3TAVA

Crystal structure of a methionine aminopeptidase from mycobacterium abscessus
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
264
structure length
264
Chain Sequence
VGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDGSRAAHWEHTVAVTEAGPRILTMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium abscessus
total genus 82
structure length 264
sequence length 264
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tavA00
2BWYA 1WL6A 2GTXA 2V3ZA 3L7GA 1R5GA 5CDEA 3CB5A 4A6WA 1N51A 2OAZA 1XGNA 4FO7A 4FO8A 4U71A 2GG8A 4U6WA 4IECA 2GU7A 4IU6A 2ADUA 2V3YA 4IF7A 4IKUA 4OOKA 2BWXA 3RVAA 4IKTA 4U1BA 5D6FA 2EVMA 3MR1A 1Y1NA 2B3LA 2DFIA 2GGBA 2OKNA 4ZWOA 4FKCA 2B3KA 2Q95A 1YW7A 1A16A 3FM3A 5CNXA 2BWVA 4HXXA 5CIKA 2BWWA 1YVMA 4ZNGA 2GG5A 5CDVA 1C21A 4FUKA 3IU8A 1KQ0A 4U69A 2P98A 2Q96A 2BWTA 1YJ3A 3CTZA 3TAVA 2GZ5A 2BB7A 1M35A 2GGCA 4FLIA 5CDLA 5FCHA 3S6BA 3CB6A 1JAWA 1B59A 1KQ9A 2Q92A 1KP0A 2Q94A 2GU5A 2GG9A 2GG3A 4PV4A 2Q8KA 4JUQA 5FCFA 5D6EA 2EVCA 5JI6A 1XGMA 1WY2A 1R58A 4ZWUA 2BN7A 1XGOA 4U6EA 4U73A 2GU4A 3PKAA 3Q6DA 3D27A 3MX6A 3RORA 2GU6A 1QXWA 2BWSA 2BHBA 4S2RP 1QXZA 1WL9A 4U75A 4B28A 1CHMA 4KM3A 3MATA 2P9AA 2V6CA 2NQ7A 4IDYA 2BHAA 4RGZ1 5CE6A 2G6PA 2EA4A 3FMRA 1C22A 4U70A 1XGSA 4ZWPA 1MATA 4R60A 1WLRA 4S2TP 1C23A 1W7VA 2BH3A 4FLLA 4U6CA 4U76A 2IW2A 2GG7A 3IU7A 4MATA 2BWUA 4FLKA 1WBQA 4S01A 4S00A 4A6VA 3BIQA 2B3HA 2ZSGA 4Z7MA 2V3XA 5JHUA 1C27A 2GA2A 4RZZA 5E5BA 2HOWA 1WKMA 1YW9A 3IU9A 2BHCA 4IKSA 4IPAA 3FMQA 3IG4A 5CLSA 3PKCA 1BOAA 1B6AA 4FLJA 2EVOA 3PKEA 4RZYA 1O0XA 2NQ6A 4QR8A 5JFRA 4EGEA 2EA2A 1XNZA 2BHDA 2Q93A 1R5HA 1BN5A 2P99A 1QXYA 4U6JA 1PV9A 3BITA 2MATA 4U6ZA 1QZYA 1YW8A 4IKRA 1C24A 4PNCA 1W2MA 3L24A 3BIPA 3PKBA 3TB5A 2GG0A 3PKDA 1WN1A 2GG2A
chains in the Genus database with same CATH superfamily
2BWYA 1WL6A 2GTXA 2V3ZA 3L7GA 1R5GA 5CDEA 3CB5A 4A6WA 1N51A 2OAZA 1XGNA 4FO7A 4FO8A 4U71A 2GG8A 4U6WA 4IECA 2GU7A 4IU6A 2ADUA 2V3YA 4IF7A 4IKUA 4OOKA 2BWXA 3RVAA 4IKTA 4U1BA 5D6FA 2EVMA 3MR1A 1Y1NA 2B3LA 2DFIA 2GGBA 2OKNA 4ZWOA 4FKCA 2B3KA 2Q95A 1YW7A 1A16A 3FM3A 5CNXA 2BWVA 4HXXA 5CIKA 2BWWA 1YVMA 4ZNGA 2GG5A 5CDVA 1C21A 4FUKA 3IU8A 1KQ0A 4U69A 2P98A 2Q96A 2BWTA 1YJ3A 3CTZA 3TAVA 2GZ5A 2BB7A 1M35A 2GGCA 4FLIA 5CDLA 5FCHA 3S6BA 3CB6A 1JAWA 1B59A 1KQ9A 2Q92A 1KP0A 2Q94A 2GU5A 2GG9A 2GG3A 4PV4A 2Q8KA 4JUQA 5FCFA 5D6EA 2EVCA 5JI6A 1XGMA 1WY2A 1R58A 4ZWUA 2BN7A 1XGOA 4U6EA 4U73A 2GU4A 3PKAA 3Q6DA 3D27A 3MX6A 3RORA 2GU6A 1QXWA 2BWSA 2BHBA 4S2RP 1QXZA 1WL9A 4U75A 4B28A 1CHMA 4KM3A 3MATA 2P9AA 2V6CA 2NQ7A 4IDYA 2BHAA 4RGZ1 5CE6A 2G6PA 2EA4A 3FMRA 1C22A 4U70A 1XGSA 4ZWPA 1MATA 4R60A 1WLRA 4S2TP 1C23A 1W7VA 2BH3A 4FLLA 4U6CA 4U76A 2IW2A 2GG7A 3IU7A 4MATA 2BWUA 4FLKA 1WBQA 4S01A 4S00A 4A6VA 3BIQA 2B3HA 2ZSGA 4Z7MA 2V3XA 5JHUA 1C27A 2GA2A 4RZZA 5E5BA 2HOWA 1WKMA 1YW9A 3IU9A 2BHCA 4IKSA 4IPAA 3FMQA 3IG4A 5CLSA 3PKCA 1BOAA 1B6AA 4FLJA 2EVOA 3PKEA 4RZYA 1O0XA 2NQ6A 4QR8A 5JFRA 4EGEA 2EA2A 1XNZA 2BHDA 2Q93A 1R5HA 1BN5A 2P99A 1QXYA 4U6JA 1PV9A 3BITA 2MATA 4U6ZA 1QZYA 1YW8A 4IKRA 1C24A 4PNCA 1W2MA 3L24A 3BIPA 3PKBA 3TB5A 2GG0A 3PKDA 1WN1A 2GG2A
chains in the Genus database with same CATH topology
2BWYA 1WL6A 2GTXA 2V3ZA 3L7GA 1R5GA 5CDEA 3CB5A 4A6WA 1N51A 2OAZA 1XGNA 4FO7A 4FO8A 4U71A 2GG8A 4U6WA 4IECA 2GU7A 4IU6A 2ADUA 2V3YA 4IF7A 4IKUA 4OOKA 2BWXA 3RVAA 4IKTA 4U1BA 5D6FA 2EVMA 3MR1A 1Y1NA 2B3LA 2DFIA 2GGBA 2OKNA 4ZWOA 4FKCA 2B3KA 2Q95A 1YW7A 1A16A 3FM3A 5CNXA 2BWVA 4HXXA 5CIKA 2BWWA 1YVMA 4ZNGA 2GG5A 5CDVA 1C21A 4FUKA 3IU8A 1KQ0A 4U69A 2P98A 2Q96A 2BWTA 1YJ3A 3CTZA 3TAVA 2GZ5A 2BB7A 1M35A 2GGCA 4FLIA 5CDLA 5FCHA 3S6BA 3CB6A 1JAWA 1B59A 1KQ9A 2Q92A 1KP0A 2Q94A 2GU5A 2GG9A 2GG3A 4PV4A 2Q8KA 4JUQA 5FCFA 5D6EA 2EVCA 5JI6A 1XGMA 1WY2A 1R58A 4ZWUA 2BN7A 1XGOA 4U6EA 4U73A 2GU4A 3PKAA 3Q6DA 3D27A 3MX6A 3RORA 2GU6A 1QXWA 2BWSA 2BHBA 4S2RP 1QXZA 1WL9A 4U75A 4B28A 1CHMA 4KM3A 3MATA 2P9AA 2V6CA 2NQ7A 4IDYA 2BHAA 4RGZ1 5CE6A 2G6PA 2EA4A 3FMRA 1C22A 4U70A 1XGSA 4ZWPA 1MATA 4R60A 1WLRA 4S2TP 1C23A 1W7VA 2BH3A 4FLLA 4U6CA 4U76A 2IW2A 2GG7A 3IU7A 4MATA 2BWUA 4FLKA 1WBQA 4S01A 4S00A 4A6VA 3BIQA 2B3HA 2ZSGA 4Z7MA 2V3XA 5JHUA 1C27A 2GA2A 4RZZA 5E5BA 2HOWA 1WKMA 1YW9A 3IU9A 2BHCA 4IKSA 4IPAA 3FMQA 3IG4A 5CLSA 3PKCA 1BOAA 1B6AA 4FLJA 2EVOA 3PKEA 4RZYA 1O0XA 2NQ6A 4QR8A 5JFRA 4EGEA 2EA2A 1XNZA 2BHDA 2Q93A 1R5HA 1BN5A 2P99A 1QXYA 4U6JA 1PV9A 3BITA 2MATA 4U6ZA 1QZYA 1YW8A 4IKRA 1C24A 4PNCA 1W2MA 3L24A 3BIPA 3PKBA 3TB5A 2GG0A 3PKDA 1WN1A 2GG2A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2BWY A;  1WL6 A;  2GTX A;  2V3Z A;  3L7G A;  1R5G A;  5CDE A;  3CB5 A;  4A6W A;  1N51 A;  2OAZ A;  1XGN A;  4FO7 A;  4FO8 A;  4U71 A;  2GG8 A;  4U6W A;  4IEC A;  2GU7 A;  4IU6 A;  2ADU A;  2V3Y A;  4IF7 A;  4IKU A;  4OOK A;  2BWX A;  3RVA A;  4IKT A;  4U1B A;  5D6F A;  2EVM A;  3MR1 A;  1Y1N A;  2B3L A;  2DFI A;  2GGB A;  2OKN A;  4ZWO A;  4FKC A;  2B3K A;  2Q95 A;  1YW7 A;  1A16 A;  3FM3 A;  5CNX A;  2BWV A;  4HXX A;  5CIK A;  2BWW A;  1YVM A;  4ZNG A;  2GG5 A;  5CDV A;  1C21 A;  4FUK A;  3IU8 A;  1KQ0 A;  4U69 A;  2P98 A;  2Q96 A;  2BWT A;  1YJ3 A;  3CTZ A;  3TAV A;  2GZ5 A;  2BB7 A;  1M35 A;  2GGC A;  4FLI A;  5CDL A;  5FCH A;  3S6B A;  3CB6 A;  1JAW A;  1B59 A;  1KQ9 A;  2Q92 A;  1KP0 A;  2Q94 A;  2GU5 A;  2GG9 A;  2GG3 A;  4PV4 A;  2Q8K A;  4JUQ A;  5FCF A;  5D6E A;  2EVC A;  5JI6 A;  1XGM A;  1WY2 A;  1R58 A;  4ZWU A;  2BN7 A;  1XGO A;  4U6E A;  4U73 A;  2GU4 A;  3PKA A;  3Q6D A;  3D27 A;  3MX6 A;  3ROR A;  2GU6 A;  1QXW A;  2BWS A;  2BHB A;  4S2R P;  1QXZ A;  1WL9 A;  4U75 A;  4B28 A;  1CHM A;  4KM3 A;  3MAT A;  2P9A A;  2V6C A;  2NQ7 A;  4IDY A;  2BHA A;  4RGZ 1;  5CE6 A;  2G6P A;  2EA4 A;  3FMR A;  1C22 A;  4U70 A;  1XGS A;  4ZWP A;  1MAT A;  4R60 A;  1WLR A;  4S2T P;  1C23 A;  1W7V A;  2BH3 A;  4FLL A;  4U6C A;  4U76 A;  2IW2 A;  2GG7 A;  3IU7 A;  4MAT A;  2BWU A;  4FLK A;  1WBQ A;  4S01 A;  4S00 A;  4A6V A;  3BIQ A;  2B3H A;  2ZSG A;  4Z7M A;  2V3X A;  5JHU A;  1C27 A;  2GA2 A;  4RZZ A;  5E5B A;  2HOW A;  1WKM A;  1YW9 A;  3IU9 A;  2BHC A;  4IKS A;  4IPA A;  3FMQ A;  3IG4 A;  5CLS A;  3PKC A;  1BOA A;  1B6A A;  4FLJ A;  2EVO A;  3PKE A;  4RZY A;  1O0X A;  2NQ6 A;  4QR8 A;  5JFR A;  4EGE A;  2EA2 A;  1XNZ A;  2BHD A;  2Q93 A;  1R5H A;  1BN5 A;  2P99 A;  1QXY A;  4U6J A;  1PV9 A;  3BIT A;  2MAT A;  4U6Z A;  1QZY A;  1YW8 A;  4IKR A;  1C24 A;  4PNC A;  1W2M A;  3L24 A;  3BIP A;  3PKB A;  3TB5 A;  2GG0 A;  3PKD A;  1WN1 A;  2GG2 A; 
#chains in the Genus database with same CATH topology
 2BWY A;  1WL6 A;  2GTX A;  2V3Z A;  3L7G A;  1R5G A;  5CDE A;  3CB5 A;  4A6W A;  1N51 A;  2OAZ A;  1XGN A;  4FO7 A;  4FO8 A;  4U71 A;  2GG8 A;  4U6W A;  4IEC A;  2GU7 A;  4IU6 A;  2ADU A;  2V3Y A;  4IF7 A;  4IKU A;  4OOK A;  2BWX A;  3RVA A;  4IKT A;  4U1B A;  5D6F A;  2EVM A;  3MR1 A;  1Y1N A;  2B3L A;  2DFI A;  2GGB A;  2OKN A;  4ZWO A;  4FKC A;  2B3K A;  2Q95 A;  1YW7 A;  1A16 A;  3FM3 A;  5CNX A;  2BWV A;  4HXX A;  5CIK A;  2BWW A;  1YVM A;  4ZNG A;  2GG5 A;  5CDV A;  1C21 A;  4FUK A;  3IU8 A;  1KQ0 A;  4U69 A;  2P98 A;  2Q96 A;  2BWT A;  1YJ3 A;  3CTZ A;  3TAV A;  2GZ5 A;  2BB7 A;  1M35 A;  2GGC A;  4FLI A;  5CDL A;  5FCH A;  3S6B A;  3CB6 A;  1JAW A;  1B59 A;  1KQ9 A;  2Q92 A;  1KP0 A;  2Q94 A;  2GU5 A;  2GG9 A;  2GG3 A;  4PV4 A;  2Q8K A;  4JUQ A;  5FCF A;  5D6E A;  2EVC A;  5JI6 A;  1XGM A;  1WY2 A;  1R58 A;  4ZWU A;  2BN7 A;  1XGO A;  4U6E A;  4U73 A;  2GU4 A;  3PKA A;  3Q6D A;  3D27 A;  3MX6 A;  3ROR A;  2GU6 A;  1QXW A;  2BWS A;  2BHB A;  4S2R P;  1QXZ A;  1WL9 A;  4U75 A;  4B28 A;  1CHM A;  4KM3 A;  3MAT A;  2P9A A;  2V6C A;  2NQ7 A;  4IDY A;  2BHA A;  4RGZ 1;  5CE6 A;  2G6P A;  2EA4 A;  3FMR A;  1C22 A;  4U70 A;  1XGS A;  4ZWP A;  1MAT A;  4R60 A;  1WLR A;  4S2T P;  1C23 A;  1W7V A;  2BH3 A;  4FLL A;  4U6C A;  4U76 A;  2IW2 A;  2GG7 A;  3IU7 A;  4MAT A;  2BWU A;  4FLK A;  1WBQ A;  4S01 A;  4S00 A;  4A6V A;  3BIQ A;  2B3H A;  2ZSG A;  4Z7M A;  2V3X A;  5JHU A;  1C27 A;  2GA2 A;  4RZZ A;  5E5B A;  2HOW A;  1WKM A;  1YW9 A;  3IU9 A;  2BHC A;  4IKS A;  4IPA A;  3FMQ A;  3IG4 A;  5CLS A;  3PKC A;  1BOA A;  1B6A A;  4FLJ A;  2EVO A;  3PKE A;  4RZY A;  1O0X A;  2NQ6 A;  4QR8 A;  5JFR A;  4EGE A;  2EA2 A;  1XNZ A;  2BHD A;  2Q93 A;  1R5H A;  1BN5 A;  2P99 A;  1QXY A;  4U6J A;  1PV9 A;  3BIT A;  2MAT A;  4U6Z A;  1QZY A;  1YW8 A;  4IKR A;  1C24 A;  4PNC A;  1W2M A;  3L24 A;  3BIP A;  3PKB A;  3TB5 A;  2GG0 A;  3PKD A;  1WN1 A;  2GG2 A; 
#chains in the Genus database with same CATH homology
 2BWY A;  1WL6 A;  2GTX A;  2V3Z A;  3L7G A;  1R5G A;  5CDE A;  3CB5 A;  4A6W A;  1N51 A;  2OAZ A;  1XGN A;  4FO7 A;  4FO8 A;  4U71 A;  2GG8 A;  4U6W A;  4IEC A;  2GU7 A;  4IU6 A;  2ADU A;  2V3Y A;  4IF7 A;  4IKU A;  4OOK A;  2BWX A;  3RVA A;  4IKT A;  4U1B A;  5D6F A;  2EVM A;  3MR1 A;  1Y1N A;  2B3L A;  2DFI A;  2GGB A;  2OKN A;  4ZWO A;  4FKC A;  2B3K A;  2Q95 A;  1YW7 A;  1A16 A;  3FM3 A;  5CNX A;  2BWV A;  4HXX A;  5CIK A;  2BWW A;  1YVM A;  4ZNG A;  2GG5 A;  5CDV A;  1C21 A;  4FUK A;  3IU8 A;  1KQ0 A;  4U69 A;  2P98 A;  2Q96 A;  2BWT A;  1YJ3 A;  3CTZ A;  3TAV A;  2GZ5 A;  2BB7 A;  1M35 A;  2GGC A;  4FLI A;  5CDL A;  5FCH A;  3S6B A;  3CB6 A;  1JAW A;  1B59 A;  1KQ9 A;  2Q92 A;  1KP0 A;  2Q94 A;  2GU5 A;  2GG9 A;  2GG3 A;  4PV4 A;  2Q8K A;  4JUQ A;  5FCF A;  5D6E A;  2EVC A;  5JI6 A;  1XGM A;  1WY2 A;  1R58 A;  4ZWU A;  2BN7 A;  1XGO A;  4U6E A;  4U73 A;  2GU4 A;  3PKA A;  3Q6D A;  3D27 A;  3MX6 A;  3ROR A;  2GU6 A;  1QXW A;  2BWS A;  2BHB A;  4S2R P;  1QXZ A;  1WL9 A;  4U75 A;  4B28 A;  1CHM A;  4KM3 A;  3MAT A;  2P9A A;  2V6C A;  2NQ7 A;  4IDY A;  2BHA A;  4RGZ 1;  5CE6 A;  2G6P A;  2EA4 A;  3FMR A;  1C22 A;  4U70 A;  1XGS A;  4ZWP A;  1MAT A;  4R60 A;  1WLR A;  4S2T P;  1C23 A;  1W7V A;  2BH3 A;  4FLL A;  4U6C A;  4U76 A;  2IW2 A;  2GG7 A;  3IU7 A;  4MAT A;  2BWU A;  4FLK A;  1WBQ A;  4S01 A;  4S00 A;  4A6V A;  3BIQ A;  2B3H A;  2ZSG A;  4Z7M A;  2V3X A;  5JHU A;  1C27 A;  2GA2 A;  4RZZ A;  5E5B A;  2HOW A;  1WKM A;  1YW9 A;  3IU9 A;  2BHC A;  4IKS A;  4IPA A;  3FMQ A;  3IG4 A;  5CLS A;  3PKC A;  1BOA A;  1B6A A;  4FLJ A;  2EVO A;  3PKE A;  4RZY A;  1O0X A;  2NQ6 A;  4QR8 A;  5JFR A;  4EGE A;  2EA2 A;  1XNZ A;  2BHD A;  2Q93 A;  1R5H A;  1BN5 A;  2P99 A;  1QXY A;  4U6J A;  1PV9 A;  3BIT A;  2MAT A;  4U6Z A;  1QZY A;  1YW8 A;  4IKR A;  1C24 A;  4PNC A;  1W2M A;  3L24 A;  3BIP A;  3PKB A;  3TB5 A;  2GG0 A;  3PKD A;  1WN1 A;  2GG2 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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