3M2LA

Crystal structure of the m113f mutant of alpha-hemolysin
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYFSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
molecule keywords Alpha-hemolysin
molecule tags Toxin
source organism Staphylococcus aureus
total genus 58
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m2lA00
4J0OA 3M4EA 2QK7B 4YHDA 3O44A 3ANZA 4H56A 5K59C 2QK7A 4TW1B 4I0NA 4IYTA 4IDJA 2YGTA 3M2LA 4TW1A 2LKFA 4IYAA 5K59A 3M4DA 4P1YB 1PVLA 4P1XB 4Q7GA 4P1YA 1T5RA 4IYCA 3B07B 4P1XA 7AHLA 3ROHA 3M3RA 4IZLA 4P24A 3LKFA 4U6VA 3B07A 1LKFA
chains in the Genus database with same CATH superfamily
4J0OA 3M4EA 2QK7B 4YHDA 3O44A 3ANZA 4H56A 5K59C 2QK7A 4TW1B 4I0NA 4IYTA 4IDJA 2YGTA 1XEZA 3M2LA 4TW1A 2LKFA 4IYAA 5K59A 3M4DA 4P1YB 1PVLA 4P1XB 4Q7GA 4P1YA 1T5RA 4IYCA 3B07B 4P1XA 7AHLA 3ROHA 3M3RA 4IZLA 4P24A 3LKFA 4U6VA 3B07A 1LKFA
chains in the Genus database with same CATH topology
4J0OA 3M4EA 2QK7B 4YHDA 3O44A 3ANZA 4H56A 5K59C 2QK7A 4TW1B 4I0NA 4IYTA 4IDJA 2YGTA 3M2LA 4TW1A 2LKFA 4IYAA 5K59A 3M4DA 4P1YB 1PVLA 4P1XB 4Q7GA 4P1YA 1T5RA 4IYCA 3B07B 4P1XA 7AHLA 3ROHA 3M3RA 4IZLA 4P24A 3LKFA 4U6VA 3B07A 1LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J0O A;  3M4E A;  2QK7 B;  4YHD A;  3O44 A;  3ANZ A;  4H56 A;  5K59 C;  2QK7 A;  4TW1 B;  4I0N A;  4IYT A;  4IDJ A;  2YGT A;  3M2L A;  4TW1 A;  2LKF A;  4IYA A;  5K59 A;  3M4D A;  4P1Y B;  1PVL A;  4P1X B;  4Q7G A;  4P1Y A;  1T5R A;  4IYC A;  3B07 B;  4P1X A;  7AHL A;  3ROH A;  3M3R A;  4IZL A;  4P24 A;  3LKF A;  4U6V A;  3B07 A;  1LKF A; 
#chains in the Genus database with same CATH topology
 4J0O A;  3M4E A;  2QK7 B;  4YHD A;  3O44 A;  3ANZ A;  4H56 A;  5K59 C;  2QK7 A;  4TW1 B;  4I0N A;  4IYT A;  4IDJ A;  2YGT A;  1XEZ A;  3M2L A;  4TW1 A;  2LKF A;  4IYA A;  5K59 A;  3M4D A;  4P1Y B;  1PVL A;  4P1X B;  4Q7G A;  4P1Y A;  1T5R A;  4IYC A;  3B07 B;  4P1X A;  7AHL A;  3ROH A;  3M3R A;  4IZL A;  4P24 A;  3LKF A;  4U6V A;  3B07 A;  1LKF A; 
#chains in the Genus database with same CATH homology
 4J0O A;  3M4E A;  2QK7 B;  4YHD A;  3O44 A;  3ANZ A;  4H56 A;  5K59 C;  2QK7 A;  4TW1 B;  4I0N A;  4IYT A;  4IDJ A;  2YGT A;  3M2L A;  4TW1 A;  2LKF A;  4IYA A;  5K59 A;  3M4D A;  4P1Y B;  1PVL A;  4P1X B;  4Q7G A;  4P1Y A;  1T5R A;  4IYC A;  3B07 B;  4P1X A;  7AHL A;  3ROH A;  3M3R A;  4IZL A;  4P24 A;  3LKF A;  4U6V A;  3B07 A;  1LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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