1P6AA

Structural basis for variation in adenovirus affinity for the cellular receptor car (s489y mutant)
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
185
structure length
185
Chain Sequence
TPYDPLTLWTTPDPPPNCSLIQELDAKLTLCLTKNGSIVNGIVSLVGVKGNLLNIQSTTTTVGVHLVFDEQGRLITSTPTALVPQAYWGYRQGQSVSTNTVTNGLGFMPNVSAYPRPNASEAKSQMVSLTYLQGDTSKPITMKVAFNGITSLNGYSLTFMWSGLSNYINQPFSTPSCSFSYITQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
pubmed doi rcsb
molecule tags Viral protein/receptor
source organism Human adenovirus a serotype 12
molecule keywords Fiber protein
total genus 36
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2003-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 1p6aA00
2WBVA 3L89A 2J1KC 4ZDGA 1QHVA 1P69A 4K6UA 2J12A 4XL8A 3QNDA 1KACA 2BZVA 4WYJA 1P6AA 1UXEA 3O8EA 4K6VA 1UXBA 4ATZA 4K6TA 4LIYA 3EXVA 3N0IA 1H7ZA 2O39A 3L88A 2J2JA 2WSTA 1NOBA 2QLKA 3F0YA 1UXAA 2WGUA 2BZUA 4XQAA 4XQBA 4K6WA 2W9LC 1QIUA 3BQ4A 3EXWA 1KNBA 2WGTA 2WBWA 3CNCA
chains in the Genus database with same CATH superfamily
2WBVA 3L89A 2J1KC 2OJ5A 4ZDGA 1QHVA 1P69A 4K6UA 2J12A 4XL8A 3QNDA 1KKEA 1KACA 2BSFA 2BZVA 2JJLA 4WYJA 1P6AA 1UXEA 3O8EA 2IUMA 4GU3A 4ODBA 4XC5A 5MHSA 4CW8A 2VTWA 1UXBA 4K6VA 4K6TA 4ATZA 4LIYA 3EXVA 4D63A 2BT8A 1H7ZA 2OJ6A 2VRSA 3N0IA 2O39A 2IUNA 3L88A 2J2JA 2WSTA 1NOBA 4GU4A 2QLKA 3F0YA 3ZPFA 1UXAA 2WGUA 2BZUA 3S6XA 4XQAA 3ZPEA 4XQBA 4K6WA 2W9LC 1QIUA 3BQ4A 3EOYA 3EXWA 1KNBA 2WGTA 2BT7A 4D62A 2WBWA 3CNCA
chains in the Genus database with same CATH topology
2WBVA 3L89A 2J1KC 4ZDGA 1QHVA 1P69A 4K6UA 2J12A 4XL8A 3QNDA 1KACA 2BZVA 4WYJA 1P6AA 1UXEA 3O8EA 4K6VA 1UXBA 4ATZA 4K6TA 4LIYA 3EXVA 3N0IA 1H7ZA 2O39A 3L88A 2J2JA 2WSTA 1NOBA 2QLKA 3F0YA 1UXAA 2WGUA 2BZUA 4XQAA 4XQBA 4K6WA 2W9LC 1QIUA 3BQ4A 3EXWA 1KNBA 2WGTA 2WBWA 3CNCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WBV A;  3L89 A;  2J1K C;  4ZDG A;  1QHV A;  1P69 A;  4K6U A;  2J12 A;  4XL8 A;  3QND A;  1KAC A;  2BZV A;  4WYJ A;  1P6A A;  1UXE A;  3O8E A;  4K6V A;  1UXB A;  4ATZ A;  4K6T A;  4LIY A;  3EXV A;  3N0I A;  1H7Z A;  2O39 A;  3L88 A;  2J2J A;  2WST A;  1NOB A;  2QLK A;  3F0Y A;  1UXA A;  2WGU A;  2BZU A;  4XQA A;  4XQB A;  4K6W A;  2W9L C;  1QIU A;  3BQ4 A;  3EXW A;  1KNB A;  2WGT A;  2WBW A;  3CNC A; 
#chains in the Genus database with same CATH topology
 2WBV A;  3L89 A;  2J1K C;  2OJ5 A;  4ZDG A;  1QHV A;  1P69 A;  4K6U A;  2J12 A;  4XL8 A;  3QND A;  1KKE A;  1KAC A;  2BSF A;  2BZV A;  2JJL A;  4WYJ A;  1P6A A;  1UXE A;  3O8E A;  2IUM A;  4GU3 A;  4ODB A;  4XC5 A;  5MHS A;  4CW8 A;  2VTW A;  1UXB A;  4K6V A;  4K6T A;  4ATZ A;  4LIY A;  3EXV A;  4D63 A;  2BT8 A;  1H7Z A;  2OJ6 A;  2VRS A;  3N0I A;  2O39 A;  2IUN A;  3L88 A;  2J2J A;  2WST A;  1NOB A;  4GU4 A;  2QLK A;  3F0Y A;  3ZPF A;  1UXA A;  2WGU A;  2BZU A;  3S6X A;  4XQA A;  3ZPE A;  4XQB A;  4K6W A;  2W9L C;  1QIU A;  3BQ4 A;  3EOY A;  3EXW A;  1KNB A;  2WGT A;  2BT7 A;  4D62 A;  2WBW A;  3CNC A; 
#chains in the Genus database with same CATH homology
 2WBV A;  3L89 A;  2J1K C;  4ZDG A;  1QHV A;  1P69 A;  4K6U A;  2J12 A;  4XL8 A;  3QND A;  1KAC A;  2BZV A;  4WYJ A;  1P6A A;  1UXE A;  3O8E A;  4K6V A;  1UXB A;  4ATZ A;  4K6T A;  4LIY A;  3EXV A;  3N0I A;  1H7Z A;  2O39 A;  3L88 A;  2J2J A;  2WST A;  1NOB A;  2QLK A;  3F0Y A;  1UXA A;  2WGU A;  2BZU A;  4XQA A;  4XQB A;  4K6W A;  2W9L C;  1QIU A;  3BQ4 A;  3EXW A;  1KNB A;  2WGT A;  2WBW A;  3CNC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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