2K2X | Genus

Total Genus 9

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	9
sequence length	75
structure length	75
Chain Sequence	NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 75 atoms

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75 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase inhibitor
source organism	Rhipicephalus bursa
publication title	The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways. pubmed doi rcsb
molecule keywords	Carboxypeptidase inhibitor
total genus	9
structure length	75
sequence length	75
ec nomenclature
pdb deposition date	2008-04-15

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.20.20.10	Mainly Beta	Single Sheet	Anthopleurin-A	Anthopleurin-A	2k2xA02
2.20.20.50	Mainly Beta	Single Sheet	Anthopleurin-A	Anthopleurin-A	2k2xA01

1Z99A 2K2XA 1SHIA 2BDSA 2H9XA 4GV5A 1WQKA 3LMSB 2SH1A 1B8WA 3D4UB 1APFA 2MUBA 1SH1A 1D6BA 1AHLA 1ZUFA 1ZLHB 2MN3A 2RNGA 1ZLIB 1H5OA 1ZUEA 2JTOA 1WXNA 1BDSA 1ATXA
chains in the Genus database with same CATH superfamily

3C30A 1Z99A 2K2XA 1SHIA 2HJ9C 3MCXA 2BDSA 2H9XA 4GV5A 1GL9B 1WQKA 1ZHHB 3LMSB 2JR3A 2SH1A 1B8WA 3KEZA 1GKUB 2QSFA 3D4UB 1APFA 4YIRA 2HJEA 2MUBA 2QSHA 1SH1A 1D6BA 1AHLA 2QSGA 1ZUFA 2B9KA 2IKEA 1EL6A 1ZLHB 2MN3A 2RNGA 1ZLIB 3MYVA 1H5OA 1BDSA 1ZUEA 2IKDA 2JTOA 2XXLA 1WXNA 3IF4A 2DLAA 3C38A 1ATXA
chains in the Genus database with same CATH topology

3C30A 1Z99A 2K2XA 1SHIA 2HJ9C 3MCXA 2BDSA 2H9XA 4GV5A 1WQKA 1ZHHB 3LMSB 2JR3A 2SH1A 1B8WA 3KEZA 2QSFA 3D4UB 1APFA 4YIRA 2HJEA 2MUBA 2QSHA 1SH1A 1D6BA 1AHLA 2QSGA 1ZUFA 2B9KA 2IKEA 1ZLHB 2MN3A 2RNGA 1ZLIB 3MYVA 1H5OA 2IKDA 1ZUEA 1BDSA 2JTOA 2XXLA 1WXNA 2DLAA 3C38A 1ATXA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1Z99 A;  2K2X A;  1SHI A;  2BDS A;  2H9X A;  4GV5 A;  1WQK A;  3LMS B;  2SH1 A;  1B8W A;  3D4U B;  1APF A;  2MUB A;  1SH1 A;  1D6B A;  1AHL A;  1ZUF A;  1ZLH B;  2MN3 A;  2RNG A;  1ZLI B;  1H5O A;  1ZUE A;  2JTO A;  1WXN A;  1BDS A;  1ATX A; 
#chains in the Genus database with same CATH topology
 3C30 A;  1Z99 A;  2K2X A;  1SHI A;  2HJ9 C;  3MCX A;  2BDS A;  2H9X A;  4GV5 A;  1GL9 B;  1WQK A;  1ZHH B;  3LMS B;  2JR3 A;  2SH1 A;  1B8W A;  3KEZ A;  1GKU B;  2QSF A;  3D4U B;  1APF A;  4YIR A;  2HJE A;  2MUB A;  2QSH A;  1SH1 A;  1D6B A;  1AHL A;  2QSG A;  1ZUF A;  2B9K A;  2IKE A;  1EL6 A;  1ZLH B;  2MN3 A;  2RNG A;  1ZLI B;  3MYV A;  1H5O A;  1BDS A;  1ZUE A;  2IKD A;  2JTO A;  2XXL A;  1WXN A;  3IF4 A;  2DLA A;  3C38 A;  1ATX A; 
#chains in the Genus database with same CATH homology
 3C30 A;  1Z99 A;  2K2X A;  1SHI A;  2HJ9 C;  3MCX A;  2BDS A;  2H9X A;  4GV5 A;  1WQK A;  1ZHH B;  3LMS B;  2JR3 A;  2SH1 A;  1B8W A;  3KEZ A;  2QSF A;  3D4U B;  1APF A;  4YIR A;  2HJE A;  2MUB A;  2QSH A;  1SH1 A;  1D6B A;  1AHL A;  2QSG A;  1ZUF A;  2B9K A;  2IKE A;  1ZLH B;  2MN3 A;  2RNG A;  1ZLI B;  3MYV A;  1H5O A;  2IKD A;  1ZUE A;  1BDS A;  2JTO A;  2XXL A;  1WXN A;  2DLA A;  3C38 A;  1ATX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2K2XA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN