2QSHA

Crystal structure of rad4-rad23 bound to a mismatch dna
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
510
structure length
502
Chain Sequence
DARRTSRNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEKVFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNEGLYMRTWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPGCKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of DNA damage by the Rad4 nucleotide excision repair protein
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Saccharomyces cerevisiae
molecule keywords top strand of the mismatch DNA
total genus 146
structure length 502
sequence length 510
ec nomenclature
pdb deposition date 2007-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03835 Rad4 Rad4 transglutaminase-like domain
A PF10403 BHD_1 Rad4 beta-hairpin domain 1
A PF10405 BHD_3 Rad4 beta-hairpin domain 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.110 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2qshA02
2.20.20.120 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2qshA03
3.90.260.10 Alpha Beta Alpha-Beta Complex Coagulation Factor XIII; Chain A, domain 2 Transglutaminase-like 2qshA01
1L9MA 1EVUA 3S3JA 1L9NA 3S3SA 3LY6A 1EX0A 1FIEA 4YIRA 1NUFA 1NUDA 4KTYA 1QRKA 2QSGA 3S3PA 1G0DA 2QSFA 1GGTA 1KV3A 1F13A 2Q3ZA 1GGUA 2QSHA 1GGYA 4PYGA 1NUGA
chains in the Genus database with same CATH superfamily
2BDSA 1BDSA 1APFA 1L9MA 1GKUB 1EVUA 2DLAA 2K2XA 3D4UB 3S3JA 1L9NA 2MN3A 2HJ9C 2RNGA 1ATXA 1AHLA 3MYVA 3S3SA 1ZUFA 1WQKA 2IKDA 1ZLIB 2XXLA 3MCXA 3LY6A 1SHIA 1EX0A 3IF4A 2MUBA 1B8WA 4YIRA 1FIEA 2IKEA 1NUFA 1NUDA 1QRKA 4KTYA 1ZHHB 3C38A 1EL6A 2QSGA 4GV5A 3S3PA 2HJEA 1G0DA 1SH1A 1H5OA 2QSFA 1GGTA 3C30A 2H9XA 3LMSB 1F13A 1KV3A 2Q3ZA 1GL9B 2JTOA 1D6BA 1GGUA 2QSHA 1ZUEA 1WXNA 2B9KA 1ZLHB 2JR3A 2SH1A 3KEZA 1GGYA 4PYGA 1NUGA 1Z99A
chains in the Genus database with same CATH topology
2BDSA 1BDSA 1APFA 1L9MA 1EVUA 2DLAA 2K2XA 3D4UB 3S3JA 1L9NA 2MN3A 2HJ9C 2RNGA 1ATXA 1AHLA 3MYVA 3S3SA 1ZUFA 1WQKA 2IKDA 1ZLIB 2XXLA 3MCXA 3LY6A 1SHIA 1EX0A 2MUBA 1B8WA 4YIRA 1FIEA 2IKEA 1NUFA 1NUDA 1QRKA 4KTYA 1ZHHB 3C38A 2QSGA 4GV5A 3S3PA 2HJEA 1G0DA 1SH1A 1H5OA 2QSFA 1GGTA 3C30A 2H9XA 3LMSB 1F13A 1KV3A 2Q3ZA 1GGUA 2JTOA 1D6BA 2QSHA 1ZUEA 1WXNA 2B9KA 1ZLHB 2JR3A 2SH1A 3KEZA 1GGYA 4PYGA 1NUGA 1Z99A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L9M A;  1EVU A;  3S3J A;  1L9N A;  3S3S A;  3LY6 A;  1EX0 A;  1FIE A;  4YIR A;  1NUF A;  1NUD A;  4KTY A;  1QRK A;  2QSG A;  3S3P A;  1G0D A;  2QSF A;  1GGT A;  1KV3 A;  1F13 A;  2Q3Z A;  1GGU A;  2QSH A;  1GGY A;  4PYG A;  1NUG A; 
#chains in the Genus database with same CATH topology
 2BDS A;  1BDS A;  1APF A;  1L9M A;  1GKU B;  1EVU A;  2DLA A;  2K2X A;  3D4U B;  3S3J A;  1L9N A;  2MN3 A;  2HJ9 C;  2RNG A;  1ATX A;  1AHL A;  3MYV A;  3S3S A;  1ZUF A;  1WQK A;  2IKD A;  1ZLI B;  2XXL A;  3MCX A;  3LY6 A;  1SHI A;  1EX0 A;  3IF4 A;  2MUB A;  1B8W A;  4YIR A;  1FIE A;  2IKE A;  1NUF A;  1NUD A;  1QRK A;  4KTY A;  1ZHH B;  3C38 A;  1EL6 A;  2QSG A;  4GV5 A;  3S3P A;  2HJE A;  1G0D A;  1SH1 A;  1H5O A;  2QSF A;  1GGT A;  3C30 A;  2H9X A;  3LMS B;  1F13 A;  1KV3 A;  2Q3Z A;  1GL9 B;  2JTO A;  1D6B A;  1GGU A;  2QSH A;  1ZUE A;  1WXN A;  2B9K A;  1ZLH B;  2JR3 A;  2SH1 A;  3KEZ A;  1GGY A;  4PYG A;  1NUG A;  1Z99 A; 
#chains in the Genus database with same CATH homology
 2BDS A;  1BDS A;  1APF A;  1L9M A;  1EVU A;  2DLA A;  2K2X A;  3D4U B;  3S3J A;  1L9N A;  2MN3 A;  2HJ9 C;  2RNG A;  1ATX A;  1AHL A;  3MYV A;  3S3S A;  1ZUF A;  1WQK A;  2IKD A;  1ZLI B;  2XXL A;  3MCX A;  3LY6 A;  1SHI A;  1EX0 A;  2MUB A;  1B8W A;  4YIR A;  1FIE A;  2IKE A;  1NUF A;  1NUD A;  1QRK A;  4KTY A;  1ZHH B;  3C38 A;  2QSG A;  4GV5 A;  3S3P A;  2HJE A;  1G0D A;  1SH1 A;  1H5O A;  2QSF A;  1GGT A;  3C30 A;  2H9X A;  3LMS B;  1F13 A;  1KV3 A;  2Q3Z A;  1GGU A;  2JTO A;  1D6B A;  2QSH A;  1ZUE A;  1WXN A;  2B9K A;  1ZLH B;  2JR3 A;  2SH1 A;  3KEZ A;  1GGY A;  4PYG A;  1NUG A;  1Z99 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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