3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
5CIKA 2DFIA 4RZYA 2NQ6A 2EVMA 5CNXA 1BOAA 4A6WA 1WL9A 4U75A 2ZSGA 5E5BA 4ZWUA 1WL6A 5FCFA 5JHUA 1XNZA 1N51A 1YW9A 2B3LA 2BHCA 3IU8A 4PNCA 4U69A 2EA2A 3IG4A 1C27A 1WKMA 1QXYA 2EVOA 4U1BA 4FO8A 3CTZA 3FM3A 4ZWPA 2BWYA 1R5GA 1C22A 3S6BA 4R60A 4U70A 1W7VA 2BB7A 1QXZA 2BHBA 1A16A 1R5HA 4IPAA 5D6EA 2V3XA 4MATA 4EGEA 1QXWA 2GA2A 4U6WA 1KP0A 2Q93A 1YJ3A 1MATA 2BN7A 4IKTA 4RGZ1 2BWTA 1WY2A 1YVMA 3D27A 2IW2A 4ZNGA 2GG5A 4IU6A 3PKCA 2Q8KA 2OAZA 1R58A 4ZWOA 4IDYA 5CE6A 3L24A 4FLJA 2BWSA 4JUQA 4U71A 5JI6A 1B6AA 3PKBA 5CDEA 1C24A 1XGSA 4U6JA 5CDLA 2NQ7A 2HOWA 3MX6A 3MATA 2Q96A 5FCHA 2GU5A 1YW7A 3BITA 4S2TP 2GU6A 2EVCA 4U6EA 2Q94A 2BWUA 2B3HA 4IECA 2MATA 4S2RP 1Y1NA 1XGOA 1BN5A 2GG8A 4IF7A 2GGBA 2BWXA 4Z7MA 2GG7A 3PKAA 5CDVA 3PKDA 3RVAA 1M35A 2OKNA 4FLIA 2GG0A 2BWWA 3PKEA 3BIPA 4FUKA 2EA4A 2GG3A 4OOKA 2P99A 2GGCA 1B59A 4PV4A 2Q95A 3TB5A 1XGMA 4U6ZA 2GU7A 3MR1A 3RORA 3FMRA 3IU7A 4U76A 3TAVA 4FKCA 4S01A 2GG9A 2V3ZA 2GTXA 2GZ5A 1WBQA 1W2MA 1CHMA 1KQ9A 5D6FA 2BH3A 2BHDA 1XGNA 4B28A 1YW8A 2V6CA 3CB5A 5JFRA 4IKUA 2GU4A 1QZYA 4FLKA 2ADUA 2V3YA 4RZZA 3CB6A 1KQ0A 4KM3A 4U73A 3FMQA 4HXXA 2Q92A 2GG2A 1JAWA 2P98A 2BWVA 3IU9A 4IKSA 3Q6DA 4QR8A 1PV9A 1C23A 4FLLA 4FO7A 2G6PA 5CLSA 4S00A 4U6CA 2B3KA 2P9AA 1C21A 1O0XA 1WN1A 1WLRA 3L7GA 4A6VA 3BIQA 2BHAA 4IKRA
chains in the Genus database with same CATH superfamily
5CIKA 2DFIA 4RZYA 2NQ6A 2EVMA 5CNXA 1BOAA 4A6WA 1WL9A 4U75A 2ZSGA 5E5BA 4ZWUA 1WL6A 5FCFA 5JHUA 1XNZA 1N51A 1YW9A 2B3LA 2BHCA 3IU8A 4PNCA 4U69A 2EA2A 3IG4A 1C27A 1WKMA 1QXYA 2EVOA 4U1BA 4FO8A 3CTZA 3FM3A 4ZWPA 2BWYA 1R5GA 1C22A 3S6BA 4R60A 4U70A 1W7VA 2BB7A 1QXZA 2BHBA 1A16A 1R5HA 4IPAA 5D6EA 2V3XA 4MATA 4EGEA 1QXWA 2GA2A 4U6WA 1KP0A 2Q93A 1YJ3A 1MATA 2BN7A 4IKTA 4RGZ1 2BWTA 1WY2A 1YVMA 3D27A 2IW2A 4ZNGA 2GG5A 4IU6A 3PKCA 2Q8KA 2OAZA 1R58A 4ZWOA 4IDYA 5CE6A 3L24A 4FLJA 2BWSA 4JUQA 4U71A 5JI6A 1B6AA 3PKBA 5CDEA 1C24A 1XGSA 4U6JA 5CDLA 2NQ7A 2HOWA 3MX6A 3MATA 2Q96A 5FCHA 2GU5A 1YW7A 3BITA 4S2TP 2GU6A 2EVCA 4U6EA 2Q94A 2BWUA 2B3HA 4IECA 2MATA 4S2RP 1Y1NA 1XGOA 1BN5A 2GG8A 4IF7A 2GGBA 2BWXA 4Z7MA 2GG7A 3PKAA 5CDVA 3PKDA 3RVAA 1M35A 2OKNA 4FLIA 2GG0A 2BWWA 3PKEA 3BIPA 4FUKA 2EA4A 2GG3A 4OOKA 2P99A 2GGCA 1B59A 4PV4A 2Q95A 3TB5A 1XGMA 4U6ZA 2GU7A 3MR1A 3RORA 3FMRA 3IU7A 4U76A 3TAVA 4FKCA 4S01A 2GG9A 2V3ZA 2GTXA 2GZ5A 1WBQA 1W2MA 1CHMA 1KQ9A 5D6FA 2BH3A 2BHDA 1XGNA 4B28A 1YW8A 2V6CA 3CB5A 5JFRA 4IKUA 2GU4A 1QZYA 4FLKA 2ADUA 2V3YA 4RZZA 3CB6A 1KQ0A 4KM3A 4U73A 3FMQA 4HXXA 2Q92A 2GG2A 1JAWA 2P98A 2BWVA 3IU9A 4IKSA 3Q6DA 4QR8A 1PV9A 1C23A 4FLLA 4FO7A 2G6PA 5CLSA 4S00A 4U6CA 2B3KA 2P9AA 1C21A 1O0XA 1WN1A 1WLRA 3L7GA 4A6VA 3BIQA 2BHAA 4IKRA
chains in the Genus database with same CATH topology
5CIKA 2DFIA 4RZYA 2NQ6A 2EVMA 5CNXA 1BOAA 4A6WA 1WL9A 4U75A 2ZSGA 5E5BA 4ZWUA 1WL6A 5FCFA 5JHUA 1XNZA 1N51A 1YW9A 2B3LA 2BHCA 3IU8A 4PNCA 4U69A 2EA2A 3IG4A 1C27A 1WKMA 1QXYA 2EVOA 4U1BA 4FO8A 3CTZA 3FM3A 4ZWPA 2BWYA 1R5GA 1C22A 3S6BA 4R60A 4U70A 1W7VA 2BB7A 1QXZA 2BHBA 1A16A 1R5HA 4IPAA 5D6EA 2V3XA 4MATA 4EGEA 1QXWA 2GA2A 4U6WA 1KP0A 2Q93A 1YJ3A 1MATA 2BN7A 4IKTA 4RGZ1 2BWTA 1WY2A 1YVMA 3D27A 2IW2A 4ZNGA 2GG5A 4IU6A 3PKCA 2Q8KA 2OAZA 1R58A 4ZWOA 4IDYA 5CE6A 3L24A 4FLJA 2BWSA 4JUQA 4U71A 5JI6A 1B6AA 3PKBA 5CDEA 1C24A 1XGSA 4U6JA 5CDLA 2NQ7A 2HOWA 3MX6A 3MATA 2Q96A 5FCHA 2GU5A 1YW7A 3BITA 4S2TP 2GU6A 2EVCA 4U6EA 2Q94A 2BWUA 2B3HA 4IECA 2MATA 4S2RP 1Y1NA 1XGOA 1BN5A 2GG8A 4IF7A 2GGBA 2BWXA 4Z7MA 2GG7A 3PKAA 5CDVA 3PKDA 3RVAA 1M35A 2OKNA 4FLIA 2GG0A 2BWWA 3PKEA 3BIPA 4FUKA 2EA4A 2GG3A 4OOKA 2P99A 2GGCA 1B59A 4PV4A 2Q95A 3TB5A 1XGMA 4U6ZA 2GU7A 3MR1A 3RORA 3FMRA 3IU7A 4U76A 3TAVA 4FKCA 4S01A 2GG9A 2V3ZA 2GTXA 2GZ5A 1WBQA 1W2MA 1CHMA 1KQ9A 5D6FA 2BH3A 2BHDA 1XGNA 4B28A 1YW8A 2V6CA 3CB5A 5JFRA 4IKUA 2GU4A 1QZYA 4FLKA 2ADUA 2V3YA 4RZZA 3CB6A 1KQ0A 4KM3A 4U73A 3FMQA 4HXXA 2Q92A 2GG2A 1JAWA 2P98A 2BWVA 3IU9A 4IKSA 3Q6DA 4QR8A 1PV9A 1C23A 4FLLA 4FO7A 2G6PA 5CLSA 4S00A 4U6CA 2B3KA 2P9AA 1C21A 1O0XA 1WN1A 1WLRA 3L7GA 4A6VA 3BIQA 2BHAA 4IKRA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5CIK A;  2DFI A;  4RZY A;  2NQ6 A;  2EVM A;  5CNX A;  1BOA A;  4A6W A;  1WL9 A;  4U75 A;  2ZSG A;  5E5B A;  4ZWU A;  1WL6 A;  5FCF A;  5JHU A;  1XNZ A;  1N51 A;  1YW9 A;  2B3L A;  2BHC A;  3IU8 A;  4PNC A;  4U69 A;  2EA2 A;  3IG4 A;  1C27 A;  1WKM A;  1QXY A;  2EVO A;  4U1B A;  4FO8 A;  3CTZ A;  3FM3 A;  4ZWP A;  2BWY A;  1R5G A;  1C22 A;  3S6B A;  4R60 A;  4U70 A;  1W7V A;  2BB7 A;  1QXZ A;  2BHB A;  1A16 A;  1R5H A;  4IPA A;  5D6E A;  2V3X A;  4MAT A;  4EGE A;  1QXW A;  2GA2 A;  4U6W A;  1KP0 A;  2Q93 A;  1YJ3 A;  1MAT A;  2BN7 A;  4IKT A;  4RGZ 1;  2BWT A;  1WY2 A;  1YVM A;  3D27 A;  2IW2 A;  4ZNG A;  2GG5 A;  4IU6 A;  3PKC A;  2Q8K A;  2OAZ A;  1R58 A;  4ZWO A;  4IDY A;  5CE6 A;  3L24 A;  4FLJ A;  2BWS A;  4JUQ A;  4U71 A;  5JI6 A;  1B6A A;  3PKB A;  5CDE A;  1C24 A;  1XGS A;  4U6J A;  5CDL A;  2NQ7 A;  2HOW A;  3MX6 A;  3MAT A;  2Q96 A;  5FCH A;  2GU5 A;  1YW7 A;  3BIT A;  4S2T P;  2GU6 A;  2EVC A;  4U6E A;  2Q94 A;  2BWU A;  2B3H A;  4IEC A;  2MAT A;  4S2R P;  1Y1N A;  1XGO A;  1BN5 A;  2GG8 A;  4IF7 A;  2GGB A;  2BWX A;  4Z7M A;  2GG7 A;  3PKA A;  5CDV A;  3PKD A;  3RVA A;  1M35 A;  2OKN A;  4FLI A;  2GG0 A;  2BWW A;  3PKE A;  3BIP A;  4FUK A;  2EA4 A;  2GG3 A;  4OOK A;  2P99 A;  2GGC A;  1B59 A;  4PV4 A;  2Q95 A;  3TB5 A;  1XGM A;  4U6Z A;  2GU7 A;  3MR1 A;  3ROR A;  3FMR A;  3IU7 A;  4U76 A;  3TAV A;  4FKC A;  4S01 A;  2GG9 A;  2V3Z A;  2GTX A;  2GZ5 A;  1WBQ A;  1W2M A;  1CHM A;  1KQ9 A;  5D6F A;  2BH3 A;  2BHD A;  1XGN A;  4B28 A;  1YW8 A;  2V6C A;  3CB5 A;  5JFR A;  4IKU A;  2GU4 A;  1QZY A;  4FLK A;  2ADU A;  2V3Y A;  4RZZ A;  3CB6 A;  1KQ0 A;  4KM3 A;  4U73 A;  3FMQ A;  4HXX A;  2Q92 A;  2GG2 A;  1JAW A;  2P98 A;  2BWV A;  3IU9 A;  4IKS A;  3Q6D A;  4QR8 A;  1PV9 A;  1C23 A;  4FLL A;  4FO7 A;  2G6P A;  5CLS A;  4S00 A;  4U6C A;  2B3K A;  2P9A A;  1C21 A;  1O0X A;  1WN1 A;  1WLR A;  3L7G A;  4A6V A;  3BIQ A;  2BHA A;  4IKR A; 
#chains in the Genus database with same CATH topology
 5CIK A;  2DFI A;  4RZY A;  2NQ6 A;  2EVM A;  5CNX A;  1BOA A;  4A6W A;  1WL9 A;  4U75 A;  2ZSG A;  5E5B A;  4ZWU A;  1WL6 A;  5FCF A;  5JHU A;  1XNZ A;  1N51 A;  1YW9 A;  2B3L A;  2BHC A;  3IU8 A;  4PNC A;  4U69 A;  2EA2 A;  3IG4 A;  1C27 A;  1WKM A;  1QXY A;  2EVO A;  4U1B A;  4FO8 A;  3CTZ A;  3FM3 A;  4ZWP A;  2BWY A;  1R5G A;  1C22 A;  3S6B A;  4R60 A;  4U70 A;  1W7V A;  2BB7 A;  1QXZ A;  2BHB A;  1A16 A;  1R5H A;  4IPA A;  5D6E A;  2V3X A;  4MAT A;  4EGE A;  1QXW A;  2GA2 A;  4U6W A;  1KP0 A;  2Q93 A;  1YJ3 A;  1MAT A;  2BN7 A;  4IKT A;  4RGZ 1;  2BWT A;  1WY2 A;  1YVM A;  3D27 A;  2IW2 A;  4ZNG A;  2GG5 A;  4IU6 A;  3PKC A;  2Q8K A;  2OAZ A;  1R58 A;  4ZWO A;  4IDY A;  5CE6 A;  3L24 A;  4FLJ A;  2BWS A;  4JUQ A;  4U71 A;  5JI6 A;  1B6A A;  3PKB A;  5CDE A;  1C24 A;  1XGS A;  4U6J A;  5CDL A;  2NQ7 A;  2HOW A;  3MX6 A;  3MAT A;  2Q96 A;  5FCH A;  2GU5 A;  1YW7 A;  3BIT A;  4S2T P;  2GU6 A;  2EVC A;  4U6E A;  2Q94 A;  2BWU A;  2B3H A;  4IEC A;  2MAT A;  4S2R P;  1Y1N A;  1XGO A;  1BN5 A;  2GG8 A;  4IF7 A;  2GGB A;  2BWX A;  4Z7M A;  2GG7 A;  3PKA A;  5CDV A;  3PKD A;  3RVA A;  1M35 A;  2OKN A;  4FLI A;  2GG0 A;  2BWW A;  3PKE A;  3BIP A;  4FUK A;  2EA4 A;  2GG3 A;  4OOK A;  2P99 A;  2GGC A;  1B59 A;  4PV4 A;  2Q95 A;  3TB5 A;  1XGM A;  4U6Z A;  2GU7 A;  3MR1 A;  3ROR A;  3FMR A;  3IU7 A;  4U76 A;  3TAV A;  4FKC A;  4S01 A;  2GG9 A;  2V3Z A;  2GTX A;  2GZ5 A;  1WBQ A;  1W2M A;  1CHM A;  1KQ9 A;  5D6F A;  2BH3 A;  2BHD A;  1XGN A;  4B28 A;  1YW8 A;  2V6C A;  3CB5 A;  5JFR A;  4IKU A;  2GU4 A;  1QZY A;  4FLK A;  2ADU A;  2V3Y A;  4RZZ A;  3CB6 A;  1KQ0 A;  4KM3 A;  4U73 A;  3FMQ A;  4HXX A;  2Q92 A;  2GG2 A;  1JAW A;  2P98 A;  2BWV A;  3IU9 A;  4IKS A;  3Q6D A;  4QR8 A;  1PV9 A;  1C23 A;  4FLL A;  4FO7 A;  2G6P A;  5CLS A;  4S00 A;  4U6C A;  2B3K A;  2P9A A;  1C21 A;  1O0X A;  1WN1 A;  1WLR A;  3L7G A;  4A6V A;  3BIQ A;  2BHA A;  4IKR A; 
#chains in the Genus database with same CATH homology
 5CIK A;  2DFI A;  4RZY A;  2NQ6 A;  2EVM A;  5CNX A;  1BOA A;  4A6W A;  1WL9 A;  4U75 A;  2ZSG A;  5E5B A;  4ZWU A;  1WL6 A;  5FCF A;  5JHU A;  1XNZ A;  1N51 A;  1YW9 A;  2B3L A;  2BHC A;  3IU8 A;  4PNC A;  4U69 A;  2EA2 A;  3IG4 A;  1C27 A;  1WKM A;  1QXY A;  2EVO A;  4U1B A;  4FO8 A;  3CTZ A;  3FM3 A;  4ZWP A;  2BWY A;  1R5G A;  1C22 A;  3S6B A;  4R60 A;  4U70 A;  1W7V A;  2BB7 A;  1QXZ A;  2BHB A;  1A16 A;  1R5H A;  4IPA A;  5D6E A;  2V3X A;  4MAT A;  4EGE A;  1QXW A;  2GA2 A;  4U6W A;  1KP0 A;  2Q93 A;  1YJ3 A;  1MAT A;  2BN7 A;  4IKT A;  4RGZ 1;  2BWT A;  1WY2 A;  1YVM A;  3D27 A;  2IW2 A;  4ZNG A;  2GG5 A;  4IU6 A;  3PKC A;  2Q8K A;  2OAZ A;  1R58 A;  4ZWO A;  4IDY A;  5CE6 A;  3L24 A;  4FLJ A;  2BWS A;  4JUQ A;  4U71 A;  5JI6 A;  1B6A A;  3PKB A;  5CDE A;  1C24 A;  1XGS A;  4U6J A;  5CDL A;  2NQ7 A;  2HOW A;  3MX6 A;  3MAT A;  2Q96 A;  5FCH A;  2GU5 A;  1YW7 A;  3BIT A;  4S2T P;  2GU6 A;  2EVC A;  4U6E A;  2Q94 A;  2BWU A;  2B3H A;  4IEC A;  2MAT A;  4S2R P;  1Y1N A;  1XGO A;  1BN5 A;  2GG8 A;  4IF7 A;  2GGB A;  2BWX A;  4Z7M A;  2GG7 A;  3PKA A;  5CDV A;  3PKD A;  3RVA A;  1M35 A;  2OKN A;  4FLI A;  2GG0 A;  2BWW A;  3PKE A;  3BIP A;  4FUK A;  2EA4 A;  2GG3 A;  4OOK A;  2P99 A;  2GGC A;  1B59 A;  4PV4 A;  2Q95 A;  3TB5 A;  1XGM A;  4U6Z A;  2GU7 A;  3MR1 A;  3ROR A;  3FMR A;  3IU7 A;  4U76 A;  3TAV A;  4FKC A;  4S01 A;  2GG9 A;  2V3Z A;  2GTX A;  2GZ5 A;  1WBQ A;  1W2M A;  1CHM A;  1KQ9 A;  5D6F A;  2BH3 A;  2BHD A;  1XGN A;  4B28 A;  1YW8 A;  2V6C A;  3CB5 A;  5JFR A;  4IKU A;  2GU4 A;  1QZY A;  4FLK A;  2ADU A;  2V3Y A;  4RZZ A;  3CB6 A;  1KQ0 A;  4KM3 A;  4U73 A;  3FMQ A;  4HXX A;  2Q92 A;  2GG2 A;  1JAW A;  2P98 A;  2BWV A;  3IU9 A;  4IKS A;  3Q6D A;  4QR8 A;  1PV9 A;  1C23 A;  4FLL A;  4FO7 A;  2G6P A;  5CLS A;  4S00 A;  4U6C A;  2B3K A;  2P9A A;  1C21 A;  1O0X A;  1WN1 A;  1WLR A;  3L7G A;  4A6V A;  3BIQ A;  2BHA A;  4IKR A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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