2KNYA

Fusion construct of cr17 from lrp-1 and apoe residues 130-149
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
80
structure length
80
Chain Sequence
GSKLEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTGSGSGSGSTEELRVRLASHLRKLRKRLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the minimal interface between ApoE and LRP.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords LRP-1, linker, Apo-E
total genus 8
structure length 80
sequence length 80
ec nomenclature
pdb deposition date 2009-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00057 Ldl_recept_a Low-density lipoprotein receptor domain class A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.400.10 Few Secondary Structures Irregular Low-density Lipoprotein Receptor Low-density Lipoprotein Receptor 2knyA00
1J8EA 1K7BA 2M96A 1XFEA 1F5YA 1N7DA 2LGPA 2KNYA 2JM4A 2I1PA 1D2LA 2FCWB 1LDLA 2FYLB 1D2JA 1LDRA 2FYJA 2KNXA 1JRFA 2M7PA 2M0PA 1CR8A
chains in the Genus database with same CATH superfamily
1J8EA 1K7BA 2M96A 1XFEA 1F5YA 1N7DA 2LGPA 2KNYA 2JM4A 2I1PA 1D2LA 2FCWB 1LDLA 2FYLB 1D2JA 1LDRA 2FYJA 2KNXA 1JRFA 2M7PA 2M0PA 1CR8A
chains in the Genus database with same CATH topology
1J8EA 1K7BA 2M96A 1XFEA 1F5YA 1N7DA 2LGPA 2KNYA 2JM4A 2I1PA 1D2LA 2FCWB 1LDLA 2FYLB 1D2JA 1LDRA 2FYJA 2KNXA 1JRFA 2M7PA 2M0PA 1CR8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J8E A;  1K7B A;  2M96 A;  1XFE A;  1F5Y A;  1N7D A;  2LGP A;  2KNY A;  2JM4 A;  2I1P A;  1D2L A;  2FCW B;  1LDL A;  2FYL B;  1D2J A;  1LDR A;  2FYJ A;  2KNX A;  1JRF A;  2M7P A;  2M0P A;  1CR8 A; 
#chains in the Genus database with same CATH topology
 1J8E A;  1K7B A;  2M96 A;  1XFE A;  1F5Y A;  1N7D A;  2LGP A;  2KNY A;  2JM4 A;  2I1P A;  1D2L A;  2FCW B;  1LDL A;  2FYL B;  1D2J A;  1LDR A;  2FYJ A;  2KNX A;  1JRF A;  2M7P A;  2M0P A;  1CR8 A; 
#chains in the Genus database with same CATH homology
 1J8E A;  1K7B A;  2M96 A;  1XFE A;  1F5Y A;  1N7D A;  2LGP A;  2KNY A;  2JM4 A;  2I1P A;  1D2L A;  2FCW B;  1LDL A;  2FYL B;  1D2J A;  1LDR A;  2FYJ A;  2KNX A;  1JRF A;  2M7P A;  2M0P A;  1CR8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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