1WQKA

Solution structure of apetx1, a specific peptide inhibitor of human ether-a-go-go-related gene potassium channels from the venom of the sea anemone anthopleura elegantissima: a new fold for an herg toxin
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
42
structure length
42
Chain Sequence
GTTCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
pubmed doi rcsb
molecule tags Toxin
molecule keywords Toxin APETx1
total genus 4
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2004-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wqkA00
1SHIA 1B8WA 1ZUFA 1ZUEA 1D6BA 2K2XA 1ZLIB 2SH1A 4GV5A 2RNGA 2H9XA 1H5OA 2MUBA 1WXNA 1BDSA 3LMSB 1ATXA 1WQKA 1SH1A 1Z99A 2BDSA 1APFA 2MN3A 2JTOA 3D4UB 1ZLHB 1AHLA
chains in the Genus database with same CATH superfamily
1SHIA 1B8WA 1ZUFA 1ZUEA 1D6BA 2K2XA 2QSFA 2HJEA 3C38A 1ZLIB 2SH1A 2B9KA 2RNGA 4GV5A 2QSGA 4YIRA 2H9XA 1H5OA 3C30A 3MYVA 1GKUB 1EL6A 3KEZA 1WXNA 2MUBA 1BDSA 2IKEA 3LMSB 1ATXA 3MCXA 2QSHA 1ZHHB 2JR3A 1GL9B 1WQKA 1SH1A 1Z99A 2BDSA 1APFA 2MN3A 2HJ9C 2JTOA 2XXLA 3D4UB 3IF4A 1AHLA 2DLAA 1ZLHB 2IKDA
chains in the Genus database with same CATH topology
1SHIA 1B8WA 1ZUFA 1ZUEA 1D6BA 2K2XA 2QSFA 2HJEA 3C38A 1ZLIB 2SH1A 2B9KA 2RNGA 4GV5A 2QSGA 4YIRA 2H9XA 1H5OA 3C30A 3MYVA 3KEZA 1WXNA 2MUBA 1BDSA 2IKEA 3LMSB 1ATXA 3MCXA 2QSHA 1ZHHB 2JR3A 1WQKA 1SH1A 1Z99A 2BDSA 1APFA 2MN3A 2HJ9C 2JTOA 2XXLA 3D4UB 1AHLA 2DLAA 1ZLHB 2IKDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SHI A;  1B8W A;  1ZUF A;  1ZUE A;  1D6B A;  2K2X A;  1ZLI B;  2SH1 A;  4GV5 A;  2RNG A;  2H9X A;  1H5O A;  2MUB A;  1WXN A;  1BDS A;  3LMS B;  1ATX A;  1WQK A;  1SH1 A;  1Z99 A;  2BDS A;  1APF A;  2MN3 A;  2JTO A;  3D4U B;  1ZLH B;  1AHL A; 
#chains in the Genus database with same CATH topology
 1SHI A;  1B8W A;  1ZUF A;  1ZUE A;  1D6B A;  2K2X A;  2QSF A;  2HJE A;  3C38 A;  1ZLI B;  2SH1 A;  2B9K A;  2RNG A;  4GV5 A;  2QSG A;  4YIR A;  2H9X A;  1H5O A;  3C30 A;  3MYV A;  1GKU B;  1EL6 A;  3KEZ A;  1WXN A;  2MUB A;  1BDS A;  2IKE A;  3LMS B;  1ATX A;  3MCX A;  2QSH A;  1ZHH B;  2JR3 A;  1GL9 B;  1WQK A;  1SH1 A;  1Z99 A;  2BDS A;  1APF A;  2MN3 A;  2HJ9 C;  2JTO A;  2XXL A;  3D4U B;  3IF4 A;  1AHL A;  2DLA A;  1ZLH B;  2IKD A; 
#chains in the Genus database with same CATH homology
 1SHI A;  1B8W A;  1ZUF A;  1ZUE A;  1D6B A;  2K2X A;  2QSF A;  2HJE A;  3C38 A;  1ZLI B;  2SH1 A;  2B9K A;  2RNG A;  4GV5 A;  2QSG A;  4YIR A;  2H9X A;  1H5O A;  3C30 A;  3MYV A;  3KEZ A;  1WXN A;  2MUB A;  1BDS A;  2IKE A;  3LMS B;  1ATX A;  3MCX A;  2QSH A;  1ZHH B;  2JR3 A;  1WQK A;  1SH1 A;  1Z99 A;  2BDS A;  1APF A;  2MN3 A;  2HJ9 C;  2JTO A;  2XXL A;  3D4U B;  1AHL A;  2DLA A;  1ZLH B;  2IKD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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