4IYTA

Structure of the y184a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPASQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords LukS-PV
publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
source organism Staphylococcus phage pvl
total genus 70
structure length 275
sequence length 282
ec nomenclature
pdb deposition date 2013-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4iytA00
4P1YA 4P1XA 1PVLA 4J0OA 5K59C 4IYCA 1T5RA 4U6VA 4Q7GA 3M2LA 4IZLA 3ROHA 1LKFA 4TW1A 3B07B 2QK7B 4P1YB 7AHLA 4YHDA 4P1XB 2YGTA 4IYAA 4H56A 4TW1B 4IYTA 2LKFA 3O44A 3M3RA 4P24A 5K59A 3M4DA 3LKFA 3M4EA 3ANZA 3B07A 4I0NA 2QK7A 4IDJA
chains in the Genus database with same CATH superfamily
4P1YA 4P1XA 1PVLA 1XEZA 4J0OA 5K59C 4IYCA 1T5RA 4U6VA 4Q7GA 3M2LA 4IZLA 3ROHA 1LKFA 4TW1A 3B07B 2QK7B 4P1YB 7AHLA 4YHDA 4P1XB 2YGTA 4IYAA 4H56A 4TW1B 4IYTA 2LKFA 3O44A 3M3RA 4P24A 5K59A 3M4DA 3LKFA 3M4EA 3ANZA 3B07A 4I0NA 2QK7A 4IDJA
chains in the Genus database with same CATH topology
4P1YA 4P1XA 1PVLA 4J0OA 5K59C 4IYCA 1T5RA 4U6VA 4Q7GA 3M2LA 4IZLA 3ROHA 1LKFA 4TW1A 3B07B 2QK7B 4P1YB 7AHLA 4YHDA 4P1XB 2YGTA 4IYAA 4H56A 4TW1B 4IYTA 2LKFA 3O44A 3M3RA 4P24A 5K59A 3M4DA 3LKFA 3M4EA 3ANZA 3B07A 4I0NA 2QK7A 4IDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1Y A;  4P1X A;  1PVL A;  4J0O A;  5K59 C;  4IYC A;  1T5R A;  4U6V A;  4Q7G A;  3M2L A;  4IZL A;  3ROH A;  1LKF A;  4TW1 A;  3B07 B;  2QK7 B;  4P1Y B;  7AHL A;  4YHD A;  4P1X B;  2YGT A;  4IYA A;  4H56 A;  4TW1 B;  4IYT A;  2LKF A;  3O44 A;  3M3R A;  4P24 A;  5K59 A;  3M4D A;  3LKF A;  3M4E A;  3ANZ A;  3B07 A;  4I0N A;  2QK7 A;  4IDJ A; 
#chains in the Genus database with same CATH topology
 4P1Y A;  4P1X A;  1PVL A;  1XEZ A;  4J0O A;  5K59 C;  4IYC A;  1T5R A;  4U6V A;  4Q7G A;  3M2L A;  4IZL A;  3ROH A;  1LKF A;  4TW1 A;  3B07 B;  2QK7 B;  4P1Y B;  7AHL A;  4YHD A;  4P1X B;  2YGT A;  4IYA A;  4H56 A;  4TW1 B;  4IYT A;  2LKF A;  3O44 A;  3M3R A;  4P24 A;  5K59 A;  3M4D A;  3LKF A;  3M4E A;  3ANZ A;  3B07 A;  4I0N A;  2QK7 A;  4IDJ A; 
#chains in the Genus database with same CATH homology
 4P1Y A;  4P1X A;  1PVL A;  4J0O A;  5K59 C;  4IYC A;  1T5R A;  4U6V A;  4Q7G A;  3M2L A;  4IZL A;  3ROH A;  1LKF A;  4TW1 A;  3B07 B;  2QK7 B;  4P1Y B;  7AHL A;  4YHD A;  4P1X B;  2YGT A;  4IYA A;  4H56 A;  4TW1 B;  4IYT A;  2LKF A;  3O44 A;  3M3R A;  4P24 A;  5K59 A;  3M4D A;  3LKF A;  3M4E A;  3ANZ A;  3B07 A;  4I0N A;  2QK7 A;  4IDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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