2FQLA

Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
112
structure length
112
Chain Sequence
VPQEVLNLPLEKAHEEADDYLDHLLDSLEELSEAHPDCIPDVELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTDILTEEVEKAISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.
pubmed doi rcsb
molecule keywords Frataxin homolog, mitochondrial
molecule tags Transport protein
source organism Saccharomyces cerevisiae
total genus 23
structure length 112
sequence length 112
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2006-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 2fqlA01
3S5DA 3S5EA 1EKGA 3S5FA 3T3LA 2EFFA 3T3KA 4LK8A 4HS5A 2P1XA 3OEQA 4JPDA 2FQLA 1SOYA 3T3JA 1LY7A 3T3XA 4EC2A 3OERA 3T3TA 3S4MA 2GA5A 4LP1A 1EW4A
chains in the Genus database with same CATH superfamily
4P78C 3S5DA 3S5EA 1EKGA 3S5FA 3SSDA 1WHZA 3T3LA 2EFFA 1D2MA 3IAM7 3T3KA 4LK8A 4HS5A 2P1XA 2FUG7 3IMOA 3OEQA 4JPDA 1V5RA 2FQLA 1SOYA 3IAS7 3T3JA 3GD0A 4HEA7 1LY7A 3T3XA 3SSEA 3I9V7 4EC2A 3A5PA 3SSCA 3OERA 3T3TA 3S4MA 3GD9A 4C26A 2GA5A 4LP1A 1EW4A
chains in the Genus database with same CATH topology
3S5DA 3S5EA 1EKGA 3S5FA 3T3LA 2EFFA 3T3KA 4LK8A 4HS5A 2P1XA 3OEQA 4JPDA 2FQLA 1SOYA 3T3JA 1LY7A 3T3XA 4EC2A 3OERA 3T3TA 3S4MA 2GA5A 4LP1A 1EW4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S5D A;  3S5E A;  1EKG A;  3S5F A;  3T3L A;  2EFF A;  3T3K A;  4LK8 A;  4HS5 A;  2P1X A;  3OEQ A;  4JPD A;  2FQL A;  1SOY A;  3T3J A;  1LY7 A;  3T3X A;  4EC2 A;  3OER A;  3T3T A;  3S4M A;  2GA5 A;  4LP1 A;  1EW4 A; 
#chains in the Genus database with same CATH topology
 4P78 C;  3S5D A;  3S5E A;  1EKG A;  3S5F A;  3SSD A;  1WHZ A;  3T3L A;  2EFF A;  1D2M A;  3IAM 7;  3T3K A;  4LK8 A;  4HS5 A;  2P1X A;  2FUG 7;  3IMO A;  3OEQ A;  4JPD A;  1V5R A;  2FQL A;  1SOY A;  3IAS 7;  3T3J A;  3GD0 A;  4HEA 7;  1LY7 A;  3T3X A;  3SSE A;  3I9V 7;  4EC2 A;  3A5P A;  3SSC A;  3OER A;  3T3T A;  3S4M A;  3GD9 A;  4C26 A;  2GA5 A;  4LP1 A;  1EW4 A; 
#chains in the Genus database with same CATH homology
 3S5D A;  3S5E A;  1EKG A;  3S5F A;  3T3L A;  2EFF A;  3T3K A;  4LK8 A;  4HS5 A;  2P1X A;  3OEQ A;  4JPD A;  2FQL A;  1SOY A;  3T3J A;  1LY7 A;  3T3X A;  4EC2 A;  3OER A;  3T3T A;  3S4M A;  2GA5 A;  4LP1 A;  1EW4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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