1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
molecule tags Toxin
molecule keywords Toxin APETx2
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
3D4UB 2BDSA 2MN3A 2SH1A 2H9XA 1BDSA 1Z99A 1B8WA 1AHLA 1WXNA 3LMSB 2RNGA 1H5OA 2JTOA 2MUBA 1SHIA 1WQKA 1ZUEA 4GV5A 1D6BA 1ZLIB 2K2XA 1ATXA 1ZLHB 1APFA 1SH1A 1ZUFA
chains in the Genus database with same CATH superfamily
3D4UB 2QSFA 2BDSA 4YIRA 2MN3A 2SH1A 2H9XA 1BDSA 1Z99A 3IF4A 1B8WA 1AHLA 1WXNA 2HJEA 2QSGA 2XXLA 3LMSB 2IKDA 2DLAA 2QSHA 3KEZA 2RNGA 1H5OA 1ZHHB 2JTOA 2MUBA 1SHIA 3C30A 1WQKA 1ZUEA 4GV5A 1GKUB 1D6BA 3MCXA 1ZLIB 2IKEA 2K2XA 3MYVA 1EL6A 1ATXA 3C38A 1ZLHB 2B9KA 1APFA 2HJ9C 1GL9B 2JR3A 1SH1A 1ZUFA
chains in the Genus database with same CATH topology
3D4UB 2QSFA 2BDSA 4YIRA 2MN3A 2SH1A 2H9XA 1BDSA 1Z99A 1B8WA 1AHLA 1WXNA 2HJEA 2QSGA 2XXLA 3LMSB 2IKDA 2DLAA 2QSHA 3KEZA 2RNGA 1H5OA 1ZHHB 2JTOA 2MUBA 1SHIA 3C30A 1WQKA 1ZUEA 4GV5A 1D6BA 3MCXA 1ZLIB 2IKEA 2K2XA 3MYVA 1ATXA 3C38A 1ZLHB 2B9KA 1APFA 2HJ9C 2JR3A 1SH1A 1ZUFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D4U B;  2BDS A;  2MN3 A;  2SH1 A;  2H9X A;  1BDS A;  1Z99 A;  1B8W A;  1AHL A;  1WXN A;  3LMS B;  2RNG A;  1H5O A;  2JTO A;  2MUB A;  1SHI A;  1WQK A;  1ZUE A;  4GV5 A;  1D6B A;  1ZLI B;  2K2X A;  1ATX A;  1ZLH B;  1APF A;  1SH1 A;  1ZUF A; 
#chains in the Genus database with same CATH topology
 3D4U B;  2QSF A;  2BDS A;  4YIR A;  2MN3 A;  2SH1 A;  2H9X A;  1BDS A;  1Z99 A;  3IF4 A;  1B8W A;  1AHL A;  1WXN A;  2HJE A;  2QSG A;  2XXL A;  3LMS B;  2IKD A;  2DLA A;  2QSH A;  3KEZ A;  2RNG A;  1H5O A;  1ZHH B;  2JTO A;  2MUB A;  1SHI A;  3C30 A;  1WQK A;  1ZUE A;  4GV5 A;  1GKU B;  1D6B A;  3MCX A;  1ZLI B;  2IKE A;  2K2X A;  3MYV A;  1EL6 A;  1ATX A;  3C38 A;  1ZLH B;  2B9K A;  1APF A;  2HJ9 C;  1GL9 B;  2JR3 A;  1SH1 A;  1ZUF A; 
#chains in the Genus database with same CATH homology
 3D4U B;  2QSF A;  2BDS A;  4YIR A;  2MN3 A;  2SH1 A;  2H9X A;  1BDS A;  1Z99 A;  1B8W A;  1AHL A;  1WXN A;  2HJE A;  2QSG A;  2XXL A;  3LMS B;  2IKD A;  2DLA A;  2QSH A;  3KEZ A;  2RNG A;  1H5O A;  1ZHH B;  2JTO A;  2MUB A;  1SHI A;  3C30 A;  1WQK A;  1ZUE A;  4GV5 A;  1D6B A;  3MCX A;  1ZLI B;  2IKE A;  2K2X A;  3MYV A;  1ATX A;  3C38 A;  1ZLH B;  2B9K A;  1APF A;  2HJ9 C;  2JR3 A;  1SH1 A;  1ZUF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...