1KACA

Knob domain from adenovirus serotype 12 in complex with domain 1 of its cellular receptor car
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
185
structure length
185
Chain Sequence
TPYDPLTLWTTPDPPPNCSLIQELDAKLTLCLTKNGSIVNGIVSLVGVKGNLLNIQSTTTTVGVHLVFDEQGRLITSTPTALVPQASWGYRQGQSVSTNTVTNGLGFMPNVSAYPRPNASEAKSQMVSLTYLQGDTSKPITMKVAFNGITSLNGYSLTFMWSGLSNYINQPFSTPSCSFSYITQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.
pubmed doi rcsb
molecule tags Viral protein/receptor
source organism Human adenovirus 12
molecule keywords PROTEIN (FIBER KNOB PROTEIN)
total genus 37
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 1999-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 1kacA00
4K6UA 2WBWA 1UXBA 3F0YA 1QIUA 1UXEA 4XL8A 2WGUA 2W9LC 1P69A 2WSTA 1KNBA 2O39A 3EXWA 3EXVA 1H7ZA 2QLKA 2WBVA 2J2JA 1KACA 4XQAA 2WGTA 4WYJA 3CNCA 4K6VA 1P6AA 3O8EA 1QHVA 4K6WA 4LIYA 1UXAA 2BZVA 3QNDA 4XQBA 3L88A 4ZDGA 4ATZA 3L89A 4K6TA 2J1KC 1NOBA 2BZUA 3BQ4A 2J12A 3N0IA
chains in the Genus database with same CATH superfamily
4K6UA 2WBWA 1UXBA 3F0YA 5MHSA 1QIUA 1UXEA 4XL8A 4GU3A 2IUNA 2WGUA 2W9LC 2BT7A 1P69A 2WSTA 4D62A 1KNBA 2O39A 3EXWA 2OJ5A 4XC5A 3EXVA 1H7ZA 1KKEA 2BT8A 2QLKA 2VTWA 2WBVA 4CW8A 2J2JA 4D63A 1KACA 2JJLA 4XQAA 2WGTA 4WYJA 3CNCA 4K6VA 1P6AA 3O8EA 1QHVA 4K6WA 4LIYA 2OJ6A 2VRSA 3EOYA 3ZPEA 1UXAA 2BSFA 2BZVA 3QNDA 4XQBA 3ZPFA 3L88A 4ODBA 4ZDGA 4ATZA 3L89A 3S6XA 2IUMA 4K6TA 2J1KC 1NOBA 2BZUA 3BQ4A 2J12A 4GU4A 3N0IA
chains in the Genus database with same CATH topology
4K6UA 2WBWA 1UXBA 3F0YA 1QIUA 1UXEA 4XL8A 2WGUA 2W9LC 1P69A 2WSTA 1KNBA 2O39A 3EXWA 3EXVA 1H7ZA 2QLKA 2WBVA 2J2JA 1KACA 4XQAA 2WGTA 4WYJA 3CNCA 4K6VA 1P6AA 3O8EA 1QHVA 4K6WA 4LIYA 1UXAA 2BZVA 3QNDA 4XQBA 3L88A 4ZDGA 4ATZA 3L89A 4K6TA 2J1KC 1NOBA 2BZUA 3BQ4A 2J12A 3N0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K6U A;  2WBW A;  1UXB A;  3F0Y A;  1QIU A;  1UXE A;  4XL8 A;  2WGU A;  2W9L C;  1P69 A;  2WST A;  1KNB A;  2O39 A;  3EXW A;  3EXV A;  1H7Z A;  2QLK A;  2WBV A;  2J2J A;  1KAC A;  4XQA A;  2WGT A;  4WYJ A;  3CNC A;  4K6V A;  1P6A A;  3O8E A;  1QHV A;  4K6W A;  4LIY A;  1UXA A;  2BZV A;  3QND A;  4XQB A;  3L88 A;  4ZDG A;  4ATZ A;  3L89 A;  4K6T A;  2J1K C;  1NOB A;  2BZU A;  3BQ4 A;  2J12 A;  3N0I A; 
#chains in the Genus database with same CATH topology
 4K6U A;  2WBW A;  1UXB A;  3F0Y A;  5MHS A;  1QIU A;  1UXE A;  4XL8 A;  4GU3 A;  2IUN A;  2WGU A;  2W9L C;  2BT7 A;  1P69 A;  2WST A;  4D62 A;  1KNB A;  2O39 A;  3EXW A;  2OJ5 A;  4XC5 A;  3EXV A;  1H7Z A;  1KKE A;  2BT8 A;  2QLK A;  2VTW A;  2WBV A;  4CW8 A;  2J2J A;  4D63 A;  1KAC A;  2JJL A;  4XQA A;  2WGT A;  4WYJ A;  3CNC A;  4K6V A;  1P6A A;  3O8E A;  1QHV A;  4K6W A;  4LIY A;  2OJ6 A;  2VRS A;  3EOY A;  3ZPE A;  1UXA A;  2BSF A;  2BZV A;  3QND A;  4XQB A;  3ZPF A;  3L88 A;  4ODB A;  4ZDG A;  4ATZ A;  3L89 A;  3S6X A;  2IUM A;  4K6T A;  2J1K C;  1NOB A;  2BZU A;  3BQ4 A;  2J12 A;  4GU4 A;  3N0I A; 
#chains in the Genus database with same CATH homology
 4K6U A;  2WBW A;  1UXB A;  3F0Y A;  1QIU A;  1UXE A;  4XL8 A;  2WGU A;  2W9L C;  1P69 A;  2WST A;  1KNB A;  2O39 A;  3EXW A;  3EXV A;  1H7Z A;  2QLK A;  2WBV A;  2J2J A;  1KAC A;  4XQA A;  2WGT A;  4WYJ A;  3CNC A;  4K6V A;  1P6A A;  3O8E A;  1QHV A;  4K6W A;  4LIY A;  1UXA A;  2BZV A;  3QND A;  4XQB A;  3L88 A;  4ZDG A;  4ATZ A;  3L89 A;  4K6T A;  2J1K C;  1NOB A;  2BZU A;  3BQ4 A;  2J12 A;  3N0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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