A;  2GG5 A;  2EA2 A;  1WLR A;  4PNC A;  5CE6 A;  2GG0 A;  1YW8 A;  2ADU A;  4R60 A;  3PKC A;  4RZY A;  3ROR A;  4RGZ 1;  3Q6D A;  4FLK A;  2B3K A;  3L24 A;  1BOA A;  1C24 A;  1CHM A;  2BHB A;  1O0X A;  2V3X A;  1QXW A;  3IU7 A;  4FLL A;  1WY2 A;  1R5G A;  1YW7 A;  2B3H A;  4U69 A;  5JHU A;  2GG7 A;  2BWV A;  1N51 A;  2BWW A;  1KQ9 A;  4IKT A;  4QR8 A;  5CDE A;  2NQ7 A;  3CB5 A;  5E5B A;  2MAT A;  2EVO A;  2V3Y A;  2GG2 A;  4U6C A;  2BB7 A;  3L7G A;  1YJ3 A;  2NQ6 A;  3CTZ A;  1WKM A;  4IKU A;  4KM3 A;  4ZNG A;  2BWX A;  3TB5 A;  2BHD A;  4FKC A;  4A6W A;  4IF7 A;  1R58 A;  4U1B A;  5CDV A;  2P99 A;  4FLJ A;  1QXY A;  2GU4 A;  2Q94 A;  2ZSG A;  1YVM A;  2GA2 A;  4U6J A;  2V3Z A;  4U70 A;  3MR1 A;  2GGC A;  1QZY A;  2Q93 A;  3TAV A;  1WN1 A;  4HXX A;  2EA4 A;  4IKR A;  4S2R P;  5CLS A;  5JI6 A;  1W7V A;  1M35 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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