3M4DA

Crystal structure of the m113n mutant of alpha-hemolysin
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYNSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
molecule tags Cell invasion
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 61
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m4dA00
3B07A 3B07B 7AHLA 1T5RA 3M3RA 5K59C 4IDJA 3ANZA 1PVLA 3O44A 4TW1A 2YGTA 3LKFA 4TW1B 1LKFA 4IZLA 4H56A 2QK7A 4IYTA 4IYAA 4U6VA 2QK7B 3M4EA 3ROHA 4P24A 4P1XA 4J0OA 4YHDA 5K59A 4P1YB 4I0NA 3M2LA 4P1XB 4P1YA 4IYCA 2LKFA 4Q7GA 3M4DA
chains in the Genus database with same CATH superfamily
3B07A 3B07B 7AHLA 1T5RA 3M3RA 5K59C 4IDJA 3ANZA 1PVLA 3O44A 4TW1A 2YGTA 3LKFA 4TW1B 1LKFA 4IZLA 4H56A 2QK7A 4IYTA 4IYAA 4U6VA 2QK7B 3M4EA 3ROHA 4P24A 4P1XA 4J0OA 4YHDA 1XEZA 5K59A 4P1YB 4I0NA 3M2LA 4P1XB 4P1YA 4IYCA 2LKFA 4Q7GA 3M4DA
chains in the Genus database with same CATH topology
3B07A 3B07B 7AHLA 1T5RA 3M3RA 5K59C 4IDJA 3ANZA 1PVLA 3O44A 4TW1A 2YGTA 3LKFA 4TW1B 1LKFA 4IZLA 4H56A 2QK7A 4IYTA 4IYAA 4U6VA 2QK7B 3M4EA 3ROHA 4P24A 4P1XA 4J0OA 4YHDA 5K59A 4P1YB 4I0NA 3M2LA 4P1XB 4P1YA 4IYCA 2LKFA 4Q7GA 3M4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B07 A;  3B07 B;  7AHL A;  1T5R A;  3M3R A;  5K59 C;  4IDJ A;  3ANZ A;  1PVL A;  3O44 A;  4TW1 A;  2YGT A;  3LKF A;  4TW1 B;  1LKF A;  4IZL A;  4H56 A;  2QK7 A;  4IYT A;  4IYA A;  4U6V A;  2QK7 B;  3M4E A;  3ROH A;  4P24 A;  4P1X A;  4J0O A;  4YHD A;  5K59 A;  4P1Y B;  4I0N A;  3M2L A;  4P1X B;  4P1Y A;  4IYC A;  2LKF A;  4Q7G A;  3M4D A; 
#chains in the Genus database with same CATH topology
 3B07 A;  3B07 B;  7AHL A;  1T5R A;  3M3R A;  5K59 C;  4IDJ A;  3ANZ A;  1PVL A;  3O44 A;  4TW1 A;  2YGT A;  3LKF A;  4TW1 B;  1LKF A;  4IZL A;  4H56 A;  2QK7 A;  4IYT A;  4IYA A;  4U6V A;  2QK7 B;  3M4E A;  3ROH A;  4P24 A;  4P1X A;  4J0O A;  4YHD A;  1XEZ A;  5K59 A;  4P1Y B;  4I0N A;  3M2L A;  4P1X B;  4P1Y A;  4IYC A;  2LKF A;  4Q7G A;  3M4D A; 
#chains in the Genus database with same CATH homology
 3B07 A;  3B07 B;  7AHL A;  1T5R A;  3M3R A;  5K59 C;  4IDJ A;  3ANZ A;  1PVL A;  3O44 A;  4TW1 A;  2YGT A;  3LKF A;  4TW1 B;  1LKF A;  4IZL A;  4H56 A;  2QK7 A;  4IYT A;  4IYA A;  4U6V A;  2QK7 B;  3M4E A;  3ROH A;  4P24 A;  4P1X A;  4J0O A;  4YHD A;  5K59 A;  4P1Y B;  4I0N A;  3M2L A;  4P1X B;  4P1Y A;  4IYC A;  2LKF A;  4Q7G A;  3M4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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