2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule keywords Carboxypeptidase inhibitor
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
2BDSA 1Z99A 1ATXA 2MN3A 1SH1A 2SH1A 3LMSB 2H9XA 1ZLHB 1APFA 1SHIA 1BDSA 2RNGA 1D6BA 1WXNA 1AHLA 3D4UB 2MUBA 2JTOA 1WQKA 1ZUFA 4GV5A 1H5OA 2K2XA 1B8WA 1ZLIB 1ZUEA
chains in the Genus database with same CATH superfamily
1GKUB 2BDSA 1Z99A 1GL9B 1ATXA 2MN3A 3MYVA 2HJ9C 1SH1A 2XXLA 2SH1A 3C38A 3LMSB 2H9XA 1ZLHB 1EL6A 2IKEA 3C30A 1APFA 1SHIA 2QSHA 1BDSA 3KEZA 2JR3A 2RNGA 2DLAA 2HJEA 1D6BA 1WXNA 1AHLA 2QSGA 3D4UB 2MUBA 1ZHHB 2IKDA 2JTOA 1WQKA 1ZUFA 4GV5A 3IF4A 3MCXA 2B9KA 1H5OA 2QSFA 2K2XA 1B8WA 1ZLIB 1ZUEA 4YIRA
chains in the Genus database with same CATH topology
2BDSA 1Z99A 1ATXA 2MN3A 3MYVA 2HJ9C 1SH1A 2XXLA 2SH1A 3C38A 3LMSB 2H9XA 1ZLHB 2IKEA 3C30A 1APFA 1SHIA 2QSHA 1BDSA 3KEZA 2JR3A 2RNGA 2DLAA 2HJEA 1D6BA 1WXNA 1AHLA 2QSGA 3D4UB 2MUBA 1ZHHB 2IKDA 2JTOA 1WQKA 1ZUFA 4GV5A 3MCXA 2B9KA 1H5OA 2QSFA 2K2XA 1B8WA 1ZLIB 1ZUEA 4YIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BDS A;  1Z99 A;  1ATX A;  2MN3 A;  1SH1 A;  2SH1 A;  3LMS B;  2H9X A;  1ZLH B;  1APF A;  1SHI A;  1BDS A;  2RNG A;  1D6B A;  1WXN A;  1AHL A;  3D4U B;  2MUB A;  2JTO A;  1WQK A;  1ZUF A;  4GV5 A;  1H5O A;  2K2X A;  1B8W A;  1ZLI B;  1ZUE A; 
#chains in the Genus database with same CATH topology
 1GKU B;  2BDS A;  1Z99 A;  1GL9 B;  1ATX A;  2MN3 A;  3MYV A;  2HJ9 C;  1SH1 A;  2XXL A;  2SH1 A;  3C38 A;  3LMS B;  2H9X A;  1ZLH B;  1EL6 A;  2IKE A;  3C30 A;  1APF A;  1SHI A;  2QSH A;  1BDS A;  3KEZ A;  2JR3 A;  2RNG A;  2DLA A;  2HJE A;  1D6B A;  1WXN A;  1AHL A;  2QSG A;  3D4U B;  2MUB A;  1ZHH B;  2IKD A;  2JTO A;  1WQK A;  1ZUF A;  4GV5 A;  3IF4 A;  3MCX A;  2B9K A;  1H5O A;  2QSF A;  2K2X A;  1B8W A;  1ZLI B;  1ZUE A;  4YIR A; 
#chains in the Genus database with same CATH homology
 2BDS A;  1Z99 A;  1ATX A;  2MN3 A;  3MYV A;  2HJ9 C;  1SH1 A;  2XXL A;  2SH1 A;  3C38 A;  3LMS B;  2H9X A;  1ZLH B;  2IKE A;  3C30 A;  1APF A;  1SHI A;  2QSH A;  1BDS A;  3KEZ A;  2JR3 A;  2RNG A;  2DLA A;  2HJE A;  1D6B A;  1WXN A;  1AHL A;  2QSG A;  3D4U B;  2MUB A;  1ZHH B;  2IKD A;  2JTO A;  1WQK A;  1ZUF A;  4GV5 A;  3MCX A;  2B9K A;  1H5O A;  2QSF A;  2K2X A;  1B8W A;  1ZLI B;  1ZUE A;  4YIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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