3LMSB

Structure of human activated thrombin-activatable fibrinolysis inhibitor, tafia, in complex with tick-derived funnelin inhibitor, tci.
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
74
structure length
74
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor
pubmed doi rcsb
molecule keywords Carboxypeptidase B2
molecule tags Hydrolase/hydrolase inhibitor
source organism Rhipicephalus bursa
total genus 18
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2010-02-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 3lmsB02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 3lmsB01
2K2XA 2SH1A 1Z99A 1BDSA 2MUBA 2H9XA 2JTOA 1WQKA 3LMSB 1D6BA 1ZLHB 1SHIA 2RNGA 2MN3A 1WXNA 4GV5A 3D4UB 1AHLA 1APFA 1ATXA 1B8WA 1ZUFA 1SH1A 1ZLIB 1H5OA 2BDSA 1ZUEA
chains in the Genus database with same CATH superfamily
2K2XA 2SH1A 1Z99A 4YIRA 2IKDA 2DLAA 1BDSA 1GL9B 2H9XA 2JTOA 2MUBA 2QSFA 3C30A 2HJ9C 2B9KA 2QSGA 1WQKA 2JR3A 3LMSB 1EL6A 2IKEA 1D6BA 1ZLHB 1SHIA 2RNGA 3C38A 2MN3A 1WXNA 1GKUB 4GV5A 3MYVA 3D4UB 2QSHA 1AHLA 3IF4A 1APFA 1ATXA 1B8WA 1ZUFA 3KEZA 1SH1A 1ZLIB 1H5OA 1ZHHB 3MCXA 2HJEA 2BDSA 2XXLA 1ZUEA
chains in the Genus database with same CATH topology
2K2XA 2SH1A 1Z99A 4YIRA 2IKDA 2DLAA 1BDSA 2H9XA 2JTOA 2MUBA 2QSFA 3C30A 2HJ9C 2B9KA 2QSGA 1WQKA 2JR3A 3LMSB 2IKEA 1D6BA 1ZLHB 1SHIA 2RNGA 3C38A 2MN3A 1WXNA 4GV5A 3MYVA 3D4UB 2QSHA 1AHLA 1APFA 1ATXA 1B8WA 1ZUFA 3KEZA 1SH1A 1ZLIB 1H5OA 1ZHHB 3MCXA 2HJEA 2BDSA 2XXLA 1ZUEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K2X A;  2SH1 A;  1Z99 A;  1BDS A;  2MUB A;  2H9X A;  2JTO A;  1WQK A;  3LMS B;  1D6B A;  1ZLH B;  1SHI A;  2RNG A;  2MN3 A;  1WXN A;  4GV5 A;  3D4U B;  1AHL A;  1APF A;  1ATX A;  1B8W A;  1ZUF A;  1SH1 A;  1ZLI B;  1H5O A;  2BDS A;  1ZUE A; 
#chains in the Genus database with same CATH topology
 2K2X A;  2SH1 A;  1Z99 A;  4YIR A;  2IKD A;  2DLA A;  1BDS A;  1GL9 B;  2H9X A;  2JTO A;  2MUB A;  2QSF A;  3C30 A;  2HJ9 C;  2B9K A;  2QSG A;  1WQK A;  2JR3 A;  3LMS B;  1EL6 A;  2IKE A;  1D6B A;  1ZLH B;  1SHI A;  2RNG A;  3C38 A;  2MN3 A;  1WXN A;  1GKU B;  4GV5 A;  3MYV A;  3D4U B;  2QSH A;  1AHL A;  3IF4 A;  1APF A;  1ATX A;  1B8W A;  1ZUF A;  3KEZ A;  1SH1 A;  1ZLI B;  1H5O A;  1ZHH B;  3MCX A;  2HJE A;  2BDS A;  2XXL A;  1ZUE A; 
#chains in the Genus database with same CATH homology
 2K2X A;  2SH1 A;  1Z99 A;  4YIR A;  2IKD A;  2DLA A;  1BDS A;  2H9X A;  2JTO A;  2MUB A;  2QSF A;  3C30 A;  2HJ9 C;  2B9K A;  2QSG A;  1WQK A;  2JR3 A;  3LMS B;  2IKE A;  1D6B A;  1ZLH B;  1SHI A;  2RNG A;  3C38 A;  2MN3 A;  1WXN A;  4GV5 A;  3MYV A;  3D4U B;  2QSH A;  1AHL A;  1APF A;  1ATX A;  1B8W A;  1ZUF A;  3KEZ A;  1SH1 A;  1ZLI B;  1H5O A;  1ZHH B;  3MCX A;  2HJE A;  2BDS A;  2XXL A;  1ZUE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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