1P69A

Structural basis for variation in adenovirus affinity for the cellular receptor car (p417s mutant)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
185
structure length
185
Chain Sequence
TPYDPLTLWTTPDPSPNCSLIQELDAKLTLCLTKNGSIVNGIVSLVGVKGNLLNIQSTTTTVGVHLVFDEQGRLITSTPTALVPQASWGYRQGQSVSTNTVTNGLGFMPNVSAYPRPNASEAKSQMVSLTYLQGDTSKPITMKVAFNGITSLNGYSLTFMWSGLSNYINQPFSTPSCSFSYITQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein/receptor
source organism Human adenovirus a serotype 12
publication title Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
pubmed doi rcsb
molecule keywords Fiber protein
total genus 37
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2003-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 1p69A00
2J1KC 3BQ4A 4XQBA 1KNBA 2J2JA 3L88A 4LIYA 4XQAA 2W9LC 3EXWA 2BZVA 1UXEA 1QIUA 2WSTA 2O39A 4K6WA 1QHVA 3EXVA 4ZDGA 2QLKA 2WBVA 2WBWA 3N0IA 1KACA 1UXBA 4K6TA 1H7ZA 2WGTA 4K6UA 1P69A 4WYJA 2WGUA 2BZUA 3CNCA 1P6AA 2J12A 3O8EA 1UXAA 4K6VA 4XL8A 3F0YA 4ATZA 3QNDA 1NOBA 3L89A
chains in the Genus database with same CATH superfamily
2J1KC 3BQ4A 4D63A 5MHSA 2JJLA 4XQBA 1KNBA 2J2JA 3L88A 4LIYA 3ZPFA 4ODBA 2BSFA 2W9LC 3EXWA 4XQAA 2BZVA 1UXEA 1QIUA 2BT7A 2WSTA 2O39A 4K6WA 1QHVA 3EXVA 2BT8A 4XC5A 4GU3A 4D62A 3EOYA 4ZDGA 2VRSA 2QLKA 2WBVA 2WBWA 3N0IA 1KACA 1UXBA 4K6TA 1H7ZA 2WGTA 4K6UA 1P69A 2OJ6A 4WYJA 2WGUA 2BZUA 2VTWA 1P6AA 3CNCA 2IUMA 1KKEA 4GU4A 2J12A 3O8EA 1UXAA 4K6VA 4XL8A 3F0YA 3S6XA 4ATZA 4CW8A 3QNDA 2IUNA 2OJ5A 1NOBA 3L89A 3ZPEA
chains in the Genus database with same CATH topology
2J1KC 3BQ4A 4XQBA 1KNBA 2J2JA 3L88A 4LIYA 4XQAA 2W9LC 3EXWA 2BZVA 1UXEA 1QIUA 2WSTA 2O39A 4K6WA 1QHVA 3EXVA 4ZDGA 2QLKA 2WBVA 2WBWA 3N0IA 1KACA 1UXBA 4K6TA 1H7ZA 2WGTA 4K6UA 1P69A 4WYJA 2WGUA 2BZUA 3CNCA 1P6AA 2J12A 3O8EA 1UXAA 4K6VA 4XL8A 3F0YA 4ATZA 3QNDA 1NOBA 3L89A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J1K C;  3BQ4 A;  4XQB A;  1KNB A;  2J2J A;  3L88 A;  4LIY A;  4XQA A;  2W9L C;  3EXW A;  2BZV A;  1UXE A;  1QIU A;  2WST A;  2O39 A;  4K6W A;  1QHV A;  3EXV A;  4ZDG A;  2QLK A;  2WBV A;  2WBW A;  3N0I A;  1KAC A;  1UXB A;  4K6T A;  1H7Z A;  2WGT A;  4K6U A;  1P69 A;  4WYJ A;  2WGU A;  2BZU A;  3CNC A;  1P6A A;  2J12 A;  3O8E A;  1UXA A;  4K6V A;  4XL8 A;  3F0Y A;  4ATZ A;  3QND A;  1NOB A;  3L89 A; 
#chains in the Genus database with same CATH topology
 2J1K C;  3BQ4 A;  4D63 A;  5MHS A;  2JJL A;  4XQB A;  1KNB A;  2J2J A;  3L88 A;  4LIY A;  3ZPF A;  4ODB A;  2BSF A;  2W9L C;  3EXW A;  4XQA A;  2BZV A;  1UXE A;  1QIU A;  2BT7 A;  2WST A;  2O39 A;  4K6W A;  1QHV A;  3EXV A;  2BT8 A;  4XC5 A;  4GU3 A;  4D62 A;  3EOY A;  4ZDG A;  2VRS A;  2QLK A;  2WBV A;  2WBW A;  3N0I A;  1KAC A;  1UXB A;  4K6T A;  1H7Z A;  2WGT A;  4K6U A;  1P69 A;  2OJ6 A;  4WYJ A;  2WGU A;  2BZU A;  2VTW A;  1P6A A;  3CNC A;  2IUM A;  1KKE A;  4GU4 A;  2J12 A;  3O8E A;  1UXA A;  4K6V A;  4XL8 A;  3F0Y A;  3S6X A;  4ATZ A;  4CW8 A;  3QND A;  2IUN A;  2OJ5 A;  1NOB A;  3L89 A;  3ZPE A; 
#chains in the Genus database with same CATH homology
 2J1K C;  3BQ4 A;  4XQB A;  1KNB A;  2J2J A;  3L88 A;  4LIY A;  4XQA A;  2W9L C;  3EXW A;  2BZV A;  1UXE A;  1QIU A;  2WST A;  2O39 A;  4K6W A;  1QHV A;  3EXV A;  4ZDG A;  2QLK A;  2WBV A;  2WBW A;  3N0I A;  1KAC A;  1UXB A;  4K6T A;  1H7Z A;  2WGT A;  4K6U A;  1P69 A;  4WYJ A;  2WGU A;  2BZU A;  3CNC A;  1P6A A;  2J12 A;  3O8E A;  1UXA A;  4K6V A;  4XL8 A;  3F0Y A;  4ATZ A;  3QND A;  1NOB A;  3L89 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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