1J8EA

Crystal structure of ligand-binding repeat cr7 from lrp
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
44
structure length
44
Chain Sequence
GSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
pubmed doi rcsb
molecule keywords LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1
total genus 14
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2001-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00057 Ldl_recept_a Low-density lipoprotein receptor domain class A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.400.10 Few Secondary Structures Irregular Low-density Lipoprotein Receptor Low-density Lipoprotein Receptor 1j8eA00
1CR8A 2KNXA 1LDRA 1XFEA 2M96A 2M0PA 1J8EA 2FYJA 1D2LA 2KNYA 1D2JA 1K7BA 1N7DA 2I1PA 1F5YA 2FCWB 1LDLA 2LGPA 1JRFA 2FYLB 2JM4A 2M7PA
chains in the Genus database with same CATH superfamily
1CR8A 2KNXA 1LDRA 1XFEA 2M96A 2M0PA 1J8EA 2FYJA 1D2LA 2KNYA 1D2JA 1K7BA 1N7DA 2I1PA 1F5YA 2FCWB 1LDLA 2LGPA 1JRFA 2FYLB 2JM4A 2M7PA
chains in the Genus database with same CATH topology
1CR8A 2KNXA 1LDRA 1XFEA 2M96A 2M0PA 1J8EA 2FYJA 1D2LA 2KNYA 1D2JA 1K7BA 1N7DA 2I1PA 1F5YA 2FCWB 1LDLA 2LGPA 1JRFA 2FYLB 2JM4A 2M7PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CR8 A;  2KNX A;  1LDR A;  1XFE A;  2M96 A;  2M0P A;  1J8E A;  2FYJ A;  1D2L A;  2KNY A;  1D2J A;  1K7B A;  1N7D A;  2I1P A;  1F5Y A;  2FCW B;  1LDL A;  2LGP A;  1JRF A;  2FYL B;  2JM4 A;  2M7P A; 
#chains in the Genus database with same CATH topology
 1CR8 A;  2KNX A;  1LDR A;  1XFE A;  2M96 A;  2M0P A;  1J8E A;  2FYJ A;  1D2L A;  2KNY A;  1D2J A;  1K7B A;  1N7D A;  2I1P A;  1F5Y A;  2FCW B;  1LDL A;  2LGP A;  1JRF A;  2FYL B;  2JM4 A;  2M7P A; 
#chains in the Genus database with same CATH homology
 1CR8 A;  2KNX A;  1LDR A;  1XFE A;  2M96 A;  2M0P A;  1J8E A;  2FYJ A;  1D2L A;  2KNY A;  1D2J A;  1K7B A;  1N7D A;  2I1P A;  1F5Y A;  2FCW B;  1LDL A;  2LGP A;  1JRF A;  2FYL B;  2JM4 A;  2M7P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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