4FO8A

Pseudomonas aeruginosa metap with met, in mn form
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
259
Chain Sequence
TVTIKTPDDIEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQKAIPAPLNYKGFPKSICTSINHVVCHGIPNEKPLKEGDILNVDITVIKDGYHGDTSKMFLVGKTPEWADRLCQITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKVFHEEPQVLHYGRAGTGIELKEGMIFTIEPMINQGRPETRLLGDGWTAITKDRKLSAQWEHTVLVTADGYEILTLRNDETFPRTSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Methionine excision captured by the structures of a methionine aminopeptidase
rcsb
source organism Pseudomonas aeruginosa
total genus 83
structure length 259
sequence length 259
chains with identical sequence B, C, D
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4fo8A00
3FMQA 1WL6A 3PKAA 1QZYA 4U75A 1N51A 2EVMA 2GU5A 4IDYA 2BWSA 1XGSA 2BWYA 1WY2A 2EVCA 3IU9A 1WL9A 2Q94A 2OAZA 3RORA 2Q93A 4KM3A 2IW2A 5CLSA 2B3KA 4ZWUA 3RVAA 2GZ5A 1MATA 4QR8A 1JAWA 4A6WA 2ADUA 1W2MA 4PV4A 4OOKA 1WKMA 2BHAA 4U70A 4U76A 3PKDA 2NQ7A 3IU7A 1KP0A 2BB7A 4S00A 5CDVA 2BHDA 2B3HA 4FLLA 5CNXA 2GG3A 2GG2A 4IU6A 1R5GA 1B59A 1C23A 4HXXA 4ZWPA 2GG0A 1BOAA 1XNZA 3MR1A 5D6FA 2DFIA 3CB6A 2GA2A 2V3ZA 1WN1A 1QXWA 1R58A 5JI6A 4FLKA 2B3LA 4IECA 2GG9A 2GG5A 4U6ZA 2P9AA 2GU7A 2BHCA 2V3YA 1O0XA 1PV9A 1XGOA 3IU8A 4U6WA 5CE6A 3PKBA 3IG4A 2BN7A 2GG8A 1C22A 2EA4A 1YW7A 4FKCA 5CIKA 4U1BA 5CDLA 4FO8A 2Q95A 3L7GA 3FMRA 4S01A 2MATA 2BWTA 2V3XA 1R5HA 4FO7A 2ZSGA 2Q8KA 3BIQA 2G6PA 4PNCA 1WBQA 3TAVA 5JHUA 1CHMA 3CTZA 5CDEA 3MX6A 2EVOA 4FUKA 5FCHA 4B28A 4IKUA 4RZYA 3BIPA 4RZZA 3BITA 2BH3A 3MATA 2BHBA 3PKEA 3PKCA 2GGCA 4Z7MA 3L24A 1Y1NA 4FLJA 3FM3A 2P98A 2Q92A 2EA2A 4EGEA 3CB5A 1QXYA 2GU4A 3TB5A 4S2TP 4U6EA 4IKSA 2BWXA 2NQ6A 3S6BA 2BWUA 5JFRA 3D27A 2BWVA 1B6AA 1WLRA 4A6VA 1A16A 4R60A 4U6CA 1XGMA 4ZWOA 1KQ0A 3Q6DA 1YJ3A 1C24A 1YW9A 4MATA 1KQ9A 1BN5A 1C27A 5E5BA 4S2RP 1XGNA 4ZNGA 4U73A 1C21A 2Q96A 2V6CA 1W7VA 2GG7A 4U6JA 1M35A 2OKNA 4FLIA 2GU6A 2BWWA 2HOWA 4U71A 4U69A 1QXZA 2GTXA 4IKRA 4IF7A 4IKTA 5FCFA 4IPAA 1YVMA 1YW8A 2GGBA 5D6EA 2P99A 4RGZ1 4JUQA
chains in the Genus database with same CATH superfamily
3FMQA 1WL6A 3PKAA 1QZYA 4U75A 1N51A 2EVMA 2GU5A 4IDYA 2BWSA 1XGSA 2BWYA 1WY2A 2EVCA 3IU9A 1WL9A 2Q94A 2OAZA 3RORA 2Q93A 4KM3A 2IW2A 5CLSA 2B3KA 4ZWUA 3RVAA 2GZ5A 1MATA 4QR8A 1JAWA 4A6WA 2ADUA 1W2MA 4PV4A 4OOKA 1WKMA 2BHAA 4U70A 4U76A 3PKDA 2NQ7A 3IU7A 1KP0A 2BB7A 4S00A 5CDVA 2BHDA 2B3HA 4FLLA 5CNXA 2GG3A 2GG2A 4IU6A 1R5GA 1B59A 1C23A 4HXXA 4ZWPA 2GG0A 1BOAA 1XNZA 3MR1A 5D6FA 2DFIA 3CB6A 2GA2A 2V3ZA 1WN1A 1QXWA 1R58A 5JI6A 4FLKA 2B3LA 4IECA 2GG9A 2GG5A 4U6ZA 2P9AA 2GU7A 2BHCA 2V3YA 1O0XA 1PV9A 1XGOA 3IU8A 4U6WA 5CE6A 3PKBA 3IG4A 2BN7A 2GG8A 1C22A 2EA4A 1YW7A 4FKCA 5CIKA 4U1BA 5CDLA 4FO8A 2Q95A 3L7GA 3FMRA 4S01A 2MATA 2BWTA 2V3XA 1R5HA 4FO7A 2ZSGA 2Q8KA 3BIQA 2G6PA 4PNCA 1WBQA 3TAVA 5JHUA 1CHMA 3CTZA 5CDEA 3MX6A 2EVOA 4FUKA 5FCHA 4B28A 4IKUA 4RZYA 3BIPA 4RZZA 3BITA 2BH3A 3MATA 2BHBA 3PKEA 3PKCA 2GGCA 4Z7MA 3L24A 1Y1NA 4FLJA 3FM3A 2P98A 2Q92A 2EA2A 4EGEA 3CB5A 1QXYA 2GU4A 3TB5A 4S2TP 4U6EA 4IKSA 2BWXA 2NQ6A 3S6BA 2BWUA 5JFRA 3D27A 2BWVA 1B6AA 1WLRA 4A6VA 1A16A 4R60A 4U6CA 1XGMA 4ZWOA 1KQ0A 3Q6DA 1YJ3A 1C24A 1YW9A 4MATA 1KQ9A 1BN5A 1C27A 5E5BA 4S2RP 1XGNA 4ZNGA 4U73A 1C21A 2Q96A 2V6CA 1W7VA 2GG7A 4U6JA 1M35A 2OKNA 4FLIA 2GU6A 2BWWA 2HOWA 4U71A 4U69A 1QXZA 2GTXA 4IKRA 4IF7A 4IKTA 5FCFA 4IPAA 1YVMA 1YW8A 2GGBA 5D6EA 2P99A 4RGZ1 4JUQA
chains in the Genus database with same CATH topology
3FMQA 1WL6A 3PKAA 1QZYA 4U75A 1N51A 2EVMA 2GU5A 4IDYA 2BWSA 1XGSA 2BWYA 1WY2A 2EVCA 3IU9A 1WL9A 2Q94A 2OAZA 3RORA 2Q93A 4KM3A 2IW2A 5CLSA 2B3KA 4ZWUA 3RVAA 2GZ5A 1MATA 4QR8A 1JAWA 4A6WA 2ADUA 1W2MA 4PV4A 4OOKA 1WKMA 2BHAA 4U70A 4U76A 3PKDA 2NQ7A 3IU7A 1KP0A 2BB7A 4S00A 5CDVA 2BHDA 2B3HA 4FLLA 5CNXA 2GG3A 2GG2A 4IU6A 1R5GA 1B59A 1C23A 4HXXA 4ZWPA 2GG0A 1BOAA 1XNZA 3MR1A 5D6FA 2DFIA 3CB6A 2GA2A 2V3ZA 1WN1A 1QXWA 1R58A 5JI6A 4FLKA 2B3LA 4IECA 2GG9A 2GG5A 4U6ZA 2P9AA 2GU7A 2BHCA 2V3YA 1O0XA 1PV9A 1XGOA 3IU8A 4U6WA 5CE6A 3PKBA 3IG4A 2BN7A 2GG8A 1C22A 2EA4A 1YW7A 4FKCA 5CIKA 4U1BA 5CDLA 4FO8A 2Q95A 3L7GA 3FMRA 4S01A 2MATA 2BWTA 2V3XA 1R5HA 4FO7A 2ZSGA 2Q8KA 3BIQA 2G6PA 4PNCA 1WBQA 3TAVA 5JHUA 1CHMA 3CTZA 5CDEA 3MX6A 2EVOA 4FUKA 5FCHA 4B28A 4IKUA 4RZYA 3BIPA 4RZZA 3BITA 2BH3A 3MATA 2BHBA 3PKEA 3PKCA 2GGCA 4Z7MA 3L24A 1Y1NA 4FLJA 3FM3A 2P98A 2Q92A 2EA2A 4EGEA 3CB5A 1QXYA 2GU4A 3TB5A 4S2TP 4U6EA 4IKSA 2BWXA 2NQ6A 3S6BA 2BWUA 5JFRA 3D27A 2BWVA 1B6AA 1WLRA 4A6VA 1A16A 4R60A 4U6CA 1XGMA 4ZWOA 1KQ0A 3Q6DA 1YJ3A 1C24A 1YW9A 4MATA 1KQ9A 1BN5A 1C27A 5E5BA 4S2RP 1XGNA 4ZNGA 4U73A 1C21A 2Q96A 2V6CA 1W7VA 2GG7A 4U6JA 1M35A 2OKNA 4FLIA 2GU6A 2BWWA 2HOWA 4U71A 4U69A 1QXZA 2GTXA 4IKRA 4IF7A 4IKTA 5FCFA 4IPAA 1YVMA 1YW8A 2GGBA 5D6EA 2P99A 4RGZ1 4JUQA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3FMQ A;  1WL6 A;  3PKA A;  1QZY A;  4U75 A;  1N51 A;  2EVM A;  2GU5 A;  4IDY A;  2BWS A;  1XGS A;  2BWY A;  1WY2 A;  2EVC A;  3IU9 A;  1WL9 A;  2Q94 A;  2OAZ A;  3ROR A;  2Q93 A;  4KM3 A;  2IW2 A;  5CLS A;  2B3K A;  4ZWU A;  3RVA A;  2GZ5 A;  1MAT A;  4QR8 A;  1JAW A;  4A6W A;  2ADU A;  1W2M A;  4PV4 A;  4OOK A;  1WKM A;  2BHA A;  4U70 A;  4U76 A;  3PKD A;  2NQ7 A;  3IU7 A;  1KP0 A;  2BB7 A;  4S00 A;  5CDV A;  2BHD A;  2B3H A;  4FLL A;  5CNX A;  2GG3 A;  2GG2 A;  4IU6 A;  1R5G A;  1B59 A;  1C23 A;  4HXX A;  4ZWP A;  2GG0 A;  1BOA A;  1XNZ A;  3MR1 A;  5D6F A;  2DFI A;  3CB6 A;  2GA2 A;  2V3Z A;  1WN1 A;  1QXW A;  1R58 A;  5JI6 A;  4FLK A;  2B3L A;  4IEC A;  2GG9 A;  2GG5 A;  4U6Z A;  2P9A A;  2GU7 A;  2BHC A;  2V3Y A;  1O0X A;  1PV9 A;  1XGO A;  3IU8 A;  4U6W A;  5CE6 A;  3PKB A;  3IG4 A;  2BN7 A;  2GG8 A;  1C22 A;  2EA4 A;  1YW7 A;  4FKC A;  5CIK A;  4U1B A;  5CDL A;  4FO8 A;  2Q95 A;  3L7G A;  3FMR A;  4S01 A;  2MAT A;  2BWT A;  2V3X A;  1R5H A;  4FO7 A;  2ZSG A;  2Q8K A;  3BIQ A;  2G6P A;  4PNC A;  1WBQ A;  3TAV A;  5JHU A;  1CHM A;  3CTZ A;  5CDE A;  3MX6 A;  2EVO A;  4FUK A;  5FCH A;  4B28 A;  4IKU A;  4RZY A;  3BIP A;  4RZZ A;  3BIT A;  2BH3 A;  3MAT A;  2BHB A;  3PKE A;  3PKC A;  2GGC A;  4Z7M A;  3L24 A;  1Y1N A;  4FLJ A;  3FM3 A;  2P98 A;  2Q92 A;  2EA2 A;  4EGE A;  3CB5 A;  1QXY A;  2GU4 A;  3TB5 A;  4S2T P;  4U6E A;  4IKS A;  2BWX A;  2NQ6 A;  3S6B A;  2BWU A;  5JFR A;  3D27 A;  2BWV A;  1B6A A;  1WLR A;  4A6V A;  1A16 A;  4R60 A;  4U6C A;  1XGM A;  4ZWO A;  1KQ0 A;  3Q6D A;  1YJ3 A;  1C24 A;  1YW9 A;  4MAT A;  1KQ9 A;  1BN5 A;  1C27 A;  5E5B A;  4S2R P;  1XGN A;  4ZNG A;  4U73 A;  1C21 A;  2Q96 A;  2V6C A;  1W7V A;  2GG7 A;  4U6J A;  1M35 A;  2OKN A;  4FLI A;  2GU6 A;  2BWW A;  2HOW A;  4U71 A;  4U69 A;  1QXZ A;  2GTX A;  4IKR A;  4IF7 A;  4IKT A;  5FCF A;  4IPA A;  1YVM A;  1YW8 A;  2GGB A;  5D6E A;  2P99 A;  4RGZ 1;  4JUQ A; 
#chains in the Genus database with same CATH topology
 3FMQ A;  1WL6 A;  3PKA A;  1QZY A;  4U75 A;  1N51 A;  2EVM A;  2GU5 A;  4IDY A;  2BWS A;  1XGS A;  2BWY A;  1WY2 A;  2EVC A;  3IU9 A;  1WL9 A;  2Q94 A;  2OAZ A;  3ROR A;  2Q93 A;  4KM3 A;  2IW2 A;  5CLS A;  2B3K A;  4ZWU A;  3RVA A;  2GZ5 A;  1MAT A;  4QR8 A;  1JAW A;  4A6W A;  2ADU A;  1W2M A;  4PV4 A;  4OOK A;  1WKM A;  2BHA A;  4U70 A;  4U76 A;  3PKD A;  2NQ7 A;  3IU7 A;  1KP0 A;  2BB7 A;  4S00 A;  5CDV A;  2BHD A;  2B3H A;  4FLL A;  5CNX A;  2GG3 A;  2GG2 A;  4IU6 A;  1R5G A;  1B59 A;  1C23 A;  4HXX A;  4ZWP A;  2GG0 A;  1BOA A;  1XNZ A;  3MR1 A;  5D6F A;  2DFI A;  3CB6 A;  2GA2 A;  2V3Z A;  1WN1 A;  1QXW A;  1R58 A;  5JI6 A;  4FLK A;  2B3L A;  4IEC A;  2GG9 A;  2GG5 A;  4U6Z A;  2P9A A;  2GU7 A;  2BHC A;  2V3Y A;  1O0X A;  1PV9 A;  1XGO A;  3IU8 A;  4U6W A;  5CE6 A;  3PKB A;  3IG4 A;  2BN7 A;  2GG8 A;  1C22 A;  2EA4 A;  1YW7 A;  4FKC A;  5CIK A;  4U1B A;  5CDL A;  4FO8 A;  2Q95 A;  3L7G A;  3FMR A;  4S01 A;  2MAT A;  2BWT A;  2V3X A;  1R5H A;  4FO7 A;  2ZSG A;  2Q8K A;  3BIQ A;  2G6P A;  4PNC A;  1WBQ A;  3TAV A;  5JHU A;  1CHM A;  3CTZ A;  5CDE A;  3MX6 A;  2EVO A;  4FUK A;  5FCH A;  4B28 A;  4IKU A;  4RZY A;  3BIP A;  4RZZ A;  3BIT A;  2BH3 A;  3MAT A;  2BHB A;  3PKE A;  3PKC A;  2GGC A;  4Z7M A;  3L24 A;  1Y1N A;  4FLJ A;  3FM3 A;  2P98 A;  2Q92 A;  2EA2 A;  4EGE A;  3CB5 A;  1QXY A;  2GU4 A;  3TB5 A;  4S2T P;  4U6E A;  4IKS A;  2BWX A;  2NQ6 A;  3S6B A;  2BWU A;  5JFR A;  3D27 A;  2BWV A;  1B6A A;  1WLR A;  4A6V A;  1A16 A;  4R60 A;  4U6C A;  1XGM A;  4ZWO A;  1KQ0 A;  3Q6D A;  1YJ3 A;  1C24 A;  1YW9 A;  4MAT A;  1KQ9 A;  1BN5 A;  1C27 A;  5E5B A;  4S2R P;  1XGN A;  4ZNG A;  4U73 A;  1C21 A;  2Q96 A;  2V6C A;  1W7V A;  2GG7 A;  4U6J A;  1M35 A;  2OKN A;  4FLI A;  2GU6 A;  2BWW A;  2HOW A;  4U71 A;  4U69 A;  1QXZ A;  2GTX A;  4IKR A;  4IF7 A;  4IKT A;  5FCF A;  4IPA A;  1YVM A;  1YW8 A;  2GGB A;  5D6E A;  2P99 A;  4RGZ 1;  4JUQ A; 
#chains in the Genus database with same CATH homology
 3FMQ A;  1WL6 A;  3PKA A;  1QZY A;  4U75 A;  1N51 A;  2EVM A;  2GU5 A;  4IDY A;  2BWS A;  1XGS A;  2BWY A;  1WY2 A;  2EVC A;  3IU9 A;  1WL9 A;  2Q94 A;  2OAZ A;  3ROR A;  2Q93 A;  4KM3 A;  2IW2 A;  5CLS A;  2B3K A;  4ZWU A;  3RVA A;  2GZ5 A;  1MAT A;  4QR8 A;  1JAW A;  4A6W A;  2ADU A;  1W2M A;  4PV4 A;  4OOK A;  1WKM A;  2BHA A;  4U70 A;  4U76 A;  3PKD A;  2NQ7 A;  3IU7 A;  1KP0 A;  2BB7 A;  4S00 A;  5CDV A;  2BHD A;  2B3H A;  4FLL A;  5CNX A;  2GG3 A;  2GG2 A;  4IU6 A;  1R5G A;  1B59 A;  1C23 A;  4HXX A;  4ZWP A;  2GG0 A;  1BOA A;  1XNZ A;  3MR1 A;  5D6F A;  2DFI A;  3CB6 A;  2GA2 A;  2V3Z A;  1WN1 A;  1QXW A;  1R58 A;  5JI6 A;  4FLK A;  2B3L A;  4IEC A;  2GG9 A;  2GG5 A;  4U6Z A;  2P9A A;  2GU7 A;  2BHC A;  2V3Y A;  1O0X A;  1PV9 A;  1XGO A;  3IU8 A;  4U6W A;  5CE6 A;  3PKB A;  3IG4 A;  2BN7 A;  2GG8 A;  1C22 A;  2EA4 A;  1YW7 A;  4FKC A;  5CIK A;  4U1B A;  5CDL A;  4FO8 A;  2Q95 A;  3L7G A;  3FMR A;  4S01 A;  2MAT A;  2BWT A;  2V3X A;  1R5H A;  4FO7 A;  2ZSG A;  2Q8K A;  3BIQ A;  2G6P A;  4PNC A;  1WBQ A;  3TAV A;  5JHU A;  1CHM A;  3CTZ A;  5CDE A;  3MX6 A;  2EVO A;  4FUK A;  5FCH A;  4B28 A;  4IKU A;  4RZY A;  3BIP A;  4RZZ A;  3BIT A;  2BH3 A;  3MAT A;  2BHB A;  3PKE A;  3PKC A;  2GGC A;  4Z7M A;  3L24 A;  1Y1N A;  4FLJ A;  3FM3 A;  2P98 A;  2Q92 A;  2EA2 A;  4EGE A;  3CB5 A;  1QXY A;  2GU4 A;  3TB5 A;  4S2T P;  4U6E A;  4IKS A;  2BWX A;  2NQ6 A;  3S6B A;  2BWU A;  5JFR A;  3D27 A;  2BWV A;  1B6A A;  1WLR A;  4A6V A;  1A16 A;  4R60 A;  4U6C A;  1XGM A;  4ZWO A;  1KQ0 A;  3Q6D A;  1YJ3 A;  1C24 A;  1YW9 A;  4MAT A;  1KQ9 A;  1BN5 A;  1C27 A;  5E5B A;  4S2R P;  1XGN A;  4ZNG A;  4U73 A;  1C21 A;  2Q96 A;  2V6C A;  1W7V A;  2GG7 A;  4U6J A;  1M35 A;  2OKN A;  4FLI A;  2GU6 A;  2BWW A;  2HOW A;  4U71 A;  4U69 A;  1QXZ A;  2GTX A;  4IKR A;  4IF7 A;  4IKT A;  5FCF A;  4IPA A;  1YVM A;  1YW8 A;  2GGB A;  5D6E A;  2P99 A;  4RGZ 1;  4JUQ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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