4QR8A

Crystal structure of e coli pepq
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
441
structure length
441
Chain Sequence
SLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
publication title Structural basis of substrate selectivity of E. coli prolidase.
pubmed doi rcsb
source organism Escherichia coli
total genus 149
structure length 441
sequence length 441
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2014-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 4qr8A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4qr8A02
1WBQA 4FO8A 3IU8A 5CDLA 2Q92A 2BWUA 2EVCA 4RZZA 2V3YA 5CDEA 2V3ZA 4U6JA 2GU6A 4QR8A 4IKTA 4U75A 1BN5A 4IF7A 1XGNA 1YW9A 4B28A 1WY2A 2GG0A 1KQ0A 4U6CA 4U69A 2GG2A 4FLLA 4IU6A 3D27A 5JFRA 2GU4A 4S2RP 2ADUA 2BB7A 2P98A 4JUQA 2OKNA 1YW8A 5JHUA 5CDVA 5D6EA 4U1BA 2OAZA 2Q8KA 3S6BA 5FCHA 3PKDA 4U6EA 2GTXA 4U70A 4FLKA 1W7VA 2NQ7A 3FM3A 3IL0A 2BHDA 1C21A 3MATA 1KQ9A 2P99A 1B59A 4RGZ1 1WL6A 2BN7A 1B6AA 1QXZA 1YVMA 3RORA 4PV4A 5CE6A 2Q94A 3L24A 4FUKA 2IW2A 2GG7A 1WL9A 2B3LA 3CTZA 2Q95A 4ZWUA 1O0XA 5JI6A 1M35A 5CNXA 5E5BA 2GZ5A 2GG9A 3MR1A 1XNZA 3PN9A 4U76A 3FMQA 2BHAA 4S01A 2P9AA 2BWYA 2V3XA 2B3HA 2GU5A 4A6WA 3BIQA 1C22A 3PKEA 1XGMA 3CB5A 2G6PA 2BHBA 4RZYA 1C23A 2EVMA 4ZWPA 4IDYA 1KP0A 1C27A 5E2CA 4ZNGA 5CLSA 1CHMA 4FO7A 5CIKA 2GA2A 4IECA 3TAVA 2V6CA 2BWXA 4FLJA 1R5GA 3OVKA 4HXXA 1W2MA 4KM3A 1WLRA 3PKBA 1QZYA 1R5HA 4OOKA 2ZSGA 3PKAA 3PKCA 2GGCA 4EGEA 1A16A 2BWVA 4FLIA 4IKSA 4S2TP 4U6WA 3TB5A 2BWTA 1MATA 1R58A 1N51A 4S00A 2GU7A 1YW7A 4IPAA 2EA2A 2NQ6A 4PNCA 1WN1A 3RVAA 4U6ZA 4Z7MA 2Q93A 4MATA 3OOOA 2EVOA 1XGSA 3IU9A 1QXYA 4R60A 2GG5A 1JAWA 3CB6A 1WKMA 2MATA 5FCFA 4A6VA 4U71A 3PEBA 2BH3A 1BOAA 3FMRA 3QOCA 1C24A 2GG3A 1XGOA 2DFIA 3I7MA 3IG4A 2GG8A 3BITA 4IKUA 2EA4A 4ZWOA 3Q6DA 3IU7A 4FKCA 4IKRA 2B3KA 4U73A 5D6FA 2BWSA 2BWWA 3O5VA 1QXWA 2Q96A 3BIPA 1PV9A 1Y1NA 3L7GA 2GGBA 3MX6A 2BHCA 2HOWA 1YJ3A
chains in the Genus database with same CATH superfamily
1WBQA 4FO8A 3IU8A 5CDLA 2Q92A 2BWUA 2EVCA 4RZZA 2V3YA 5CDEA 2V3ZA 4U6JA 2GU6A 4QR8A 4IKTA 4U75A 1BN5A 4IF7A 1XGNA 1YW9A 4B28A 1WY2A 2GG0A 1KQ0A 4U6CA 4U69A 2GG2A 4FLLA 4IU6A 3D27A 5JFRA 2GU4A 4S2RP 2ADUA 2BB7A 2P98A 4JUQA 2OKNA 1YW8A 5JHUA 5CDVA 5D6EA 4U1BA 2OAZA 2Q8KA 3S6BA 5FCHA 3PKDA 4U6EA 2GTXA 4U70A 4FLKA 1W7VA 2NQ7A 3FM3A 3IL0A 2BHDA 1C21A 3MATA 1KQ9A 2P99A 1B59A 4RGZ1 1WL6A 2BN7A 1B6AA 1QXZA 1YVMA 3RORA 4PV4A 5CE6A 2Q94A 3L24A 4FUKA 2IW2A 2GG7A 1WL9A 2B3LA 3CTZA 2Q95A 4ZWUA 1O0XA 5JI6A 1M35A 5CNXA 5E5BA 2GZ5A 2GG9A 3MR1A 1XNZA 3PN9A 4U76A 3FMQA 2BHAA 4S01A 2P9AA 2BWYA 2V3XA 2B3HA 2GU5A 4A6WA 3BIQA 1C22A 3PKEA 1XGMA 3CB5A 2G6PA 2BHBA 4RZYA 1C23A 2EVMA 4ZWPA 4IDYA 1KP0A 1C27A 5E2CA 4ZNGA 5CLSA 1CHMA 4FO7A 5CIKA 2GA2A 4IECA 3TAVA 2V6CA 2BWXA 4FLJA 1R5GA 3OVKA 4HXXA 1W2MA 4KM3A 1WLRA 3PKBA 1QZYA 1R5HA 4OOKA 2ZSGA 3PKAA 3PKCA 2GGCA 4EGEA 1A16A 2BWVA 4FLIA 4IKSA 4S2TP 4U6WA 3TB5A 2BWTA 1MATA 1R58A 1N51A 4S00A 2GU7A 1YW7A 4IPAA 2EA2A 2NQ6A 4PNCA 1WN1A 3RVAA 4U6ZA 4Z7MA 2Q93A 4MATA 3OOOA 2EVOA 1XGSA 3IU9A 1QXYA 4R60A 2GG5A 1JAWA 3CB6A 1WKMA 2MATA 5FCFA 4A6VA 4U71A 3PEBA 2BH3A 1BOAA 3FMRA 3QOCA 1C24A 2GG3A 1XGOA 2DFIA 3I7MA 3IG4A 2GG8A 3BITA 4IKUA 2EA4A 4ZWOA 3Q6DA 3IU7A 4FKCA 4IKRA 2B3KA 4U73A 5D6FA 2BWSA 2BWWA 3O5VA 1QXWA 2Q96A 3BIPA 1PV9A 1Y1NA 3L7GA 2GGBA 3MX6A 2BHCA 2HOWA 1YJ3A
chains in the Genus database with same CATH topology
1WBQA 4FO8A 3IU8A 5CDLA 2Q92A 2BWUA 2EVCA 4RZZA 2V3YA 5CDEA 2V3ZA 4U6JA 2GU6A 4QR8A 4IKTA 4U75A 1BN5A 4IF7A 1XGNA 1YW9A 4B28A 1WY2A 2GG0A 1KQ0A 4U6CA 4U69A 2GG2A 4FLLA 4IU6A 3D27A 5JFRA 2GU4A 4S2RP 2ADUA 2BB7A 2P98A 4JUQA 2OKNA 1YW8A 5JHUA 5CDVA 5D6EA 4U1BA 2OAZA 2Q8KA 3S6BA 5FCHA 3PKDA 4U6EA 2GTXA 4U70A 4FLKA 1W7VA 2NQ7A 3FM3A 3IL0A 2BHDA 1C21A 3MATA 1KQ9A 2P99A 1B59A 4RGZ1 1WL6A 2BN7A 1B6AA 1QXZA 1YVMA 3RORA 4PV4A 5CE6A 2Q94A 3L24A 4FUKA 2IW2A 2GG7A 1WL9A 2B3LA 3CTZA 2Q95A 4ZWUA 1O0XA 5JI6A 1M35A 5CNXA 5E5BA 2GZ5A 2GG9A 3MR1A 1XNZA 3PN9A 4U76A 3FMQA 2BHAA 4S01A 2P9AA 2BWYA 2V3XA 2B3HA 2GU5A 4A6WA 3BIQA 1C22A 3PKEA 1XGMA 3CB5A 2G6PA 2BHBA 4RZYA 1C23A 2EVMA 4ZWPA 4IDYA 1KP0A 1C27A 5E2CA 4ZNGA 5CLSA 1CHMA 4FO7A 5CIKA 2GA2A 4IECA 3TAVA 2V6CA 2BWXA 4FLJA 1R5GA 3OVKA 4HXXA 1W2MA 4KM3A 1WLRA 3PKBA 1QZYA 1R5HA 4OOKA 2ZSGA 3PKAA 3PKCA 2GGCA 4EGEA 1A16A 2BWVA 4FLIA 4IKSA 4S2TP 4U6WA 3TB5A 2BWTA 1MATA 1R58A 1N51A 4S00A 2GU7A 1YW7A 4IPAA 2EA2A 2NQ6A 4PNCA 1WN1A 3RVAA 4U6ZA 4Z7MA 2Q93A 4MATA 3OOOA 2EVOA 1XGSA 3IU9A 1QXYA 4R60A 2GG5A 1JAWA 3CB6A 1WKMA 2MATA 5FCFA 4A6VA 4U71A 3PEBA 2BH3A 1BOAA 3FMRA 3QOCA 1C24A 2GG3A 1XGOA 2DFIA 3I7MA 3IG4A 2GG8A 3BITA 4IKUA 2EA4A 4ZWOA 3Q6DA 3IU7A 4FKCA 4IKRA 2B3KA 4U73A 5D6FA 2BWSA 2BWWA 3O5VA 1QXWA 2Q96A 3BIPA 1PV9A 1Y1NA 3L7GA 2GGBA 3MX6A 2BHCA 2HOWA 1YJ3A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1WBQ A;  4FO8 A;  3IU8 A;  5CDL A;  2Q92 A;  2BWU A;  2EVC A;  4RZZ A;  2V3Y A;  5CDE A;  2V3Z A;  4U6J A;  2GU6 A;  4QR8 A;  4IKT A;  4U75 A;  1BN5 A;  4IF7 A;  1XGN A;  1YW9 A;  4B28 A;  1WY2 A;  2GG0 A;  1KQ0 A;  4U6C A;  4U69 A;  2GG2 A;  4FLL A;  4IU6 A;  3D27 A;  5JFR A;  2GU4 A;  4S2R P;  2ADU A;  2BB7 A;  2P98 A;  4JUQ A;  2OKN A;  1YW8 A;  5JHU A;  5CDV A;  5D6E A;  4U1B A;  2OAZ A;  2Q8K A;  3S6B A;  5FCH A;  3PKD A;  4U6E A;  2GTX A;  4U70 A;  4FLK A;  1W7V A;  2NQ7 A;  3FM3 A;  3IL0 A;  2BHD A;  1C21 A;  3MAT A;  1KQ9 A;  2P99 A;  1B59 A;  4RGZ 1;  1WL6 A;  2BN7 A;  1B6A A;  1QXZ A;  1YVM A;  3ROR A;  4PV4 A;  5CE6 A;  2Q94 A;  3L24 A;  4FUK A;  2IW2 A;  2GG7 A;  1WL9 A;  2B3L A;  3CTZ A;  2Q95 A;  4ZWU A;  1O0X A;  5JI6 A;  1M35 A;  5CNX A;  5E5B A;  2GZ5 A;  2GG9 A;  3MR1 A;  1XNZ A;  3PN9 A;  4U76 A;  3FMQ A;  2BHA A;  4S01 A;  2P9A A;  2BWY A;  2V3X A;  2B3H A;  2GU5 A;  4A6W A;  3BIQ A;  1C22 A;  3PKE A;  1XGM A;  3CB5 A;  2G6P A;  2BHB A;  4RZY A;  1C23 A;  2EVM A;  4ZWP A;  4IDY A;  1KP0 A;  1C27 A;  5E2C A;  4ZNG A;  5CLS A;  1CHM A;  4FO7 A;  5CIK A;  2GA2 A;  4IEC A;  3TAV A;  2V6C A;  2BWX A;  4FLJ A;  1R5G A;  3OVK A;  4HXX A;  1W2M A;  4KM3 A;  1WLR A;  3PKB A;  1QZY A;  1R5H A;  4OOK A;  2ZSG A;  3PKA A;  3PKC A;  2GGC A;  4EGE A;  1A16 A;  2BWV A;  4FLI A;  4IKS A;  4S2T P;  4U6W A;  3TB5 A;  2BWT A;  1MAT A;  1R58 A;  1N51 A;  4S00 A;  2GU7 A;  1YW7 A;  4IPA A;  2EA2 A;  2NQ6 A;  4PNC A;  1WN1 A;  3RVA A;  4U6Z A;  4Z7M A;  2Q93 A;  4MAT A;  3OOO A;  2EVO A;  1XGS A;  3IU9 A;  1QXY A;  4R60 A;  2GG5 A;  1JAW A;  3CB6 A;  1WKM A;  2MAT A;  5FCF A;  4A6V A;  4U71 A;  3PEB A;  2BH3 A;  1BOA A;  3FMR A;  3QOC A;  1C24 A;  2GG3 A;  1XGO A;  2DFI A;  3I7M A;  3IG4 A;  2GG8 A;  3BIT A;  4IKU A;  2EA4 A;  4ZWO A;  3Q6D A;  3IU7 A;  4FKC A;  4IKR A;  2B3K A;  4U73 A;  5D6F A;  2BWS A;  2BWW A;  3O5V A;  1QXW A;  2Q96 A;  3BIP A;  1PV9 A;  1Y1N A;  3L7G A;  2GGB A;  3MX6 A;  2BHC A;  2HOW A;  1YJ3 A; 
#chains in the Genus database with same CATH topology
 1WBQ A;  4FO8 A;  3IU8 A;  5CDL A;  2Q92 A;  2BWU A;  2EVC A;  4RZZ A;  2V3Y A;  5CDE A;  2V3Z A;  4U6J A;  2GU6 A;  4QR8 A;  4IKT A;  4U75 A;  1BN5 A;  4IF7 A;  1XGN A;  1YW9 A;  4B28 A;  1WY2 A;  2GG0 A;  1KQ0 A;  4U6C A;  4U69 A;  2GG2 A;  4FLL A;  4IU6 A;  3D27 A;  5JFR A;  2GU4 A;  4S2R P;  2ADU A;  2BB7 A;  2P98 A;  4JUQ A;  2OKN A;  1YW8 A;  5JHU A;  5CDV A;  5D6E A;  4U1B A;  2OAZ A;  2Q8K A;  3S6B A;  5FCH A;  3PKD A;  4U6E A;  2GTX A;  4U70 A;  4FLK A;  1W7V A;  2NQ7 A;  3FM3 A;  3IL0 A;  2BHD A;  1C21 A;  3MAT A;  1KQ9 A;  2P99 A;  1B59 A;  4RGZ 1;  1WL6 A;  2BN7 A;  1B6A A;  1QXZ A;  1YVM A;  3ROR A;  4PV4 A;  5CE6 A;  2Q94 A;  3L24 A;  4FUK A;  2IW2 A;  2GG7 A;  1WL9 A;  2B3L A;  3CTZ A;  2Q95 A;  4ZWU A;  1O0X A;  5JI6 A;  1M35 A;  5CNX A;  5E5B A;  2GZ5 A;  2GG9 A;  3MR1 A;  1XNZ A;  3PN9 A;  4U76 A;  3FMQ A;  2BHA A;  4S01 A;  2P9A A;  2BWY A;  2V3X A;  2B3H A;  2GU5 A;  4A6W A;  3BIQ A;  1C22 A;  3PKE A;  1XGM A;  3CB5 A;  2G6P A;  2BHB A;  4RZY A;  1C23 A;  2EVM A;  4ZWP A;  4IDY A;  1KP0 A;  1C27 A;  5E2C A;  4ZNG A;  5CLS A;  1CHM A;  4FO7 A;  5CIK A;  2GA2 A;  4IEC A;  3TAV A;  2V6C A;  2BWX A;  4FLJ A;  1R5G A;  3OVK A;  4HXX A;  1W2M A;  4KM3 A;  1WLR A;  3PKB A;  1QZY A;  1R5H A;  4OOK A;  2ZSG A;  3PKA A;  3PKC A;  2GGC A;  4EGE A;  1A16 A;  2BWV A;  4FLI A;  4IKS A;  4S2T P;  4U6W A;  3TB5 A;  2BWT A;  1MAT A;  1R58 A;  1N51 A;  4S00 A;  2GU7 A;  1YW7 A;  4IPA A;  2EA2 A;  2NQ6 A;  4PNC A;  1WN1 A;  3RVA A;  4U6Z A;  4Z7M A;  2Q93 A;  4MAT A;  3OOO A;  2EVO A;  1XGS A;  3IU9 A;  1QXY A;  4R60 A;  2GG5 A;  1JAW A;  3CB6 A;  1WKM A;  2MAT A;  5FCF A;  4A6V A;  4U71 A;  3PEB A;  2BH3 A;  1BOA A;  3FMR A;  3QOC A;  1C24 A;  2GG3 A;  1XGO A;  2DFI A;  3I7M A;  3IG4 A;  2GG8 A;  3BIT A;  4IKU A;  2EA4 A;  4ZWO A;  3Q6D A;  3IU7 A;  4FKC A;  4IKR A;  2B3K A;  4U73 A;  5D6F A;  2BWS A;  2BWW A;  3O5V A;  1QXW A;  2Q96 A;  3BIP A;  1PV9 A;  1Y1N A;  3L7G A;  2GGB A;  3MX6 A;  2BHC A;  2HOW A;  1YJ3 A; 
#chains in the Genus database with same CATH homology
 1WBQ A;  4FO8 A;  3IU8 A;  5CDL A;  2Q92 A;  2BWU A;  2EVC A;  4RZZ A;  2V3Y A;  5CDE A;  2V3Z A;  4U6J A;  2GU6 A;  4QR8 A;  4IKT A;  4U75 A;  1BN5 A;  4IF7 A;  1XGN A;  1YW9 A;  4B28 A;  1WY2 A;  2GG0 A;  1KQ0 A;  4U6C A;  4U69 A;  2GG2 A;  4FLL A;  4IU6 A;  3D27 A;  5JFR A;  2GU4 A;  4S2R P;  2ADU A;  2BB7 A;  2P98 A;  4JUQ A;  2OKN A;  1YW8 A;  5JHU A;  5CDV A;  5D6E A;  4U1B A;  2OAZ A;  2Q8K A;  3S6B A;  5FCH A;  3PKD A;  4U6E A;  2GTX A;  4U70 A;  4FLK A;  1W7V A;  2NQ7 A;  3FM3 A;  3IL0 A;  2BHD A;  1C21 A;  3MAT A;  1KQ9 A;  2P99 A;  1B59 A;  4RGZ 1;  1WL6 A;  2BN7 A;  1B6A A;  1QXZ A;  1YVM A;  3ROR A;  4PV4 A;  5CE6 A;  2Q94 A;  3L24 A;  4FUK A;  2IW2 A;  2GG7 A;  1WL9 A;  2B3L A;  3CTZ A;  2Q95 A;  4ZWU A;  1O0X A;  5JI6 A;  1M35 A;  5CNX A;  5E5B A;  2GZ5 A;  2GG9 A;  3MR1 A;  1XNZ A;  3PN9 A;  4U76 A;  3FMQ A;  2BHA A;  4S01 A;  2P9A A;  2BWY A;  2V3X A;  2B3H A;  2GU5 A;  4A6W A;  3BIQ A;  1C22 A;  3PKE A;  1XGM A;  3CB5 A;  2G6P A;  2BHB A;  4RZY A;  1C23 A;  2EVM A;  4ZWP A;  4IDY A;  1KP0 A;  1C27 A;  5E2C A;  4ZNG A;  5CLS A;  1CHM A;  4FO7 A;  5CIK A;  2GA2 A;  4IEC A;  3TAV A;  2V6C A;  2BWX A;  4FLJ A;  1R5G A;  3OVK A;  4HXX A;  1W2M A;  4KM3 A;  1WLR A;  3PKB A;  1QZY A;  1R5H A;  4OOK A;  2ZSG A;  3PKA A;  3PKC A;  2GGC A;  4EGE A;  1A16 A;  2BWV A;  4FLI A;  4IKS A;  4S2T P;  4U6W A;  3TB5 A;  2BWT A;  1MAT A;  1R58 A;  1N51 A;  4S00 A;  2GU7 A;  1YW7 A;  4IPA A;  2EA2 A;  2NQ6 A;  4PNC A;  1WN1 A;  3RVA A;  4U6Z A;  4Z7M A;  2Q93 A;  4MAT A;  3OOO A;  2EVO A;  1XGS A;  3IU9 A;  1QXY A;  4R60 A;  2GG5 A;  1JAW A;  3CB6 A;  1WKM A;  2MAT A;  5FCF A;  4A6V A;  4U71 A;  3PEB A;  2BH3 A;  1BOA A;  3FMR A;  3QOC A;  1C24 A;  2GG3 A;  1XGO A;  2DFI A;  3I7M A;  3IG4 A;  2GG8 A;  3BIT A;  4IKU A;  2EA4 A;  4ZWO A;  3Q6D A;  3IU7 A;  4FKC A;  4IKR A;  2B3K A;  4U73 A;  5D6F A;  2BWS A;  2BWW A;  3O5V A;  1QXW A;  2Q96 A;  3BIP A;  1PV9 A;  1Y1N A;  3L7G A;  2GGB A;  3MX6 A;  2BHC A;  2HOW A;  1YJ3 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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