2K2XA

Solution structure of tick carboxypeptidase inhibitor at ph 3.5
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
molecule keywords Carboxypeptidase inhibitor
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2008-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA01
1Z99A 1ZLIB 1ATXA 1D6BA 1H5OA 2JTOA 2K2XA 2RNGA 4GV5A 1AHLA 2SH1A 3LMSB 1ZUFA 2MUBA 1SH1A 1WQKA 2BDSA 3D4UB 1WXNA 1BDSA 2MN3A 1B8WA 2H9XA 1APFA 1SHIA 1ZLHB 1ZUEA
chains in the Genus database with same CATH superfamily
1Z99A 2XXLA 2B9KA 2IKEA 3KEZA 1GL9B 1ZLIB 2HJEA 2IKDA 1ATXA 1D6BA 1H5OA 1ZHHB 2HJ9C 2QSGA 2JTOA 2K2XA 2RNGA 4GV5A 1AHLA 3C30A 2SH1A 2QSFA 3IF4A 2QSHA 2JR3A 3C38A 3LMSB 1EL6A 1ZUFA 2MUBA 2DLAA 1SH1A 3MYVA 1WQKA 2BDSA 3D4UB 1WXNA 1BDSA 2MN3A 1B8WA 2H9XA 3MCXA 4YIRA 1APFA 1GKUB 1SHIA 1ZLHB 1ZUEA
chains in the Genus database with same CATH topology
1Z99A 2XXLA 2B9KA 2IKEA 3KEZA 1ZLIB 2HJEA 2IKDA 1ATXA 1D6BA 1H5OA 1ZHHB 2HJ9C 2QSGA 2JTOA 2K2XA 2RNGA 4GV5A 1AHLA 3C30A 2SH1A 2QSFA 2QSHA 2JR3A 3C38A 3LMSB 1ZUFA 2MUBA 2DLAA 1SH1A 3MYVA 1WQKA 2BDSA 3D4UB 1WXNA 1BDSA 2MN3A 1B8WA 2H9XA 3MCXA 4YIRA 1APFA 1SHIA 1ZLHB 1ZUEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z99 A;  1ZLI B;  1ATX A;  1D6B A;  1H5O A;  2JTO A;  2K2X A;  2RNG A;  4GV5 A;  1AHL A;  2SH1 A;  3LMS B;  1ZUF A;  2MUB A;  1SH1 A;  1WQK A;  2BDS A;  3D4U B;  1WXN A;  1BDS A;  2MN3 A;  1B8W A;  2H9X A;  1APF A;  1SHI A;  1ZLH B;  1ZUE A; 
#chains in the Genus database with same CATH topology
 1Z99 A;  2XXL A;  2B9K A;  2IKE A;  3KEZ A;  1GL9 B;  1ZLI B;  2HJE A;  2IKD A;  1ATX A;  1D6B A;  1H5O A;  1ZHH B;  2HJ9 C;  2QSG A;  2JTO A;  2K2X A;  2RNG A;  4GV5 A;  1AHL A;  3C30 A;  2SH1 A;  2QSF A;  3IF4 A;  2QSH A;  2JR3 A;  3C38 A;  3LMS B;  1EL6 A;  1ZUF A;  2MUB A;  2DLA A;  1SH1 A;  3MYV A;  1WQK A;  2BDS A;  3D4U B;  1WXN A;  1BDS A;  2MN3 A;  1B8W A;  2H9X A;  3MCX A;  4YIR A;  1APF A;  1GKU B;  1SHI A;  1ZLH B;  1ZUE A; 
#chains in the Genus database with same CATH homology
 1Z99 A;  2XXL A;  2B9K A;  2IKE A;  3KEZ A;  1ZLI B;  2HJE A;  2IKD A;  1ATX A;  1D6B A;  1H5O A;  1ZHH B;  2HJ9 C;  2QSG A;  2JTO A;  2K2X A;  2RNG A;  4GV5 A;  1AHL A;  3C30 A;  2SH1 A;  2QSF A;  2QSH A;  2JR3 A;  3C38 A;  3LMS B;  1ZUF A;  2MUB A;  2DLA A;  1SH1 A;  3MYV A;  1WQK A;  2BDS A;  3D4U B;  1WXN A;  1BDS A;  2MN3 A;  1B8W A;  2H9X A;  3MCX A;  4YIR A;  1APF A;  1SHI A;  1ZLH B;  1ZUE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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