4MATA

E.coli methionine aminopeptidase his79ala mutant
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
271
structure length
271
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDELVPRGSLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords PROTEIN (METHIONINE AMINOPEPTIDASE)
publication title Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
pubmed doi rcsb
source organism Escherichia coli
total genus 89
structure length 271
sequence length 271
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4matA00
2Q96A 1B6AA 1WN1A 4U6CA 2BHDA 4FLIA 1XGOA 2BWTA 2BHBA 2V3YA 3IU7A 5JFRA 1W7VA 1YJ3A 3PKCA 4IDYA 2GGBA 4ZWUA 4U69A 5CDVA 3FMRA 4IECA 1CHMA 2EVMA 2BN7A 2GG7A 3L24A 4KM3A 2GU6A 4S01A 4U75A 4B28A 4U73A 2GG0A 3RORA 4FO8A 2HOWA 4U71A 2BWSA 2GG3A 2GU7A 2V6CA 2BWYA 5FCHA 2BWXA 2B3KA 4R60A 4IKTA 3TAVA 2GZ5A 4IU6A 2GU4A 4U6WA 1C21A 4U6ZA 1XGSA 2P99A 1BN5A 3BIPA 4FO7A 2GG9A 2BHAA 2B3LA 3IG4A 1WKMA 2B3HA 3RVAA 1XGMA 1PV9A 4RGZ1 2P9AA 5E5BA 2ADUA 3IU8A 4RZYA 5CE6A 5JI6A 2NQ7A 3FMQA 2Q8KA 1KP0A 4S2TP 1A16A 1WL9A 2BWUA 2BB7A 4FLLA 4S2RP 5CLSA 4A6VA 1R5HA 3PKEA 4IKSA 3IU9A 2GA2A 2EA2A 3MR1A 3S6BA 4RZZA 1O0XA 1WLRA 3MX6A 3BITA 2G6PA 1WBQA 1QZYA 2P98A 5D6EA 3CTZA 3CB6A 4FLKA 2OAZA 4IPAA 4U6JA 5D6FA 4IF7A 1R5GA 1YW7A 2GG8A 5CNXA 1BOAA 5CDLA 2EVOA 2DFIA 2Q95A 4FUKA 4JUQA 3TB5A 1C27A 2GG2A 3MATA 3FM3A 4QR8A 4U6EA 5CDEA 4A6WA 2V3ZA 1M35A 1XGNA 3PKDA 2OKNA 2GU5A 4IKUA 1QXYA 2BHCA 4PNCA 1YW8A 1C24A 4ZWOA 4EGEA 2EA4A 1QXZA 1WY2A 5JHUA 1JAWA 4U1BA 2BH3A 2MATA 4FKCA 1W2MA 1N51A 3L7GA 4OOKA 1B59A 3D27A 4HXXA 3BIQA 4FLJA 4IKRA 1MATA 1KQ9A 2GTXA 5FCFA 1XNZA 4Z7MA 1YW9A 2GGCA 3CB5A 1C23A 1KQ0A 2V3XA 4PV4A 4U70A 1C22A 1WL6A 3PKAA 2Q93A 4U76A 1YVMA 3PKBA 4S00A 1R58A 2Q94A 2Q92A 1QXWA 2NQ6A 3Q6DA 4ZWPA 2BWVA 2BWWA 2GG5A 2IW2A 2EVCA 5CIKA 4MATA 2ZSGA 1Y1NA 4ZNGA
chains in the Genus database with same CATH superfamily
2Q96A 1B6AA 1WN1A 4U6CA 2BHDA 4FLIA 1XGOA 2BWTA 2BHBA 2V3YA 3IU7A 5JFRA 1W7VA 1YJ3A 3PKCA 4IDYA 2GGBA 4ZWUA 4U69A 5CDVA 3FMRA 4IECA 1CHMA 2EVMA 2BN7A 2GG7A 3L24A 4KM3A 2GU6A 4S01A 4U75A 4B28A 4U73A 2GG0A 3RORA 4FO8A 2HOWA 4U71A 2BWSA 2GG3A 2GU7A 2V6CA 2BWYA 5FCHA 2BWXA 2B3KA 4R60A 4IKTA 3TAVA 2GZ5A 4IU6A 2GU4A 4U6WA 1C21A 4U6ZA 1XGSA 2P99A 1BN5A 3BIPA 4FO7A 2GG9A 2BHAA 2B3LA 3IG4A 1WKMA 2B3HA 3RVAA 1XGMA 1PV9A 4RGZ1 2P9AA 5E5BA 2ADUA 3IU8A 4RZYA 5CE6A 5JI6A 2NQ7A 3FMQA 2Q8KA 1KP0A 4S2TP 1A16A 1WL9A 2BWUA 2BB7A 4FLLA 4S2RP 5CLSA 4A6VA 1R5HA 3PKEA 4IKSA 3IU9A 2GA2A 2EA2A 3MR1A 3S6BA 4RZZA 1O0XA 1WLRA 3MX6A 3BITA 2G6PA 1WBQA 1QZYA 2P98A 5D6EA 3CTZA 3CB6A 4FLKA 2OAZA 4IPAA 4U6JA 5D6FA 4IF7A 1R5GA 1YW7A 2GG8A 5CNXA 1BOAA 5CDLA 2EVOA 2DFIA 2Q95A 4FUKA 4JUQA 3TB5A 1C27A 2GG2A 3MATA 3FM3A 4QR8A 4U6EA 5CDEA 4A6WA 2V3ZA 1M35A 1XGNA 3PKDA 2OKNA 2GU5A 4IKUA 1QXYA 2BHCA 4PNCA 1YW8A 1C24A 4ZWOA 4EGEA 2EA4A 1QXZA 1WY2A 5JHUA 1JAWA 4U1BA 2BH3A 2MATA 4FKCA 1W2MA 1N51A 3L7GA 4OOKA 1B59A 3D27A 4HXXA 3BIQA 4FLJA 4IKRA 1MATA 1KQ9A 2GTXA 5FCFA 1XNZA 4Z7MA 1YW9A 2GGCA 3CB5A 1C23A 1KQ0A 2V3XA 4PV4A 4U70A 1C22A 1WL6A 3PKAA 2Q93A 4U76A 1YVMA 3PKBA 4S00A 1R58A 2Q94A 2Q92A 1QXWA 2NQ6A 3Q6DA 4ZWPA 2BWVA 2BWWA 2GG5A 2IW2A 2EVCA 5CIKA 4MATA 2ZSGA 1Y1NA 4ZNGA
chains in the Genus database with same CATH topology
2Q96A 1B6AA 1WN1A 4U6CA 2BHDA 4FLIA 1XGOA 2BWTA 2BHBA 2V3YA 3IU7A 5JFRA 1W7VA 1YJ3A 3PKCA 4IDYA 2GGBA 4ZWUA 4U69A 5CDVA 3FMRA 4IECA 1CHMA 2EVMA 2BN7A 2GG7A 3L24A 4KM3A 2GU6A 4S01A 4U75A 4B28A 4U73A 2GG0A 3RORA 4FO8A 2HOWA 4U71A 2BWSA 2GG3A 2GU7A 2V6CA 2BWYA 5FCHA 2BWXA 2B3KA 4R60A 4IKTA 3TAVA 2GZ5A 4IU6A 2GU4A 4U6WA 1C21A 4U6ZA 1XGSA 2P99A 1BN5A 3BIPA 4FO7A 2GG9A 2BHAA 2B3LA 3IG4A 1WKMA 2B3HA 3RVAA 1XGMA 1PV9A 4RGZ1 2P9AA 5E5BA 2ADUA 3IU8A 4RZYA 5CE6A 5JI6A 2NQ7A 3FMQA 2Q8KA 1KP0A 4S2TP 1A16A 1WL9A 2BWUA 2BB7A 4FLLA 4S2RP 5CLSA 4A6VA 1R5HA 3PKEA 4IKSA 3IU9A 2GA2A 2EA2A 3MR1A 3S6BA 4RZZA 1O0XA 1WLRA 3MX6A 3BITA 2G6PA 1WBQA 1QZYA 2P98A 5D6EA 3CTZA 3CB6A 4FLKA 2OAZA 4IPAA 4U6JA 5D6FA 4IF7A 1R5GA 1YW7A 2GG8A 5CNXA 1BOAA 5CDLA 2EVOA 2DFIA 2Q95A 4FUKA 4JUQA 3TB5A 1C27A 2GG2A 3MATA 3FM3A 4QR8A 4U6EA 5CDEA 4A6WA 2V3ZA 1M35A 1XGNA 3PKDA 2OKNA 2GU5A 4IKUA 1QXYA 2BHCA 4PNCA 1YW8A 1C24A 4ZWOA 4EGEA 2EA4A 1QXZA 1WY2A 5JHUA 1JAWA 4U1BA 2BH3A 2MATA 4FKCA 1W2MA 1N51A 3L7GA 4OOKA 1B59A 3D27A 4HXXA 3BIQA 4FLJA 4IKRA 1MATA 1KQ9A 2GTXA 5FCFA 1XNZA 4Z7MA 1YW9A 2GGCA 3CB5A 1C23A 1KQ0A 2V3XA 4PV4A 4U70A 1C22A 1WL6A 3PKAA 2Q93A 4U76A 1YVMA 3PKBA 4S00A 1R58A 2Q94A 2Q92A 1QXWA 2NQ6A 3Q6DA 4ZWPA 2BWVA 2BWWA 2GG5A 2IW2A 2EVCA 5CIKA 4MATA 2ZSGA 1Y1NA 4ZNGA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2Q96 A;  1B6A A;  1WN1 A;  4U6C A;  2BHD A;  4FLI A;  1XGO A;  2BWT A;  2BHB A;  2V3Y A;  3IU7 A;  5JFR A;  1W7V A;  1YJ3 A;  3PKC A;  4IDY A;  2GGB A;  4ZWU A;  4U69 A;  5CDV A;  3FMR A;  4IEC A;  1CHM A;  2EVM A;  2BN7 A;  2GG7 A;  3L24 A;  4KM3 A;  2GU6 A;  4S01 A;  4U75 A;  4B28 A;  4U73 A;  2GG0 A;  3ROR A;  4FO8 A;  2HOW A;  4U71 A;  2BWS A;  2GG3 A;  2GU7 A;  2V6C A;  2BWY A;  5FCH A;  2BWX A;  2B3K A;  4R60 A;  4IKT A;  3TAV A;  2GZ5 A;  4IU6 A;  2GU4 A;  4U6W A;  1C21 A;  4U6Z A;  1XGS A;  2P99 A;  1BN5 A;  3BIP A;  4FO7 A;  2GG9 A;  2BHA A;  2B3L A;  3IG4 A;  1WKM A;  2B3H A;  3RVA A;  1XGM A;  1PV9 A;  4RGZ 1;  2P9A A;  5E5B A;  2ADU A;  3IU8 A;  4RZY A;  5CE6 A;  5JI6 A;  2NQ7 A;  3FMQ A;  2Q8K A;  1KP0 A;  4S2T P;  1A16 A;  1WL9 A;  2BWU A;  2BB7 A;  4FLL A;  4S2R P;  5CLS A;  4A6V A;  1R5H A;  3PKE A;  4IKS A;  3IU9 A;  2GA2 A;  2EA2 A;  3MR1 A;  3S6B A;  4RZZ A;  1O0X A;  1WLR A;  3MX6 A;  3BIT A;  2G6P A;  1WBQ A;  1QZY A;  2P98 A;  5D6E A;  3CTZ A;  3CB6 A;  4FLK A;  2OAZ A;  4IPA A;  4U6J A;  5D6F A;  4IF7 A;  1R5G A;  1YW7 A;  2GG8 A;  5CNX A;  1BOA A;  5CDL A;  2EVO A;  2DFI A;  2Q95 A;  4FUK A;  4JUQ A;  3TB5 A;  1C27 A;  2GG2 A;  3MAT A;  3FM3 A;  4QR8 A;  4U6E A;  5CDE A;  4A6W A;  2V3Z A;  1M35 A;  1XGN A;  3PKD A;  2OKN A;  2GU5 A;  4IKU A;  1QXY A;  2BHC A;  4PNC A;  1YW8 A;  1C24 A;  4ZWO A;  4EGE A;  2EA4 A;  1QXZ A;  1WY2 A;  5JHU A;  1JAW A;  4U1B A;  2BH3 A;  2MAT A;  4FKC A;  1W2M A;  1N51 A;  3L7G A;  4OOK A;  1B59 A;  3D27 A;  4HXX A;  3BIQ A;  4FLJ A;  4IKR A;  1MAT A;  1KQ9 A;  2GTX A;  5FCF A;  1XNZ A;  4Z7M A;  1YW9 A;  2GGC A;  3CB5 A;  1C23 A;  1KQ0 A;  2V3X A;  4PV4 A;  4U70 A;  1C22 A;  1WL6 A;  3PKA A;  2Q93 A;  4U76 A;  1YVM A;  3PKB A;  4S00 A;  1R58 A;  2Q94 A;  2Q92 A;  1QXW A;  2NQ6 A;  3Q6D A;  4ZWP A;  2BWV A;  2BWW A;  2GG5 A;  2IW2 A;  2EVC A;  5CIK A;  4MAT A;  2ZSG A;  1Y1N A;  4ZNG A; 
#chains in the Genus database with same CATH topology
 2Q96 A;  1B6A A;  1WN1 A;  4U6C A;  2BHD A;  4FLI A;  1XGO A;  2BWT A;  2BHB A;  2V3Y A;  3IU7 A;  5JFR A;  1W7V A;  1YJ3 A;  3PKC A;  4IDY A;  2GGB A;  4ZWU A;  4U69 A;  5CDV A;  3FMR A;  4IEC A;  1CHM A;  2EVM A;  2BN7 A;  2GG7 A;  3L24 A;  4KM3 A;  2GU6 A;  4S01 A;  4U75 A;  4B28 A;  4U73 A;  2GG0 A;  3ROR A;  4FO8 A;  2HOW A;  4U71 A;  2BWS A;  2GG3 A;  2GU7 A;  2V6C A;  2BWY A;  5FCH A;  2BWX A;  2B3K A;  4R60 A;  4IKT A;  3TAV A;  2GZ5 A;  4IU6 A;  2GU4 A;  4U6W A;  1C21 A;  4U6Z A;  1XGS A;  2P99 A;  1BN5 A;  3BIP A;  4FO7 A;  2GG9 A;  2BHA A;  2B3L A;  3IG4 A;  1WKM A;  2B3H A;  3RVA A;  1XGM A;  1PV9 A;  4RGZ 1;  2P9A A;  5E5B A;  2ADU A;  3IU8 A;  4RZY A;  5CE6 A;  5JI6 A;  2NQ7 A;  3FMQ A;  2Q8K A;  1KP0 A;  4S2T P;  1A16 A;  1WL9 A;  2BWU A;  2BB7 A;  4FLL A;  4S2R P;  5CLS A;  4A6V A;  1R5H A;  3PKE A;  4IKS A;  3IU9 A;  2GA2 A;  2EA2 A;  3MR1 A;  3S6B A;  4RZZ A;  1O0X A;  1WLR A;  3MX6 A;  3BIT A;  2G6P A;  1WBQ A;  1QZY A;  2P98 A;  5D6E A;  3CTZ A;  3CB6 A;  4FLK A;  2OAZ A;  4IPA A;  4U6J A;  5D6F A;  4IF7 A;  1R5G A;  1YW7 A;  2GG8 A;  5CNX A;  1BOA A;  5CDL A;  2EVO A;  2DFI A;  2Q95 A;  4FUK A;  4JUQ A;  3TB5 A;  1C27 A;  2GG2 A;  3MAT A;  3FM3 A;  4QR8 A;  4U6E A;  5CDE A;  4A6W A;  2V3Z A;  1M35 A;  1XGN A;  3PKD A;  2OKN A;  2GU5 A;  4IKU A;  1QXY A;  2BHC A;  4PNC A;  1YW8 A;  1C24 A;  4ZWO A;  4EGE A;  2EA4 A;  1QXZ A;  1WY2 A;  5JHU A;  1JAW A;  4U1B A;  2BH3 A;  2MAT A;  4FKC A;  1W2M A;  1N51 A;  3L7G A;  4OOK A;  1B59 A;  3D27 A;  4HXX A;  3BIQ A;  4FLJ A;  4IKR A;  1MAT A;  1KQ9 A;  2GTX A;  5FCF A;  1XNZ A;  4Z7M A;  1YW9 A;  2GGC A;  3CB5 A;  1C23 A;  1KQ0 A;  2V3X A;  4PV4 A;  4U70 A;  1C22 A;  1WL6 A;  3PKA A;  2Q93 A;  4U76 A;  1YVM A;  3PKB A;  4S00 A;  1R58 A;  2Q94 A;  2Q92 A;  1QXW A;  2NQ6 A;  3Q6D A;  4ZWP A;  2BWV A;  2BWW A;  2GG5 A;  2IW2 A;  2EVC A;  5CIK A;  4MAT A;  2ZSG A;  1Y1N A;  4ZNG A; 
#chains in the Genus database with same CATH homology
 2Q96 A;  1B6A A;  1WN1 A;  4U6C A;  2BHD A;  4FLI A;  1XGO A;  2BWT A;  2BHB A;  2V3Y A;  3IU7 A;  5JFR A;  1W7V A;  1YJ3 A;  3PKC A;  4IDY A;  2GGB A;  4ZWU A;  4U69 A;  5CDV A;  3FMR A;  4IEC A;  1CHM A;  2EVM A;  2BN7 A;  2GG7 A;  3L24 A;  4KM3 A;  2GU6 A;  4S01 A;  4U75 A;  4B28 A;  4U73 A;  2GG0 A;  3ROR A;  4FO8 A;  2HOW A;  4U71 A;  2BWS A;  2GG3 A;  2GU7 A;  2V6C A;  2BWY A;  5FCH A;  2BWX A;  2B3K A;  4R60 A;  4IKT A;  3TAV A;  2GZ5 A;  4IU6 A;  2GU4 A;  4U6W A;  1C21 A;  4U6Z A;  1XGS A;  2P99 A;  1BN5 A;  3BIP A;  4FO7 A;  2GG9 A;  2BHA A;  2B3L A;  3IG4 A;  1WKM A;  2B3H A;  3RVA A;  1XGM A;  1PV9 A;  4RGZ 1;  2P9A A;  5E5B A;  2ADU A;  3IU8 A;  4RZY A;  5CE6 A;  5JI6 A;  2NQ7 A;  3FMQ A;  2Q8K A;  1KP0 A;  4S2T P;  1A16 A;  1WL9 A;  2BWU A;  2BB7 A;  4FLL A;  4S2R P;  5CLS A;  4A6V A;  1R5H A;  3PKE A;  4IKS A;  3IU9 A;  2GA2 A;  2EA2 A;  3MR1 A;  3S6B A;  4RZZ A;  1O0X A;  1WLR A;  3MX6 A;  3BIT A;  2G6P A;  1WBQ A;  1QZY A;  2P98 A;  5D6E A;  3CTZ A;  3CB6 A;  4FLK A;  2OAZ A;  4IPA A;  4U6J A;  5D6F A;  4IF7 A;  1R5G A;  1YW7 A;  2GG8 A;  5CNX A;  1BOA A;  5CDL A;  2EVO A;  2DFI A;  2Q95 A;  4FUK A;  4JUQ A;  3TB5 A;  1C27 A;  2GG2 A;  3MAT A;  3FM3 A;  4QR8 A;  4U6E A;  5CDE A;  4A6W A;  2V3Z A;  1M35 A;  1XGN A;  3PKD A;  2OKN A;  2GU5 A;  4IKU A;  1QXY A;  2BHC A;  4PNC A;  1YW8 A;  1C24 A;  4ZWO A;  4EGE A;  2EA4 A;  1QXZ A;  1WY2 A;  5JHU A;  1JAW A;  4U1B A;  2BH3 A;  2MAT A;  4FKC A;  1W2M A;  1N51 A;  3L7G A;  4OOK A;  1B59 A;  3D27 A;  4HXX A;  3BIQ A;  4FLJ A;  4IKR A;  1MAT A;  1KQ9 A;  2GTX A;  5FCF A;  1XNZ A;  4Z7M A;  1YW9 A;  2GGC A;  3CB5 A;  1C23 A;  1KQ0 A;  2V3X A;  4PV4 A;  4U70 A;  1C22 A;  1WL6 A;  3PKA A;  2Q93 A;  4U76 A;  1YVM A;  3PKB A;  4S00 A;  1R58 A;  2Q94 A;  2Q92 A;  1QXW A;  2NQ6 A;  3Q6D A;  4ZWP A;  2BWV A;  2BWW A;  2GG5 A;  2IW2 A;  2EVC A;  5CIK A;  4MAT A;  2ZSG A;  1Y1N A;  4ZNG A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite