2FQLA

Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
112
structure length
112
Chain Sequence
VPQEVLNLPLEKAHEEADDYLDHLLDSLEELSEAHPDCIPDVELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTDILTEEVEKAISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.
pubmed doi rcsb
molecule tags Transport protein
source organism Saccharomyces cerevisiae
molecule keywords Frataxin homolog, mitochondrial
total genus 23
structure length 112
sequence length 112
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2006-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 2fqlA01
4EC2A 3T3TA 4HS5A 3T3KA 4LP1A 1EW4A 3S5DA 3T3LA 3S5EA 3OEQA 1EKGA 2EFFA 2GA5A 3OERA 3T3JA 4LK8A 3S5FA 3S4MA 2P1XA 1SOYA 2FQLA 1LY7A 3T3XA 4JPDA
chains in the Genus database with same CATH superfamily
1V5RA 4EC2A 2FUG7 3T3TA 3GD9A 3IAM7 4HS5A 3T3KA 1D2MA 4LP1A 1EW4A 3S5DA 3IMOA 3T3LA 3S5EA 3OEQA 1EKGA 4HEA7 3SSCA 2EFFA 2GA5A 3OERA 3T3JA 3GD0A 3SSEA 4LK8A 3S5FA 2P1XA 3S4MA 1WHZA 4C26A 1SOYA 3A5PA 2FQLA 3SSDA 4P78C 1LY7A 3T3XA 3I9V7 3IAS7 4JPDA
chains in the Genus database with same CATH topology
4EC2A 3T3TA 4HS5A 3T3KA 4LP1A 1EW4A 3S5DA 3T3LA 3S5EA 3OEQA 1EKGA 2EFFA 2GA5A 3OERA 3T3JA 4LK8A 3S5FA 3S4MA 2P1XA 1SOYA 2FQLA 1LY7A 3T3XA 4JPDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EC2 A;  3T3T A;  4HS5 A;  3T3K A;  4LP1 A;  1EW4 A;  3S5D A;  3T3L A;  3S5E A;  3OEQ A;  1EKG A;  2EFF A;  2GA5 A;  3OER A;  3T3J A;  4LK8 A;  3S5F A;  3S4M A;  2P1X A;  1SOY A;  2FQL A;  1LY7 A;  3T3X A;  4JPD A; 
#chains in the Genus database with same CATH topology
 1V5R A;  4EC2 A;  2FUG 7;  3T3T A;  3GD9 A;  3IAM 7;  4HS5 A;  3T3K A;  1D2M A;  4LP1 A;  1EW4 A;  3S5D A;  3IMO A;  3T3L A;  3S5E A;  3OEQ A;  1EKG A;  4HEA 7;  3SSC A;  2EFF A;  2GA5 A;  3OER A;  3T3J A;  3GD0 A;  3SSE A;  4LK8 A;  3S5F A;  2P1X A;  3S4M A;  1WHZ A;  4C26 A;  1SOY A;  3A5P A;  2FQL A;  3SSD A;  4P78 C;  1LY7 A;  3T3X A;  3I9V 7;  3IAS 7;  4JPD A; 
#chains in the Genus database with same CATH homology
 4EC2 A;  3T3T A;  4HS5 A;  3T3K A;  4LP1 A;  1EW4 A;  3S5D A;  3T3L A;  3S5E A;  3OEQ A;  1EKG A;  2EFF A;  2GA5 A;  3OER A;  3T3J A;  4LK8 A;  3S5F A;  3S4M A;  2P1X A;  1SOY A;  2FQL A;  1LY7 A;  3T3X A;  4JPD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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