2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
molecule keywords Carboxypeptidase inhibitor
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
1ZLHB 1ZUEA 2MUBA 3D4UB 1D6BA 1ZLIB 2SH1A 1BDSA 1WXNA 1AHLA 2MN3A 1SHIA 1ZUFA 3LMSB 1Z99A 2BDSA 4GV5A 2RNGA 1H5OA 2H9XA 1B8WA 1SH1A 2JTOA 1ATXA 1WQKA 2K2XA 1APFA
chains in the Genus database with same CATH superfamily
3C30A 1GL9B 1GKUB 1ZLHB 1ZUEA 4YIRA 1ZHHB 2MUBA 2QSGA 3D4UB 1D6BA 1ZLIB 2SH1A 3MCXA 2IKDA 2QSFA 1BDSA 3IF4A 2XXLA 1WXNA 1AHLA 2MN3A 1SHIA 2JR3A 1EL6A 2IKEA 3C38A 1ZUFA 3LMSB 1Z99A 2BDSA 4GV5A 2QSHA 3KEZA 2RNGA 1H5OA 2H9XA 1B8WA 1SH1A 2JTOA 2DLAA 1ATXA 1WQKA 3MYVA 2HJ9C 2K2XA 2B9KA 2HJEA 1APFA
chains in the Genus database with same CATH topology
3C30A 1ZLHB 1ZUEA 4YIRA 1ZHHB 2MUBA 2QSGA 3D4UB 1D6BA 1ZLIB 2SH1A 3MCXA 2IKDA 2QSFA 1BDSA 2XXLA 1WXNA 1AHLA 2MN3A 1SHIA 2JR3A 2IKEA 3C38A 1ZUFA 3LMSB 1Z99A 2BDSA 4GV5A 2QSHA 3KEZA 2RNGA 1H5OA 2H9XA 1B8WA 1SH1A 2JTOA 2DLAA 1ATXA 1WQKA 3MYVA 2HJ9C 2K2XA 2B9KA 2HJEA 1APFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZLH B;  1ZUE A;  2MUB A;  3D4U B;  1D6B A;  1ZLI B;  2SH1 A;  1BDS A;  1WXN A;  1AHL A;  2MN3 A;  1SHI A;  1ZUF A;  3LMS B;  1Z99 A;  2BDS A;  4GV5 A;  2RNG A;  1H5O A;  2H9X A;  1B8W A;  1SH1 A;  2JTO A;  1ATX A;  1WQK A;  2K2X A;  1APF A; 
#chains in the Genus database with same CATH topology
 3C30 A;  1GL9 B;  1GKU B;  1ZLH B;  1ZUE A;  4YIR A;  1ZHH B;  2MUB A;  2QSG A;  3D4U B;  1D6B A;  1ZLI B;  2SH1 A;  3MCX A;  2IKD A;  2QSF A;  1BDS A;  3IF4 A;  2XXL A;  1WXN A;  1AHL A;  2MN3 A;  1SHI A;  2JR3 A;  1EL6 A;  2IKE A;  3C38 A;  1ZUF A;  3LMS B;  1Z99 A;  2BDS A;  4GV5 A;  2QSH A;  3KEZ A;  2RNG A;  1H5O A;  2H9X A;  1B8W A;  1SH1 A;  2JTO A;  2DLA A;  1ATX A;  1WQK A;  3MYV A;  2HJ9 C;  2K2X A;  2B9K A;  2HJE A;  1APF A; 
#chains in the Genus database with same CATH homology
 3C30 A;  1ZLH B;  1ZUE A;  4YIR A;  1ZHH B;  2MUB A;  2QSG A;  3D4U B;  1D6B A;  1ZLI B;  2SH1 A;  3MCX A;  2IKD A;  2QSF A;  1BDS A;  2XXL A;  1WXN A;  1AHL A;  2MN3 A;  1SHI A;  2JR3 A;  2IKE A;  3C38 A;  1ZUF A;  3LMS B;  1Z99 A;  2BDS A;  4GV5 A;  2QSH A;  3KEZ A;  2RNG A;  1H5O A;  2H9X A;  1B8W A;  1SH1 A;  2JTO A;  2DLA A;  1ATX A;  1WQK A;  3MYV A;  2HJ9 C;  2K2X A;  2B9K A;  2HJE A;  1APF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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