3D27A

E. coli methionine aminopeptidase with fe inhibitor w29
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
pubmed doi rcsb
source organism Escherichia coli
total genus 83
structure length 261
sequence length 261
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2008-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3d27A00
3D27A 2B3LA 2GG8A 2Q93A 2ZSGA 4JUQA 1WLRA 2BWSA 2Q92A 2V3ZA 4S2RP 4Z7MA 1CHMA 2P9AA 3IU7A 4PV4A 4U6JA 2V3XA 3MR1A 5CE6A 2GG9A 2EVMA 2GG3A 3RORA 4R60A 1C21A 2P99A 4IU6A 4U1BA 1B59A 1QXYA 2GG0A 1R58A 3CTZA 3Q6DA 5CIKA 2GTXA 4S01A 1C23A 3PKAA 4IKTA 2HOWA 3PKEA 2Q95A 4IKUA 1WN1A 1Y1NA 1YW9A 1WY2A 2BN7A 3IU8A 4OOKA 2GU6A 2EA2A 1XGSA 2BWUA 2GU5A 3BIQA 2EVCA 5JFRA 4HXXA 2MATA 1QXZA 3RVAA 3CB6A 4RZYA 4FLKA 4U76A 1BN5A 4IECA 4IDYA 1WL9A 2GZ5A 4ZWOA 2EVOA 4RGZ1 1N51A 5JI6A 2G6PA 5D6EA 1YVMA 1O0XA 3IU9A 4QR8A 2BH3A 2DFIA 4FO8A 3BIPA 2BWXA 4U6ZA 1YW7A 2NQ7A 2Q94A 4U6WA 2BWTA 4KM3A 3PKDA 1R5GA 3PKCA 5CDEA 3PKBA 3CB5A 2BHCA 5CDLA 1KQ0A 1JAWA 4ZWUA 4IPAA 3L7GA 2ADUA 4S2TP 5CLSA 2Q96A 4MATA 1YJ3A 2BB7A 4EGEA 5FCHA 4A6WA 2GGCA 3FM3A 1XNZA 2GU4A 2IW2A 2BHDA 2P98A 1YW8A 1MATA 3MATA 4FLLA 1R5HA 1WL6A 5CNXA 4ZWPA 5D6FA 4FLIA 3MX6A 1B6AA 4PNCA 1M35A 1KP0A 3FMRA 5FCFA 2B3KA 2V6CA 4U70A 4FKCA 1XGOA 2B3HA 1XGNA 4U73A 2OAZA 2OKNA 2V3YA 1PV9A 4RZZA 2Q8KA 2NQ6A 5E5BA 5CDVA 3S6BA 2BWWA 1C24A 3FMQA 4FO7A 3TAVA 1W2MA 1BOAA 5JHUA 2BWYA 2GG7A 3TB5A 1QXWA 4U6EA 4IKRA 2BHBA 1C22A 4U71A 1WKMA 2BWVA 1W7VA 1QZYA 1WBQA 2GA2A 4ZNGA 1KQ9A 2GG2A 4IF7A 2GU7A 4U69A 1A16A 4FLJA 2BHAA 4U6CA 4U75A 1C27A 4S00A 1XGMA 2GG5A 4A6VA 4FUKA 3BITA 2GGBA 2EA4A 3IG4A 4B28A 3L24A 4IKSA
chains in the Genus database with same CATH superfamily
3D27A 2B3LA 2GG8A 2Q93A 2ZSGA 4JUQA 1WLRA 2BWSA 2Q92A 2V3ZA 4S2RP 4Z7MA 1CHMA 2P9AA 3IU7A 4PV4A 4U6JA 2V3XA 3MR1A 5CE6A 2GG9A 2EVMA 2GG3A 3RORA 4R60A 1C21A 2P99A 4IU6A 4U1BA 1B59A 1QXYA 2GG0A 1R58A 3CTZA 3Q6DA 5CIKA 2GTXA 4S01A 1C23A 3PKAA 4IKTA 2HOWA 3PKEA 2Q95A 4IKUA 1WN1A 1Y1NA 1YW9A 1WY2A 2BN7A 3IU8A 4OOKA 2GU6A 2EA2A 1XGSA 2BWUA 2GU5A 3BIQA 2EVCA 5JFRA 4HXXA 2MATA 1QXZA 3RVAA 3CB6A 4RZYA 4FLKA 4U76A 1BN5A 4IECA 4IDYA 1WL9A 2GZ5A 4ZWOA 2EVOA 4RGZ1 1N51A 5JI6A 2G6PA 5D6EA 1YVMA 1O0XA 3IU9A 4QR8A 2BH3A 2DFIA 4FO8A 3BIPA 2BWXA 4U6ZA 1YW7A 2NQ7A 2Q94A 4U6WA 2BWTA 4KM3A 3PKDA 1R5GA 3PKCA 5CDEA 3PKBA 3CB5A 2BHCA 5CDLA 1KQ0A 1JAWA 4ZWUA 4IPAA 3L7GA 2ADUA 4S2TP 5CLSA 2Q96A 4MATA 1YJ3A 2BB7A 4EGEA 5FCHA 4A6WA 2GGCA 3FM3A 1XNZA 2GU4A 2IW2A 2BHDA 2P98A 1YW8A 1MATA 3MATA 4FLLA 1R5HA 1WL6A 5CNXA 4ZWPA 5D6FA 4FLIA 3MX6A 1B6AA 4PNCA 1M35A 1KP0A 3FMRA 5FCFA 2B3KA 2V6CA 4U70A 4FKCA 1XGOA 2B3HA 1XGNA 4U73A 2OAZA 2OKNA 2V3YA 1PV9A 4RZZA 2Q8KA 2NQ6A 5E5BA 5CDVA 3S6BA 2BWWA 1C24A 3FMQA 4FO7A 3TAVA 1W2MA 1BOAA 5JHUA 2BWYA 2GG7A 3TB5A 1QXWA 4U6EA 4IKRA 2BHBA 1C22A 4U71A 1WKMA 2BWVA 1W7VA 1QZYA 1WBQA 2GA2A 4ZNGA 1KQ9A 2GG2A 4IF7A 2GU7A 4U69A 1A16A 4FLJA 2BHAA 4U6CA 4U75A 1C27A 4S00A 1XGMA 2GG5A 4A6VA 4FUKA 3BITA 2GGBA 2EA4A 3IG4A 4B28A 3L24A 4IKSA
chains in the Genus database with same CATH topology
3D27A 2B3LA 2GG8A 2Q93A 2ZSGA 4JUQA 1WLRA 2BWSA 2Q92A 2V3ZA 4S2RP 4Z7MA 1CHMA 2P9AA 3IU7A 4PV4A 4U6JA 2V3XA 3MR1A 5CE6A 2GG9A 2EVMA 2GG3A 3RORA 4R60A 1C21A 2P99A 4IU6A 4U1BA 1B59A 1QXYA 2GG0A 1R58A 3CTZA 3Q6DA 5CIKA 2GTXA 4S01A 1C23A 3PKAA 4IKTA 2HOWA 3PKEA 2Q95A 4IKUA 1WN1A 1Y1NA 1YW9A 1WY2A 2BN7A 3IU8A 4OOKA 2GU6A 2EA2A 1XGSA 2BWUA 2GU5A 3BIQA 2EVCA 5JFRA 4HXXA 2MATA 1QXZA 3RVAA 3CB6A 4RZYA 4FLKA 4U76A 1BN5A 4IECA 4IDYA 1WL9A 2GZ5A 4ZWOA 2EVOA 4RGZ1 1N51A 5JI6A 2G6PA 5D6EA 1YVMA 1O0XA 3IU9A 4QR8A 2BH3A 2DFIA 4FO8A 3BIPA 2BWXA 4U6ZA 1YW7A 2NQ7A 2Q94A 4U6WA 2BWTA 4KM3A 3PKDA 1R5GA 3PKCA 5CDEA 3PKBA 3CB5A 2BHCA 5CDLA 1KQ0A 1JAWA 4ZWUA 4IPAA 3L7GA 2ADUA 4S2TP 5CLSA 2Q96A 4MATA 1YJ3A 2BB7A 4EGEA 5FCHA 4A6WA 2GGCA 3FM3A 1XNZA 2GU4A 2IW2A 2BHDA 2P98A 1YW8A 1MATA 3MATA 4FLLA 1R5HA 1WL6A 5CNXA 4ZWPA 5D6FA 4FLIA 3MX6A 1B6AA 4PNCA 1M35A 1KP0A 3FMRA 5FCFA 2B3KA 2V6CA 4U70A 4FKCA 1XGOA 2B3HA 1XGNA 4U73A 2OAZA 2OKNA 2V3YA 1PV9A 4RZZA 2Q8KA 2NQ6A 5E5BA 5CDVA 3S6BA 2BWWA 1C24A 3FMQA 4FO7A 3TAVA 1W2MA 1BOAA 5JHUA 2BWYA 2GG7A 3TB5A 1QXWA 4U6EA 4IKRA 2BHBA 1C22A 4U71A 1WKMA 2BWVA 1W7VA 1QZYA 1WBQA 2GA2A 4ZNGA 1KQ9A 2GG2A 4IF7A 2GU7A 4U69A 1A16A 4FLJA 2BHAA 4U6CA 4U75A 1C27A 4S00A 1XGMA 2GG5A 4A6VA 4FUKA 3BITA 2GGBA 2EA4A 3IG4A 4B28A 3L24A 4IKSA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3D27 A;  2B3L A;  2GG8 A;  2Q93 A;  2ZSG A;  4JUQ A;  1WLR A;  2BWS A;  2Q92 A;  2V3Z A;  4S2R P;  4Z7M A;  1CHM A;  2P9A A;  3IU7 A;  4PV4 A;  4U6J A;  2V3X A;  3MR1 A;  5CE6 A;  2GG9 A;  2EVM A;  2GG3 A;  3ROR A;  4R60 A;  1C21 A;  2P99 A;  4IU6 A;  4U1B A;  1B59 A;  1QXY A;  2GG0 A;  1R58 A;  3CTZ A;  3Q6D A;  5CIK A;  2GTX A;  4S01 A;  1C23 A;  3PKA A;  4IKT A;  2HOW A;  3PKE A;  2Q95 A;  4IKU A;  1WN1 A;  1Y1N A;  1YW9 A;  1WY2 A;  2BN7 A;  3IU8 A;  4OOK A;  2GU6 A;  2EA2 A;  1XGS A;  2BWU A;  2GU5 A;  3BIQ A;  2EVC A;  5JFR A;  4HXX A;  2MAT A;  1QXZ A;  3RVA A;  3CB6 A;  4RZY A;  4FLK A;  4U76 A;  1BN5 A;  4IEC A;  4IDY A;  1WL9 A;  2GZ5 A;  4ZWO A;  2EVO A;  4RGZ 1;  1N51 A;  5JI6 A;  2G6P A;  5D6E A;  1YVM A;  1O0X A;  3IU9 A;  4QR8 A;  2BH3 A;  2DFI A;  4FO8 A;  3BIP A;  2BWX A;  4U6Z A;  1YW7 A;  2NQ7 A;  2Q94 A;  4U6W A;  2BWT A;  4KM3 A;  3PKD A;  1R5G A;  3PKC A;  5CDE A;  3PKB A;  3CB5 A;  2BHC A;  5CDL A;  1KQ0 A;  1JAW A;  4ZWU A;  4IPA A;  3L7G A;  2ADU A;  4S2T P;  5CLS A;  2Q96 A;  4MAT A;  1YJ3 A;  2BB7 A;  4EGE A;  5FCH A;  4A6W A;  2GGC A;  3FM3 A;  1XNZ A;  2GU4 A;  2IW2 A;  2BHD A;  2P98 A;  1YW8 A;  1MAT A;  3MAT A;  4FLL A;  1R5H A;  1WL6 A;  5CNX A;  4ZWP A;  5D6F A;  4FLI A;  3MX6 A;  1B6A A;  4PNC A;  1M35 A;  1KP0 A;  3FMR A;  5FCF A;  2B3K A;  2V6C A;  4U70 A;  4FKC A;  1XGO A;  2B3H A;  1XGN A;  4U73 A;  2OAZ A;  2OKN A;  2V3Y A;  1PV9 A;  4RZZ A;  2Q8K A;  2NQ6 A;  5E5B A;  5CDV A;  3S6B A;  2BWW A;  1C24 A;  3FMQ A;  4FO7 A;  3TAV A;  1W2M A;  1BOA A;  5JHU A;  2BWY A;  2GG7 A;  3TB5 A;  1QXW A;  4U6E A;  4IKR A;  2BHB A;  1C22 A;  4U71 A;  1WKM A;  2BWV A;  1W7V A;  1QZY A;  1WBQ A;  2GA2 A;  4ZNG A;  1KQ9 A;  2GG2 A;  4IF7 A;  2GU7 A;  4U69 A;  1A16 A;  4FLJ A;  2BHA A;  4U6C A;  4U75 A;  1C27 A;  4S00 A;  1XGM A;  2GG5 A;  4A6V A;  4FUK A;  3BIT A;  2GGB A;  2EA4 A;  3IG4 A;  4B28 A;  3L24 A;  4IKS A; 
#chains in the Genus database with same CATH topology
 3D27 A;  2B3L A;  2GG8 A;  2Q93 A;  2ZSG A;  4JUQ A;  1WLR A;  2BWS A;  2Q92 A;  2V3Z A;  4S2R P;  4Z7M A;  1CHM A;  2P9A A;  3IU7 A;  4PV4 A;  4U6J A;  2V3X A;  3MR1 A;  5CE6 A;  2GG9 A;  2EVM A;  2GG3 A;  3ROR A;  4R60 A;  1C21 A;  2P99 A;  4IU6 A;  4U1B A;  1B59 A;  1QXY A;  2GG0 A;  1R58 A;  3CTZ A;  3Q6D A;  5CIK A;  2GTX A;  4S01 A;  1C23 A;  3PKA A;  4IKT A;  2HOW A;  3PKE A;  2Q95 A;  4IKU A;  1WN1 A;  1Y1N A;  1YW9 A;  1WY2 A;  2BN7 A;  3IU8 A;  4OOK A;  2GU6 A;  2EA2 A;  1XGS A;  2BWU A;  2GU5 A;  3BIQ A;  2EVC A;  5JFR A;  4HXX A;  2MAT A;  1QXZ A;  3RVA A;  3CB6 A;  4RZY A;  4FLK A;  4U76 A;  1BN5 A;  4IEC A;  4IDY A;  1WL9 A;  2GZ5 A;  4ZWO A;  2EVO A;  4RGZ 1;  1N51 A;  5JI6 A;  2G6P A;  5D6E A;  1YVM A;  1O0X A;  3IU9 A;  4QR8 A;  2BH3 A;  2DFI A;  4FO8 A;  3BIP A;  2BWX A;  4U6Z A;  1YW7 A;  2NQ7 A;  2Q94 A;  4U6W A;  2BWT A;  4KM3 A;  3PKD A;  1R5G A;  3PKC A;  5CDE A;  3PKB A;  3CB5 A;  2BHC A;  5CDL A;  1KQ0 A;  1JAW A;  4ZWU A;  4IPA A;  3L7G A;  2ADU A;  4S2T P;  5CLS A;  2Q96 A;  4MAT A;  1YJ3 A;  2BB7 A;  4EGE A;  5FCH A;  4A6W A;  2GGC A;  3FM3 A;  1XNZ A;  2GU4 A;  2IW2 A;  2BHD A;  2P98 A;  1YW8 A;  1MAT A;  3MAT A;  4FLL A;  1R5H A;  1WL6 A;  5CNX A;  4ZWP A;  5D6F A;  4FLI A;  3MX6 A;  1B6A A;  4PNC A;  1M35 A;  1KP0 A;  3FMR A;  5FCF A;  2B3K A;  2V6C A;  4U70 A;  4FKC A;  1XGO A;  2B3H A;  1XGN A;  4U73 A;  2OAZ A;  2OKN A;  2V3Y A;  1PV9 A;  4RZZ A;  2Q8K A;  2NQ6 A;  5E5B A;  5CDV A;  3S6B A;  2BWW A;  1C24 A;  3FMQ A;  4FO7 A;  3TAV A;  1W2M A;  1BOA A;  5JHU A;  2BWY A;  2GG7 A;  3TB5 A;  1QXW A;  4U6E A;  4IKR A;  2BHB A;  1C22 A;  4U71 A;  1WKM A;  2BWV A;  1W7V A;  1QZY A;  1WBQ A;  2GA2 A;  4ZNG A;  1KQ9 A;  2GG2 A;  4IF7 A;  2GU7 A;  4U69 A;  1A16 A;  4FLJ A;  2BHA A;  4U6C A;  4U75 A;  1C27 A;  4S00 A;  1XGM A;  2GG5 A;  4A6V A;  4FUK A;  3BIT A;  2GGB A;  2EA4 A;  3IG4 A;  4B28 A;  3L24 A;  4IKS A; 
#chains in the Genus database with same CATH homology
 3D27 A;  2B3L A;  2GG8 A;  2Q93 A;  2ZSG A;  4JUQ A;  1WLR A;  2BWS A;  2Q92 A;  2V3Z A;  4S2R P;  4Z7M A;  1CHM A;  2P9A A;  3IU7 A;  4PV4 A;  4U6J A;  2V3X A;  3MR1 A;  5CE6 A;  2GG9 A;  2EVM A;  2GG3 A;  3ROR A;  4R60 A;  1C21 A;  2P99 A;  4IU6 A;  4U1B A;  1B59 A;  1QXY A;  2GG0 A;  1R58 A;  3CTZ A;  3Q6D A;  5CIK A;  2GTX A;  4S01 A;  1C23 A;  3PKA A;  4IKT A;  2HOW A;  3PKE A;  2Q95 A;  4IKU A;  1WN1 A;  1Y1N A;  1YW9 A;  1WY2 A;  2BN7 A;  3IU8 A;  4OOK A;  2GU6 A;  2EA2 A;  1XGS A;  2BWU A;  2GU5 A;  3BIQ A;  2EVC A;  5JFR A;  4HXX A;  2MAT A;  1QXZ A;  3RVA A;  3CB6 A;  4RZY A;  4FLK A;  4U76 A;  1BN5 A;  4IEC A;  4IDY A;  1WL9 A;  2GZ5 A;  4ZWO A;  2EVO A;  4RGZ 1;  1N51 A;  5JI6 A;  2G6P A;  5D6E A;  1YVM A;  1O0X A;  3IU9 A;  4QR8 A;  2BH3 A;  2DFI A;  4FO8 A;  3BIP A;  2BWX A;  4U6Z A;  1YW7 A;  2NQ7 A;  2Q94 A;  4U6W A;  2BWT A;  4KM3 A;  3PKD A;  1R5G A;  3PKC A;  5CDE A;  3PKB A;  3CB5 A;  2BHC A;  5CDL A;  1KQ0 A;  1JAW A;  4ZWU A;  4IPA A;  3L7G A;  2ADU A;  4S2T P;  5CLS A;  2Q96 A;  4MAT A;  1YJ3 A;  2BB7 A;  4EGE A;  5FCH A;  4A6W A;  2GGC A;  3FM3 A;  1XNZ A;  2GU4 A;  2IW2 A;  2BHD A;  2P98 A;  1YW8 A;  1MAT A;  3MAT A;  4FLL A;  1R5H A;  1WL6 A;  5CNX A;  4ZWP A;  5D6F A;  4FLI A;  3MX6 A;  1B6A A;  4PNC A;  1M35 A;  1KP0 A;  3FMR A;  5FCF A;  2B3K A;  2V6C A;  4U70 A;  4FKC A;  1XGO A;  2B3H A;  1XGN A;  4U73 A;  2OAZ A;  2OKN A;  2V3Y A;  1PV9 A;  4RZZ A;  2Q8K A;  2NQ6 A;  5E5B A;  5CDV A;  3S6B A;  2BWW A;  1C24 A;  3FMQ A;  4FO7 A;  3TAV A;  1W2M A;  1BOA A;  5JHU A;  2BWY A;  2GG7 A;  3TB5 A;  1QXW A;  4U6E A;  4IKR A;  2BHB A;  1C22 A;  4U71 A;  1WKM A;  2BWV A;  1W7V A;  1QZY A;  1WBQ A;  2GA2 A;  4ZNG A;  1KQ9 A;  2GG2 A;  4IF7 A;  2GU7 A;  4U69 A;  1A16 A;  4FLJ A;  2BHA A;  4U6C A;  4U75 A;  1C27 A;  4S00 A;  1XGM A;  2GG5 A;  4A6V A;  4FUK A;  3BIT A;  2GGB A;  2EA4 A;  3IG4 A;  4B28 A;  3L24 A;  4IKS A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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