2K2XA

Solution structure of tick carboxypeptidase inhibitor at ph 3.5
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase inhibitor
molecule keywords Carboxypeptidase inhibitor
publication title The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
pubmed doi rcsb
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2008-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA01
2H9XA 1ZLHB 2JTOA 1ZLIB 1ZUFA 1BDSA 2BDSA 1ZUEA 1H5OA 1Z99A 2RNGA 1WXNA 1ATXA 1B8WA 2SH1A 3LMSB 1APFA 1D6BA 1SHIA 4GV5A 2MN3A 1AHLA 3D4UB 2K2XA 2MUBA 1WQKA 1SH1A
chains in the Genus database with same CATH superfamily
2H9XA 1ZLHB 2JTOA 1ZLIB 1ZUFA 1BDSA 4YIRA 2BDSA 2B9KA 2XXLA 3C30A 2QSGA 3C38A 1EL6A 1ZHHB 2QSFA 1ZUEA 3MCXA 1GL9B 1H5OA 3IF4A 1Z99A 2HJEA 2RNGA 1WXNA 1ATXA 1B8WA 2HJ9C 2SH1A 2IKEA 2DLAA 3LMSB 1APFA 1D6BA 2QSHA 1SHIA 4GV5A 2MN3A 1AHLA 3D4UB 3KEZA 2K2XA 3MYVA 2IKDA 2MUBA 1SH1A 1WQKA 2JR3A 1GKUB
chains in the Genus database with same CATH topology
2H9XA 1ZLHB 2JTOA 1ZLIB 1ZUFA 1BDSA 4YIRA 2BDSA 2B9KA 2XXLA 3C30A 2QSGA 3C38A 2QSFA 1ZHHB 1ZUEA 3MCXA 1H5OA 1Z99A 2HJEA 2RNGA 1WXNA 1ATXA 1B8WA 2HJ9C 2SH1A 2IKEA 2DLAA 3LMSB 1APFA 1D6BA 1SHIA 4GV5A 2MN3A 1AHLA 3D4UB 3KEZA 2K2XA 3MYVA 2IKDA 2MUBA 1WQKA 1SH1A 2JR3A 2QSHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H9X A;  1ZLH B;  2JTO A;  1ZLI B;  1ZUF A;  1BDS A;  2BDS A;  1ZUE A;  1H5O A;  1Z99 A;  2RNG A;  1WXN A;  1ATX A;  1B8W A;  2SH1 A;  3LMS B;  1APF A;  1D6B A;  1SHI A;  4GV5 A;  2MN3 A;  1AHL A;  3D4U B;  2K2X A;  2MUB A;  1WQK A;  1SH1 A; 
#chains in the Genus database with same CATH topology
 2H9X A;  1ZLH B;  2JTO A;  1ZLI B;  1ZUF A;  1BDS A;  4YIR A;  2BDS A;  2B9K A;  2XXL A;  3C30 A;  2QSG A;  3C38 A;  1EL6 A;  1ZHH B;  2QSF A;  1ZUE A;  3MCX A;  1GL9 B;  1H5O A;  3IF4 A;  1Z99 A;  2HJE A;  2RNG A;  1WXN A;  1ATX A;  1B8W A;  2HJ9 C;  2SH1 A;  2IKE A;  2DLA A;  3LMS B;  1APF A;  1D6B A;  2QSH A;  1SHI A;  4GV5 A;  2MN3 A;  1AHL A;  3D4U B;  3KEZ A;  2K2X A;  3MYV A;  2IKD A;  2MUB A;  1SH1 A;  1WQK A;  2JR3 A;  1GKU B; 
#chains in the Genus database with same CATH homology
 2H9X A;  1ZLH B;  2JTO A;  1ZLI B;  1ZUF A;  1BDS A;  4YIR A;  2BDS A;  2B9K A;  2XXL A;  3C30 A;  2QSG A;  3C38 A;  2QSF A;  1ZHH B;  1ZUE A;  3MCX A;  1H5O A;  1Z99 A;  2HJE A;  2RNG A;  1WXN A;  1ATX A;  1B8W A;  2HJ9 C;  2SH1 A;  2IKE A;  2DLA A;  3LMS B;  1APF A;  1D6B A;  1SHI A;  4GV5 A;  2MN3 A;  1AHL A;  3D4U B;  3KEZ A;  2K2X A;  3MYV A;  2IKD A;  2MUB A;  1WQK A;  1SH1 A;  2JR3 A;  2QSH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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