3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
1C27A 2BB7A 2BWSA 2BN7A 2B3LA 3CB5A 2EVOA 4IKRA 2B3HA 1KQ9A 3RORA 2P98A 4RZZA 2EA2A 4JUQA 4QR8A 1R5HA 1C24A 2OAZA 5CDLA 2BHCA 1R5GA 2GZ5A 2GU6A 4U69A 2GG2A 2Q93A 4MATA 1KP0A 2BH3A 2Q8KA 2V6CA 3PKCA 4FKCA 4FO8A 2GG5A 2GG8A 4PNCA 2Q94A 3IU9A 2BHBA 2V3XA 5CNXA 2V3ZA 4R60A 5D6FA 1CHMA 1MATA 4U6WA 3IG4A 3TAVA 3IU8A 3PKBA 1QXYA 2BWYA 2EA4A 1B59A 2GTXA 4U70A 3CTZA 1Y1NA 2GG0A 1WY2A 2MATA 1M35A 3BIPA 2GG3A 2GG7A 2DFIA 2ADUA 5JFRA 4ZWPA 1C22A 2GGCA 5FCHA 1WLRA 1O0XA 2HOWA 4RGZ1 1C23A 3FMQA 4IPAA 3FMRA 2EVCA 1YW9A 4U73A 4HXXA 4U1BA 1WKMA 4FUKA 5CLSA 2GG9A 1BN5A 1XNZA 4FLIA 1WBQA 4IKUA 2V3YA 4IDYA 4B28A 1R58A 4U75A 3TB5A 4S2RP 4FLKA 4U6JA 4A6VA 2GU7A 2BHDA 1XGMA 1XGNA 4U76A 2Q92A 2GU5A 3PKEA 4RZYA 4ZWUA 2B3KA 2BWVA 4S01A 1W2MA 2ZSGA 1JAWA 4ZNGA 2Q96A 1C21A 2GGBA 4U71A 2BWXA 1N51A 1XGSA 3MATA 5CDVA 4IU6A 1QXWA 3Q6DA 4IECA 2BWUA 4U6CA 4S00A 3BIQA 1A16A 1WL6A 1XGOA 2G6PA 2Q95A 1YJ3A 3PKAA 1W7VA 3MX6A 1PV9A 4OOKA 1YW8A 4S2TP 5CDEA 3MR1A 4IKSA 4U6ZA 4U6EA 2GA2A 1B6AA 2NQ6A 4PV4A 3L24A 1WN1A 2OKNA 4FLJA 5CIKA 2P9AA 4FO7A 3PKDA 4EGEA 3IU7A 1BOAA 2BHAA 1YW7A 3D27A 1QXZA 2IW2A 1YVMA 4Z7MA 5CE6A 5E5BA 4FLLA 2BWWA 4IKTA 3RVAA 2EVMA 3FM3A 5JHUA 1QZYA 3CB6A 4A6WA 4ZWOA 2NQ7A 1KQ0A 5FCFA 5JI6A 1WL9A 4IF7A 3S6BA 2P99A 5D6EA 2BWTA 2GU4A 3BITA 4KM3A 3L7GA
chains in the Genus database with same CATH superfamily
1C27A 2BB7A 2BWSA 2BN7A 2B3LA 3CB5A 2EVOA 4IKRA 2B3HA 1KQ9A 3RORA 2P98A 4RZZA 2EA2A 4JUQA 4QR8A 1R5HA 1C24A 2OAZA 5CDLA 2BHCA 1R5GA 2GZ5A 2GU6A 4U69A 2GG2A 2Q93A 4MATA 1KP0A 2BH3A 2Q8KA 2V6CA 3PKCA 4FKCA 4FO8A 2GG5A 2GG8A 4PNCA 2Q94A 3IU9A 2BHBA 2V3XA 5CNXA 2V3ZA 4R60A 5D6FA 1CHMA 1MATA 4U6WA 3IG4A 3TAVA 3IU8A 3PKBA 1QXYA 2BWYA 2EA4A 1B59A 2GTXA 4U70A 3CTZA 1Y1NA 2GG0A 1WY2A 2MATA 1M35A 3BIPA 2GG3A 2GG7A 2DFIA 2ADUA 5JFRA 4ZWPA 1C22A 2GGCA 5FCHA 1WLRA 1O0XA 2HOWA 4RGZ1 1C23A 3FMQA 4IPAA 3FMRA 2EVCA 1YW9A 4U73A 4HXXA 4U1BA 1WKMA 4FUKA 5CLSA 2GG9A 1BN5A 1XNZA 4FLIA 1WBQA 4IKUA 2V3YA 4IDYA 4B28A 1R58A 4U75A 3TB5A 4S2RP 4FLKA 4U6JA 4A6VA 2GU7A 2BHDA 1XGMA 1XGNA 4U76A 2Q92A 2GU5A 3PKEA 4RZYA 4ZWUA 2B3KA 2BWVA 4S01A 1W2MA 2ZSGA 1JAWA 4ZNGA 2Q96A 1C21A 2GGBA 4U71A 2BWXA 1N51A 1XGSA 3MATA 5CDVA 4IU6A 1QXWA 3Q6DA 4IECA 2BWUA 4U6CA 4S00A 3BIQA 1A16A 1WL6A 1XGOA 2G6PA 2Q95A 1YJ3A 3PKAA 1W7VA 3MX6A 1PV9A 4OOKA 1YW8A 4S2TP 5CDEA 3MR1A 4IKSA 4U6ZA 4U6EA 2GA2A 1B6AA 2NQ6A 4PV4A 3L24A 1WN1A 2OKNA 4FLJA 5CIKA 2P9AA 4FO7A 3PKDA 4EGEA 3IU7A 1BOAA 2BHAA 1YW7A 3D27A 1QXZA 2IW2A 1YVMA 4Z7MA 5CE6A 5E5BA 4FLLA 2BWWA 4IKTA 3RVAA 2EVMA 3FM3A 5JHUA 1QZYA 3CB6A 4A6WA 4ZWOA 2NQ7A 1KQ0A 5FCFA 5JI6A 1WL9A 4IF7A 3S6BA 2P99A 5D6EA 2BWTA 2GU4A 3BITA 4KM3A 3L7GA
chains in the Genus database with same CATH topology
1C27A 2BB7A 2BWSA 2BN7A 2B3LA 3CB5A 2EVOA 4IKRA 2B3HA 1KQ9A 3RORA 2P98A 4RZZA 2EA2A 4JUQA 4QR8A 1R5HA 1C24A 2OAZA 5CDLA 2BHCA 1R5GA 2GZ5A 2GU6A 4U69A 2GG2A 2Q93A 4MATA 1KP0A 2BH3A 2Q8KA 2V6CA 3PKCA 4FKCA 4FO8A 2GG5A 2GG8A 4PNCA 2Q94A 3IU9A 2BHBA 2V3XA 5CNXA 2V3ZA 4R60A 5D6FA 1CHMA 1MATA 4U6WA 3IG4A 3TAVA 3IU8A 3PKBA 1QXYA 2BWYA 2EA4A 1B59A 2GTXA 4U70A 3CTZA 1Y1NA 2GG0A 1WY2A 2MATA 1M35A 3BIPA 2GG3A 2GG7A 2DFIA 2ADUA 5JFRA 4ZWPA 1C22A 2GGCA 5FCHA 1WLRA 1O0XA 2HOWA 4RGZ1 1C23A 3FMQA 4IPAA 3FMRA 2EVCA 1YW9A 4U73A 4HXXA 4U1BA 1WKMA 4FUKA 5CLSA 2GG9A 1BN5A 1XNZA 4FLIA 1WBQA 4IKUA 2V3YA 4IDYA 4B28A 1R58A 4U75A 3TB5A 4S2RP 4FLKA 4U6JA 4A6VA 2GU7A 2BHDA 1XGMA 1XGNA 4U76A 2Q92A 2GU5A 3PKEA 4RZYA 4ZWUA 2B3KA 2BWVA 4S01A 1W2MA 2ZSGA 1JAWA 4ZNGA 2Q96A 1C21A 2GGBA 4U71A 2BWXA 1N51A 1XGSA 3MATA 5CDVA 4IU6A 1QXWA 3Q6DA 4IECA 2BWUA 4U6CA 4S00A 3BIQA 1A16A 1WL6A 1XGOA 2G6PA 2Q95A 1YJ3A 3PKAA 1W7VA 3MX6A 1PV9A 4OOKA 1YW8A 4S2TP 5CDEA 3MR1A 4IKSA 4U6ZA 4U6EA 2GA2A 1B6AA 2NQ6A 4PV4A 3L24A 1WN1A 2OKNA 4FLJA 5CIKA 2P9AA 4FO7A 3PKDA 4EGEA 3IU7A 1BOAA 2BHAA 1YW7A 3D27A 1QXZA 2IW2A 1YVMA 4Z7MA 5CE6A 5E5BA 4FLLA 2BWWA 4IKTA 3RVAA 2EVMA 3FM3A 5JHUA 1QZYA 3CB6A 4A6WA 4ZWOA 2NQ7A 1KQ0A 5FCFA 5JI6A 1WL9A 4IF7A 3S6BA 2P99A 5D6EA 2BWTA 2GU4A 3BITA 4KM3A 3L7GA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1C27 A;  2BB7 A;  2BWS A;  2BN7 A;  2B3L A;  3CB5 A;  2EVO A;  4IKR A;  2B3H A;  1KQ9 A;  3ROR A;  2P98 A;  4RZZ A;  2EA2 A;  4JUQ A;  4QR8 A;  1R5H A;  1C24 A;  2OAZ A;  5CDL A;  2BHC A;  1R5G A;  2GZ5 A;  2GU6 A;  4U69 A;  2GG2 A;  2Q93 A;  4MAT A;  1KP0 A;  2BH3 A;  2Q8K A;  2V6C A;  3PKC A;  4FKC A;  4FO8 A;  2GG5 A;  2GG8 A;  4PNC A;  2Q94 A;  3IU9 A;  2BHB A;  2V3X A;  5CNX A;  2V3Z A;  4R60 A;  5D6F A;  1CHM A;  1MAT A;  4U6W A;  3IG4 A;  3TAV A;  3IU8 A;  3PKB A;  1QXY A;  2BWY A;  2EA4 A;  1B59 A;  2GTX A;  4U70 A;  3CTZ A;  1Y1N A;  2GG0 A;  1WY2 A;  2MAT A;  1M35 A;  3BIP A;  2GG3 A;  2GG7 A;  2DFI A;  2ADU A;  5JFR A;  4ZWP A;  1C22 A;  2GGC A;  5FCH A;  1WLR A;  1O0X A;  2HOW A;  4RGZ 1;  1C23 A;  3FMQ A;  4IPA A;  3FMR A;  2EVC A;  1YW9 A;  4U73 A;  4HXX A;  4U1B A;  1WKM A;  4FUK A;  5CLS A;  2GG9 A;  1BN5 A;  1XNZ A;  4FLI A;  1WBQ A;  4IKU A;  2V3Y A;  4IDY A;  4B28 A;  1R58 A;  4U75 A;  3TB5 A;  4S2R P;  4FLK A;  4U6J A;  4A6V A;  2GU7 A;  2BHD A;  1XGM A;  1XGN A;  4U76 A;  2Q92 A;  2GU5 A;  3PKE A;  4RZY A;  4ZWU A;  2B3K A;  2BWV A;  4S01 A;  1W2M A;  2ZSG A;  1JAW A;  4ZNG A;  2Q96 A;  1C21 A;  2GGB A;  4U71 A;  2BWX A;  1N51 A;  1XGS A;  3MAT A;  5CDV A;  4IU6 A;  1QXW A;  3Q6D A;  4IEC A;  2BWU A;  4U6C A;  4S00 A;  3BIQ A;  1A16 A;  1WL6 A;  1XGO A;  2G6P A;  2Q95 A;  1YJ3 A;  3PKA A;  1W7V A;  3MX6 A;  1PV9 A;  4OOK A;  1YW8 A;  4S2T P;  5CDE A;  3MR1 A;  4IKS A;  4U6Z A;  4U6E A;  2GA2 A;  1B6A A;  2NQ6 A;  4PV4 A;  3L24 A;  1WN1 A;  2OKN A;  4FLJ A;  5CIK A;  2P9A A;  4FO7 A;  3PKD A;  4EGE A;  3IU7 A;  1BOA A;  2BHA A;  1YW7 A;  3D27 A;  1QXZ A;  2IW2 A;  1YVM A;  4Z7M A;  5CE6 A;  5E5B A;  4FLL A;  2BWW A;  4IKT A;  3RVA A;  2EVM A;  3FM3 A;  5JHU A;  1QZY A;  3CB6 A;  4A6W A;  4ZWO A;  2NQ7 A;  1KQ0 A;  5FCF A;  5JI6 A;  1WL9 A;  4IF7 A;  3S6B A;  2P99 A;  5D6E A;  2BWT A;  2GU4 A;  3BIT A;  4KM3 A;  3L7G A; 
#chains in the Genus database with same CATH topology
 1C27 A;  2BB7 A;  2BWS A;  2BN7 A;  2B3L A;  3CB5 A;  2EVO A;  4IKR A;  2B3H A;  1KQ9 A;  3ROR A;  2P98 A;  4RZZ A;  2EA2 A;  4JUQ A;  4QR8 A;  1R5H A;  1C24 A;  2OAZ A;  5CDL A;  2BHC A;  1R5G A;  2GZ5 A;  2GU6 A;  4U69 A;  2GG2 A;  2Q93 A;  4MAT A;  1KP0 A;  2BH3 A;  2Q8K A;  2V6C A;  3PKC A;  4FKC A;  4FO8 A;  2GG5 A;  2GG8 A;  4PNC A;  2Q94 A;  3IU9 A;  2BHB A;  2V3X A;  5CNX A;  2V3Z A;  4R60 A;  5D6F A;  1CHM A;  1MAT A;  4U6W A;  3IG4 A;  3TAV A;  3IU8 A;  3PKB A;  1QXY A;  2BWY A;  2EA4 A;  1B59 A;  2GTX A;  4U70 A;  3CTZ A;  1Y1N A;  2GG0 A;  1WY2 A;  2MAT A;  1M35 A;  3BIP A;  2GG3 A;  2GG7 A;  2DFI A;  2ADU A;  5JFR A;  4ZWP A;  1C22 A;  2GGC A;  5FCH A;  1WLR A;  1O0X A;  2HOW A;  4RGZ 1;  1C23 A;  3FMQ A;  4IPA A;  3FMR A;  2EVC A;  1YW9 A;  4U73 A;  4HXX A;  4U1B A;  1WKM A;  4FUK A;  5CLS A;  2GG9 A;  1BN5 A;  1XNZ A;  4FLI A;  1WBQ A;  4IKU A;  2V3Y A;  4IDY A;  4B28 A;  1R58 A;  4U75 A;  3TB5 A;  4S2R P;  4FLK A;  4U6J A;  4A6V A;  2GU7 A;  2BHD A;  1XGM A;  1XGN A;  4U76 A;  2Q92 A;  2GU5 A;  3PKE A;  4RZY A;  4ZWU A;  2B3K A;  2BWV A;  4S01 A;  1W2M A;  2ZSG A;  1JAW A;  4ZNG A;  2Q96 A;  1C21 A;  2GGB A;  4U71 A;  2BWX A;  1N51 A;  1XGS A;  3MAT A;  5CDV A;  4IU6 A;  1QXW A;  3Q6D A;  4IEC A;  2BWU A;  4U6C A;  4S00 A;  3BIQ A;  1A16 A;  1WL6 A;  1XGO A;  2G6P A;  2Q95 A;  1YJ3 A;  3PKA A;  1W7V A;  3MX6 A;  1PV9 A;  4OOK A;  1YW8 A;  4S2T P;  5CDE A;  3MR1 A;  4IKS A;  4U6Z A;  4U6E A;  2GA2 A;  1B6A A;  2NQ6 A;  4PV4 A;  3L24 A;  1WN1 A;  2OKN A;  4FLJ A;  5CIK A;  2P9A A;  4FO7 A;  3PKD A;  4EGE A;  3IU7 A;  1BOA A;  2BHA A;  1YW7 A;  3D27 A;  1QXZ A;  2IW2 A;  1YVM A;  4Z7M A;  5CE6 A;  5E5B A;  4FLL A;  2BWW A;  4IKT A;  3RVA A;  2EVM A;  3FM3 A;  5JHU A;  1QZY A;  3CB6 A;  4A6W A;  4ZWO A;  2NQ7 A;  1KQ0 A;  5FCF A;  5JI6 A;  1WL9 A;  4IF7 A;  3S6B A;  2P99 A;  5D6E A;  2BWT A;  2GU4 A;  3BIT A;  4KM3 A;  3L7G A; 
#chains in the Genus database with same CATH homology
 1C27 A;  2BB7 A;  2BWS A;  2BN7 A;  2B3L A;  3CB5 A;  2EVO A;  4IKR A;  2B3H A;  1KQ9 A;  3ROR A;  2P98 A;  4RZZ A;  2EA2 A;  4JUQ A;  4QR8 A;  1R5H A;  1C24 A;  2OAZ A;  5CDL A;  2BHC A;  1R5G A;  2GZ5 A;  2GU6 A;  4U69 A;  2GG2 A;  2Q93 A;  4MAT A;  1KP0 A;  2BH3 A;  2Q8K A;  2V6C A;  3PKC A;  4FKC A;  4FO8 A;  2GG5 A;  2GG8 A;  4PNC A;  2Q94 A;  3IU9 A;  2BHB A;  2V3X A;  5CNX A;  2V3Z A;  4R60 A;  5D6F A;  1CHM A;  1MAT A;  4U6W A;  3IG4 A;  3TAV A;  3IU8 A;  3PKB A;  1QXY A;  2BWY A;  2EA4 A;  1B59 A;  2GTX A;  4U70 A;  3CTZ A;  1Y1N A;  2GG0 A;  1WY2 A;  2MAT A;  1M35 A;  3BIP A;  2GG3 A;  2GG7 A;  2DFI A;  2ADU A;  5JFR A;  4ZWP A;  1C22 A;  2GGC A;  5FCH A;  1WLR A;  1O0X A;  2HOW A;  4RGZ 1;  1C23 A;  3FMQ A;  4IPA A;  3FMR A;  2EVC A;  1YW9 A;  4U73 A;  4HXX A;  4U1B A;  1WKM A;  4FUK A;  5CLS A;  2GG9 A;  1BN5 A;  1XNZ A;  4FLI A;  1WBQ A;  4IKU A;  2V3Y A;  4IDY A;  4B28 A;  1R58 A;  4U75 A;  3TB5 A;  4S2R P;  4FLK A;  4U6J A;  4A6V A;  2GU7 A;  2BHD A;  1XGM A;  1XGN A;  4U76 A;  2Q92 A;  2GU5 A;  3PKE A;  4RZY A;  4ZWU A;  2B3K A;  2BWV A;  4S01 A;  1W2M A;  2ZSG A;  1JAW A;  4ZNG A;  2Q96 A;  1C21 A;  2GGB A;  4U71 A;  2BWX A;  1N51 A;  1XGS A;  3MAT A;  5CDV A;  4IU6 A;  1QXW A;  3Q6D A;  4IEC A;  2BWU A;  4U6C A;  4S00 A;  3BIQ A;  1A16 A;  1WL6 A;  1XGO A;  2G6P A;  2Q95 A;  1YJ3 A;  3PKA A;  1W7V A;  3MX6 A;  1PV9 A;  4OOK A;  1YW8 A;  4S2T P;  5CDE A;  3MR1 A;  4IKS A;  4U6Z A;  4U6E A;  2GA2 A;  1B6A A;  2NQ6 A;  4PV4 A;  3L24 A;  1WN1 A;  2OKN A;  4FLJ A;  5CIK A;  2P9A A;  4FO7 A;  3PKD A;  4EGE A;  3IU7 A;  1BOA A;  2BHA A;  1YW7 A;  3D27 A;  1QXZ A;  2IW2 A;  1YVM A;  4Z7M A;  5CE6 A;  5E5B A;  4FLL A;  2BWW A;  4IKT A;  3RVA A;  2EVM A;  3FM3 A;  5JHU A;  1QZY A;  3CB6 A;  4A6W A;  4ZWO A;  2NQ7 A;  1KQ0 A;  5FCF A;  5JI6 A;  1WL9 A;  4IF7 A;  3S6B A;  2P99 A;  5D6E A;  2BWT A;  2GU4 A;  3BIT A;  4KM3 A;  3L7G A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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