3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
source organism Mycobacterium tuberculosis
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
4S2RP 3MATA 4EGEA 1M35A 3BIPA 2B3HA 1QXYA 1R58A 2Q95A 2P9AA 2BWVA 4FLKA 3TB5A 3PKEA 5CLSA 2BB7A 3TAVA 1PV9A 3PKCA 4ZWUA 4FLLA 2IW2A 3IU7A 4Z7MA 5CE6A 4QR8A 2V3XA 4ZNGA 1WKMA 1C24A 2BWWA 2MATA 2BHBA 5JFRA 2GA2A 1XNZA 4IKRA 4U69A 1C23A 3PKAA 1O0XA 2GG5A 5CIKA 1YW9A 3PKDA 4KM3A 2Q92A 4U70A 5CDLA 2BHDA 1C27A 2V3YA 2GG2A 1W7VA 1MATA 1WL6A 3CB6A 1WL9A 2GGBA 2B3LA 3RVAA 3S6BA 1C22A 1XGSA 1WY2A 3FM3A 1XGNA 2GU7A 4S00A 2EVCA 1YVMA 4FO7A 2EVMA 4R60A 2GG8A 3MX6A 5CDVA 3CTZA 3PKBA 4U6EA 2BWUA 4U6WA 3Q6DA 4IU6A 4IKSA 1QZYA 2GG3A 1YW7A 1CHMA 2ZSGA 4HXXA 4IKTA 1WBQA 4U1BA 3FMRA 4A6WA 1QXWA 1YJ3A 1BN5A 1KP0A 4RGZ1 2OKNA 2P98A 2GG7A 4FLJA 2NQ7A 4FKCA 5FCFA 2G6PA 2Q96A 4FLIA 2BWXA 2HOWA 3IG4A 3CB5A 2GG0A 1XGMA 1WLRA 3MR1A 2Q93A 1BOAA 4U6JA 2GG9A 2GGCA 3IU9A 2B3KA 2BH3A 4PV4A 4RZYA 5CDEA 2DFIA 3L24A 1W2MA 4OOKA 2Q8KA 2NQ6A 3FMQA 2ADUA 2EVOA 4MATA 1C21A 5JHUA 4PNCA 2BWYA 5E5BA 2GTXA 2BN7A 5D6EA 2GU5A 2GU6A 1XGOA 2BHAA 4IKUA 4U76A 2GZ5A 1YW8A 4A6VA 3BIQA 2BHCA 2V6CA 4U73A 2OAZA 4S2TP 4S01A 4ZWPA 3D27A 5JI6A 1JAWA 1KQ0A 1KQ9A 1WN1A 1R5HA 4U71A 2BWSA 3L7GA 4ZWOA 3BITA 1N51A 3IU8A 1B59A 5CNXA 4IECA 1QXZA 2EA4A 4FUKA 2P99A 4U75A 4RZZA 1R5GA 2EA2A 4IDYA 4IPAA 1A16A 4IF7A 2V3ZA 1Y1NA 4JUQA 4U6CA 4U6ZA 5D6FA 1B6AA 3RORA 4FO8A 2BWTA 5FCHA 2GU4A 4B28A 2Q94A
chains in the Genus database with same CATH superfamily
4S2RP 3MATA 4EGEA 1M35A 3BIPA 2B3HA 1QXYA 1R58A 2Q95A 2P9AA 2BWVA 4FLKA 3TB5A 3PKEA 5CLSA 2BB7A 3TAVA 1PV9A 3PKCA 4ZWUA 4FLLA 2IW2A 3IU7A 4Z7MA 5CE6A 4QR8A 2V3XA 4ZNGA 1WKMA 1C24A 2BWWA 2MATA 2BHBA 5JFRA 2GA2A 1XNZA 4IKRA 4U69A 1C23A 3PKAA 1O0XA 2GG5A 5CIKA 1YW9A 3PKDA 4KM3A 2Q92A 4U70A 5CDLA 2BHDA 1C27A 2V3YA 2GG2A 1W7VA 1MATA 1WL6A 3CB6A 1WL9A 2GGBA 2B3LA 3RVAA 3S6BA 1C22A 1XGSA 1WY2A 3FM3A 1XGNA 2GU7A 4S00A 2EVCA 1YVMA 4FO7A 2EVMA 4R60A 2GG8A 3MX6A 5CDVA 3CTZA 3PKBA 4U6EA 2BWUA 4U6WA 3Q6DA 4IU6A 4IKSA 1QZYA 2GG3A 1YW7A 1CHMA 2ZSGA 4HXXA 4IKTA 1WBQA 4U1BA 3FMRA 4A6WA 1QXWA 1YJ3A 1BN5A 1KP0A 4RGZ1 2OKNA 2P98A 2GG7A 4FLJA 2NQ7A 4FKCA 5FCFA 2G6PA 2Q96A 4FLIA 2BWXA 2HOWA 3IG4A 3CB5A 2GG0A 1XGMA 1WLRA 3MR1A 2Q93A 1BOAA 4U6JA 2GG9A 2GGCA 3IU9A 2B3KA 2BH3A 4PV4A 4RZYA 5CDEA 2DFIA 3L24A 1W2MA 4OOKA 2Q8KA 2NQ6A 3FMQA 2ADUA 2EVOA 4MATA 1C21A 5JHUA 4PNCA 2BWYA 5E5BA 2GTXA 2BN7A 5D6EA 2GU5A 2GU6A 1XGOA 2BHAA 4IKUA 4U76A 2GZ5A 1YW8A 4A6VA 3BIQA 2BHCA 2V6CA 4U73A 2OAZA 4S2TP 4S01A 4ZWPA 3D27A 5JI6A 1JAWA 1KQ0A 1KQ9A 1WN1A 1R5HA 4U71A 2BWSA 3L7GA 4ZWOA 3BITA 1N51A 3IU8A 1B59A 5CNXA 4IECA 1QXZA 2EA4A 4FUKA 2P99A 4U75A 4RZZA 1R5GA 2EA2A 4IDYA 4IPAA 1A16A 4IF7A 2V3ZA 1Y1NA 4JUQA 4U6CA 4U6ZA 5D6FA 1B6AA 3RORA 4FO8A 2BWTA 5FCHA 2GU4A 4B28A 2Q94A
chains in the Genus database with same CATH topology
4S2RP 3MATA 4EGEA 1M35A 3BIPA 2B3HA 1QXYA 1R58A 2Q95A 2P9AA 2BWVA 4FLKA 3TB5A 3PKEA 5CLSA 2BB7A 3TAVA 1PV9A 3PKCA 4ZWUA 4FLLA 2IW2A 3IU7A 4Z7MA 5CE6A 4QR8A 2V3XA 4ZNGA 1WKMA 1C24A 2BWWA 2MATA 2BHBA 5JFRA 2GA2A 1XNZA 4IKRA 4U69A 1C23A 3PKAA 1O0XA 2GG5A 5CIKA 1YW9A 3PKDA 4KM3A 2Q92A 4U70A 5CDLA 2BHDA 1C27A 2V3YA 2GG2A 1W7VA 1MATA 1WL6A 3CB6A 1WL9A 2GGBA 2B3LA 3RVAA 3S6BA 1C22A 1XGSA 1WY2A 3FM3A 1XGNA 2GU7A 4S00A 2EVCA 1YVMA 4FO7A 2EVMA 4R60A 2GG8A 3MX6A 5CDVA 3CTZA 3PKBA 4U6EA 2BWUA 4U6WA 3Q6DA 4IU6A 4IKSA 1QZYA 2GG3A 1YW7A 1CHMA 2ZSGA 4HXXA 4IKTA 1WBQA 4U1BA 3FMRA 4A6WA 1QXWA 1YJ3A 1BN5A 1KP0A 4RGZ1 2OKNA 2P98A 2GG7A 4FLJA 2NQ7A 4FKCA 5FCFA 2G6PA 2Q96A 4FLIA 2BWXA 2HOWA 3IG4A 3CB5A 2GG0A 1XGMA 1WLRA 3MR1A 2Q93A 1BOAA 4U6JA 2GG9A 2GGCA 3IU9A 2B3KA 2BH3A 4PV4A 4RZYA 5CDEA 2DFIA 3L24A 1W2MA 4OOKA 2Q8KA 2NQ6A 3FMQA 2ADUA 2EVOA 4MATA 1C21A 5JHUA 4PNCA 2BWYA 5E5BA 2GTXA 2BN7A 5D6EA 2GU5A 2GU6A 1XGOA 2BHAA 4IKUA 4U76A 2GZ5A 1YW8A 4A6VA 3BIQA 2BHCA 2V6CA 4U73A 2OAZA 4S2TP 4S01A 4ZWPA 3D27A 5JI6A 1JAWA 1KQ0A 1KQ9A 1WN1A 1R5HA 4U71A 2BWSA 3L7GA 4ZWOA 3BITA 1N51A 3IU8A 1B59A 5CNXA 4IECA 1QXZA 2EA4A 4FUKA 2P99A 4U75A 4RZZA 1R5GA 2EA2A 4IDYA 4IPAA 1A16A 4IF7A 2V3ZA 1Y1NA 4JUQA 4U6CA 4U6ZA 5D6FA 1B6AA 3RORA 4FO8A 2BWTA 5FCHA 2GU4A 4B28A 2Q94A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4S2R P;  3MAT A;  4EGE A;  1M35 A;  3BIP A;  2B3H A;  1QXY A;  1R58 A;  2Q95 A;  2P9A A;  2BWV A;  4FLK A;  3TB5 A;  3PKE A;  5CLS A;  2BB7 A;  3TAV A;  1PV9 A;  3PKC A;  4ZWU A;  4FLL A;  2IW2 A;  3IU7 A;  4Z7M A;  5CE6 A;  4QR8 A;  2V3X A;  4ZNG A;  1WKM A;  1C24 A;  2BWW A;  2MAT A;  2BHB A;  5JFR A;  2GA2 A;  1XNZ A;  4IKR A;  4U69 A;  1C23 A;  3PKA A;  1O0X A;  2GG5 A;  5CIK A;  1YW9 A;  3PKD A;  4KM3 A;  2Q92 A;  4U70 A;  5CDL A;  2BHD A;  1C27 A;  2V3Y A;  2GG2 A;  1W7V A;  1MAT A;  1WL6 A;  3CB6 A;  1WL9 A;  2GGB A;  2B3L A;  3RVA A;  3S6B A;  1C22 A;  1XGS A;  1WY2 A;  3FM3 A;  1XGN A;  2GU7 A;  4S00 A;  2EVC A;  1YVM A;  4FO7 A;  2EVM A;  4R60 A;  2GG8 A;  3MX6 A;  5CDV A;  3CTZ A;  3PKB A;  4U6E A;  2BWU A;  4U6W A;  3Q6D A;  4IU6 A;  4IKS A;  1QZY A;  2GG3 A;  1YW7 A;  1CHM A;  2ZSG A;  4HXX A;  4IKT A;  1WBQ A;  4U1B A;  3FMR A;  4A6W A;  1QXW A;  1YJ3 A;  1BN5 A;  1KP0 A;  4RGZ 1;  2OKN A;  2P98 A;  2GG7 A;  4FLJ A;  2NQ7 A;  4FKC A;  5FCF A;  2G6P A;  2Q96 A;  4FLI A;  2BWX A;  2HOW A;  3IG4 A;  3CB5 A;  2GG0 A;  1XGM A;  1WLR A;  3MR1 A;  2Q93 A;  1BOA A;  4U6J A;  2GG9 A;  2GGC A;  3IU9 A;  2B3K A;  2BH3 A;  4PV4 A;  4RZY A;  5CDE A;  2DFI A;  3L24 A;  1W2M A;  4OOK A;  2Q8K A;  2NQ6 A;  3FMQ A;  2ADU A;  2EVO A;  4MAT A;  1C21 A;  5JHU A;  4PNC A;  2BWY A;  5E5B A;  2GTX A;  2BN7 A;  5D6E A;  2GU5 A;  2GU6 A;  1XGO A;  2BHA A;  4IKU A;  4U76 A;  2GZ5 A;  1YW8 A;  4A6V A;  3BIQ A;  2BHC A;  2V6C A;  4U73 A;  2OAZ A;  4S2T P;  4S01 A;  4ZWP A;  3D27 A;  5JI6 A;  1JAW A;  1KQ0 A;  1KQ9 A;  1WN1 A;  1R5H A;  4U71 A;  2BWS A;  3L7G A;  4ZWO A;  3BIT A;  1N51 A;  3IU8 A;  1B59 A;  5CNX A;  4IEC A;  1QXZ A;  2EA4 A;  4FUK A;  2P99 A;  4U75 A;  4RZZ A;  1R5G A;  2EA2 A;  4IDY A;  4IPA A;  1A16 A;  4IF7 A;  2V3Z A;  1Y1N A;  4JUQ A;  4U6C A;  4U6Z A;  5D6F A;  1B6A A;  3ROR A;  4FO8 A;  2BWT A;  5FCH A;  2GU4 A;  4B28 A;  2Q94 A; 
#chains in the Genus database with same CATH topology
 4S2R P;  3MAT A;  4EGE A;  1M35 A;  3BIP A;  2B3H A;  1QXY A;  1R58 A;  2Q95 A;  2P9A A;  2BWV A;  4FLK A;  3TB5 A;  3PKE A;  5CLS A;  2BB7 A;  3TAV A;  1PV9 A;  3PKC A;  4ZWU A;  4FLL A;  2IW2 A;  3IU7 A;  4Z7M A;  5CE6 A;  4QR8 A;  2V3X A;  4ZNG A;  1WKM A;  1C24 A;  2BWW A;  2MAT A;  2BHB A;  5JFR A;  2GA2 A;  1XNZ A;  4IKR A;  4U69 A;  1C23 A;  3PKA A;  1O0X A;  2GG5 A;  5CIK A;  1YW9 A;  3PKD A;  4KM3 A;  2Q92 A;  4U70 A;  5CDL A;  2BHD A;  1C27 A;  2V3Y A;  2GG2 A;  1W7V A;  1MAT A;  1WL6 A;  3CB6 A;  1WL9 A;  2GGB A;  2B3L A;  3RVA A;  3S6B A;  1C22 A;  1XGS A;  1WY2 A;  3FM3 A;  1XGN A;  2GU7 A;  4S00 A;  2EVC A;  1YVM A;  4FO7 A;  2EVM A;  4R60 A;  2GG8 A;  3MX6 A;  5CDV A;  3CTZ A;  3PKB A;  4U6E A;  2BWU A;  4U6W A;  3Q6D A;  4IU6 A;  4IKS A;  1QZY A;  2GG3 A;  1YW7 A;  1CHM A;  2ZSG A;  4HXX A;  4IKT A;  1WBQ A;  4U1B A;  3FMR A;  4A6W A;  1QXW A;  1YJ3 A;  1BN5 A;  1KP0 A;  4RGZ 1;  2OKN A;  2P98 A;  2GG7 A;  4FLJ A;  2NQ7 A;  4FKC A;  5FCF A;  2G6P A;  2Q96 A;  4FLI A;  2BWX A;  2HOW A;  3IG4 A;  3CB5 A;  2GG0 A;  1XGM A;  1WLR A;  3MR1 A;  2Q93 A;  1BOA A;  4U6J A;  2GG9 A;  2GGC A;  3IU9 A;  2B3K A;  2BH3 A;  4PV4 A;  4RZY A;  5CDE A;  2DFI A;  3L24 A;  1W2M A;  4OOK A;  2Q8K A;  2NQ6 A;  3FMQ A;  2ADU A;  2EVO A;  4MAT A;  1C21 A;  5JHU A;  4PNC A;  2BWY A;  5E5B A;  2GTX A;  2BN7 A;  5D6E A;  2GU5 A;  2GU6 A;  1XGO A;  2BHA A;  4IKU A;  4U76 A;  2GZ5 A;  1YW8 A;  4A6V A;  3BIQ A;  2BHC A;  2V6C A;  4U73 A;  2OAZ A;  4S2T P;  4S01 A;  4ZWP A;  3D27 A;  5JI6 A;  1JAW A;  1KQ0 A;  1KQ9 A;  1WN1 A;  1R5H A;  4U71 A;  2BWS A;  3L7G A;  4ZWO A;  3BIT A;  1N51 A;  3IU8 A;  1B59 A;  5CNX A;  4IEC A;  1QXZ A;  2EA4 A;  4FUK A;  2P99 A;  4U75 A;  4RZZ A;  1R5G A;  2EA2 A;  4IDY A;  4IPA A;  1A16 A;  4IF7 A;  2V3Z A;  1Y1N A;  4JUQ A;  4U6C A;  4U6Z A;  5D6F A;  1B6A A;  3ROR A;  4FO8 A;  2BWT A;  5FCH A;  2GU4 A;  4B28 A;  2Q94 A; 
#chains in the Genus database with same CATH homology
 4S2R P;  3MAT A;  4EGE A;  1M35 A;  3BIP A;  2B3H A;  1QXY A;  1R58 A;  2Q95 A;  2P9A A;  2BWV A;  4FLK A;  3TB5 A;  3PKE A;  5CLS A;  2BB7 A;  3TAV A;  1PV9 A;  3PKC A;  4ZWU A;  4FLL A;  2IW2 A;  3IU7 A;  4Z7M A;  5CE6 A;  4QR8 A;  2V3X A;  4ZNG A;  1WKM A;  1C24 A;  2BWW A;  2MAT A;  2BHB A;  5JFR A;  2GA2 A;  1XNZ A;  4IKR A;  4U69 A;  1C23 A;  3PKA A;  1O0X A;  2GG5 A;  5CIK A;  1YW9 A;  3PKD A;  4KM3 A;  2Q92 A;  4U70 A;  5CDL A;  2BHD A;  1C27 A;  2V3Y A;  2GG2 A;  1W7V A;  1MAT A;  1WL6 A;  3CB6 A;  1WL9 A;  2GGB A;  2B3L A;  3RVA A;  3S6B A;  1C22 A;  1XGS A;  1WY2 A;  3FM3 A;  1XGN A;  2GU7 A;  4S00 A;  2EVC A;  1YVM A;  4FO7 A;  2EVM A;  4R60 A;  2GG8 A;  3MX6 A;  5CDV A;  3CTZ A;  3PKB A;  4U6E A;  2BWU A;  4U6W A;  3Q6D A;  4IU6 A;  4IKS A;  1QZY A;  2GG3 A;  1YW7 A;  1CHM A;  2ZSG A;  4HXX A;  4IKT A;  1WBQ A;  4U1B A;  3FMR A;  4A6W A;  1QXW A;  1YJ3 A;  1BN5 A;  1KP0 A;  4RGZ 1;  2OKN A;  2P98 A;  2GG7 A;  4FLJ A;  2NQ7 A;  4FKC A;  5FCF A;  2G6P A;  2Q96 A;  4FLI A;  2BWX A;  2HOW A;  3IG4 A;  3CB5 A;  2GG0 A;  1XGM A;  1WLR A;  3MR1 A;  2Q93 A;  1BOA A;  4U6J A;  2GG9 A;  2GGC A;  3IU9 A;  2B3K A;  2BH3 A;  4PV4 A;  4RZY A;  5CDE A;  2DFI A;  3L24 A;  1W2M A;  4OOK A;  2Q8K A;  2NQ6 A;  3FMQ A;  2ADU A;  2EVO A;  4MAT A;  1C21 A;  5JHU A;  4PNC A;  2BWY A;  5E5B A;  2GTX A;  2BN7 A;  5D6E A;  2GU5 A;  2GU6 A;  1XGO A;  2BHA A;  4IKU A;  4U76 A;  2GZ5 A;  1YW8 A;  4A6V A;  3BIQ A;  2BHC A;  2V6C A;  4U73 A;  2OAZ A;  4S2T P;  4S01 A;  4ZWP A;  3D27 A;  5JI6 A;  1JAW A;  1KQ0 A;  1KQ9 A;  1WN1 A;  1R5H A;  4U71 A;  2BWS A;  3L7G A;  4ZWO A;  3BIT A;  1N51 A;  3IU8 A;  1B59 A;  5CNX A;  4IEC A;  1QXZ A;  2EA4 A;  4FUK A;  2P99 A;  4U75 A;  4RZZ A;  1R5G A;  2EA2 A;  4IDY A;  4IPA A;  1A16 A;  4IF7 A;  2V3Z A;  1Y1N A;  4JUQ A;  4U6C A;  4U6Z A;  5D6F A;  1B6A A;  3ROR A;  4FO8 A;  2BWT A;  5FCH A;  2GU4 A;  4B28 A;  2Q94 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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