2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule keywords Carboxypeptidase inhibitor
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
1SH1A 1ZUEA 2K2XA 2RNGA 1Z99A 1ZLIB 1B8WA 2BDSA 3D4UB 1AHLA 1ATXA 4GV5A 1SHIA 3LMSB 1H5OA 1D6BA 1ZUFA 1WXNA 2JTOA 2MN3A 1APFA 1WQKA 2H9XA 2MUBA 1BDSA 1ZLHB 2SH1A
chains in the Genus database with same CATH superfamily
1SH1A 3MCXA 1ZHHB 1ZUEA 2XXLA 2K2XA 2IKEA 2SH1A 2RNGA 1Z99A 1GL9B 3C30A 1ZLIB 2QSFA 1EL6A 1B8WA 2B9KA 2BDSA 2JR3A 3D4UB 1AHLA 1ATXA 4GV5A 1SHIA 2IKDA 3LMSB 2HJEA 2QSHA 1H5OA 3MYVA 1D6BA 2QSGA 1WXNA 3IF4A 2JTOA 2MN3A 2DLAA 1APFA 1GKUB 4YIRA 1WQKA 2H9XA 2HJ9C 2MUBA 3KEZA 1BDSA 1ZLHB 3C38A 1ZUFA
chains in the Genus database with same CATH topology
1SH1A 3MCXA 1ZHHB 1ZUEA 2XXLA 2K2XA 2IKEA 2SH1A 2RNGA 1Z99A 3C30A 1ZLIB 2QSFA 1B8WA 2B9KA 2BDSA 2JR3A 3D4UB 1AHLA 1ATXA 4GV5A 1SHIA 2IKDA 3LMSB 2HJEA 2QSHA 1H5OA 3MYVA 1D6BA 2QSGA 1WXNA 2JTOA 2MN3A 2DLAA 1APFA 4YIRA 1WQKA 2H9XA 2HJ9C 2MUBA 3KEZA 1BDSA 1ZLHB 3C38A 1ZUFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SH1 A;  1ZUE A;  2K2X A;  2RNG A;  1Z99 A;  1ZLI B;  1B8W A;  2BDS A;  3D4U B;  1AHL A;  1ATX A;  4GV5 A;  1SHI A;  3LMS B;  1H5O A;  1D6B A;  1ZUF A;  1WXN A;  2JTO A;  2MN3 A;  1APF A;  1WQK A;  2H9X A;  2MUB A;  1BDS A;  1ZLH B;  2SH1 A; 
#chains in the Genus database with same CATH topology
 1SH1 A;  3MCX A;  1ZHH B;  1ZUE A;  2XXL A;  2K2X A;  2IKE A;  2SH1 A;  2RNG A;  1Z99 A;  1GL9 B;  3C30 A;  1ZLI B;  2QSF A;  1EL6 A;  1B8W A;  2B9K A;  2BDS A;  2JR3 A;  3D4U B;  1AHL A;  1ATX A;  4GV5 A;  1SHI A;  2IKD A;  3LMS B;  2HJE A;  2QSH A;  1H5O A;  3MYV A;  1D6B A;  2QSG A;  1WXN A;  3IF4 A;  2JTO A;  2MN3 A;  2DLA A;  1APF A;  1GKU B;  4YIR A;  1WQK A;  2H9X A;  2HJ9 C;  2MUB A;  3KEZ A;  1BDS A;  1ZLH B;  3C38 A;  1ZUF A; 
#chains in the Genus database with same CATH homology
 1SH1 A;  3MCX A;  1ZHH B;  1ZUE A;  2XXL A;  2K2X A;  2IKE A;  2SH1 A;  2RNG A;  1Z99 A;  3C30 A;  1ZLI B;  2QSF A;  1B8W A;  2B9K A;  2BDS A;  2JR3 A;  3D4U B;  1AHL A;  1ATX A;  4GV5 A;  1SHI A;  2IKD A;  3LMS B;  2HJE A;  2QSH A;  1H5O A;  3MYV A;  1D6B A;  2QSG A;  1WXN A;  2JTO A;  2MN3 A;  2DLA A;  1APF A;  4YIR A;  1WQK A;  2H9X A;  2HJ9 C;  2MUB A;  3KEZ A;  1BDS A;  1ZLH B;  3C38 A;  1ZUF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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