1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
molecule tags Toxin
molecule keywords Toxin APETx2
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
1B8WA 3D4UB 1ZUEA 1SH1A 2MN3A 1APFA 1D6BA 2BDSA 2K2XA 4GV5A 1Z99A 1ZLIB 2SH1A 2MUBA 2RNGA 1WQKA 1SHIA 1ZUFA 1ZLHB 2H9XA 1BDSA 1ATXA 3LMSB 1WXNA 2JTOA 1H5OA 1AHLA
chains in the Genus database with same CATH superfamily
1B8WA 3D4UB 1ZUEA 2QSHA 1SH1A 2MN3A 2HJ9C 1APFA 1D6BA 2BDSA 2K2XA 1ZHHB 2QSFA 4GV5A 1Z99A 2IKEA 1ZLIB 2IKDA 3C30A 2XXLA 3MCXA 2SH1A 3IF4A 2MUBA 2RNGA 1WQKA 1SHIA 1ZUFA 3MYVA 1GL9B 1ZLHB 2H9XA 2DLAA 3KEZA 1BDSA 4YIRA 1EL6A 2HJEA 1ATXA 1GKUB 3LMSB 1WXNA 2JTOA 2JR3A 3C38A 1H5OA 2B9KA 2QSGA 1AHLA
chains in the Genus database with same CATH topology
1B8WA 3D4UB 1ZUEA 2QSHA 1SH1A 2MN3A 2HJ9C 1APFA 1D6BA 2BDSA 2K2XA 1ZHHB 2QSFA 4GV5A 1Z99A 2IKEA 1ZLIB 2IKDA 3C30A 2XXLA 3MCXA 2SH1A 2MUBA 2RNGA 1WQKA 1SHIA 1ZUFA 3MYVA 1ZLHB 2H9XA 2DLAA 3KEZA 1BDSA 4YIRA 2HJEA 1ATXA 3LMSB 1WXNA 2JTOA 2JR3A 3C38A 1H5OA 2B9KA 2QSGA 1AHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B8W A;  3D4U B;  1ZUE A;  1SH1 A;  2MN3 A;  1APF A;  1D6B A;  2BDS A;  2K2X A;  4GV5 A;  1Z99 A;  1ZLI B;  2SH1 A;  2MUB A;  2RNG A;  1WQK A;  1SHI A;  1ZUF A;  1ZLH B;  2H9X A;  1BDS A;  1ATX A;  3LMS B;  1WXN A;  2JTO A;  1H5O A;  1AHL A; 
#chains in the Genus database with same CATH topology
 1B8W A;  3D4U B;  1ZUE A;  2QSH A;  1SH1 A;  2MN3 A;  2HJ9 C;  1APF A;  1D6B A;  2BDS A;  2K2X A;  1ZHH B;  2QSF A;  4GV5 A;  1Z99 A;  2IKE A;  1ZLI B;  2IKD A;  3C30 A;  2XXL A;  3MCX A;  2SH1 A;  3IF4 A;  2MUB A;  2RNG A;  1WQK A;  1SHI A;  1ZUF A;  3MYV A;  1GL9 B;  1ZLH B;  2H9X A;  2DLA A;  3KEZ A;  1BDS A;  4YIR A;  1EL6 A;  2HJE A;  1ATX A;  1GKU B;  3LMS B;  1WXN A;  2JTO A;  2JR3 A;  3C38 A;  1H5O A;  2B9K A;  2QSG A;  1AHL A; 
#chains in the Genus database with same CATH homology
 1B8W A;  3D4U B;  1ZUE A;  2QSH A;  1SH1 A;  2MN3 A;  2HJ9 C;  1APF A;  1D6B A;  2BDS A;  2K2X A;  1ZHH B;  2QSF A;  4GV5 A;  1Z99 A;  2IKE A;  1ZLI B;  2IKD A;  3C30 A;  2XXL A;  3MCX A;  2SH1 A;  2MUB A;  2RNG A;  1WQK A;  1SHI A;  1ZUF A;  3MYV A;  1ZLH B;  2H9X A;  2DLA A;  3KEZ A;  1BDS A;  4YIR A;  2HJE A;  1ATX A;  3LMS B;  1WXN A;  2JTO A;  2JR3 A;  3C38 A;  1H5O A;  2B9K A;  2QSG A;  1AHL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...