3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
2BN7A 2GU5A 4IU6A 3PKBA 2EVOA 1M35A 1WL9A 4U71A 1YVMA 3L24A 4U70A 4QR8A 5D6FA 4U75A 3Q6DA 2Q95A 2GTXA 5FCFA 4Z7MA 3CB5A 4IPAA 1CHMA 1XNZA 2NQ6A 3FMQA 4IKSA 1C27A 3IG4A 1WL6A 1WY2A 3RVAA 3IU9A 4U6CA 1QXWA 3S6BA 2GG5A 2BB7A 2GG7A 2B3LA 4FLLA 1C23A 4RGZ1 5CDVA 2ZSGA 1WBQA 1JAWA 4S00A 2GG0A 2Q8KA 5CNXA 2GU7A 1XGMA 3PKAA 2P98A 2BWYA 3D27A 4HXXA 2BWSA 5CE6A 4FLIA 2B3HA 1W2MA 2EVCA 4FO7A 4U6EA 4R60A 3MR1A 1QZYA 1R5GA 5E5BA 4A6VA 4RZZA 4U76A 2OAZA 2EVMA 4U73A 3RORA 2Q94A 4OOKA 3MATA 1Y1NA 2V3XA 1WLRA 2G6PA 5D6EA 1XGSA 1B6AA 4JUQA 1QXYA 1A16A 4FUKA 2BWXA 3BITA 2Q96A 2GG9A 4ZNGA 2BHAA 4IF7A 4FO8A 5JHUA 2Q93A 2P9AA 3CB6A 2ADUA 2GG2A 2BH3A 1C21A 2GGCA 1KP0A 2Q92A 4IECA 2GG3A 4S2TP 1BN5A 1WKMA 4U1BA 2BWUA 3PKDA 4RZYA 3FM3A 2IW2A 4FLJA 4FLKA 3PKCA 1R5HA 1YW8A 3BIQA 3L7GA 4ZWUA 2BHDA 2GG8A 3IU7A 4B28A 2P99A 4PV4A 1XGOA 5CLSA 5CDEA 2V3YA 4U69A 4KM3A 4A6WA 2EA2A 1KQ9A 2GZ5A 5JI6A 2NQ7A 1YW9A 3CTZA 4S2RP 1C24A 2B3KA 2GU4A 2MATA 3BIPA 4U6WA 4EGEA 3FMRA 1BOAA 1WN1A 1KQ0A 4ZWOA 3PKEA 2HOWA 3IU8A 5CDLA 2EA4A 2V6CA 2V3ZA 4PNCA 5JFRA 1W7VA 2GA2A 1N51A 2OKNA 2BWWA 1PV9A 2GU6A 4FKCA 4IKRA 4U6JA 3TB5A 3TAVA 4IDYA 4U6ZA 1YW7A 2GGBA 1C22A 1B59A 5CIKA 4S01A 2BWTA 4IKUA 1QXZA 1MATA 4MATA 4ZWPA 2BWVA 1XGNA 4IKTA 1O0XA 2BHCA 1R58A 2BHBA 5FCHA 1YJ3A 2DFIA 3MX6A
chains in the Genus database with same CATH superfamily
2BN7A 2GU5A 4IU6A 3PKBA 2EVOA 1M35A 1WL9A 4U71A 1YVMA 3L24A 4U70A 4QR8A 5D6FA 4U75A 3Q6DA 2Q95A 2GTXA 5FCFA 4Z7MA 3CB5A 4IPAA 1CHMA 1XNZA 2NQ6A 3FMQA 4IKSA 1C27A 3IG4A 1WL6A 1WY2A 3RVAA 3IU9A 4U6CA 1QXWA 3S6BA 2GG5A 2BB7A 2GG7A 2B3LA 4FLLA 1C23A 4RGZ1 5CDVA 2ZSGA 1WBQA 1JAWA 4S00A 2GG0A 2Q8KA 5CNXA 2GU7A 1XGMA 3PKAA 2P98A 2BWYA 3D27A 4HXXA 2BWSA 5CE6A 4FLIA 2B3HA 1W2MA 2EVCA 4FO7A 4U6EA 4R60A 3MR1A 1QZYA 1R5GA 5E5BA 4A6VA 4RZZA 4U76A 2OAZA 2EVMA 4U73A 3RORA 2Q94A 4OOKA 3MATA 1Y1NA 2V3XA 1WLRA 2G6PA 5D6EA 1XGSA 1B6AA 4JUQA 1QXYA 1A16A 4FUKA 2BWXA 3BITA 2Q96A 2GG9A 4ZNGA 2BHAA 4IF7A 4FO8A 5JHUA 2Q93A 2P9AA 3CB6A 2ADUA 2GG2A 2BH3A 1C21A 2GGCA 1KP0A 2Q92A 4IECA 2GG3A 4S2TP 1BN5A 1WKMA 4U1BA 2BWUA 3PKDA 4RZYA 3FM3A 2IW2A 4FLJA 4FLKA 3PKCA 1R5HA 1YW8A 3BIQA 3L7GA 4ZWUA 2BHDA 2GG8A 3IU7A 4B28A 2P99A 4PV4A 1XGOA 5CLSA 5CDEA 2V3YA 4U69A 4KM3A 4A6WA 2EA2A 1KQ9A 2GZ5A 5JI6A 2NQ7A 1YW9A 3CTZA 4S2RP 1C24A 2B3KA 2GU4A 2MATA 3BIPA 4U6WA 4EGEA 3FMRA 1BOAA 1WN1A 1KQ0A 4ZWOA 3PKEA 2HOWA 3IU8A 5CDLA 2EA4A 2V6CA 2V3ZA 4PNCA 5JFRA 1W7VA 2GA2A 1N51A 2OKNA 2BWWA 1PV9A 2GU6A 4FKCA 4IKRA 4U6JA 3TB5A 3TAVA 4IDYA 4U6ZA 1YW7A 2GGBA 1C22A 1B59A 5CIKA 4S01A 2BWTA 4IKUA 1QXZA 1MATA 4MATA 4ZWPA 2BWVA 1XGNA 4IKTA 1O0XA 2BHCA 1R58A 2BHBA 5FCHA 1YJ3A 2DFIA 3MX6A
chains in the Genus database with same CATH topology
2BN7A 2GU5A 4IU6A 3PKBA 2EVOA 1M35A 1WL9A 4U71A 1YVMA 3L24A 4U70A 4QR8A 5D6FA 4U75A 3Q6DA 2Q95A 2GTXA 5FCFA 4Z7MA 3CB5A 4IPAA 1CHMA 1XNZA 2NQ6A 3FMQA 4IKSA 1C27A 3IG4A 1WL6A 1WY2A 3RVAA 3IU9A 4U6CA 1QXWA 3S6BA 2GG5A 2BB7A 2GG7A 2B3LA 4FLLA 1C23A 4RGZ1 5CDVA 2ZSGA 1WBQA 1JAWA 4S00A 2GG0A 2Q8KA 5CNXA 2GU7A 1XGMA 3PKAA 2P98A 2BWYA 3D27A 4HXXA 2BWSA 5CE6A 4FLIA 2B3HA 1W2MA 2EVCA 4FO7A 4U6EA 4R60A 3MR1A 1QZYA 1R5GA 5E5BA 4A6VA 4RZZA 4U76A 2OAZA 2EVMA 4U73A 3RORA 2Q94A 4OOKA 3MATA 1Y1NA 2V3XA 1WLRA 2G6PA 5D6EA 1XGSA 1B6AA 4JUQA 1QXYA 1A16A 4FUKA 2BWXA 3BITA 2Q96A 2GG9A 4ZNGA 2BHAA 4IF7A 4FO8A 5JHUA 2Q93A 2P9AA 3CB6A 2ADUA 2GG2A 2BH3A 1C21A 2GGCA 1KP0A 2Q92A 4IECA 2GG3A 4S2TP 1BN5A 1WKMA 4U1BA 2BWUA 3PKDA 4RZYA 3FM3A 2IW2A 4FLJA 4FLKA 3PKCA 1R5HA 1YW8A 3BIQA 3L7GA 4ZWUA 2BHDA 2GG8A 3IU7A 4B28A 2P99A 4PV4A 1XGOA 5CLSA 5CDEA 2V3YA 4U69A 4KM3A 4A6WA 2EA2A 1KQ9A 2GZ5A 5JI6A 2NQ7A 1YW9A 3CTZA 4S2RP 1C24A 2B3KA 2GU4A 2MATA 3BIPA 4U6WA 4EGEA 3FMRA 1BOAA 1WN1A 1KQ0A 4ZWOA 3PKEA 2HOWA 3IU8A 5CDLA 2EA4A 2V6CA 2V3ZA 4PNCA 5JFRA 1W7VA 2GA2A 1N51A 2OKNA 2BWWA 1PV9A 2GU6A 4FKCA 4IKRA 4U6JA 3TB5A 3TAVA 4IDYA 4U6ZA 1YW7A 2GGBA 1C22A 1B59A 5CIKA 4S01A 2BWTA 4IKUA 1QXZA 1MATA 4MATA 4ZWPA 2BWVA 1XGNA 4IKTA 1O0XA 2BHCA 1R58A 2BHBA 5FCHA 1YJ3A 2DFIA 3MX6A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2BN7 A;  2GU5 A;  4IU6 A;  3PKB A;  2EVO A;  1M35 A;  1WL9 A;  4U71 A;  1YVM A;  3L24 A;  4U70 A;  4QR8 A;  5D6F A;  4U75 A;  3Q6D A;  2Q95 A;  2GTX A;  5FCF A;  4Z7M A;  3CB5 A;  4IPA A;  1CHM A;  1XNZ A;  2NQ6 A;  3FMQ A;  4IKS A;  1C27 A;  3IG4 A;  1WL6 A;  1WY2 A;  3RVA A;  3IU9 A;  4U6C A;  1QXW A;  3S6B A;  2GG5 A;  2BB7 A;  2GG7 A;  2B3L A;  4FLL A;  1C23 A;  4RGZ 1;  5CDV A;  2ZSG A;  1WBQ A;  1JAW A;  4S00 A;  2GG0 A;  2Q8K A;  5CNX A;  2GU7 A;  1XGM A;  3PKA A;  2P98 A;  2BWY A;  3D27 A;  4HXX A;  2BWS A;  5CE6 A;  4FLI A;  2B3H A;  1W2M A;  2EVC A;  4FO7 A;  4U6E A;  4R60 A;  3MR1 A;  1QZY A;  1R5G A;  5E5B A;  4A6V A;  4RZZ A;  4U76 A;  2OAZ A;  2EVM A;  4U73 A;  3ROR A;  2Q94 A;  4OOK A;  3MAT A;  1Y1N A;  2V3X A;  1WLR A;  2G6P A;  5D6E A;  1XGS A;  1B6A A;  4JUQ A;  1QXY A;  1A16 A;  4FUK A;  2BWX A;  3BIT A;  2Q96 A;  2GG9 A;  4ZNG A;  2BHA A;  4IF7 A;  4FO8 A;  5JHU A;  2Q93 A;  2P9A A;  3CB6 A;  2ADU A;  2GG2 A;  2BH3 A;  1C21 A;  2GGC A;  1KP0 A;  2Q92 A;  4IEC A;  2GG3 A;  4S2T P;  1BN5 A;  1WKM A;  4U1B A;  2BWU A;  3PKD A;  4RZY A;  3FM3 A;  2IW2 A;  4FLJ A;  4FLK A;  3PKC A;  1R5H A;  1YW8 A;  3BIQ A;  3L7G A;  4ZWU A;  2BHD A;  2GG8 A;  3IU7 A;  4B28 A;  2P99 A;  4PV4 A;  1XGO A;  5CLS A;  5CDE A;  2V3Y A;  4U69 A;  4KM3 A;  4A6W A;  2EA2 A;  1KQ9 A;  2GZ5 A;  5JI6 A;  2NQ7 A;  1YW9 A;  3CTZ A;  4S2R P;  1C24 A;  2B3K A;  2GU4 A;  2MAT A;  3BIP A;  4U6W A;  4EGE A;  3FMR A;  1BOA A;  1WN1 A;  1KQ0 A;  4ZWO A;  3PKE A;  2HOW A;  3IU8 A;  5CDL A;  2EA4 A;  2V6C A;  2V3Z A;  4PNC A;  5JFR A;  1W7V A;  2GA2 A;  1N51 A;  2OKN A;  2BWW A;  1PV9 A;  2GU6 A;  4FKC A;  4IKR A;  4U6J A;  3TB5 A;  3TAV A;  4IDY A;  4U6Z A;  1YW7 A;  2GGB A;  1C22 A;  1B59 A;  5CIK A;  4S01 A;  2BWT A;  4IKU A;  1QXZ A;  1MAT A;  4MAT A;  4ZWP A;  2BWV A;  1XGN A;  4IKT A;  1O0X A;  2BHC A;  1R58 A;  2BHB A;  5FCH A;  1YJ3 A;  2DFI A;  3MX6 A; 
#chains in the Genus database with same CATH topology
 2BN7 A;  2GU5 A;  4IU6 A;  3PKB A;  2EVO A;  1M35 A;  1WL9 A;  4U71 A;  1YVM A;  3L24 A;  4U70 A;  4QR8 A;  5D6F A;  4U75 A;  3Q6D A;  2Q95 A;  2GTX A;  5FCF A;  4Z7M A;  3CB5 A;  4IPA A;  1CHM A;  1XNZ A;  2NQ6 A;  3FMQ A;  4IKS A;  1C27 A;  3IG4 A;  1WL6 A;  1WY2 A;  3RVA A;  3IU9 A;  4U6C A;  1QXW A;  3S6B A;  2GG5 A;  2BB7 A;  2GG7 A;  2B3L A;  4FLL A;  1C23 A;  4RGZ 1;  5CDV A;  2ZSG A;  1WBQ A;  1JAW A;  4S00 A;  2GG0 A;  2Q8K A;  5CNX A;  2GU7 A;  1XGM A;  3PKA A;  2P98 A;  2BWY A;  3D27 A;  4HXX A;  2BWS A;  5CE6 A;  4FLI A;  2B3H A;  1W2M A;  2EVC A;  4FO7 A;  4U6E A;  4R60 A;  3MR1 A;  1QZY A;  1R5G A;  5E5B A;  4A6V A;  4RZZ A;  4U76 A;  2OAZ A;  2EVM A;  4U73 A;  3ROR A;  2Q94 A;  4OOK A;  3MAT A;  1Y1N A;  2V3X A;  1WLR A;  2G6P A;  5D6E A;  1XGS A;  1B6A A;  4JUQ A;  1QXY A;  1A16 A;  4FUK A;  2BWX A;  3BIT A;  2Q96 A;  2GG9 A;  4ZNG A;  2BHA A;  4IF7 A;  4FO8 A;  5JHU A;  2Q93 A;  2P9A A;  3CB6 A;  2ADU A;  2GG2 A;  2BH3 A;  1C21 A;  2GGC A;  1KP0 A;  2Q92 A;  4IEC A;  2GG3 A;  4S2T P;  1BN5 A;  1WKM A;  4U1B A;  2BWU A;  3PKD A;  4RZY A;  3FM3 A;  2IW2 A;  4FLJ A;  4FLK A;  3PKC A;  1R5H A;  1YW8 A;  3BIQ A;  3L7G A;  4ZWU A;  2BHD A;  2GG8 A;  3IU7 A;  4B28 A;  2P99 A;  4PV4 A;  1XGO A;  5CLS A;  5CDE A;  2V3Y A;  4U69 A;  4KM3 A;  4A6W A;  2EA2 A;  1KQ9 A;  2GZ5 A;  5JI6 A;  2NQ7 A;  1YW9 A;  3CTZ A;  4S2R P;  1C24 A;  2B3K A;  2GU4 A;  2MAT A;  3BIP A;  4U6W A;  4EGE A;  3FMR A;  1BOA A;  1WN1 A;  1KQ0 A;  4ZWO A;  3PKE A;  2HOW A;  3IU8 A;  5CDL A;  2EA4 A;  2V6C A;  2V3Z A;  4PNC A;  5JFR A;  1W7V A;  2GA2 A;  1N51 A;  2OKN A;  2BWW A;  1PV9 A;  2GU6 A;  4FKC A;  4IKR A;  4U6J A;  3TB5 A;  3TAV A;  4IDY A;  4U6Z A;  1YW7 A;  2GGB A;  1C22 A;  1B59 A;  5CIK A;  4S01 A;  2BWT A;  4IKU A;  1QXZ A;  1MAT A;  4MAT A;  4ZWP A;  2BWV A;  1XGN A;  4IKT A;  1O0X A;  2BHC A;  1R58 A;  2BHB A;  5FCH A;  1YJ3 A;  2DFI A;  3MX6 A; 
#chains in the Genus database with same CATH homology
 2BN7 A;  2GU5 A;  4IU6 A;  3PKB A;  2EVO A;  1M35 A;  1WL9 A;  4U71 A;  1YVM A;  3L24 A;  4U70 A;  4QR8 A;  5D6F A;  4U75 A;  3Q6D A;  2Q95 A;  2GTX A;  5FCF A;  4Z7M A;  3CB5 A;  4IPA A;  1CHM A;  1XNZ A;  2NQ6 A;  3FMQ A;  4IKS A;  1C27 A;  3IG4 A;  1WL6 A;  1WY2 A;  3RVA A;  3IU9 A;  4U6C A;  1QXW A;  3S6B A;  2GG5 A;  2BB7 A;  2GG7 A;  2B3L A;  4FLL A;  1C23 A;  4RGZ 1;  5CDV A;  2ZSG A;  1WBQ A;  1JAW A;  4S00 A;  2GG0 A;  2Q8K A;  5CNX A;  2GU7 A;  1XGM A;  3PKA A;  2P98 A;  2BWY A;  3D27 A;  4HXX A;  2BWS A;  5CE6 A;  4FLI A;  2B3H A;  1W2M A;  2EVC A;  4FO7 A;  4U6E A;  4R60 A;  3MR1 A;  1QZY A;  1R5G A;  5E5B A;  4A6V A;  4RZZ A;  4U76 A;  2OAZ A;  2EVM A;  4U73 A;  3ROR A;  2Q94 A;  4OOK A;  3MAT A;  1Y1N A;  2V3X A;  1WLR A;  2G6P A;  5D6E A;  1XGS A;  1B6A A;  4JUQ A;  1QXY A;  1A16 A;  4FUK A;  2BWX A;  3BIT A;  2Q96 A;  2GG9 A;  4ZNG A;  2BHA A;  4IF7 A;  4FO8 A;  5JHU A;  2Q93 A;  2P9A A;  3CB6 A;  2ADU A;  2GG2 A;  2BH3 A;  1C21 A;  2GGC A;  1KP0 A;  2Q92 A;  4IEC A;  2GG3 A;  4S2T P;  1BN5 A;  1WKM A;  4U1B A;  2BWU A;  3PKD A;  4RZY A;  3FM3 A;  2IW2 A;  4FLJ A;  4FLK A;  3PKC A;  1R5H A;  1YW8 A;  3BIQ A;  3L7G A;  4ZWU A;  2BHD A;  2GG8 A;  3IU7 A;  4B28 A;  2P99 A;  4PV4 A;  1XGO A;  5CLS A;  5CDE A;  2V3Y A;  4U69 A;  4KM3 A;  4A6W A;  2EA2 A;  1KQ9 A;  2GZ5 A;  5JI6 A;  2NQ7 A;  1YW9 A;  3CTZ A;  4S2R P;  1C24 A;  2B3K A;  2GU4 A;  2MAT A;  3BIP A;  4U6W A;  4EGE A;  3FMR A;  1BOA A;  1WN1 A;  1KQ0 A;  4ZWO A;  3PKE A;  2HOW A;  3IU8 A;  5CDL A;  2EA4 A;  2V6C A;  2V3Z A;  4PNC A;  5JFR A;  1W7V A;  2GA2 A;  1N51 A;  2OKN A;  2BWW A;  1PV9 A;  2GU6 A;  4FKC A;  4IKR A;  4U6J A;  3TB5 A;  3TAV A;  4IDY A;  4U6Z A;  1YW7 A;  2GGB A;  1C22 A;  1B59 A;  5CIK A;  4S01 A;  2BWT A;  4IKU A;  1QXZ A;  1MAT A;  4MAT A;  4ZWP A;  2BWV A;  1XGN A;  4IKT A;  1O0X A;  2BHC A;  1R58 A;  2BHB A;  5FCH A;  1YJ3 A;  2DFI A;  3MX6 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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