3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
2EA4A 2NQ7A 4PV4A 5CNXA 1C27A 3TB5A 1R5HA 3FMRA 1KQ9A 1C24A 4U73A 2BWYA 1CHMA 4IKRA 1O0XA 2GG9A 1Y1NA 4U6EA 4FO7A 1MATA 3RVAA 4FLKA 3PKBA 4FLLA 5D6FA 5CDLA 3IG4A 2B3LA 2Q8KA 1M35A 1YW7A 3PKCA 4S2RP 1BOAA 1QXYA 2GGCA 3PKEA 2Q92A 2V6CA 3RORA 2GU7A 3MR1A 3PKDA 1N51A 3IU9A 5D6EA 5FCHA 1YJ3A 2Q96A 2GA2A 2GGBA 4U6JA 2G6PA 4FLIA 1R5GA 2GU4A 3BIPA 2BHAA 4U69A 1B59A 3CB5A 1PV9A 5FCFA 1A16A 2HOWA 4PNCA 2GG7A 2GG3A 4IDYA 5JI6A 1YW8A 2EA2A 4KM3A 1C22A 2BWUA 3FM3A 4ZWPA 4S00A 1XGOA 1KQ0A 2V3ZA 4U70A 1XGMA 3D27A 2BHBA 4FLJA 4U71A 2EVOA 1WN1A 1WY2A 4Z7MA 1WL6A 4IECA 3MX6A 5JHUA 1XGSA 1WBQA 1XNZA 2BWSA 3FMQA 4RZYA 1R58A 4A6WA 5CIKA 2GG5A 2DFIA 4IF7A 2P9AA 3CB6A 2GU6A 4U6WA 4IKUA 2Q93A 5CDEA 1QZYA 1B6AA 2Q94A 2GG2A 2BHCA 3BIQA 4IPAA 5CE6A 2BWTA 1C23A 5CDVA 4U6ZA 5JFRA 2BN7A 4ZNGA 1W7VA 3IU7A 4OOKA 2OKNA 1WL9A 1JAWA 2GG0A 2GU5A 4ZWUA 3S6BA 4A6VA 2GTXA 2EVMA 4IKSA 2B3HA 2BH3A 5CLSA 2MATA 1YVMA 1C21A 1QXZA 1BN5A 3Q6DA 4RZZA 4B28A 3MATA 4FO8A 2NQ6A 2BWVA 4R60A 4MATA 2GG8A 2ZSGA 1WKMA 4FUKA 4EGEA 2BB7A 2V3XA 4U1BA 2P99A 1KP0A 3BITA 1WLRA 3L24A 4U75A 2OAZA 4HXXA 2ADUA 4JUQA 2V3YA 3PKAA 3IU8A 4S2TP 2GZ5A 2BWWA 2Q95A 4ZWOA 4IKTA 4RGZ1 4FKCA 5E5BA 4S01A 2BHDA 3TAVA 2B3KA 4IU6A 2IW2A 3L7GA 4QR8A 1YW9A 4U76A 1XGNA 3CTZA 2P98A 1W2MA 2BWXA 1QXWA 4U6CA 2EVCA
chains in the Genus database with same CATH superfamily
2EA4A 2NQ7A 4PV4A 5CNXA 1C27A 3TB5A 1R5HA 3FMRA 1KQ9A 1C24A 4U73A 2BWYA 1CHMA 4IKRA 1O0XA 2GG9A 1Y1NA 4U6EA 4FO7A 1MATA 3RVAA 4FLKA 3PKBA 4FLLA 5D6FA 5CDLA 3IG4A 2B3LA 2Q8KA 1M35A 1YW7A 3PKCA 4S2RP 1BOAA 1QXYA 2GGCA 3PKEA 2Q92A 2V6CA 3RORA 2GU7A 3MR1A 3PKDA 1N51A 3IU9A 5D6EA 5FCHA 1YJ3A 2Q96A 2GA2A 2GGBA 4U6JA 2G6PA 4FLIA 1R5GA 2GU4A 3BIPA 2BHAA 4U69A 1B59A 3CB5A 1PV9A 5FCFA 1A16A 2HOWA 4PNCA 2GG7A 2GG3A 4IDYA 5JI6A 1YW8A 2EA2A 4KM3A 1C22A 2BWUA 3FM3A 4ZWPA 4S00A 1XGOA 1KQ0A 2V3ZA 4U70A 1XGMA 3D27A 2BHBA 4FLJA 4U71A 2EVOA 1WN1A 1WY2A 4Z7MA 1WL6A 4IECA 3MX6A 5JHUA 1XGSA 1WBQA 1XNZA 2BWSA 3FMQA 4RZYA 1R58A 4A6WA 5CIKA 2GG5A 2DFIA 4IF7A 2P9AA 3CB6A 2GU6A 4U6WA 4IKUA 2Q93A 5CDEA 1QZYA 1B6AA 2Q94A 2GG2A 2BHCA 3BIQA 4IPAA 5CE6A 2BWTA 1C23A 5CDVA 4U6ZA 5JFRA 2BN7A 4ZNGA 1W7VA 3IU7A 4OOKA 2OKNA 1WL9A 1JAWA 2GG0A 2GU5A 4ZWUA 3S6BA 4A6VA 2GTXA 2EVMA 4IKSA 2B3HA 2BH3A 5CLSA 2MATA 1YVMA 1C21A 1QXZA 1BN5A 3Q6DA 4RZZA 4B28A 3MATA 4FO8A 2NQ6A 2BWVA 4R60A 4MATA 2GG8A 2ZSGA 1WKMA 4FUKA 4EGEA 2BB7A 2V3XA 4U1BA 2P99A 1KP0A 3BITA 1WLRA 3L24A 4U75A 2OAZA 4HXXA 2ADUA 4JUQA 2V3YA 3PKAA 3IU8A 4S2TP 2GZ5A 2BWWA 2Q95A 4ZWOA 4IKTA 4RGZ1 4FKCA 5E5BA 4S01A 2BHDA 3TAVA 2B3KA 4IU6A 2IW2A 3L7GA 4QR8A 1YW9A 4U76A 1XGNA 3CTZA 2P98A 1W2MA 2BWXA 1QXWA 4U6CA 2EVCA
chains in the Genus database with same CATH topology
2EA4A 2NQ7A 4PV4A 5CNXA 1C27A 3TB5A 1R5HA 3FMRA 1KQ9A 1C24A 4U73A 2BWYA 1CHMA 4IKRA 1O0XA 2GG9A 1Y1NA 4U6EA 4FO7A 1MATA 3RVAA 4FLKA 3PKBA 4FLLA 5D6FA 5CDLA 3IG4A 2B3LA 2Q8KA 1M35A 1YW7A 3PKCA 4S2RP 1BOAA 1QXYA 2GGCA 3PKEA 2Q92A 2V6CA 3RORA 2GU7A 3MR1A 3PKDA 1N51A 3IU9A 5D6EA 5FCHA 1YJ3A 2Q96A 2GA2A 2GGBA 4U6JA 2G6PA 4FLIA 1R5GA 2GU4A 3BIPA 2BHAA 4U69A 1B59A 3CB5A 1PV9A 5FCFA 1A16A 2HOWA 4PNCA 2GG7A 2GG3A 4IDYA 5JI6A 1YW8A 2EA2A 4KM3A 1C22A 2BWUA 3FM3A 4ZWPA 4S00A 1XGOA 1KQ0A 2V3ZA 4U70A 1XGMA 3D27A 2BHBA 4FLJA 4U71A 2EVOA 1WN1A 1WY2A 4Z7MA 1WL6A 4IECA 3MX6A 5JHUA 1XGSA 1WBQA 1XNZA 2BWSA 3FMQA 4RZYA 1R58A 4A6WA 5CIKA 2GG5A 2DFIA 4IF7A 2P9AA 3CB6A 2GU6A 4U6WA 4IKUA 2Q93A 5CDEA 1QZYA 1B6AA 2Q94A 2GG2A 2BHCA 3BIQA 4IPAA 5CE6A 2BWTA 1C23A 5CDVA 4U6ZA 5JFRA 2BN7A 4ZNGA 1W7VA 3IU7A 4OOKA 2OKNA 1WL9A 1JAWA 2GG0A 2GU5A 4ZWUA 3S6BA 4A6VA 2GTXA 2EVMA 4IKSA 2B3HA 2BH3A 5CLSA 2MATA 1YVMA 1C21A 1QXZA 1BN5A 3Q6DA 4RZZA 4B28A 3MATA 4FO8A 2NQ6A 2BWVA 4R60A 4MATA 2GG8A 2ZSGA 1WKMA 4FUKA 4EGEA 2BB7A 2V3XA 4U1BA 2P99A 1KP0A 3BITA 1WLRA 3L24A 4U75A 2OAZA 4HXXA 2ADUA 4JUQA 2V3YA 3PKAA 3IU8A 4S2TP 2GZ5A 2BWWA 2Q95A 4ZWOA 4IKTA 4RGZ1 4FKCA 5E5BA 4S01A 2BHDA 3TAVA 2B3KA 4IU6A 2IW2A 3L7GA 4QR8A 1YW9A 4U76A 1XGNA 3CTZA 2P98A 1W2MA 2BWXA 1QXWA 4U6CA 2EVCA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2EA4 A;  2NQ7 A;  4PV4 A;  5CNX A;  1C27 A;  3TB5 A;  1R5H A;  3FMR A;  1KQ9 A;  1C24 A;  4U73 A;  2BWY A;  1CHM A;  4IKR A;  1O0X A;  2GG9 A;  1Y1N A;  4U6E A;  4FO7 A;  1MAT A;  3RVA A;  4FLK A;  3PKB A;  4FLL A;  5D6F A;  5CDL A;  3IG4 A;  2B3L A;  2Q8K A;  1M35 A;  1YW7 A;  3PKC A;  4S2R P;  1BOA A;  1QXY A;  2GGC A;  3PKE A;  2Q92 A;  2V6C A;  3ROR A;  2GU7 A;  3MR1 A;  3PKD A;  1N51 A;  3IU9 A;  5D6E A;  5FCH A;  1YJ3 A;  2Q96 A;  2GA2 A;  2GGB A;  4U6J A;  2G6P A;  4FLI A;  1R5G A;  2GU4 A;  3BIP A;  2BHA A;  4U69 A;  1B59 A;  3CB5 A;  1PV9 A;  5FCF A;  1A16 A;  2HOW A;  4PNC A;  2GG7 A;  2GG3 A;  4IDY A;  5JI6 A;  1YW8 A;  2EA2 A;  4KM3 A;  1C22 A;  2BWU A;  3FM3 A;  4ZWP A;  4S00 A;  1XGO A;  1KQ0 A;  2V3Z A;  4U70 A;  1XGM A;  3D27 A;  2BHB A;  4FLJ A;  4U71 A;  2EVO A;  1WN1 A;  1WY2 A;  4Z7M A;  1WL6 A;  4IEC A;  3MX6 A;  5JHU A;  1XGS A;  1WBQ A;  1XNZ A;  2BWS A;  3FMQ A;  4RZY A;  1R58 A;  4A6W A;  5CIK A;  2GG5 A;  2DFI A;  4IF7 A;  2P9A A;  3CB6 A;  2GU6 A;  4U6W A;  4IKU A;  2Q93 A;  5CDE A;  1QZY A;  1B6A A;  2Q94 A;  2GG2 A;  2BHC A;  3BIQ A;  4IPA A;  5CE6 A;  2BWT A;  1C23 A;  5CDV A;  4U6Z A;  5JFR A;  2BN7 A;  4ZNG A;  1W7V A;  3IU7 A;  4OOK A;  2OKN A;  1WL9 A;  1JAW A;  2GG0 A;  2GU5 A;  4ZWU A;  3S6B A;  4A6V A;  2GTX A;  2EVM A;  4IKS A;  2B3H A;  2BH3 A;  5CLS A;  2MAT A;  1YVM A;  1C21 A;  1QXZ A;  1BN5 A;  3Q6D A;  4RZZ A;  4B28 A;  3MAT A;  4FO8 A;  2NQ6 A;  2BWV A;  4R60 A;  4MAT A;  2GG8 A;  2ZSG A;  1WKM A;  4FUK A;  4EGE A;  2BB7 A;  2V3X A;  4U1B A;  2P99 A;  1KP0 A;  3BIT A;  1WLR A;  3L24 A;  4U75 A;  2OAZ A;  4HXX A;  2ADU A;  4JUQ A;  2V3Y A;  3PKA A;  3IU8 A;  4S2T P;  2GZ5 A;  2BWW A;  2Q95 A;  4ZWO A;  4IKT A;  4RGZ 1;  4FKC A;  5E5B A;  4S01 A;  2BHD A;  3TAV A;  2B3K A;  4IU6 A;  2IW2 A;  3L7G A;  4QR8 A;  1YW9 A;  4U76 A;  1XGN A;  3CTZ A;  2P98 A;  1W2M A;  2BWX A;  1QXW A;  4U6C A;  2EVC A; 
#chains in the Genus database with same CATH topology
 2EA4 A;  2NQ7 A;  4PV4 A;  5CNX A;  1C27 A;  3TB5 A;  1R5H A;  3FMR A;  1KQ9 A;  1C24 A;  4U73 A;  2BWY A;  1CHM A;  4IKR A;  1O0X A;  2GG9 A;  1Y1N A;  4U6E A;  4FO7 A;  1MAT A;  3RVA A;  4FLK A;  3PKB A;  4FLL A;  5D6F A;  5CDL A;  3IG4 A;  2B3L A;  2Q8K A;  1M35 A;  1YW7 A;  3PKC A;  4S2R P;  1BOA A;  1QXY A;  2GGC A;  3PKE A;  2Q92 A;  2V6C A;  3ROR A;  2GU7 A;  3MR1 A;  3PKD A;  1N51 A;  3IU9 A;  5D6E A;  5FCH A;  1YJ3 A;  2Q96 A;  2GA2 A;  2GGB A;  4U6J A;  2G6P A;  4FLI A;  1R5G A;  2GU4 A;  3BIP A;  2BHA A;  4U69 A;  1B59 A;  3CB5 A;  1PV9 A;  5FCF A;  1A16 A;  2HOW A;  4PNC A;  2GG7 A;  2GG3 A;  4IDY A;  5JI6 A;  1YW8 A;  2EA2 A;  4KM3 A;  1C22 A;  2BWU A;  3FM3 A;  4ZWP A;  4S00 A;  1XGO A;  1KQ0 A;  2V3Z A;  4U70 A;  1XGM A;  3D27 A;  2BHB A;  4FLJ A;  4U71 A;  2EVO A;  1WN1 A;  1WY2 A;  4Z7M A;  1WL6 A;  4IEC A;  3MX6 A;  5JHU A;  1XGS A;  1WBQ A;  1XNZ A;  2BWS A;  3FMQ A;  4RZY A;  1R58 A;  4A6W A;  5CIK A;  2GG5 A;  2DFI A;  4IF7 A;  2P9A A;  3CB6 A;  2GU6 A;  4U6W A;  4IKU A;  2Q93 A;  5CDE A;  1QZY A;  1B6A A;  2Q94 A;  2GG2 A;  2BHC A;  3BIQ A;  4IPA A;  5CE6 A;  2BWT A;  1C23 A;  5CDV A;  4U6Z A;  5JFR A;  2BN7 A;  4ZNG A;  1W7V A;  3IU7 A;  4OOK A;  2OKN A;  1WL9 A;  1JAW A;  2GG0 A;  2GU5 A;  4ZWU A;  3S6B A;  4A6V A;  2GTX A;  2EVM A;  4IKS A;  2B3H A;  2BH3 A;  5CLS A;  2MAT A;  1YVM A;  1C21 A;  1QXZ A;  1BN5 A;  3Q6D A;  4RZZ A;  4B28 A;  3MAT A;  4FO8 A;  2NQ6 A;  2BWV A;  4R60 A;  4MAT A;  2GG8 A;  2ZSG A;  1WKM A;  4FUK A;  4EGE A;  2BB7 A;  2V3X A;  4U1B A;  2P99 A;  1KP0 A;  3BIT A;  1WLR A;  3L24 A;  4U75 A;  2OAZ A;  4HXX A;  2ADU A;  4JUQ A;  2V3Y A;  3PKA A;  3IU8 A;  4S2T P;  2GZ5 A;  2BWW A;  2Q95 A;  4ZWO A;  4IKT A;  4RGZ 1;  4FKC A;  5E5B A;  4S01 A;  2BHD A;  3TAV A;  2B3K A;  4IU6 A;  2IW2 A;  3L7G A;  4QR8 A;  1YW9 A;  4U76 A;  1XGN A;  3CTZ A;  2P98 A;  1W2M A;  2BWX A;  1QXW A;  4U6C A;  2EVC A; 
#chains in the Genus database with same CATH homology
 2EA4 A;  2NQ7 A;  4PV4 A;  5CNX A;  1C27 A;  3TB5 A;  1R5H A;  3FMR A;  1KQ9 A;  1C24 A;  4U73 A;  2BWY A;  1CHM A;  4IKR A;  1O0X A;  2GG9 A;  1Y1N A;  4U6E A;  4FO7 A;  1MAT A;  3RVA A;  4FLK A;  3PKB A;  4FLL A;  5D6F A;  5CDL A;  3IG4 A;  2B3L A;  2Q8K A;  1M35 A;  1YW7 A;  3PKC A;  4S2R P;  1BOA A;  1QXY A;  2GGC A;  3PKE A;  2Q92 A;  2V6C A;  3ROR A;  2GU7 A;  3MR1 A;  3PKD A;  1N51 A;  3IU9 A;  5D6E A;  5FCH A;  1YJ3 A;  2Q96 A;  2GA2 A;  2GGB A;  4U6J A;  2G6P A;  4FLI A;  1R5G A;  2GU4 A;  3BIP A;  2BHA A;  4U69 A;  1B59 A;  3CB5 A;  1PV9 A;  5FCF A;  1A16 A;  2HOW A;  4PNC A;  2GG7 A;  2GG3 A;  4IDY A;  5JI6 A;  1YW8 A;  2EA2 A;  4KM3 A;  1C22 A;  2BWU A;  3FM3 A;  4ZWP A;  4S00 A;  1XGO A;  1KQ0 A;  2V3Z A;  4U70 A;  1XGM A;  3D27 A;  2BHB A;  4FLJ A;  4U71 A;  2EVO A;  1WN1 A;  1WY2 A;  4Z7M A;  1WL6 A;  4IEC A;  3MX6 A;  5JHU A;  1XGS A;  1WBQ A;  1XNZ A;  2BWS A;  3FMQ A;  4RZY A;  1R58 A;  4A6W A;  5CIK A;  2GG5 A;  2DFI A;  4IF7 A;  2P9A A;  3CB6 A;  2GU6 A;  4U6W A;  4IKU A;  2Q93 A;  5CDE A;  1QZY A;  1B6A A;  2Q94 A;  2GG2 A;  2BHC A;  3BIQ A;  4IPA A;  5CE6 A;  2BWT A;  1C23 A;  5CDV A;  4U6Z A;  5JFR A;  2BN7 A;  4ZNG A;  1W7V A;  3IU7 A;  4OOK A;  2OKN A;  1WL9 A;  1JAW A;  2GG0 A;  2GU5 A;  4ZWU A;  3S6B A;  4A6V A;  2GTX A;  2EVM A;  4IKS A;  2B3H A;  2BH3 A;  5CLS A;  2MAT A;  1YVM A;  1C21 A;  1QXZ A;  1BN5 A;  3Q6D A;  4RZZ A;  4B28 A;  3MAT A;  4FO8 A;  2NQ6 A;  2BWV A;  4R60 A;  4MAT A;  2GG8 A;  2ZSG A;  1WKM A;  4FUK A;  4EGE A;  2BB7 A;  2V3X A;  4U1B A;  2P99 A;  1KP0 A;  3BIT A;  1WLR A;  3L24 A;  4U75 A;  2OAZ A;  4HXX A;  2ADU A;  4JUQ A;  2V3Y A;  3PKA A;  3IU8 A;  4S2T P;  2GZ5 A;  2BWW A;  2Q95 A;  4ZWO A;  4IKT A;  4RGZ 1;  4FKC A;  5E5B A;  4S01 A;  2BHD A;  3TAV A;  2B3K A;  4IU6 A;  2IW2 A;  3L7G A;  4QR8 A;  1YW9 A;  4U76 A;  1XGN A;  3CTZ A;  2P98 A;  1W2M A;  2BWX A;  1QXW A;  4U6C A;  2EVC A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite