3M3RA

Crystal structure of the m113f alpha-hemolysin mutant complexed with beta-cyclodextrin
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYFSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
molecule tags Cell invasion
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 56
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m3rA00
5K59C 1PVLA 3M2LA 2YGTA 2QK7B 2QK7A 4Q7GA 4IYCA 4H56A 1T5RA 4P24A 1LKFA 4I0NA 4TW1B 4TW1A 4J0OA 3M3RA 3M4DA 2LKFA 3O44A 4U6VA 4P1YB 4P1YA 4YHDA 4P1XB 4P1XA 4IZLA 5K59A 3B07B 3B07A 3LKFA 3M4EA 4IDJA 4IYTA 7AHLA 3ANZA 3ROHA 4IYAA
chains in the Genus database with same CATH superfamily
5K59C 1PVLA 3M2LA 2YGTA 2QK7B 2QK7A 4Q7GA 4IYCA 4H56A 1T5RA 4P24A 1XEZA 1LKFA 4I0NA 4TW1B 4TW1A 4J0OA 3M3RA 3M4DA 2LKFA 3O44A 4U6VA 4P1YB 4P1YA 4YHDA 4P1XB 4P1XA 4IZLA 5K59A 3B07B 3B07A 3LKFA 3M4EA 4IDJA 4IYTA 7AHLA 3ANZA 3ROHA 4IYAA
chains in the Genus database with same CATH topology
5K59C 1PVLA 3M2LA 2YGTA 2QK7B 2QK7A 4Q7GA 4IYCA 4H56A 1T5RA 4P24A 1LKFA 4I0NA 4TW1B 4TW1A 4J0OA 3M3RA 3M4DA 2LKFA 3O44A 4U6VA 4P1YB 4P1YA 4YHDA 4P1XB 4P1XA 4IZLA 5K59A 3B07B 3B07A 3LKFA 3M4EA 4IDJA 4IYTA 7AHLA 3ANZA 3ROHA 4IYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K59 C;  1PVL A;  3M2L A;  2YGT A;  2QK7 B;  2QK7 A;  4Q7G A;  4IYC A;  4H56 A;  1T5R A;  4P24 A;  1LKF A;  4I0N A;  4TW1 B;  4TW1 A;  4J0O A;  3M3R A;  3M4D A;  2LKF A;  3O44 A;  4U6V A;  4P1Y B;  4P1Y A;  4YHD A;  4P1X B;  4P1X A;  4IZL A;  5K59 A;  3B07 B;  3B07 A;  3LKF A;  3M4E A;  4IDJ A;  4IYT A;  7AHL A;  3ANZ A;  3ROH A;  4IYA A; 
#chains in the Genus database with same CATH topology
 5K59 C;  1PVL A;  3M2L A;  2YGT A;  2QK7 B;  2QK7 A;  4Q7G A;  4IYC A;  4H56 A;  1T5R A;  4P24 A;  1XEZ A;  1LKF A;  4I0N A;  4TW1 B;  4TW1 A;  4J0O A;  3M3R A;  3M4D A;  2LKF A;  3O44 A;  4U6V A;  4P1Y B;  4P1Y A;  4YHD A;  4P1X B;  4P1X A;  4IZL A;  5K59 A;  3B07 B;  3B07 A;  3LKF A;  3M4E A;  4IDJ A;  4IYT A;  7AHL A;  3ANZ A;  3ROH A;  4IYA A; 
#chains in the Genus database with same CATH homology
 5K59 C;  1PVL A;  3M2L A;  2YGT A;  2QK7 B;  2QK7 A;  4Q7G A;  4IYC A;  4H56 A;  1T5R A;  4P24 A;  1LKF A;  4I0N A;  4TW1 B;  4TW1 A;  4J0O A;  3M3R A;  3M4D A;  2LKF A;  3O44 A;  4U6V A;  4P1Y B;  4P1Y A;  4YHD A;  4P1X B;  4P1X A;  4IZL A;  5K59 A;  3B07 B;  3B07 A;  3LKF A;  3M4E A;  4IDJ A;  4IYT A;  7AHL A;  3ANZ A;  3ROH A;  4IYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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