2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule keywords Carboxypeptidase inhibitor
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
2K2XA 1SHIA 1ZUFA 1SH1A 4GV5A 2MN3A 1D6BA 2BDSA 1B8WA 3LMSB 1ZLIB 1ZUEA 1AHLA 2MUBA 2JTOA 1Z99A 1ZLHB 1ATXA 1BDSA 1WXNA 1APFA 2SH1A 1H5OA 2RNGA 3D4UB 2H9XA 1WQKA
chains in the Genus database with same CATH superfamily
2K2XA 1SHIA 2HJEA 2QSHA 1ZUFA 1SH1A 1ZHHB 4GV5A 2MN3A 1D6BA 2BDSA 2IKEA 1B8WA 1GL9B 3LMSB 1ZLIB 1ZUEA 1GKUB 1AHLA 2MUBA 2JTOA 2IKDA 1Z99A 3KEZA 4YIRA 1ZLHB 3C30A 1ATXA 1BDSA 2QSFA 1EL6A 2HJ9C 2QSGA 1WXNA 1APFA 2B9KA 2SH1A 3IF4A 2DLAA 2RNGA 1H5OA 2XXLA 3MCXA 3D4UB 2H9XA 3MYVA 2JR3A 3C38A 1WQKA
chains in the Genus database with same CATH topology
2K2XA 1SHIA 2HJEA 2QSHA 1ZUFA 1SH1A 1ZHHB 4GV5A 2MN3A 1D6BA 2BDSA 2IKEA 1B8WA 3LMSB 1ZLIB 1ZUEA 1AHLA 2MUBA 2JTOA 2IKDA 1Z99A 3KEZA 4YIRA 1ZLHB 3C30A 1ATXA 1BDSA 2QSFA 2HJ9C 2QSGA 1WXNA 1APFA 2B9KA 2SH1A 1H5OA 2DLAA 2RNGA 2XXLA 3MCXA 3D4UB 2H9XA 3MYVA 2JR3A 3C38A 1WQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K2X A;  1SHI A;  1ZUF A;  1SH1 A;  4GV5 A;  2MN3 A;  1D6B A;  2BDS A;  1B8W A;  3LMS B;  1ZLI B;  1ZUE A;  1AHL A;  2MUB A;  2JTO A;  1Z99 A;  1ZLH B;  1ATX A;  1BDS A;  1WXN A;  1APF A;  2SH1 A;  1H5O A;  2RNG A;  3D4U B;  2H9X A;  1WQK A; 
#chains in the Genus database with same CATH topology
 2K2X A;  1SHI A;  2HJE A;  2QSH A;  1ZUF A;  1SH1 A;  1ZHH B;  4GV5 A;  2MN3 A;  1D6B A;  2BDS A;  2IKE A;  1B8W A;  1GL9 B;  3LMS B;  1ZLI B;  1ZUE A;  1GKU B;  1AHL A;  2MUB A;  2JTO A;  2IKD A;  1Z99 A;  3KEZ A;  4YIR A;  1ZLH B;  3C30 A;  1ATX A;  1BDS A;  2QSF A;  1EL6 A;  2HJ9 C;  2QSG A;  1WXN A;  1APF A;  2B9K A;  2SH1 A;  3IF4 A;  2DLA A;  2RNG A;  1H5O A;  2XXL A;  3MCX A;  3D4U B;  2H9X A;  3MYV A;  2JR3 A;  3C38 A;  1WQK A; 
#chains in the Genus database with same CATH homology
 2K2X A;  1SHI A;  2HJE A;  2QSH A;  1ZUF A;  1SH1 A;  1ZHH B;  4GV5 A;  2MN3 A;  1D6B A;  2BDS A;  2IKE A;  1B8W A;  3LMS B;  1ZLI B;  1ZUE A;  1AHL A;  2MUB A;  2JTO A;  2IKD A;  1Z99 A;  3KEZ A;  4YIR A;  1ZLH B;  3C30 A;  1ATX A;  1BDS A;  2QSF A;  2HJ9 C;  2QSG A;  1WXN A;  1APF A;  2B9K A;  2SH1 A;  1H5O A;  2DLA A;  2RNG A;  2XXL A;  3MCX A;  3D4U B;  2H9X A;  3MYV A;  2JR3 A;  3C38 A;  1WQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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