1LY7A

The solution structure of the the c-terminal domain of frataxin, the protein responsible for friedreich ataxia
Total Genus 21
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
121
structure length
121
Chain Sequence
MDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords frataxin
total genus 21
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2002-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 1ly7A00
3S5DA 3T3LA 1LY7A 1EKGA 3OEQA 2FQLA 3T3TA 4HS5A 2GA5A 1SOYA 2EFFA 3T3JA 4LK8A 1EW4A 3T3XA 4JPDA 2P1XA 3OERA 3S4MA 3S5EA 3T3KA 4LP1A 3S5FA 4EC2A
chains in the Genus database with same CATH superfamily
1V5RA 3S5DA 3T3LA 3GD9A 1LY7A 1D2MA 1EKGA 2FQLA 3OEQA 4P78C 3I9V7 4HS5A 3T3TA 2GA5A 4C26A 1SOYA 2EFFA 3T3JA 4LK8A 1EW4A 3IMOA 3SSCA 3SSEA 3A5PA 3SSDA 3T3XA 4JPDA 3GD0A 2P1XA 4HEA7 2FUG7 1WHZA 3OERA 3IAM7 3S4MA 3S5EA 3T3KA 4LP1A 3S5FA 4EC2A 3IAS7
chains in the Genus database with same CATH topology
3S5DA 3T3LA 1LY7A 1EKGA 3OEQA 2FQLA 3T3TA 4HS5A 2GA5A 1SOYA 2EFFA 3T3JA 4LK8A 1EW4A 3T3XA 4JPDA 2P1XA 3OERA 3S4MA 3S5EA 3T3KA 4LP1A 3S5FA 4EC2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S5D A;  3T3L A;  1LY7 A;  1EKG A;  3OEQ A;  2FQL A;  3T3T A;  4HS5 A;  2GA5 A;  1SOY A;  2EFF A;  3T3J A;  4LK8 A;  1EW4 A;  3T3X A;  4JPD A;  2P1X A;  3OER A;  3S4M A;  3S5E A;  3T3K A;  4LP1 A;  3S5F A;  4EC2 A; 
#chains in the Genus database with same CATH topology
 1V5R A;  3S5D A;  3T3L A;  3GD9 A;  1LY7 A;  1D2M A;  1EKG A;  2FQL A;  3OEQ A;  4P78 C;  3I9V 7;  4HS5 A;  3T3T A;  2GA5 A;  4C26 A;  1SOY A;  2EFF A;  3T3J A;  4LK8 A;  1EW4 A;  3IMO A;  3SSC A;  3SSE A;  3A5P A;  3SSD A;  3T3X A;  4JPD A;  3GD0 A;  2P1X A;  4HEA 7;  2FUG 7;  1WHZ A;  3OER A;  3IAM 7;  3S4M A;  3S5E A;  3T3K A;  4LP1 A;  3S5F A;  4EC2 A;  3IAS 7; 
#chains in the Genus database with same CATH homology
 3S5D A;  3T3L A;  1LY7 A;  1EKG A;  3OEQ A;  2FQL A;  3T3T A;  4HS5 A;  2GA5 A;  1SOY A;  2EFF A;  3T3J A;  4LK8 A;  1EW4 A;  3T3X A;  4JPD A;  2P1X A;  3OER A;  3S4M A;  3S5E A;  3T3K A;  4LP1 A;  3S5F A;  4EC2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...