2QK7A

A covalent s-f heterodimer of staphylococcal gamma-hemolysin
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
268
structure length
259
Chain Sequence
AEIIKRTQDITSKRLAICQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHEKGKGDKSEFEITYGRNMDATYAYVTRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSIT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins.
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus aureus subsp. aureus
molecule keywords Gamma-hemolysin component A
total genus 61
structure length 259
sequence length 268
ec nomenclature
pdb deposition date 2007-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 2qk7A00
3ANZA 4P24A 5K59C 1PVLA 4IDJA 3ROHA 2YGTA 4I0NA 4U6VA 4YHDA 3M4EA 3B07A 4P1YA 3B07B 4P1YB 2LKFA 4P1XA 4J0OA 4P1XB 3M2LA 4TW1A 4TW1B 3M4DA 2QK7A 4IYCA 3LKFA 2QK7B 5K59A 3O44A 4IYTA 4Q7GA 1T5RA 4IYAA 7AHLA 3M3RA 1LKFA 4IZLA 4H56A
chains in the Genus database with same CATH superfamily
3ANZA 4P24A 5K59C 1PVLA 4IDJA 3ROHA 2YGTA 4I0NA 4U6VA 4YHDA 3M4EA 3B07A 4P1YA 3B07B 4P1YB 2LKFA 4P1XA 4J0OA 4P1XB 3M2LA 4TW1A 4TW1B 3M4DA 2QK7A 4IYCA 3LKFA 2QK7B 5K59A 3O44A 4IYTA 4Q7GA 1T5RA 1XEZA 4IYAA 7AHLA 3M3RA 1LKFA 4IZLA 4H56A
chains in the Genus database with same CATH topology
3ANZA 4P24A 5K59C 1PVLA 4IDJA 3ROHA 2YGTA 4I0NA 4U6VA 4YHDA 3M4EA 3B07A 4P1YA 3B07B 4P1YB 2LKFA 4P1XA 4J0OA 4P1XB 3M2LA 4TW1A 4TW1B 3M4DA 2QK7A 4IYCA 3LKFA 2QK7B 5K59A 3O44A 4IYTA 4Q7GA 1T5RA 4IYAA 7AHLA 3M3RA 1LKFA 4IZLA 4H56A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ANZ A;  4P24 A;  5K59 C;  1PVL A;  4IDJ A;  3ROH A;  2YGT A;  4I0N A;  4U6V A;  4YHD A;  3M4E A;  3B07 A;  4P1Y A;  3B07 B;  4P1Y B;  2LKF A;  4P1X A;  4J0O A;  4P1X B;  3M2L A;  4TW1 A;  4TW1 B;  3M4D A;  2QK7 A;  4IYC A;  3LKF A;  2QK7 B;  5K59 A;  3O44 A;  4IYT A;  4Q7G A;  1T5R A;  4IYA A;  7AHL A;  3M3R A;  1LKF A;  4IZL A;  4H56 A; 
#chains in the Genus database with same CATH topology
 3ANZ A;  4P24 A;  5K59 C;  1PVL A;  4IDJ A;  3ROH A;  2YGT A;  4I0N A;  4U6V A;  4YHD A;  3M4E A;  3B07 A;  4P1Y A;  3B07 B;  4P1Y B;  2LKF A;  4P1X A;  4J0O A;  4P1X B;  3M2L A;  4TW1 A;  4TW1 B;  3M4D A;  2QK7 A;  4IYC A;  3LKF A;  2QK7 B;  5K59 A;  3O44 A;  4IYT A;  4Q7G A;  1T5R A;  1XEZ A;  4IYA A;  7AHL A;  3M3R A;  1LKF A;  4IZL A;  4H56 A; 
#chains in the Genus database with same CATH homology
 3ANZ A;  4P24 A;  5K59 C;  1PVL A;  4IDJ A;  3ROH A;  2YGT A;  4I0N A;  4U6V A;  4YHD A;  3M4E A;  3B07 A;  4P1Y A;  3B07 B;  4P1Y B;  2LKF A;  4P1X A;  4J0O A;  4P1X B;  3M2L A;  4TW1 A;  4TW1 B;  3M4D A;  2QK7 A;  4IYC A;  3LKF A;  2QK7 B;  5K59 A;  3O44 A;  4IYT A;  4Q7G A;  1T5R A;  4IYA A;  7AHL A;  3M3R A;  1LKF A;  4IZL A;  4H56 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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