3S5DA

Crystal structure of human frataxin variant w155a
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
121
structure length
121
Chain Sequence
LDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIALSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
molecule tags Unknown function
source organism Homo sapiens
total genus 34
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s5dA00
3S4MA 2FQLA 3T3JA 4LK8A 1EKGA 3OERA 1LY7A 3T3XA 4HS5A 3T3TA 1SOYA 2GA5A 3T3LA 4EC2A 3T3KA 3OEQA 4LP1A 3S5EA 3S5DA 2P1XA 2EFFA 4JPDA 1EW4A 3S5FA
chains in the Genus database with same CATH superfamily
4HEA7 3GD0A 3S4MA 3SSDA 2FQLA 3T3JA 3I9V7 4LK8A 1EKGA 3OERA 4P78C 1LY7A 2FUG7 3IMOA 3T3XA 3A5PA 4HS5A 3T3TA 1SOYA 4C26A 2GA5A 3T3LA 4EC2A 3SSCA 3T3KA 3IAS7 3OEQA 4LP1A 3GD9A 3IAM7 3S5DA 3S5EA 2P1XA 1V5RA 1D2MA 1WHZA 2EFFA 4JPDA 1EW4A 3SSEA 3S5FA
chains in the Genus database with same CATH topology
3S4MA 2FQLA 3T3JA 4LK8A 1EKGA 3OERA 1LY7A 3T3XA 4HS5A 3T3TA 1SOYA 2GA5A 3T3LA 4EC2A 3T3KA 3OEQA 4LP1A 3S5EA 3S5DA 2P1XA 2EFFA 4JPDA 1EW4A 3S5FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S4M A;  2FQL A;  3T3J A;  4LK8 A;  1EKG A;  3OER A;  1LY7 A;  3T3X A;  4HS5 A;  3T3T A;  1SOY A;  2GA5 A;  3T3L A;  4EC2 A;  3T3K A;  3OEQ A;  4LP1 A;  3S5E A;  3S5D A;  2P1X A;  2EFF A;  4JPD A;  1EW4 A;  3S5F A; 
#chains in the Genus database with same CATH topology
 4HEA 7;  3GD0 A;  3S4M A;  3SSD A;  2FQL A;  3T3J A;  3I9V 7;  4LK8 A;  1EKG A;  3OER A;  4P78 C;  1LY7 A;  2FUG 7;  3IMO A;  3T3X A;  3A5P A;  4HS5 A;  3T3T A;  1SOY A;  4C26 A;  2GA5 A;  3T3L A;  4EC2 A;  3SSC A;  3T3K A;  3IAS 7;  3OEQ A;  4LP1 A;  3GD9 A;  3IAM 7;  3S5D A;  3S5E A;  2P1X A;  1V5R A;  1D2M A;  1WHZ A;  2EFF A;  4JPD A;  1EW4 A;  3SSE A;  3S5F A; 
#chains in the Genus database with same CATH homology
 3S4M A;  2FQL A;  3T3J A;  4LK8 A;  1EKG A;  3OER A;  1LY7 A;  3T3X A;  4HS5 A;  3T3T A;  1SOY A;  2GA5 A;  3T3L A;  4EC2 A;  3T3K A;  3OEQ A;  4LP1 A;  3S5E A;  3S5D A;  2P1X A;  2EFF A;  4JPD A;  1EW4 A;  3S5F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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