2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule keywords Carboxypeptidase inhibitor
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
1ZUEA 2BDSA 1ZLIB 1AHLA 1B8WA 1ZLHB 1WXNA 1SH1A 2H9XA 1H5OA 3LMSB 4GV5A 2JTOA 1ATXA 1Z99A 2MN3A 2RNGA 1WQKA 2SH1A 1SHIA 1APFA 1BDSA 2K2XA 1ZUFA 2MUBA 3D4UB 1D6BA
chains in the Genus database with same CATH superfamily
1ZUEA 2QSFA 1GL9B 2BDSA 3C38A 2B9KA 3C30A 1ZLIB 1AHLA 2HJEA 2IKEA 4YIRA 1B8WA 1ZLHB 1WXNA 1SH1A 2H9XA 1H5OA 3LMSB 2XXLA 4GV5A 2JTOA 3MYVA 2QSHA 2DLAA 1ATXA 2QSGA 1Z99A 1ZHHB 2JR3A 2MN3A 2RNGA 1WQKA 2SH1A 1SHIA 1APFA 1BDSA 1GKUB 2K2XA 3IF4A 3MCXA 2HJ9C 1ZUFA 2MUBA 3KEZA 3D4UB 1D6BA 2IKDA 1EL6A
chains in the Genus database with same CATH topology
1ZUEA 2QSFA 2BDSA 3C38A 2B9KA 3C30A 1ZLIB 1AHLA 2IKEA 2HJEA 4YIRA 1B8WA 1ZLHB 1WXNA 1SH1A 2H9XA 1H5OA 3LMSB 2XXLA 4GV5A 2JTOA 3MYVA 2QSHA 2DLAA 1ATXA 2QSGA 1Z99A 1ZHHB 2JR3A 2MN3A 2RNGA 1WQKA 2SH1A 1SHIA 1APFA 1BDSA 2K2XA 3MCXA 2HJ9C 1ZUFA 2MUBA 3KEZA 3D4UB 1D6BA 2IKDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZUE A;  2BDS A;  1ZLI B;  1AHL A;  1B8W A;  1ZLH B;  1WXN A;  1SH1 A;  2H9X A;  1H5O A;  3LMS B;  4GV5 A;  2JTO A;  1ATX A;  1Z99 A;  2MN3 A;  2RNG A;  1WQK A;  2SH1 A;  1SHI A;  1APF A;  1BDS A;  2K2X A;  1ZUF A;  2MUB A;  3D4U B;  1D6B A; 
#chains in the Genus database with same CATH topology
 1ZUE A;  2QSF A;  1GL9 B;  2BDS A;  3C38 A;  2B9K A;  3C30 A;  1ZLI B;  1AHL A;  2HJE A;  2IKE A;  4YIR A;  1B8W A;  1ZLH B;  1WXN A;  1SH1 A;  2H9X A;  1H5O A;  3LMS B;  2XXL A;  4GV5 A;  2JTO A;  3MYV A;  2QSH A;  2DLA A;  1ATX A;  2QSG A;  1Z99 A;  1ZHH B;  2JR3 A;  2MN3 A;  2RNG A;  1WQK A;  2SH1 A;  1SHI A;  1APF A;  1BDS A;  1GKU B;  2K2X A;  3IF4 A;  3MCX A;  2HJ9 C;  1ZUF A;  2MUB A;  3KEZ A;  3D4U B;  1D6B A;  2IKD A;  1EL6 A; 
#chains in the Genus database with same CATH homology
 1ZUE A;  2QSF A;  2BDS A;  3C38 A;  2B9K A;  3C30 A;  1ZLI B;  1AHL A;  2IKE A;  2HJE A;  4YIR A;  1B8W A;  1ZLH B;  1WXN A;  1SH1 A;  2H9X A;  1H5O A;  3LMS B;  2XXL A;  4GV5 A;  2JTO A;  3MYV A;  2QSH A;  2DLA A;  1ATX A;  2QSG A;  1Z99 A;  1ZHH B;  2JR3 A;  2MN3 A;  2RNG A;  1WQK A;  2SH1 A;  1SHI A;  1APF A;  1BDS A;  2K2X A;  3MCX A;  2HJ9 C;  1ZUF A;  2MUB A;  3KEZ A;  3D4U B;  1D6B A;  2IKD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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