2ZSGA

Crystal structure of x-pro aminopeptidase from thermotoga maritima msb8
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
359
structure length
356
Chain Sequence
MDRSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVDFIDVLKKTVNDLKIKTIALEEERVSLSLFRRISSAFGDRKFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIGLEVHEGPAISFRNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILTTLPRSIFVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of X-Pro aminopeptidase from Thermotoga maritima MSB8
rcsb
molecule tags Hydrolase
source organism Thermotoga maritima
molecule keywords Aminopeptidase P, putative
total genus 124
structure length 356
sequence length 359
chains with identical sequence B
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2zsgA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2zsgA02
2B3LA 4FUKA 3L7GA 2GG3A 1PV9A 4R60A 4FKCA 2HOWA 3QOCA 2P9AA 4FLIA 3D27A 4U73A 2NQ7A 3BIPA 1KQ0A 4U6EA 2GTXA 4U76A 2BWXA 2BWSA 4ZNGA 1C24A 2IW2A 3IU9A 5D6FA 4ZWPA 4RGZ1 4S01A 1YJ3A 2EA2A 2G6PA 4U75A 2GG7A 1XGSA 5CE6A 4FO7A 1C22A 3IU7A 1R58A 2OKNA 3TB5A 4U69A 3I7MA 1B59A 4IPAA 1CHMA 1WLRA 4U6WA 1KP0A 1M35A 2EVCA 1XGNA 2ZSGA 2GA2A 1A16A 1YW7A 2GG2A 2BWVA 3PKCA 4U6ZA 4JUQA 3PN9A 2BHCA 1QXYA 2Q92A 3IG4A 4ZWUA 4EGEA 4QR8A 4S2TP 1BN5A 4S2RP 1WN1A 5CDEA 5JFRA 4RZZA 2Q96A 4IKSA 1MATA 1O0XA 2B3KA 1YVMA 4PNCA 2NQ6A 1JAWA 4RZYA 2V6CA 5E5BA 2Q95A 4B28A 3PKDA 1C27A 3L24A 2DFIA 1XGMA 3MX6A 2MATA 4HXXA 4ZWOA 2EA4A 2P98A 2GU6A 2BWYA 2V3XA 3FM3A 3MATA 5CNXA 2EVMA 1QXWA 3PKBA 3Q6DA 5JHUA 4IU6A 1KQ9A 2GGBA 4FLJA 4U6CA 1R5GA 2GU5A 4U6JA 5CDVA 3BITA 3CB6A 2BWTA 1BOAA 2BN7A 2V3YA 3BIQA 1WBQA 5CIKA 2GGCA 3FMQA 1XNZA 4S00A 4Z7MA 4IKTA 5CLSA 2ADUA 1C21A 3IL0A 2EVOA 2P99A 1WL6A 1R5HA 1W7VA 4MATA 3PKEA 2V3ZA 2GG0A 4U1BA 5FCHA 1YW8A 1Y1NA 2BB7A 4FO8A 4U70A 5CDLA 2B3HA 3OVKA 2BWUA 3IU8A 3MR1A 2GG5A 4IECA 3FMRA 1C23A 4PV4A 2GG8A 2GZ5A 1YW9A 3CB5A 2GG9A 4IDYA 4OOKA 2BWWA 2OAZA 1WKMA 5FCFA 3S6BA 1W2MA 2BHBA 3TAVA 2BH3A 5JI6A 3RORA 1QZYA 4FLKA 3O5VA 4U71A 3RVAA 1N51A 3PKAA 3CTZA 4A6WA 3PEBA 3OOOA 4IKRA 2Q8KA 1WY2A 5D6EA 2GU7A 2Q94A 2GU4A 2BHDA 4A6VA 4KM3A 1B6AA 2BHAA 1QXZA 1XGOA 4IKUA 4FLLA 4IF7A 5E2CA 1WL9A 2Q93A
chains in the Genus database with same CATH superfamily
2B3LA 4FUKA 3L7GA 2GG3A 1PV9A 4R60A 4FKCA 2HOWA 3QOCA 2P9AA 4FLIA 3D27A 4U73A 2NQ7A 3BIPA 1KQ0A 4U6EA 2GTXA 4U76A 2BWXA 2BWSA 4ZNGA 1C24A 2IW2A 3IU9A 5D6FA 4ZWPA 4RGZ1 4S01A 1YJ3A 2EA2A 2G6PA 4U75A 2GG7A 1XGSA 5CE6A 4FO7A 1C22A 3IU7A 1R58A 2OKNA 3TB5A 4U69A 3I7MA 1B59A 4IPAA 1CHMA 1WLRA 4U6WA 1KP0A 1M35A 2EVCA 1XGNA 2ZSGA 2GA2A 1A16A 1YW7A 2GG2A 2BWVA 3PKCA 4U6ZA 4JUQA 3PN9A 2BHCA 1QXYA 2Q92A 3IG4A 4ZWUA 4EGEA 4QR8A 4S2TP 1BN5A 4S2RP 1WN1A 5CDEA 5JFRA 4RZZA 2Q96A 4IKSA 1MATA 1O0XA 2B3KA 1YVMA 4PNCA 2NQ6A 1JAWA 4RZYA 2V6CA 5E5BA 2Q95A 4B28A 3PKDA 1C27A 3L24A 2DFIA 1XGMA 3MX6A 2MATA 4HXXA 4ZWOA 2EA4A 2P98A 2GU6A 2BWYA 2V3XA 3FM3A 3MATA 5CNXA 2EVMA 1QXWA 3PKBA 3Q6DA 5JHUA 4IU6A 1KQ9A 2GGBA 4FLJA 4U6CA 1R5GA 2GU5A 4U6JA 5CDVA 3BITA 3CB6A 2BWTA 1BOAA 2BN7A 2V3YA 3BIQA 1WBQA 5CIKA 2GGCA 3FMQA 1XNZA 4S00A 4Z7MA 4IKTA 5CLSA 2ADUA 1C21A 3IL0A 2EVOA 2P99A 1WL6A 1R5HA 1W7VA 4MATA 3PKEA 2V3ZA 2GG0A 4U1BA 5FCHA 1YW8A 1Y1NA 2BB7A 4FO8A 4U70A 5CDLA 2B3HA 3OVKA 2BWUA 3IU8A 3MR1A 2GG5A 4IECA 3FMRA 1C23A 4PV4A 2GG8A 2GZ5A 1YW9A 3CB5A 2GG9A 4IDYA 4OOKA 2BWWA 2OAZA 1WKMA 5FCFA 3S6BA 1W2MA 2BHBA 3TAVA 2BH3A 5JI6A 3RORA 1QZYA 4FLKA 3O5VA 4U71A 3RVAA 1N51A 3PKAA 3CTZA 4A6WA 3PEBA 3OOOA 4IKRA 2Q8KA 1WY2A 5D6EA 2GU7A 2Q94A 2GU4A 2BHDA 4A6VA 4KM3A 1B6AA 2BHAA 1QXZA 1XGOA 4IKUA 4FLLA 4IF7A 5E2CA 1WL9A 2Q93A
chains in the Genus database with same CATH topology
2B3LA 4FUKA 3L7GA 2GG3A 1PV9A 4R60A 4FKCA 2HOWA 3QOCA 2P9AA 4FLIA 3D27A 4U73A 2NQ7A 3BIPA 1KQ0A 4U6EA 2GTXA 4U76A 2BWXA 2BWSA 4ZNGA 1C24A 2IW2A 3IU9A 5D6FA 4ZWPA 4RGZ1 4S01A 1YJ3A 2EA2A 2G6PA 4U75A 2GG7A 1XGSA 5CE6A 4FO7A 1C22A 3IU7A 1R58A 2OKNA 3TB5A 4U69A 3I7MA 1B59A 4IPAA 1CHMA 1WLRA 4U6WA 1KP0A 1M35A 2EVCA 1XGNA 2ZSGA 2GA2A 1A16A 1YW7A 2GG2A 2BWVA 3PKCA 4U6ZA 4JUQA 3PN9A 2BHCA 1QXYA 2Q92A 3IG4A 4ZWUA 4EGEA 4QR8A 4S2TP 1BN5A 4S2RP 1WN1A 5CDEA 5JFRA 4RZZA 2Q96A 4IKSA 1MATA 1O0XA 2B3KA 1YVMA 4PNCA 2NQ6A 1JAWA 4RZYA 2V6CA 5E5BA 2Q95A 4B28A 3PKDA 1C27A 3L24A 2DFIA 1XGMA 3MX6A 2MATA 4HXXA 4ZWOA 2EA4A 2P98A 2GU6A 2BWYA 2V3XA 3FM3A 3MATA 5CNXA 2EVMA 1QXWA 3PKBA 3Q6DA 5JHUA 4IU6A 1KQ9A 2GGBA 4FLJA 4U6CA 1R5GA 2GU5A 4U6JA 5CDVA 3BITA 3CB6A 2BWTA 1BOAA 2BN7A 2V3YA 3BIQA 1WBQA 5CIKA 2GGCA 3FMQA 1XNZA 4S00A 4Z7MA 4IKTA 5CLSA 2ADUA 1C21A 3IL0A 2EVOA 2P99A 1WL6A 1R5HA 1W7VA 4MATA 3PKEA 2V3ZA 2GG0A 4U1BA 5FCHA 1YW8A 1Y1NA 2BB7A 4FO8A 4U70A 5CDLA 2B3HA 3OVKA 2BWUA 3IU8A 3MR1A 2GG5A 4IECA 3FMRA 1C23A 4PV4A 2GG8A 2GZ5A 1YW9A 3CB5A 2GG9A 4IDYA 4OOKA 2BWWA 2OAZA 1WKMA 5FCFA 3S6BA 1W2MA 2BHBA 3TAVA 2BH3A 5JI6A 3RORA 1QZYA 4FLKA 3O5VA 4U71A 3RVAA 1N51A 3PKAA 3CTZA 4A6WA 3PEBA 3OOOA 4IKRA 2Q8KA 1WY2A 5D6EA 2GU7A 2Q94A 2GU4A 2BHDA 4A6VA 4KM3A 1B6AA 2BHAA 1QXZA 1XGOA 4IKUA 4FLLA 4IF7A 5E2CA 1WL9A 2Q93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B3L A;  4FUK A;  3L7G A;  2GG3 A;  1PV9 A;  4R60 A;  4FKC A;  2HOW A;  3QOC A;  2P9A A;  4FLI A;  3D27 A;  4U73 A;  2NQ7 A;  3BIP A;  1KQ0 A;  4U6E A;  2GTX A;  4U76 A;  2BWX A;  2BWS A;  4ZNG A;  1C24 A;  2IW2 A;  3IU9 A;  5D6F A;  4ZWP A;  4RGZ 1;  4S01 A;  1YJ3 A;  2EA2 A;  2G6P A;  4U75 A;  2GG7 A;  1XGS A;  5CE6 A;  4FO7 A;  1C22 A;  3IU7 A;  1R58 A;  2OKN A;  3TB5 A;  4U69 A;  3I7M A;  1B59 A;  4IPA A;  1CHM A;  1WLR A;  4U6W A;  1KP0 A;  1M35 A;  2EVC A;  1XGN A;  2ZSG A;  2GA2 A;  1A16 A;  1YW7 A;  2GG2 A;  2BWV A;  3PKC A;  4U6Z A;  4JUQ A;  3PN9 A;  2BHC A;  1QXY A;  2Q92 A;  3IG4 A;  4ZWU A;  4EGE A;  4QR8 A;  4S2T P;  1BN5 A;  4S2R P;  1WN1 A;  5CDE A;  5JFR A;  4RZZ A;  2Q96 A;  4IKS A;  1MAT A;  1O0X A;  2B3K A;  1YVM A;  4PNC A;  2NQ6 A;  1JAW A;  4RZY A;  2V6C A;  5E5B A;  2Q95 A;  4B28 A;  3PKD A;  1C27 A;  3L24 A;  2DFI A;  1XGM A;  3MX6 A;  2MAT A;  4HXX A;  4ZWO A;  2EA4 A;  2P98 A;  2GU6 A;  2BWY A;  2V3X A;  3FM3 A;  3MAT A;  5CNX A;  2EVM A;  1QXW A;  3PKB A;  3Q6D A;  5JHU A;  4IU6 A;  1KQ9 A;  2GGB A;  4FLJ A;  4U6C A;  1R5G A;  2GU5 A;  4U6J A;  5CDV A;  3BIT A;  3CB6 A;  2BWT A;  1BOA A;  2BN7 A;  2V3Y A;  3BIQ A;  1WBQ A;  5CIK A;  2GGC A;  3FMQ A;  1XNZ A;  4S00 A;  4Z7M A;  4IKT A;  5CLS A;  2ADU A;  1C21 A;  3IL0 A;  2EVO A;  2P99 A;  1WL6 A;  1R5H A;  1W7V A;  4MAT A;  3PKE A;  2V3Z A;  2GG0 A;  4U1B A;  5FCH A;  1YW8 A;  1Y1N A;  2BB7 A;  4FO8 A;  4U70 A;  5CDL A;  2B3H A;  3OVK A;  2BWU A;  3IU8 A;  3MR1 A;  2GG5 A;  4IEC A;  3FMR A;  1C23 A;  4PV4 A;  2GG8 A;  2GZ5 A;  1YW9 A;  3CB5 A;  2GG9 A;  4IDY A;  4OOK A;  2BWW A;  2OAZ A;  1WKM A;  5FCF A;  3S6B A;  1W2M A;  2BHB A;  3TAV A;  2BH3 A;  5JI6 A;  3ROR A;  1QZY A;  4FLK A;  3O5V A;  4U71 A;  3RVA A;  1N51 A;  3PKA A;  3CTZ A;  4A6W A;  3PEB A;  3OOO A;  4IKR A;  2Q8K A;  1WY2 A;  5D6E A;  2GU7 A;  2Q94 A;  2GU4 A;  2BHD A;  4A6V A;  4KM3 A;  1B6A A;  2BHA A;  1QXZ A;  1XGO A;  4IKU A;  4FLL A;  4IF7 A;  5E2C A;  1WL9 A;  2Q93 A; 
#chains in the Genus database with same CATH topology
 2B3L A;  4FUK A;  3L7G A;  2GG3 A;  1PV9 A;  4R60 A;  4FKC A;  2HOW A;  3QOC A;  2P9A A;  4FLI A;  3D27 A;  4U73 A;  2NQ7 A;  3BIP A;  1KQ0 A;  4U6E A;  2GTX A;  4U76 A;  2BWX A;  2BWS A;  4ZNG A;  1C24 A;  2IW2 A;  3IU9 A;  5D6F A;  4ZWP A;  4RGZ 1;  4S01 A;  1YJ3 A;  2EA2 A;  2G6P A;  4U75 A;  2GG7 A;  1XGS A;  5CE6 A;  4FO7 A;  1C22 A;  3IU7 A;  1R58 A;  2OKN A;  3TB5 A;  4U69 A;  3I7M A;  1B59 A;  4IPA A;  1CHM A;  1WLR A;  4U6W A;  1KP0 A;  1M35 A;  2EVC A;  1XGN A;  2ZSG A;  2GA2 A;  1A16 A;  1YW7 A;  2GG2 A;  2BWV A;  3PKC A;  4U6Z A;  4JUQ A;  3PN9 A;  2BHC A;  1QXY A;  2Q92 A;  3IG4 A;  4ZWU A;  4EGE A;  4QR8 A;  4S2T P;  1BN5 A;  4S2R P;  1WN1 A;  5CDE A;  5JFR A;  4RZZ A;  2Q96 A;  4IKS A;  1MAT A;  1O0X A;  2B3K A;  1YVM A;  4PNC A;  2NQ6 A;  1JAW A;  4RZY A;  2V6C A;  5E5B A;  2Q95 A;  4B28 A;  3PKD A;  1C27 A;  3L24 A;  2DFI A;  1XGM A;  3MX6 A;  2MAT A;  4HXX A;  4ZWO A;  2EA4 A;  2P98 A;  2GU6 A;  2BWY A;  2V3X A;  3FM3 A;  3MAT A;  5CNX A;  2EVM A;  1QXW A;  3PKB A;  3Q6D A;  5JHU A;  4IU6 A;  1KQ9 A;  2GGB A;  4FLJ A;  4U6C A;  1R5G A;  2GU5 A;  4U6J A;  5CDV A;  3BIT A;  3CB6 A;  2BWT A;  1BOA A;  2BN7 A;  2V3Y A;  3BIQ A;  1WBQ A;  5CIK A;  2GGC A;  3FMQ A;  1XNZ A;  4S00 A;  4Z7M A;  4IKT A;  5CLS A;  2ADU A;  1C21 A;  3IL0 A;  2EVO A;  2P99 A;  1WL6 A;  1R5H A;  1W7V A;  4MAT A;  3PKE A;  2V3Z A;  2GG0 A;  4U1B A;  5FCH A;  1YW8 A;  1Y1N A;  2BB7 A;  4FO8 A;  4U70 A;  5CDL A;  2B3H A;  3OVK A;  2BWU A;  3IU8 A;  3MR1 A;  2GG5 A;  4IEC A;  3FMR A;  1C23 A;  4PV4 A;  2GG8 A;  2GZ5 A;  1YW9 A;  3CB5 A;  2GG9 A;  4IDY A;  4OOK A;  2BWW A;  2OAZ A;  1WKM A;  5FCF A;  3S6B A;  1W2M A;  2BHB A;  3TAV A;  2BH3 A;  5JI6 A;  3ROR A;  1QZY A;  4FLK A;  3O5V A;  4U71 A;  3RVA A;  1N51 A;  3PKA A;  3CTZ A;  4A6W A;  3PEB A;  3OOO A;  4IKR A;  2Q8K A;  1WY2 A;  5D6E A;  2GU7 A;  2Q94 A;  2GU4 A;  2BHD A;  4A6V A;  4KM3 A;  1B6A A;  2BHA A;  1QXZ A;  1XGO A;  4IKU A;  4FLL A;  4IF7 A;  5E2C A;  1WL9 A;  2Q93 A; 
#chains in the Genus database with same CATH homology
 2B3L A;  4FUK A;  3L7G A;  2GG3 A;  1PV9 A;  4R60 A;  4FKC A;  2HOW A;  3QOC A;  2P9A A;  4FLI A;  3D27 A;  4U73 A;  2NQ7 A;  3BIP A;  1KQ0 A;  4U6E A;  2GTX A;  4U76 A;  2BWX A;  2BWS A;  4ZNG A;  1C24 A;  2IW2 A;  3IU9 A;  5D6F A;  4ZWP A;  4RGZ 1;  4S01 A;  1YJ3 A;  2EA2 A;  2G6P A;  4U75 A;  2GG7 A;  1XGS A;  5CE6 A;  4FO7 A;  1C22 A;  3IU7 A;  1R58 A;  2OKN A;  3TB5 A;  4U69 A;  3I7M A;  1B59 A;  4IPA A;  1CHM A;  1WLR A;  4U6W A;  1KP0 A;  1M35 A;  2EVC A;  1XGN A;  2ZSG A;  2GA2 A;  1A16 A;  1YW7 A;  2GG2 A;  2BWV A;  3PKC A;  4U6Z A;  4JUQ A;  3PN9 A;  2BHC A;  1QXY A;  2Q92 A;  3IG4 A;  4ZWU A;  4EGE A;  4QR8 A;  4S2T P;  1BN5 A;  4S2R P;  1WN1 A;  5CDE A;  5JFR A;  4RZZ A;  2Q96 A;  4IKS A;  1MAT A;  1O0X A;  2B3K A;  1YVM A;  4PNC A;  2NQ6 A;  1JAW A;  4RZY A;  2V6C A;  5E5B A;  2Q95 A;  4B28 A;  3PKD A;  1C27 A;  3L24 A;  2DFI A;  1XGM A;  3MX6 A;  2MAT A;  4HXX A;  4ZWO A;  2EA4 A;  2P98 A;  2GU6 A;  2BWY A;  2V3X A;  3FM3 A;  3MAT A;  5CNX A;  2EVM A;  1QXW A;  3PKB A;  3Q6D A;  5JHU A;  4IU6 A;  1KQ9 A;  2GGB A;  4FLJ A;  4U6C A;  1R5G A;  2GU5 A;  4U6J A;  5CDV A;  3BIT A;  3CB6 A;  2BWT A;  1BOA A;  2BN7 A;  2V3Y A;  3BIQ A;  1WBQ A;  5CIK A;  2GGC A;  3FMQ A;  1XNZ A;  4S00 A;  4Z7M A;  4IKT A;  5CLS A;  2ADU A;  1C21 A;  3IL0 A;  2EVO A;  2P99 A;  1WL6 A;  1R5H A;  1W7V A;  4MAT A;  3PKE A;  2V3Z A;  2GG0 A;  4U1B A;  5FCH A;  1YW8 A;  1Y1N A;  2BB7 A;  4FO8 A;  4U70 A;  5CDL A;  2B3H A;  3OVK A;  2BWU A;  3IU8 A;  3MR1 A;  2GG5 A;  4IEC A;  3FMR A;  1C23 A;  4PV4 A;  2GG8 A;  2GZ5 A;  1YW9 A;  3CB5 A;  2GG9 A;  4IDY A;  4OOK A;  2BWW A;  2OAZ A;  1WKM A;  5FCF A;  3S6B A;  1W2M A;  2BHB A;  3TAV A;  2BH3 A;  5JI6 A;  3ROR A;  1QZY A;  4FLK A;  3O5V A;  4U71 A;  3RVA A;  1N51 A;  3PKA A;  3CTZ A;  4A6W A;  3PEB A;  3OOO A;  4IKR A;  2Q8K A;  1WY2 A;  5D6E A;  2GU7 A;  2Q94 A;  2GU4 A;  2BHD A;  4A6V A;  4KM3 A;  1B6A A;  2BHA A;  1QXZ A;  1XGO A;  4IKU A;  4FLL A;  4IF7 A;  5E2C A;  1WL9 A;  2Q93 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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