4FUKA

Aminopeptidase from trypanosoma brucei
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
336
structure length
329
Chain Sequence
AMKTFDFTGPLRPGKITPRRAVPSHILRPDYADRAGGVSASEEKDRGSKVKVYNIQFLHDDSKAEIQRIKTVCQLSREVLDIATAAAKPGITTDELDRIVHEATVERNMYPSPLNYYGFPKSVCTSVNEVICHGIPDSRELEEGDILNIDVSSYLNGFHGDLNETVFIGRPDDDSVRLVHAAYECLCAGIGVVKPEALYKQVGDAIEACASQYQCSVVRTYTGHGVGHLFHTSPTVCHYANLGMMRPGHVFTIEPMINLGTWQDVTWPDKWTSTTKDGRRSAQFEHTMVVTNGGVEIFTDWVDGVPTYQKQLKEWGIMLPQRKESATAV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Aminpeptidase from Trypanosoma brucei (CASP Target)
rcsb
source organism Trypanosoma brucei brucei
total genus 105
structure length 329
sequence length 336
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4fukA01
3PKEA 3D27A 4IPAA 2EA2A 4U73A 1O0XA 1XGSA 3IU9A 2Q8KA 2EVCA 4B28A 2GG7A 4U71A 5CIKA 4U6JA 2BWYA 1QXZA 2GG3A 2B3KA 2GU4A 2P98A 3FMRA 4U6WA 3PKDA 4FLIA 4ZNGA 4U1BA 4FLJA 4EGEA 4PNCA 1WBQA 4U6EA 1YW8A 3BITA 4IU6A 2GU5A 4IKUA 4U6ZA 2BWSA 4FUKA 4ZWPA 4OOKA 1WL6A 3PKCA 2BHCA 1R58A 1C23A 4IECA 1WN1A 4U70A 3TB5A 3PKBA 4MATA 1XNZA 2BWTA 1QZYA 2V3ZA 2V3XA 1YW7A 2DFIA 1XGMA 5CNXA 2Q96A 3FMQA 2GU7A 1KP0A 1QXYA 4IDYA 3S6BA 1B59A 2GG9A 4PV4A 1CHMA 3Q6DA 4S00A 1M35A 2GG0A 1YJ3A 2NQ6A 4ZWUA 2GGBA 2P99A 3MATA 2G6PA 1A16A 1BN5A 2GG8A 2GGCA 2BHAA 2Q94A 5CDVA 2BWVA 3L7GA 4FKCA 4RZYA 5CE6A 2HOWA 2BWWA 2GG2A 3IU7A 1R5GA 5D6EA 2ADUA 4IKSA 4IKTA 4U6CA 3CTZA 4RGZ1 3BIPA 4FLLA 3RVAA 2NQ7A 4FO7A 5FCFA 1QXWA 1R5HA 2BB7A 3MX6A 4ZWOA 1B6AA 2GU6A 1KQ9A 3RORA 2MATA 2GZ5A 1YVMA 2GG5A 5CLSA 1C24A 4A6VA 3L24A 4RZZA 2EA4A 2GTXA 3MR1A 2Q93A 2OKNA 2ZSGA 4Z7MA 1N51A 2EVOA 3CB6A 5JI6A 2Q92A 3IG4A 2BWUA 4S2RP 1W2MA 2EVMA 1MATA 2Q95A 4A6WA 1W7VA 2V6CA 3IU8A 4FLKA 1WLRA 3FM3A 1YW9A 1WKMA 4JUQA 1C21A 2B3LA 5D6FA 4S01A 4S2TP 1C22A 2IW2A 5CDLA 4U69A 2BH3A 4IKRA 3PKAA 4R60A 2P9AA 4QR8A 5CDEA 1WL9A 4U75A 1WY2A 1XGOA 1Y1NA 3CB5A 2BHDA 3BIQA 3TAVA 4HXXA 2OAZA 1XGNA 5FCHA 1BOAA 5JFRA 4FO8A 5JHUA 2B3HA 1PV9A 2V3YA 2BN7A 4IF7A 2GA2A 5E5BA 2BWXA 2BHBA 4U76A 4KM3A 1KQ0A 1C27A 1JAWA
chains in the Genus database with same CATH superfamily
3PKEA 3D27A 4IPAA 2EA2A 4U73A 1O0XA 1XGSA 3IU9A 2Q8KA 2EVCA 4B28A 2GG7A 4U71A 5CIKA 4U6JA 2BWYA 1QXZA 2GG3A 2B3KA 2GU4A 2P98A 3FMRA 4U6WA 3PKDA 4FLIA 4ZNGA 4U1BA 4FLJA 4EGEA 4PNCA 1WBQA 4U6EA 1YW8A 3BITA 4IU6A 2GU5A 4IKUA 4U6ZA 2BWSA 4FUKA 4ZWPA 4OOKA 1WL6A 3PKCA 2BHCA 1R58A 1C23A 4IECA 1WN1A 4U70A 3TB5A 3PKBA 4MATA 1XNZA 2BWTA 1QZYA 2V3ZA 2V3XA 1YW7A 2DFIA 1XGMA 5CNXA 2Q96A 3FMQA 2GU7A 1KP0A 1QXYA 4IDYA 3S6BA 1B59A 2GG9A 4PV4A 1CHMA 3Q6DA 4S00A 1M35A 2GG0A 1YJ3A 2NQ6A 4ZWUA 2GGBA 2P99A 3MATA 2G6PA 1A16A 1BN5A 2GG8A 2GGCA 2BHAA 2Q94A 5CDVA 2BWVA 3L7GA 4FKCA 4RZYA 5CE6A 2HOWA 2BWWA 2GG2A 3IU7A 1R5GA 5D6EA 2ADUA 4IKSA 4IKTA 4U6CA 3CTZA 4RGZ1 3BIPA 4FLLA 3RVAA 2NQ7A 4FO7A 5FCFA 1QXWA 1R5HA 2BB7A 3MX6A 4ZWOA 1B6AA 2GU6A 1KQ9A 3RORA 2MATA 2GZ5A 1YVMA 2GG5A 5CLSA 1C24A 4A6VA 3L24A 4RZZA 2EA4A 2GTXA 3MR1A 2Q93A 2OKNA 2ZSGA 4Z7MA 1N51A 2EVOA 3CB6A 5JI6A 2Q92A 3IG4A 2BWUA 4S2RP 1W2MA 2EVMA 1MATA 2Q95A 4A6WA 1W7VA 2V6CA 3IU8A 4FLKA 1WLRA 3FM3A 1YW9A 1WKMA 4JUQA 1C21A 2B3LA 5D6FA 4S01A 4S2TP 1C22A 2IW2A 5CDLA 4U69A 2BH3A 4IKRA 3PKAA 4R60A 2P9AA 4QR8A 5CDEA 1WL9A 4U75A 1WY2A 1XGOA 1Y1NA 3CB5A 2BHDA 3BIQA 3TAVA 4HXXA 2OAZA 1XGNA 5FCHA 1BOAA 5JFRA 4FO8A 5JHUA 2B3HA 1PV9A 2V3YA 2BN7A 4IF7A 2GA2A 5E5BA 2BWXA 2BHBA 4U76A 4KM3A 1KQ0A 1C27A 1JAWA
chains in the Genus database with same CATH topology
3PKEA 3D27A 4IPAA 2EA2A 4U73A 1O0XA 1XGSA 3IU9A 2Q8KA 2EVCA 4B28A 2GG7A 4U71A 5CIKA 4U6JA 2BWYA 1QXZA 2GG3A 2B3KA 2GU4A 2P98A 3FMRA 4U6WA 3PKDA 4FLIA 4ZNGA 4U1BA 4FLJA 4EGEA 4PNCA 1WBQA 4U6EA 1YW8A 3BITA 4IU6A 2GU5A 4IKUA 4U6ZA 2BWSA 4FUKA 4ZWPA 4OOKA 1WL6A 3PKCA 2BHCA 1R58A 1C23A 4IECA 1WN1A 4U70A 3TB5A 3PKBA 4MATA 1XNZA 2BWTA 1QZYA 2V3ZA 2V3XA 1YW7A 2DFIA 1XGMA 5CNXA 2Q96A 3FMQA 2GU7A 1KP0A 1QXYA 4IDYA 3S6BA 1B59A 2GG9A 4PV4A 1CHMA 3Q6DA 4S00A 1M35A 2GG0A 1YJ3A 2NQ6A 4ZWUA 2GGBA 2P99A 3MATA 2G6PA 1A16A 1BN5A 2GG8A 2GGCA 2BHAA 2Q94A 5CDVA 2BWVA 3L7GA 4FKCA 4RZYA 5CE6A 2HOWA 2BWWA 2GG2A 3IU7A 1R5GA 5D6EA 2ADUA 4IKSA 4IKTA 4U6CA 3CTZA 4RGZ1 3BIPA 4FLLA 3RVAA 2NQ7A 4FO7A 5FCFA 1QXWA 1R5HA 2BB7A 3MX6A 4ZWOA 1B6AA 2GU6A 1KQ9A 3RORA 2MATA 2GZ5A 1YVMA 2GG5A 5CLSA 1C24A 4A6VA 3L24A 4RZZA 2EA4A 2GTXA 3MR1A 2Q93A 2OKNA 2ZSGA 4Z7MA 1N51A 2EVOA 3CB6A 5JI6A 2Q92A 3IG4A 2BWUA 4S2RP 1W2MA 2EVMA 1MATA 2Q95A 4A6WA 1W7VA 2V6CA 3IU8A 4FLKA 1WLRA 3FM3A 1YW9A 1WKMA 4JUQA 1C21A 2B3LA 5D6FA 4S01A 4S2TP 1C22A 2IW2A 5CDLA 4U69A 2BH3A 4IKRA 3PKAA 4R60A 2P9AA 4QR8A 5CDEA 1WL9A 4U75A 1WY2A 1XGOA 1Y1NA 3CB5A 2BHDA 3BIQA 3TAVA 4HXXA 2OAZA 1XGNA 5FCHA 1BOAA 5JFRA 4FO8A 5JHUA 2B3HA 1PV9A 2V3YA 2BN7A 4IF7A 2GA2A 5E5BA 2BWXA 2BHBA 4U76A 4KM3A 1KQ0A 1C27A 1JAWA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3PKE A;  3D27 A;  4IPA A;  2EA2 A;  4U73 A;  1O0X A;  1XGS A;  3IU9 A;  2Q8K A;  2EVC A;  4B28 A;  2GG7 A;  4U71 A;  5CIK A;  4U6J A;  2BWY A;  1QXZ A;  2GG3 A;  2B3K A;  2GU4 A;  2P98 A;  3FMR A;  4U6W A;  3PKD A;  4FLI A;  4ZNG A;  4U1B A;  4FLJ A;  4EGE A;  4PNC A;  1WBQ A;  4U6E A;  1YW8 A;  3BIT A;  4IU6 A;  2GU5 A;  4IKU A;  4U6Z A;  2BWS A;  4FUK A;  4ZWP A;  4OOK A;  1WL6 A;  3PKC A;  2BHC A;  1R58 A;  1C23 A;  4IEC A;  1WN1 A;  4U70 A;  3TB5 A;  3PKB A;  4MAT A;  1XNZ A;  2BWT A;  1QZY A;  2V3Z A;  2V3X A;  1YW7 A;  2DFI A;  1XGM A;  5CNX A;  2Q96 A;  3FMQ A;  2GU7 A;  1KP0 A;  1QXY A;  4IDY A;  3S6B A;  1B59 A;  2GG9 A;  4PV4 A;  1CHM A;  3Q6D A;  4S00 A;  1M35 A;  2GG0 A;  1YJ3 A;  2NQ6 A;  4ZWU A;  2GGB A;  2P99 A;  3MAT A;  2G6P A;  1A16 A;  1BN5 A;  2GG8 A;  2GGC A;  2BHA A;  2Q94 A;  5CDV A;  2BWV A;  3L7G A;  4FKC A;  4RZY A;  5CE6 A;  2HOW A;  2BWW A;  2GG2 A;  3IU7 A;  1R5G A;  5D6E A;  2ADU A;  4IKS A;  4IKT A;  4U6C A;  3CTZ A;  4RGZ 1;  3BIP A;  4FLL A;  3RVA A;  2NQ7 A;  4FO7 A;  5FCF A;  1QXW A;  1R5H A;  2BB7 A;  3MX6 A;  4ZWO A;  1B6A A;  2GU6 A;  1KQ9 A;  3ROR A;  2MAT A;  2GZ5 A;  1YVM A;  2GG5 A;  5CLS A;  1C24 A;  4A6V A;  3L24 A;  4RZZ A;  2EA4 A;  2GTX A;  3MR1 A;  2Q93 A;  2OKN A;  2ZSG A;  4Z7M A;  1N51 A;  2EVO A;  3CB6 A;  5JI6 A;  2Q92 A;  3IG4 A;  2BWU A;  4S2R P;  1W2M A;  2EVM A;  1MAT A;  2Q95 A;  4A6W A;  1W7V A;  2V6C A;  3IU8 A;  4FLK A;  1WLR A;  3FM3 A;  1YW9 A;  1WKM A;  4JUQ A;  1C21 A;  2B3L A;  5D6F A;  4S01 A;  4S2T P;  1C22 A;  2IW2 A;  5CDL A;  4U69 A;  2BH3 A;  4IKR A;  3PKA A;  4R60 A;  2P9A A;  4QR8 A;  5CDE A;  1WL9 A;  4U75 A;  1WY2 A;  1XGO A;  1Y1N A;  3CB5 A;  2BHD A;  3BIQ A;  3TAV A;  4HXX A;  2OAZ A;  1XGN A;  5FCH A;  1BOA A;  5JFR A;  4FO8 A;  5JHU A;  2B3H A;  1PV9 A;  2V3Y A;  2BN7 A;  4IF7 A;  2GA2 A;  5E5B A;  2BWX A;  2BHB A;  4U76 A;  4KM3 A;  1KQ0 A;  1C27 A;  1JAW A; 
#chains in the Genus database with same CATH topology
 3PKE A;  3D27 A;  4IPA A;  2EA2 A;  4U73 A;  1O0X A;  1XGS A;  3IU9 A;  2Q8K A;  2EVC A;  4B28 A;  2GG7 A;  4U71 A;  5CIK A;  4U6J A;  2BWY A;  1QXZ A;  2GG3 A;  2B3K A;  2GU4 A;  2P98 A;  3FMR A;  4U6W A;  3PKD A;  4FLI A;  4ZNG A;  4U1B A;  4FLJ A;  4EGE A;  4PNC A;  1WBQ A;  4U6E A;  1YW8 A;  3BIT A;  4IU6 A;  2GU5 A;  4IKU A;  4U6Z A;  2BWS A;  4FUK A;  4ZWP A;  4OOK A;  1WL6 A;  3PKC A;  2BHC A;  1R58 A;  1C23 A;  4IEC A;  1WN1 A;  4U70 A;  3TB5 A;  3PKB A;  4MAT A;  1XNZ A;  2BWT A;  1QZY A;  2V3Z A;  2V3X A;  1YW7 A;  2DFI A;  1XGM A;  5CNX A;  2Q96 A;  3FMQ A;  2GU7 A;  1KP0 A;  1QXY A;  4IDY A;  3S6B A;  1B59 A;  2GG9 A;  4PV4 A;  1CHM A;  3Q6D A;  4S00 A;  1M35 A;  2GG0 A;  1YJ3 A;  2NQ6 A;  4ZWU A;  2GGB A;  2P99 A;  3MAT A;  2G6P A;  1A16 A;  1BN5 A;  2GG8 A;  2GGC A;  2BHA A;  2Q94 A;  5CDV A;  2BWV A;  3L7G A;  4FKC A;  4RZY A;  5CE6 A;  2HOW A;  2BWW A;  2GG2 A;  3IU7 A;  1R5G A;  5D6E A;  2ADU A;  4IKS A;  4IKT A;  4U6C A;  3CTZ A;  4RGZ 1;  3BIP A;  4FLL A;  3RVA A;  2NQ7 A;  4FO7 A;  5FCF A;  1QXW A;  1R5H A;  2BB7 A;  3MX6 A;  4ZWO A;  1B6A A;  2GU6 A;  1KQ9 A;  3ROR A;  2MAT A;  2GZ5 A;  1YVM A;  2GG5 A;  5CLS A;  1C24 A;  4A6V A;  3L24 A;  4RZZ A;  2EA4 A;  2GTX A;  3MR1 A;  2Q93 A;  2OKN A;  2ZSG A;  4Z7M A;  1N51 A;  2EVO A;  3CB6 A;  5JI6 A;  2Q92 A;  3IG4 A;  2BWU A;  4S2R P;  1W2M A;  2EVM A;  1MAT A;  2Q95 A;  4A6W A;  1W7V A;  2V6C A;  3IU8 A;  4FLK A;  1WLR A;  3FM3 A;  1YW9 A;  1WKM A;  4JUQ A;  1C21 A;  2B3L A;  5D6F A;  4S01 A;  4S2T P;  1C22 A;  2IW2 A;  5CDL A;  4U69 A;  2BH3 A;  4IKR A;  3PKA A;  4R60 A;  2P9A A;  4QR8 A;  5CDE A;  1WL9 A;  4U75 A;  1WY2 A;  1XGO A;  1Y1N A;  3CB5 A;  2BHD A;  3BIQ A;  3TAV A;  4HXX A;  2OAZ A;  1XGN A;  5FCH A;  1BOA A;  5JFR A;  4FO8 A;  5JHU A;  2B3H A;  1PV9 A;  2V3Y A;  2BN7 A;  4IF7 A;  2GA2 A;  5E5B A;  2BWX A;  2BHB A;  4U76 A;  4KM3 A;  1KQ0 A;  1C27 A;  1JAW A; 
#chains in the Genus database with same CATH homology
 3PKE A;  3D27 A;  4IPA A;  2EA2 A;  4U73 A;  1O0X A;  1XGS A;  3IU9 A;  2Q8K A;  2EVC A;  4B28 A;  2GG7 A;  4U71 A;  5CIK A;  4U6J A;  2BWY A;  1QXZ A;  2GG3 A;  2B3K A;  2GU4 A;  2P98 A;  3FMR A;  4U6W A;  3PKD A;  4FLI A;  4ZNG A;  4U1B A;  4FLJ A;  4EGE A;  4PNC A;  1WBQ A;  4U6E A;  1YW8 A;  3BIT A;  4IU6 A;  2GU5 A;  4IKU A;  4U6Z A;  2BWS A;  4FUK A;  4ZWP A;  4OOK A;  1WL6 A;  3PKC A;  2BHC A;  1R58 A;  1C23 A;  4IEC A;  1WN1 A;  4U70 A;  3TB5 A;  3PKB A;  4MAT A;  1XNZ A;  2BWT A;  1QZY A;  2V3Z A;  2V3X A;  1YW7 A;  2DFI A;  1XGM A;  5CNX A;  2Q96 A;  3FMQ A;  2GU7 A;  1KP0 A;  1QXY A;  4IDY A;  3S6B A;  1B59 A;  2GG9 A;  4PV4 A;  1CHM A;  3Q6D A;  4S00 A;  1M35 A;  2GG0 A;  1YJ3 A;  2NQ6 A;  4ZWU A;  2GGB A;  2P99 A;  3MAT A;  2G6P A;  1A16 A;  1BN5 A;  2GG8 A;  2GGC A;  2BHA A;  2Q94 A;  5CDV A;  2BWV A;  3L7G A;  4FKC A;  4RZY A;  5CE6 A;  2HOW A;  2BWW A;  2GG2 A;  3IU7 A;  1R5G A;  5D6E A;  2ADU A;  4IKS A;  4IKT A;  4U6C A;  3CTZ A;  4RGZ 1;  3BIP A;  4FLL A;  3RVA A;  2NQ7 A;  4FO7 A;  5FCF A;  1QXW A;  1R5H A;  2BB7 A;  3MX6 A;  4ZWO A;  1B6A A;  2GU6 A;  1KQ9 A;  3ROR A;  2MAT A;  2GZ5 A;  1YVM A;  2GG5 A;  5CLS A;  1C24 A;  4A6V A;  3L24 A;  4RZZ A;  2EA4 A;  2GTX A;  3MR1 A;  2Q93 A;  2OKN A;  2ZSG A;  4Z7M A;  1N51 A;  2EVO A;  3CB6 A;  5JI6 A;  2Q92 A;  3IG4 A;  2BWU A;  4S2R P;  1W2M A;  2EVM A;  1MAT A;  2Q95 A;  4A6W A;  1W7V A;  2V6C A;  3IU8 A;  4FLK A;  1WLR A;  3FM3 A;  1YW9 A;  1WKM A;  4JUQ A;  1C21 A;  2B3L A;  5D6F A;  4S01 A;  4S2T P;  1C22 A;  2IW2 A;  5CDL A;  4U69 A;  2BH3 A;  4IKR A;  3PKA A;  4R60 A;  2P9A A;  4QR8 A;  5CDE A;  1WL9 A;  4U75 A;  1WY2 A;  1XGO A;  1Y1N A;  3CB5 A;  2BHD A;  3BIQ A;  3TAV A;  4HXX A;  2OAZ A;  1XGN A;  5FCH A;  1BOA A;  5JFR A;  4FO8 A;  5JHU A;  2B3H A;  1PV9 A;  2V3Y A;  2BN7 A;  4IF7 A;  2GA2 A;  5E5B A;  2BWX A;  2BHB A;  4U76 A;  4KM3 A;  1KQ0 A;  1C27 A;  1JAW A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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