3PKEA

M. tuberculosis metap with bengamide analog y10, in ni form
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 88
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkeA01
4FLKA 1C21A 4QR8A 2OKNA 1C23A 2BWWA 4A6WA 4IKSA 3IG4A 4FUKA 1W7VA 3RVAA 2BWXA 2GU5A 2EVMA 4EGEA 1R5GA 3BITA 4IU6A 4FO8A 1YJ3A 4IECA 4U76A 1MATA 3FMQA 3TB5A 3FM3A 2NQ6A 1BOAA 2BWVA 3BIQA 2ADUA 2EA2A 4ZWOA 1QZYA 3PKDA 3Q6DA 1WN1A 4R60A 5JFRA 2BWTA 5CDEA 2GZ5A 4IKRA 1B59A 3MATA 4OOKA 2BHDA 5FCHA 2BWYA 4U75A 4U73A 2GG5A 2V3ZA 2BHCA 4PNCA 2B3HA 5D6FA 5E5BA 2B3KA 2Q93A 2BHBA 4HXXA 4FKCA 2GTXA 1YW7A 1A16A 1W2MA 4ZNGA 1XGNA 4U6EA 4FLJA 4FLIA 5D6EA 1O0XA 2GG0A 4U6CA 1QXZA 2GGCA 2EVCA 2P99A 2V6CA 1WBQA 2GG7A 2P98A 2GU4A 3PKCA 2GU7A 4U1BA 5CNXA 3RORA 2NQ7A 2P9AA 5FCFA 3IU8A 4FO7A 3IU9A 4ZWUA 5CDVA 2GGBA 4JUQA 1R5HA 2V3YA 4IPAA 1JAWA 3CB6A 4Z7MA 4A6VA 4U70A 1XGMA 5CLSA 2BHAA 4ZWPA 1WKMA 4MATA 4RGZ1 1WLRA 1WL6A 4U6ZA 2BWUA 1QXYA 1Y1NA 2IW2A 2ZSGA 4RZZA 1KQ0A 2Q92A 1QXWA 4IDYA 1XGSA 3TAVA 4U6WA 2B3LA 4U69A 1N51A 1XGOA 2EVOA 4S2TP 5JHUA 2GG3A 2MATA 2BWSA 4S01A 2G6PA 1YW8A 3CB5A 3PKAA 4RZYA 1PV9A 4S2RP 4U71A 2GU6A 2V3XA 1WY2A 1KQ9A 5CE6A 2Q96A 1B6AA 3MX6A 2HOWA 4IF7A 2BH3A 3L24A 2BN7A 1BN5A 3L7GA 2Q8KA 3S6BA 2GG2A 5CDLA 1C24A 1C27A 4U6JA 1YW9A 1KP0A 1WL9A 4KM3A 1M35A 4IKUA 1XNZA 4PV4A 2GG8A 3BIPA 3CTZA 3D27A 5CIKA 2OAZA 2GA2A 4FLLA 2EA4A 3PKEA 4IKTA 1CHMA 1YVMA 1C22A 2DFIA 4B28A 3FMRA 3PKBA 3IU7A 2GG9A 3MR1A 1R58A 4S00A 2Q95A 5JI6A 2Q94A 2BB7A
chains in the Genus database with same CATH superfamily
4FLKA 1C21A 4QR8A 2OKNA 1C23A 2BWWA 4A6WA 4IKSA 3IG4A 4FUKA 1W7VA 3RVAA 2BWXA 2GU5A 2EVMA 4EGEA 1R5GA 3BITA 4IU6A 4FO8A 1YJ3A 4IECA 4U76A 1MATA 3FMQA 3TB5A 3FM3A 2NQ6A 1BOAA 2BWVA 3BIQA 2ADUA 2EA2A 4ZWOA 1QZYA 3PKDA 3Q6DA 1WN1A 4R60A 5JFRA 2BWTA 5CDEA 2GZ5A 4IKRA 1B59A 3MATA 4OOKA 2BHDA 5FCHA 2BWYA 4U75A 4U73A 2GG5A 2V3ZA 2BHCA 4PNCA 2B3HA 5D6FA 5E5BA 2B3KA 2Q93A 2BHBA 4HXXA 4FKCA 2GTXA 1YW7A 1A16A 1W2MA 4ZNGA 1XGNA 4U6EA 4FLJA 4FLIA 5D6EA 1O0XA 2GG0A 4U6CA 1QXZA 2GGCA 2EVCA 2P99A 2V6CA 1WBQA 2GG7A 2P98A 2GU4A 3PKCA 2GU7A 4U1BA 5CNXA 3RORA 2NQ7A 2P9AA 5FCFA 3IU8A 4FO7A 3IU9A 4ZWUA 5CDVA 2GGBA 4JUQA 1R5HA 2V3YA 4IPAA 1JAWA 3CB6A 4Z7MA 4A6VA 4U70A 1XGMA 5CLSA 2BHAA 4ZWPA 1WKMA 4MATA 4RGZ1 1WLRA 1WL6A 4U6ZA 2BWUA 1QXYA 1Y1NA 2IW2A 2ZSGA 4RZZA 1KQ0A 2Q92A 1QXWA 4IDYA 1XGSA 3TAVA 4U6WA 2B3LA 4U69A 1N51A 1XGOA 2EVOA 4S2TP 5JHUA 2GG3A 2MATA 2BWSA 4S01A 2G6PA 1YW8A 3CB5A 3PKAA 4RZYA 1PV9A 4S2RP 4U71A 2GU6A 2V3XA 1WY2A 1KQ9A 5CE6A 2Q96A 1B6AA 3MX6A 2HOWA 4IF7A 2BH3A 3L24A 2BN7A 1BN5A 3L7GA 2Q8KA 3S6BA 2GG2A 5CDLA 1C24A 1C27A 4U6JA 1YW9A 1KP0A 1WL9A 4KM3A 1M35A 4IKUA 1XNZA 4PV4A 2GG8A 3BIPA 3CTZA 3D27A 5CIKA 2OAZA 2GA2A 4FLLA 2EA4A 3PKEA 4IKTA 1CHMA 1YVMA 1C22A 2DFIA 4B28A 3FMRA 3PKBA 3IU7A 2GG9A 3MR1A 1R58A 4S00A 2Q95A 5JI6A 2Q94A 2BB7A
chains in the Genus database with same CATH topology
4FLKA 1C21A 4QR8A 2OKNA 1C23A 2BWWA 4A6WA 4IKSA 3IG4A 4FUKA 1W7VA 3RVAA 2BWXA 2GU5A 2EVMA 4EGEA 1R5GA 3BITA 4IU6A 4FO8A 1YJ3A 4IECA 4U76A 1MATA 3FMQA 3TB5A 3FM3A 2NQ6A 1BOAA 2BWVA 3BIQA 2ADUA 2EA2A 4ZWOA 1QZYA 3PKDA 3Q6DA 1WN1A 4R60A 5JFRA 2BWTA 5CDEA 2GZ5A 4IKRA 1B59A 3MATA 4OOKA 2BHDA 5FCHA 2BWYA 4U75A 4U73A 2GG5A 2V3ZA 2BHCA 4PNCA 2B3HA 5D6FA 5E5BA 2B3KA 2Q93A 2BHBA 4HXXA 4FKCA 2GTXA 1YW7A 1A16A 1W2MA 4ZNGA 1XGNA 4U6EA 4FLJA 4FLIA 5D6EA 1O0XA 2GG0A 4U6CA 1QXZA 2GGCA 2EVCA 2P99A 2V6CA 1WBQA 2GG7A 2P98A 2GU4A 3PKCA 2GU7A 4U1BA 5CNXA 3RORA 2NQ7A 2P9AA 5FCFA 3IU8A 4FO7A 3IU9A 4ZWUA 5CDVA 2GGBA 4JUQA 1R5HA 2V3YA 4IPAA 1JAWA 3CB6A 4Z7MA 4A6VA 4U70A 1XGMA 5CLSA 2BHAA 4ZWPA 1WKMA 4MATA 4RGZ1 1WLRA 1WL6A 4U6ZA 2BWUA 1QXYA 1Y1NA 2IW2A 2ZSGA 4RZZA 1KQ0A 2Q92A 1QXWA 4IDYA 1XGSA 3TAVA 4U6WA 2B3LA 4U69A 1N51A 1XGOA 2EVOA 4S2TP 5JHUA 2GG3A 2MATA 2BWSA 4S01A 2G6PA 1YW8A 3CB5A 3PKAA 4RZYA 1PV9A 4S2RP 4U71A 2GU6A 2V3XA 1WY2A 1KQ9A 5CE6A 2Q96A 1B6AA 3MX6A 2HOWA 4IF7A 2BH3A 3L24A 2BN7A 1BN5A 3L7GA 2Q8KA 3S6BA 2GG2A 5CDLA 1C24A 1C27A 4U6JA 1YW9A 1KP0A 1WL9A 4KM3A 1M35A 4IKUA 1XNZA 4PV4A 2GG8A 3BIPA 3CTZA 3D27A 5CIKA 2OAZA 2GA2A 4FLLA 2EA4A 3PKEA 4IKTA 1CHMA 1YVMA 1C22A 2DFIA 4B28A 3FMRA 3PKBA 3IU7A 2GG9A 3MR1A 1R58A 4S00A 2Q95A 5JI6A 2Q94A 2BB7A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4FLK A;  1C21 A;  4QR8 A;  2OKN A;  1C23 A;  2BWW A;  4A6W A;  4IKS A;  3IG4 A;  4FUK A;  1W7V A;  3RVA A;  2BWX A;  2GU5 A;  2EVM A;  4EGE A;  1R5G A;  3BIT A;  4IU6 A;  4FO8 A;  1YJ3 A;  4IEC A;  4U76 A;  1MAT A;  3FMQ A;  3TB5 A;  3FM3 A;  2NQ6 A;  1BOA A;  2BWV A;  3BIQ A;  2ADU A;  2EA2 A;  4ZWO A;  1QZY A;  3PKD A;  3Q6D A;  1WN1 A;  4R60 A;  5JFR A;  2BWT A;  5CDE A;  2GZ5 A;  4IKR A;  1B59 A;  3MAT A;  4OOK A;  2BHD A;  5FCH A;  2BWY A;  4U75 A;  4U73 A;  2GG5 A;  2V3Z A;  2BHC A;  4PNC A;  2B3H A;  5D6F A;  5E5B A;  2B3K A;  2Q93 A;  2BHB A;  4HXX A;  4FKC A;  2GTX A;  1YW7 A;  1A16 A;  1W2M A;  4ZNG A;  1XGN A;  4U6E A;  4FLJ A;  4FLI A;  5D6E A;  1O0X A;  2GG0 A;  4U6C A;  1QXZ A;  2GGC A;  2EVC A;  2P99 A;  2V6C A;  1WBQ A;  2GG7 A;  2P98 A;  2GU4 A;  3PKC A;  2GU7 A;  4U1B A;  5CNX A;  3ROR A;  2NQ7 A;  2P9A A;  5FCF A;  3IU8 A;  4FO7 A;  3IU9 A;  4ZWU A;  5CDV A;  2GGB A;  4JUQ A;  1R5H A;  2V3Y A;  4IPA A;  1JAW A;  3CB6 A;  4Z7M A;  4A6V A;  4U70 A;  1XGM A;  5CLS A;  2BHA A;  4ZWP A;  1WKM A;  4MAT A;  4RGZ 1;  1WLR A;  1WL6 A;  4U6Z A;  2BWU A;  1QXY A;  1Y1N A;  2IW2 A;  2ZSG A;  4RZZ A;  1KQ0 A;  2Q92 A;  1QXW A;  4IDY A;  1XGS A;  3TAV A;  4U6W A;  2B3L A;  4U69 A;  1N51 A;  1XGO A;  2EVO A;  4S2T P;  5JHU A;  2GG3 A;  2MAT A;  2BWS A;  4S01 A;  2G6P A;  1YW8 A;  3CB5 A;  3PKA A;  4RZY A;  1PV9 A;  4S2R P;  4U71 A;  2GU6 A;  2V3X A;  1WY2 A;  1KQ9 A;  5CE6 A;  2Q96 A;  1B6A A;  3MX6 A;  2HOW A;  4IF7 A;  2BH3 A;  3L24 A;  2BN7 A;  1BN5 A;  3L7G A;  2Q8K A;  3S6B A;  2GG2 A;  5CDL A;  1C24 A;  1C27 A;  4U6J A;  1YW9 A;  1KP0 A;  1WL9 A;  4KM3 A;  1M35 A;  4IKU A;  1XNZ A;  4PV4 A;  2GG8 A;  3BIP A;  3CTZ A;  3D27 A;  5CIK A;  2OAZ A;  2GA2 A;  4FLL A;  2EA4 A;  3PKE A;  4IKT A;  1CHM A;  1YVM A;  1C22 A;  2DFI A;  4B28 A;  3FMR A;  3PKB A;  3IU7 A;  2GG9 A;  3MR1 A;  1R58 A;  4S00 A;  2Q95 A;  5JI6 A;  2Q94 A;  2BB7 A; 
#chains in the Genus database with same CATH topology
 4FLK A;  1C21 A;  4QR8 A;  2OKN A;  1C23 A;  2BWW A;  4A6W A;  4IKS A;  3IG4 A;  4FUK A;  1W7V A;  3RVA A;  2BWX A;  2GU5 A;  2EVM A;  4EGE A;  1R5G A;  3BIT A;  4IU6 A;  4FO8 A;  1YJ3 A;  4IEC A;  4U76 A;  1MAT A;  3FMQ A;  3TB5 A;  3FM3 A;  2NQ6 A;  1BOA A;  2BWV A;  3BIQ A;  2ADU A;  2EA2 A;  4ZWO A;  1QZY A;  3PKD A;  3Q6D A;  1WN1 A;  4R60 A;  5JFR A;  2BWT A;  5CDE A;  2GZ5 A;  4IKR A;  1B59 A;  3MAT A;  4OOK A;  2BHD A;  5FCH A;  2BWY A;  4U75 A;  4U73 A;  2GG5 A;  2V3Z A;  2BHC A;  4PNC A;  2B3H A;  5D6F A;  5E5B A;  2B3K A;  2Q93 A;  2BHB A;  4HXX A;  4FKC A;  2GTX A;  1YW7 A;  1A16 A;  1W2M A;  4ZNG A;  1XGN A;  4U6E A;  4FLJ A;  4FLI A;  5D6E A;  1O0X A;  2GG0 A;  4U6C A;  1QXZ A;  2GGC A;  2EVC A;  2P99 A;  2V6C A;  1WBQ A;  2GG7 A;  2P98 A;  2GU4 A;  3PKC A;  2GU7 A;  4U1B A;  5CNX A;  3ROR A;  2NQ7 A;  2P9A A;  5FCF A;  3IU8 A;  4FO7 A;  3IU9 A;  4ZWU A;  5CDV A;  2GGB A;  4JUQ A;  1R5H A;  2V3Y A;  4IPA A;  1JAW A;  3CB6 A;  4Z7M A;  4A6V A;  4U70 A;  1XGM A;  5CLS A;  2BHA A;  4ZWP A;  1WKM A;  4MAT A;  4RGZ 1;  1WLR A;  1WL6 A;  4U6Z A;  2BWU A;  1QXY A;  1Y1N A;  2IW2 A;  2ZSG A;  4RZZ A;  1KQ0 A;  2Q92 A;  1QXW A;  4IDY A;  1XGS A;  3TAV A;  4U6W A;  2B3L A;  4U69 A;  1N51 A;  1XGO A;  2EVO A;  4S2T P;  5JHU A;  2GG3 A;  2MAT A;  2BWS A;  4S01 A;  2G6P A;  1YW8 A;  3CB5 A;  3PKA A;  4RZY A;  1PV9 A;  4S2R P;  4U71 A;  2GU6 A;  2V3X A;  1WY2 A;  1KQ9 A;  5CE6 A;  2Q96 A;  1B6A A;  3MX6 A;  2HOW A;  4IF7 A;  2BH3 A;  3L24 A;  2BN7 A;  1BN5 A;  3L7G A;  2Q8K A;  3S6B A;  2GG2 A;  5CDL A;  1C24 A;  1C27 A;  4U6J A;  1YW9 A;  1KP0 A;  1WL9 A;  4KM3 A;  1M35 A;  4IKU A;  1XNZ A;  4PV4 A;  2GG8 A;  3BIP A;  3CTZ A;  3D27 A;  5CIK A;  2OAZ A;  2GA2 A;  4FLL A;  2EA4 A;  3PKE A;  4IKT A;  1CHM A;  1YVM A;  1C22 A;  2DFI A;  4B28 A;  3FMR A;  3PKB A;  3IU7 A;  2GG9 A;  3MR1 A;  1R58 A;  4S00 A;  2Q95 A;  5JI6 A;  2Q94 A;  2BB7 A; 
#chains in the Genus database with same CATH homology
 4FLK A;  1C21 A;  4QR8 A;  2OKN A;  1C23 A;  2BWW A;  4A6W A;  4IKS A;  3IG4 A;  4FUK A;  1W7V A;  3RVA A;  2BWX A;  2GU5 A;  2EVM A;  4EGE A;  1R5G A;  3BIT A;  4IU6 A;  4FO8 A;  1YJ3 A;  4IEC A;  4U76 A;  1MAT A;  3FMQ A;  3TB5 A;  3FM3 A;  2NQ6 A;  1BOA A;  2BWV A;  3BIQ A;  2ADU A;  2EA2 A;  4ZWO A;  1QZY A;  3PKD A;  3Q6D A;  1WN1 A;  4R60 A;  5JFR A;  2BWT A;  5CDE A;  2GZ5 A;  4IKR A;  1B59 A;  3MAT A;  4OOK A;  2BHD A;  5FCH A;  2BWY A;  4U75 A;  4U73 A;  2GG5 A;  2V3Z A;  2BHC A;  4PNC A;  2B3H A;  5D6F A;  5E5B A;  2B3K A;  2Q93 A;  2BHB A;  4HXX A;  4FKC A;  2GTX A;  1YW7 A;  1A16 A;  1W2M A;  4ZNG A;  1XGN A;  4U6E A;  4FLJ A;  4FLI A;  5D6E A;  1O0X A;  2GG0 A;  4U6C A;  1QXZ A;  2GGC A;  2EVC A;  2P99 A;  2V6C A;  1WBQ A;  2GG7 A;  2P98 A;  2GU4 A;  3PKC A;  2GU7 A;  4U1B A;  5CNX A;  3ROR A;  2NQ7 A;  2P9A A;  5FCF A;  3IU8 A;  4FO7 A;  3IU9 A;  4ZWU A;  5CDV A;  2GGB A;  4JUQ A;  1R5H A;  2V3Y A;  4IPA A;  1JAW A;  3CB6 A;  4Z7M A;  4A6V A;  4U70 A;  1XGM A;  5CLS A;  2BHA A;  4ZWP A;  1WKM A;  4MAT A;  4RGZ 1;  1WLR A;  1WL6 A;  4U6Z A;  2BWU A;  1QXY A;  1Y1N A;  2IW2 A;  2ZSG A;  4RZZ A;  1KQ0 A;  2Q92 A;  1QXW A;  4IDY A;  1XGS A;  3TAV A;  4U6W A;  2B3L A;  4U69 A;  1N51 A;  1XGO A;  2EVO A;  4S2T P;  5JHU A;  2GG3 A;  2MAT A;  2BWS A;  4S01 A;  2G6P A;  1YW8 A;  3CB5 A;  3PKA A;  4RZY A;  1PV9 A;  4S2R P;  4U71 A;  2GU6 A;  2V3X A;  1WY2 A;  1KQ9 A;  5CE6 A;  2Q96 A;  1B6A A;  3MX6 A;  2HOW A;  4IF7 A;  2BH3 A;  3L24 A;  2BN7 A;  1BN5 A;  3L7G A;  2Q8K A;  3S6B A;  2GG2 A;  5CDL A;  1C24 A;  1C27 A;  4U6J A;  1YW9 A;  1KP0 A;  1WL9 A;  4KM3 A;  1M35 A;  4IKU A;  1XNZ A;  4PV4 A;  2GG8 A;  3BIP A;  3CTZ A;  3D27 A;  5CIK A;  2OAZ A;  2GA2 A;  4FLL A;  2EA4 A;  3PKE A;  4IKT A;  1CHM A;  1YVM A;  1C22 A;  2DFI A;  4B28 A;  3FMR A;  3PKB A;  3IU7 A;  2GG9 A;  3MR1 A;  1R58 A;  4S00 A;  2Q95 A;  5JI6 A;  2Q94 A;  2BB7 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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