2QSHA

Crystal structure of rad4-rad23 bound to a mismatch dna
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
510
structure length
502
Chain Sequence
DARRTSRNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEKVFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNEGLYMRTWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPGCKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of DNA damage by the Rad4 nucleotide excision repair protein
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Saccharomyces cerevisiae
molecule keywords top strand of the mismatch DNA
total genus 146
structure length 502
sequence length 510
ec nomenclature
pdb deposition date 2007-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03835 Rad4 Rad4 transglutaminase-like domain
A PF10403 BHD_1 Rad4 beta-hairpin domain 1
A PF10405 BHD_3 Rad4 beta-hairpin domain 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.110 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2qshA02
2.20.20.120 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2qshA03
3.90.260.10 Alpha Beta Alpha-Beta Complex Coagulation Factor XIII; Chain A, domain 2 Transglutaminase-like 2qshA01
2QSHA 4KTYA 1GGTA 3S3JA 1QRKA 1EX0A 2QSFA 1G0DA 1GGYA 3S3SA 1NUGA 1EVUA 4YIRA 1NUFA 1L9NA 4PYGA 3S3PA 1KV3A 1NUDA 1F13A 1FIEA 2QSGA 1L9MA 2Q3ZA 1GGUA 3LY6A
chains in the Genus database with same CATH superfamily
2DLAA 3MCXA 2QSHA 4KTYA 1ZUFA 1SH1A 1D6BA 1GGTA 3S3JA 1QRKA 2MUBA 2B9KA 1ZHHB 2JR3A 2QSFA 3LMSB 1EX0A 1G0DA 1GGYA 3C38A 2IKDA 3KEZA 1ZUEA 3S3SA 2IKEA 3MYVA 1NUGA 2RNGA 1ZLIB 1GL9B 1ATXA 1GKUB 2JTOA 1AHLA 1WQKA 4YIRA 1EVUA 2HJ9C 3LY6A 1NUFA 1L9NA 2K2XA 3D4UB 1EL6A 2SH1A 3IF4A 2H9XA 1H5OA 4PYGA 3S3PA 2HJEA 1KV3A 1NUDA 1F13A 1BDSA 2XXLA 4GV5A 1ZLHB 1FIEA 1B8WA 1SHIA 1Z99A 2QSGA 2MN3A 1APFA 1L9MA 2Q3ZA 3C30A 1GGUA 1WXNA 2BDSA
chains in the Genus database with same CATH topology
2DLAA 3MCXA 2QSHA 4KTYA 1ZUFA 1SH1A 1D6BA 1GGTA 3S3JA 1QRKA 2MUBA 2B9KA 1ZHHB 2JR3A 2QSFA 3LMSB 1EX0A 1G0DA 1GGYA 3C38A 2IKDA 3KEZA 1ZUEA 3S3SA 2IKEA 3MYVA 1NUGA 2RNGA 1ZLIB 1ATXA 2JTOA 1AHLA 1WQKA 4YIRA 1EVUA 2HJ9C 3LY6A 1NUFA 1L9NA 2K2XA 3D4UB 2SH1A 1H5OA 2H9XA 4PYGA 3S3PA 2HJEA 1KV3A 1NUDA 1F13A 1BDSA 2XXLA 4GV5A 1ZLHB 1FIEA 1B8WA 1SHIA 1Z99A 2QSGA 2MN3A 1APFA 1L9MA 2Q3ZA 3C30A 1GGUA 1WXNA 2BDSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QSH A;  4KTY A;  1GGT A;  3S3J A;  1QRK A;  1EX0 A;  2QSF A;  1G0D A;  1GGY A;  3S3S A;  1NUG A;  1EVU A;  4YIR A;  1NUF A;  1L9N A;  4PYG A;  3S3P A;  1KV3 A;  1NUD A;  1F13 A;  1FIE A;  2QSG A;  1L9M A;  2Q3Z A;  1GGU A;  3LY6 A; 
#chains in the Genus database with same CATH topology
 2DLA A;  3MCX A;  2QSH A;  4KTY A;  1ZUF A;  1SH1 A;  1D6B A;  1GGT A;  3S3J A;  1QRK A;  2MUB A;  2B9K A;  1ZHH B;  2JR3 A;  2QSF A;  3LMS B;  1EX0 A;  1G0D A;  1GGY A;  3C38 A;  2IKD A;  3KEZ A;  1ZUE A;  3S3S A;  2IKE A;  3MYV A;  1NUG A;  2RNG A;  1ZLI B;  1GL9 B;  1ATX A;  1GKU B;  2JTO A;  1AHL A;  1WQK A;  4YIR A;  1EVU A;  2HJ9 C;  3LY6 A;  1NUF A;  1L9N A;  2K2X A;  3D4U B;  1EL6 A;  2SH1 A;  3IF4 A;  2H9X A;  1H5O A;  4PYG A;  3S3P A;  2HJE A;  1KV3 A;  1NUD A;  1F13 A;  1BDS A;  2XXL A;  4GV5 A;  1ZLH B;  1FIE A;  1B8W A;  1SHI A;  1Z99 A;  2QSG A;  2MN3 A;  1APF A;  1L9M A;  2Q3Z A;  3C30 A;  1GGU A;  1WXN A;  2BDS A; 
#chains in the Genus database with same CATH homology
 2DLA A;  3MCX A;  2QSH A;  4KTY A;  1ZUF A;  1SH1 A;  1D6B A;  1GGT A;  3S3J A;  1QRK A;  2MUB A;  2B9K A;  1ZHH B;  2JR3 A;  2QSF A;  3LMS B;  1EX0 A;  1G0D A;  1GGY A;  3C38 A;  2IKD A;  3KEZ A;  1ZUE A;  3S3S A;  2IKE A;  3MYV A;  1NUG A;  2RNG A;  1ZLI B;  1ATX A;  2JTO A;  1AHL A;  1WQK A;  4YIR A;  1EVU A;  2HJ9 C;  3LY6 A;  1NUF A;  1L9N A;  2K2X A;  3D4U B;  2SH1 A;  1H5O A;  2H9X A;  4PYG A;  3S3P A;  2HJE A;  1KV3 A;  1NUD A;  1F13 A;  1BDS A;  2XXL A;  4GV5 A;  1ZLH B;  1FIE A;  1B8W A;  1SHI A;  1Z99 A;  2QSG A;  2MN3 A;  1APF A;  1L9M A;  2Q3Z A;  3C30 A;  1GGU A;  1WXN A;  2BDS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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