1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
molecule keywords Toxin APETx2
molecule tags Toxin
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
1B8WA 1ZUFA 1SHIA 1SH1A 2BDSA 1ATXA 1BDSA 1AHLA 3LMSB 1ZLIB 2H9XA 1ZUEA 1WQKA 2K2XA 1WXNA 4GV5A 1ZLHB 1Z99A 1H5OA 2JTOA 2MN3A 1APFA 1D6BA 2MUBA 2RNGA 3D4UB 2SH1A
chains in the Genus database with same CATH superfamily
1B8WA 1ZUFA 1SHIA 2QSHA 1SH1A 1GKUB 3C30A 2BDSA 2IKEA 1ATXA 2JR3A 1BDSA 2QSFA 1AHLA 3LMSB 2XXLA 1ZLIB 2B9KA 2H9XA 1ZUEA 1WQKA 3C38A 3MYVA 4YIRA 2QSGA 2HJEA 1WXNA 2K2XA 4GV5A 3MCXA 2DLAA 1ZLHB 1GL9B 1Z99A 1H5OA 3IF4A 3KEZA 1EL6A 2IKDA 2HJ9C 2JTOA 2MN3A 1APFA 1D6BA 2MUBA 1ZHHB 2RNGA 3D4UB 2SH1A
chains in the Genus database with same CATH topology
1B8WA 1ZUFA 1SHIA 2QSHA 1SH1A 3C30A 2BDSA 2IKEA 1ATXA 2JR3A 1BDSA 2QSFA 1AHLA 3LMSB 2XXLA 1ZLIB 2B9KA 2H9XA 1ZUEA 1WQKA 3C38A 3MYVA 4YIRA 2QSGA 2HJEA 1WXNA 2K2XA 4GV5A 3MCXA 2DLAA 1ZLHB 1Z99A 1H5OA 3KEZA 2IKDA 2HJ9C 2JTOA 2MN3A 1APFA 1D6BA 2MUBA 1ZHHB 2RNGA 3D4UB 2SH1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B8W A;  1ZUF A;  1SHI A;  1SH1 A;  2BDS A;  1ATX A;  1BDS A;  1AHL A;  3LMS B;  1ZLI B;  2H9X A;  1ZUE A;  1WQK A;  2K2X A;  1WXN A;  4GV5 A;  1ZLH B;  1Z99 A;  1H5O A;  2JTO A;  2MN3 A;  1APF A;  1D6B A;  2MUB A;  2RNG A;  3D4U B;  2SH1 A; 
#chains in the Genus database with same CATH topology
 1B8W A;  1ZUF A;  1SHI A;  2QSH A;  1SH1 A;  1GKU B;  3C30 A;  2BDS A;  2IKE A;  1ATX A;  2JR3 A;  1BDS A;  2QSF A;  1AHL A;  3LMS B;  2XXL A;  1ZLI B;  2B9K A;  2H9X A;  1ZUE A;  1WQK A;  3C38 A;  3MYV A;  4YIR A;  2QSG A;  2HJE A;  1WXN A;  2K2X A;  4GV5 A;  3MCX A;  2DLA A;  1ZLH B;  1GL9 B;  1Z99 A;  1H5O A;  3IF4 A;  3KEZ A;  1EL6 A;  2IKD A;  2HJ9 C;  2JTO A;  2MN3 A;  1APF A;  1D6B A;  2MUB A;  1ZHH B;  2RNG A;  3D4U B;  2SH1 A; 
#chains in the Genus database with same CATH homology
 1B8W A;  1ZUF A;  1SHI A;  2QSH A;  1SH1 A;  3C30 A;  2BDS A;  2IKE A;  1ATX A;  2JR3 A;  1BDS A;  2QSF A;  1AHL A;  3LMS B;  2XXL A;  1ZLI B;  2B9K A;  2H9X A;  1ZUE A;  1WQK A;  3C38 A;  3MYV A;  4YIR A;  2QSG A;  2HJE A;  1WXN A;  2K2X A;  4GV5 A;  3MCX A;  2DLA A;  1ZLH B;  1Z99 A;  1H5O A;  3KEZ A;  2IKD A;  2HJ9 C;  2JTO A;  2MN3 A;  1APF A;  1D6B A;  2MUB A;  1ZHH B;  2RNG A;  3D4U B;  2SH1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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