3LMSB

Structure of human activated thrombin-activatable fibrinolysis inhibitor, tafia, in complex with tick-derived funnelin inhibitor, tci.
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
74
structure length
74
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rhipicephalus bursa
molecule keywords Carboxypeptidase B2
total genus 18
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2010-02-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 3lmsB02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 3lmsB01
2BDSA 1ZLHB 1ATXA 1H5OA 1AHLA 1SHIA 2MN3A 2H9XA 2SH1A 1ZLIB 1WXNA 3LMSB 2JTOA 2RNGA 1SH1A 1WQKA 1B8WA 3D4UB 2K2XA 1D6BA 1Z99A 2MUBA 1ZUEA 1APFA 4GV5A 1BDSA 1ZUFA
chains in the Genus database with same CATH superfamily
2DLAA 2BDSA 3MYVA 1ZLHB 1GKUB 2IKDA 3MCXA 1ATXA 1H5OA 1AHLA 1SHIA 2MN3A 1EL6A 3KEZA 2H9XA 2QSGA 2SH1A 1ZLIB 1WXNA 3LMSB 2JTOA 2QSFA 2RNGA 2HJEA 2QSHA 1SH1A 2B9KA 2JR3A 1WQKA 2XXLA 1B8WA 1BDSA 2HJ9C 3C38A 2K2XA 3D4UB 3IF4A 1D6BA 1Z99A 2MUBA 3C30A 1ZUEA 1APFA 2IKEA 4GV5A 1ZHHB 1GL9B 1ZUFA 4YIRA
chains in the Genus database with same CATH topology
2DLAA 2BDSA 3MYVA 1ZLHB 2IKDA 3MCXA 1ATXA 1H5OA 1AHLA 1SHIA 2MN3A 3KEZA 2H9XA 2QSGA 2SH1A 1ZLIB 1WXNA 3LMSB 2JTOA 2QSFA 2RNGA 2HJEA 2QSHA 1SH1A 2B9KA 2JR3A 1WQKA 2XXLA 1B8WA 2HJ9C 3C38A 2K2XA 3D4UB 1D6BA 1Z99A 2MUBA 3C30A 1ZUEA 1APFA 2IKEA 4GV5A 1ZHHB 1BDSA 1ZUFA 4YIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BDS A;  1ZLH B;  1ATX A;  1H5O A;  1AHL A;  1SHI A;  2MN3 A;  2H9X A;  2SH1 A;  1ZLI B;  1WXN A;  3LMS B;  2JTO A;  2RNG A;  1SH1 A;  1WQK A;  1B8W A;  3D4U B;  2K2X A;  1D6B A;  1Z99 A;  2MUB A;  1ZUE A;  1APF A;  4GV5 A;  1BDS A;  1ZUF A; 
#chains in the Genus database with same CATH topology
 2DLA A;  2BDS A;  3MYV A;  1ZLH B;  1GKU B;  2IKD A;  3MCX A;  1ATX A;  1H5O A;  1AHL A;  1SHI A;  2MN3 A;  1EL6 A;  3KEZ A;  2H9X A;  2QSG A;  2SH1 A;  1ZLI B;  1WXN A;  3LMS B;  2JTO A;  2QSF A;  2RNG A;  2HJE A;  2QSH A;  1SH1 A;  2B9K A;  2JR3 A;  1WQK A;  2XXL A;  1B8W A;  1BDS A;  2HJ9 C;  3C38 A;  2K2X A;  3D4U B;  3IF4 A;  1D6B A;  1Z99 A;  2MUB A;  3C30 A;  1ZUE A;  1APF A;  2IKE A;  4GV5 A;  1ZHH B;  1GL9 B;  1ZUF A;  4YIR A; 
#chains in the Genus database with same CATH homology
 2DLA A;  2BDS A;  3MYV A;  1ZLH B;  2IKD A;  3MCX A;  1ATX A;  1H5O A;  1AHL A;  1SHI A;  2MN3 A;  3KEZ A;  2H9X A;  2QSG A;  2SH1 A;  1ZLI B;  1WXN A;  3LMS B;  2JTO A;  2QSF A;  2RNG A;  2HJE A;  2QSH A;  1SH1 A;  2B9K A;  2JR3 A;  1WQK A;  2XXL A;  1B8W A;  2HJ9 C;  3C38 A;  2K2X A;  3D4U B;  1D6B A;  1Z99 A;  2MUB A;  3C30 A;  1ZUE A;  1APF A;  2IKE A;  4GV5 A;  1ZHH B;  1BDS A;  1ZUF A;  4YIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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